|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
1.000
|
Human |
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
1.000
|
Fly |
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
1.000
|
Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.997
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.995
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.993
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.991
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.985
|
Fly |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.982
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.981
|
Fly |
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.976
|
Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.975
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.969
|
|
|
|
nephron tubule epithelial cell differentiation
|
GO:0072160 |
3 |
0.968
|
|
|
|
regulation of nephron tubule epithelial cell differentiation
|
GO:0072182 |
3 |
0.966
|
|
|
|
regulation of centrosome cycle
|
GO:0046605 |
15 |
0.965
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.959
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.956
|
Mouse Fly |
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.950
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.946
|
Fly |
|
|
protein import
|
GO:0017038 |
130 |
0.944
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.941
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.928
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.927
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.922
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.915
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.912
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.909
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.909
|
Worm |
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.906
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.903
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.889
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.883
|
Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.882
|
Fly |
|
|
dna conformation change
|
GO:0071103 |
113 |
0.879
|
Fly |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.878
|
Fly |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.877
|
Fly |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.876
|
Fly |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.871
|
Human Mouse |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.866
|
Fly |
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.857
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.855
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.854
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.852
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.849
|
Fly |
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.838
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.832
|
Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.831
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.817
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.815
|
Fly |
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.811
|
Fly |
|
|
regulation of centrosome duplication
|
GO:0010824 |
14 |
0.811
|
Fly |
|
|
negative regulation of tor signaling
|
GO:0032007 |
11 |
0.804
|
Fly |
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
4 |
0.799
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.798
|
Fly |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.796
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.792
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.791
|
Fly |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.786
|
Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.778
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.769
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.764
|
Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.763
|
Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.760
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.745
|
Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.744
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.744
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.742
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.741
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.738
|
|
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.737
|
Fly |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.737
|
Fly |
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.736
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.721
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.718
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.716
|
Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.712
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.698
|
Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.697
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.697
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.689
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.679
|
Fly |
|
|
centrosome organization
|
GO:0051297 |
58 |
0.671
|
Fly |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.667
|
Fly |
|
|
associative learning
|
GO:0008306 |
1 |
0.663
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.658
|
Worm Fly |
|
|
nuclear import
|
GO:0051170 |
106 |
0.652
|
Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.651
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.651
|
Fly |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.647
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.640
|
Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.635
|
Fly |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.632
|
Fly |
|
|
dna packaging
|
GO:0006323 |
77 |
0.613
|
Fly |
|
|
protein targeting
|
GO:0006605 |
187 |
0.612
|
Fly |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.605
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.604
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.599
|
|
|
|
canonical wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
|
GO:0044334 |
2 |
0.599
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.598
|
Fly |
|
|
protein destabilization
|
GO:0031648 |
12 |
0.587
|
|
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
1 |
0.586
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
17 |
0.583
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.583
|
Fly |
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.582
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.581
|
Fly |
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.570
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.566
|
Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.556
|
Fly |
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.552
|
Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.545
|
Fly |
|
|
pharynx development
|
GO:0060465 |
1 |
0.543
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.539
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.536
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.533
|
Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.532
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.517
|
Fly |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.516
|
Fly |
|
|
lung associated mesenchyme development
|
GO:0060484 |
1 |
0.515
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.513
|
Fly |
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.512
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.510
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.507
|
Worm |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.504
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.501
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.496
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.493
|
Fly |
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.488
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.480
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.469
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.460
|
Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.459
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.457
|
|
|
|
positive regulation of endothelial cell differentiation
|
GO:0045603 |
2 |
0.454
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.451
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.436
|
Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.432
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.432
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.431
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.430
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.423
|
Fly |
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
2 |
0.421
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.418
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.412
|
|
|
|
positive regulation of keratinocyte proliferation
|
GO:0010838 |
4 |
0.411
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.400
|
|
|
|
mating
|
GO:0007618 |
1 |
0.397
|
|
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.395
|
Fly |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.392
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.390
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.380
|
Mouse |
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
6 |
0.379
|
Fly |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.377
|
Fly |
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.376
|
Fly |
|
|
nephron tubule formation
|
GO:0072079 |
1 |
0.374
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.372
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.359
|
Fly |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.359
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.358
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.357
|
Fly |
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.354
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.353
|
Fly |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.352
|
Mouse Fly |
|
|
spindle organization
|
GO:0007051 |
53 |
0.351
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
3 |
0.349
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.346
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.342
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.335
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.328
|
Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.325
|
Worm |
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.324
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.321
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.316
|
|
|
|
negative regulation of heart induction by canonical wnt signaling pathway
|
GO:0003136 |
1 |
0.315
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.314
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.312
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.310
|
Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.309
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.307
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.306
|
Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.303
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.297
|
Fly |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.295
|
Fly |
|
|
positive regulation of proteoglycan biosynthetic process
|
GO:1902730 |
3 |
0.292
|
|
|
|
negative regulation of catagen
|
GO:0051796 |
1 |
0.289
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.287
|
Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.285
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.284
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.283
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.283
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.279
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.278
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.276
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.276
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.274
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.270
|
Fly |
|
|
cell differentiation involved in kidney development
|
GO:0061005 |
9 |
0.270
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.267
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.267
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.266
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.264
|
Worm Fly |
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.264
|
Fly |
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.263
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.258
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.256
|
Fly |
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.256
|
Fly |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.254
|
Fly |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.254
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.251
|
Worm Fly |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.249
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.247
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.247
|
|
|
|
regulation of myelination
|
GO:0031641 |
1 |
0.246
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.246
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.245
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.245
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.244
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.243
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.243
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.243
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.242
|
Fly |
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.242
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.241
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.240
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.239
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.239
|
Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.238
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.236
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.235
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.235
|
Worm Fly |
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.234
|
Fly |
|
|
neurological system process
|
GO:0050877 |
163 |
0.233
|
Fly |
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.232
|
Fly |
|
|
regulation of circadian rhythm
|
GO:0042752 |
11 |
0.231
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.229
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.228
|
|
|
|
positive regulation of glycoprotein metabolic process
|
GO:1903020 |
8 |
0.227
|
|
|
|
system process
|
GO:0003008 |
349 |
0.227
|
Fly |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.226
|
|
|
|
centriole replication
|
GO:0007099 |
13 |
0.224
|
Fly |
|
|
action potential
|
GO:0001508 |
34 |
0.223
|
|
|
|
heart field specification
|
GO:0003128 |
2 |
0.222
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.222
|
|
|
|
cell competition in a multicellular organism
|
GO:0035212 |
1 |
0.219
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.219
|
Worm Fly |
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.219
|
|
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.219
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.212
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.212
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.210
|
Worm Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.210
|
Fly |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.209
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.209
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.208
|
Fly |
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.208
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.206
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.204
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.203
|
|
|
|
cardiac muscle cell cardiac muscle cell adhesion
|
GO:0086042 |
1 |
0.202
|
|
|
|
metanephric nephron epithelium development
|
GO:0072243 |
4 |
0.196
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.196
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.196
|
|
|
|
centromere complex assembly
|
GO:0034508 |
10 |
0.192
|
|
|
|
negative regulation of catenin import into nucleus
|
GO:0035414 |
7 |
0.191
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.191
|
Fly |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.189
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.189
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.187
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.184
|
Fly |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.183
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.183
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.183
|
Fly |
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.182
|
|
|
|
autonomic nervous system development
|
GO:0048483 |
1 |
0.181
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.176
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.170
|
Worm Fly |
|
|
regulation of melanosome transport
|
GO:1902908 |
1 |
0.170
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.169
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.168
|
Mouse |
|
|
