|
|
amine metabolic process
|
GO:0009308 |
44 |
0.996
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.994
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.992
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.983
|
Human |
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.983
|
Human |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.978
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.972
|
Human |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.969
|
Human |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.965
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.949
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.943
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.943
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.931
|
Human |
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.909
|
Human |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.906
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.895
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.893
|
Human |
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.878
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.866
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
41 |
0.866
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.866
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.860
|
Human |
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
4 |
0.847
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.801
|
Human |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.793
|
Human |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.788
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.782
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.765
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.759
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.756
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.753
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.745
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.728
|
Human |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.721
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.720
|
Human |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.707
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.698
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.643
|
Human |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.643
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.638
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.568
|
Rat |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.534
|
Human |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.529
|
Human |
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.516
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.509
|
Human Rat |
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.502
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.502
|
Human Rat |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.492
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.490
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.484
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.484
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.477
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.474
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.472
|
Human |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.471
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.458
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.450
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.441
|
Human |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.438
|
Human |
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.415
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.414
|
Human |
|
|
positive regulation of mast cell activation
|
GO:0033005 |
2 |
0.413
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.397
|
Rat |
|
|
interferon alpha biosynthetic process
|
GO:0045349 |
4 |
0.388
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.366
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.366
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.357
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.351
|
Human |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.349
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.347
|
Human |
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.346
|
Human |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.345
|
Human |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.336
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.335
|
Human |
|
|
tissue migration
|
GO:0090130 |
119 |
0.329
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.326
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.318
|
Human Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.314
|
Rat |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.312
|
Human |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.309
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.309
|
Human Fly |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.309
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.308
|
Human |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.298
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.289
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.287
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.284
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.283
|
Human |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.276
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.274
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.274
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.274
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.271
|
Human |
|
|
regulation of interferon alpha biosynthetic process
|
GO:0045354 |
4 |
0.270
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.269
|
Human Rat |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.259
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.255
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.254
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.254
|
Fly |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.251
|
Human |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.249
|
Human |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.246
|
Human Rat |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.243
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.242
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.240
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.239
|
Human |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.236
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.231
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.230
|
Rat |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.226
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.226
|
Human |
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.226
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.225
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.219
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.216
|
Human |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.213
|
Human |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.212
|
Human |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.210
|
Human |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.210
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.208
|
Human |
|
|
memory
|
GO:0007613 |
3 |
0.206
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.203
|
Human Rat |
|
|
platelet activation
|
GO:0030168 |
44 |
0.202
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.201
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.198
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.194
|
Human |
|
|
regulation of mast cell degranulation
|
GO:0043304 |
3 |
0.193
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.191
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.190
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.183
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.182
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.178
|
Human |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.175
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.174
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.173
|
Human Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.173
|
Human Rat |
|
|
associative learning
|
GO:0008306 |
1 |
0.172
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.171
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.171
|
Rat |
|
|
t cell activation
|
GO:0042110 |
99 |
0.170
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.168
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.166
|
Human |
|
|
serotonin transport
|
GO:0006837 |
3 |
0.166
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.165
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.164
|
Human |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.161
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.160
|
Rat |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.151
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.151
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.150
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.149
|
Human |
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.148
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.146
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.146
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.146
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.144
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.144
|
Rat |
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
1 |
0.142
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.142
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.142
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.139
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.137
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.136
|
Human |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.133
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.133
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.132
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.132
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.131
|
Human |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.130
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.129
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.128
|
Human Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.128
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.127
|
Human |
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.126
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.125
|
Human |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.125
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.125
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.123
|
Human |
|
|
negative regulation of protein tyrosine kinase activity
|
GO:0061099 |
13 |
0.122
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.121
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.121
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.120
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.119
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.119
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.118
|
Human |
|
|
amide transport
|
GO:0042886 |
76 |
0.118
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.117
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.117
|
Human Rat |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.117
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.116
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.115
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.114
|
Human Fly |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.114
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.111
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.109
|
Human |
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.109
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.109
|
Human |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.108
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.108
|
Human Fly |
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.108
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.107
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.107
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.106
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.105
|
Human |
|
|
defense response to virus
|
GO:0051607 |
71 |
0.102
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.101
|
Rat |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.100
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.096
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.096
|
Human |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.096
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.095
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.094
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.093
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.093
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.093
|
Mouse |
|
|
immune system development
|
GO:0002520 |
195 |
0.093
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.092
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.092
|
Human |
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.090
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.089
|
Human |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.089
|
Human |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.088
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.088
|
Fly |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.087
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.085
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.085
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.084
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.084
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.083
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.082
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.082
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.081
|
Human |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.081
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.081
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.080
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.080
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.080
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.079
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.079
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.079
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.079
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.079
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.078
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.078
|
Human Rat |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.077
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.077
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.077
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
4 |
0.076
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.076
|
Human |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.076
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.075
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.075
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.074
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.074
|
Human |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.073
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.073
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.073
|
Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.072
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.072
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.072
|
Human Mouse Fly |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.071
|
Human |
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.071
|
Human |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.071
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.070
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.070
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.070
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.070
|
Human |
|
|
positive regulation of interferon alpha biosynthetic process
|
GO:0045356 |
4 |
0.070
|
|
|
|
macrophage activation involved in immune response
|
GO:0002281 |
1 |
0.069
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.069
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.067
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.067
|
Rat |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.067
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.066
|
Human |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.065
|
Human Fly |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.065
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.065
|
|
|
|
platelet degranulation
|
GO:0002576 |
2 |
0.065
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.065
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.065
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.064
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.064
|
Fly |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.063
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.063
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.063
|
Human |
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.062
|
Human |
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.062
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.062
|
Human |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.061
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.061
|
Human |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.060
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.060
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.060
|
|
|
|
response to triacyl bacterial lipopeptide
|
GO:0071725 |
2 |
0.060
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.060
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.059
|
Human |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.059
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.059
|
Fly |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.059
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.059
|
Human |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.058
|
|
|
|
cellular response to triacyl bacterial lipopeptide
|
GO:0071727 |
2 |
0.058
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.058
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.058
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.058
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.058
|
Human |
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.058
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.057
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.057
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.057
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.057
|
Human Rat |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.056
|
Human |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.056
|
Human |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.056
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.056
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.056
|
Human |
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.055
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.055
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.055
|
Human |
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.055
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.055
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.054
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.054
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.053
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.053
|
Fly |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.053
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.052
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.052
|
Human |
|
|
serotonin secretion
|
GO:0001820 |
1 |
0.051
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.051
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.051
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.051
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.051
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.051
|
Human |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.051
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.051
|
Human |
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.050
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.049
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.049
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.048
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.048
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.048
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.047
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.046
|
Fly |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.046
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.046
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.046
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.045
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.045
|
Fly |
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.045
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.045
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.045
|
|
|
|
cellular response to diacyl bacterial lipopeptide
|
GO:0071726 |
2 |
0.045
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.045
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.044
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
3 |
0.044
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.044
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.044
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.044
|
Human |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.043
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.043
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.043
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.043
|
Fly |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.043
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.043
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.042
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.042
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.042
|
Fly |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.042
|
Human |
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.042
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.041
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.041
|
|
|
|
growth
|
GO:0040007 |
202 |
0.041
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.041
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.041
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.040
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.040
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.040
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.040
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.040
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
5 |
0.040
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.040
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.040
|
Human |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.040
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.039
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.039
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
1 |
0.039
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.039
|
Human |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.039
|
Human |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.038
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.038
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.038
|
Human |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.038
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.037
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.037
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.037
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.036
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.036
|
Human |
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.036
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.035
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.035
|
Human |
|
|
peptide transport
|
GO:0015833 |
74 |
0.035
|
Human |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.035
|
Human |
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.035
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.035
|
Human |
|
|
regulated secretory pathway
|
GO:0045055 |
20 |
0.035
|
Rat |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.035
|
Human |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.035
|
Fly |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.035
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.035
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.035
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.034
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.034
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.034
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.034
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.034
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.034
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.034
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.033
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.033
|
Rat |
|
|
response to diacyl bacterial lipopeptide
|
GO:0071724 |
2 |
0.033
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.033
|
Human |
|
|
arachidonic acid secretion
|
GO:0050482 |
7 |
0.033
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.033
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.033
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.032
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.032
|
Human |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.032
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.032
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.032
|
Human |
|
|
positive regulation of b cell activation
|
GO:0050871 |
17 |
0.032
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.032
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.031
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.031
|
|
|
|
cellular glucuronidation
|
GO:0052695 |
16 |
0.031
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.031
|
|
|
|
positive regulation of toll like receptor signaling pathway
|
GO:0034123 |
10 |
0.031
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.031
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.031
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.031
|
Human |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.031
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.031
|
Human |
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.031
|
Human |
|
|
response to wounding
|
GO:0009611 |
168 |
0.030
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
35 |
0.030
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.030
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.030
|
Human |
|
|
detection of bacterial lipoprotein
|
GO:0042494 |
3 |
0.030
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.030
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.030
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.030
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.030
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.030
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.030
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.029
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.029
|
Human |
|
|
negative regulation of mitochondrial depolarization
|
GO:0051902 |
2 |
0.029
|
Human |
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.029
|
Fly |
|
|
phototransduction
|
GO:0007602 |
3 |
0.029
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.029
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.029
|
Human |
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.029
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.029
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.029
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.028
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.028
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.028
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.028
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.028
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.028
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.028
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.028
|
Human Fly |
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.028
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.028
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.027
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.027
|
|
|
|
negative regulation of protein homooligomerization
|
GO:0032463 |
4 |
0.027
|
Human |
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.027
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.027
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.027
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.027
|
Human Rat |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.027
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
24 |
0.027
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.027
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.027
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.027
|
Human |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.027
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.027
|
Human |
|
|
protein import
|
GO:0017038 |
130 |
0.026
|
|
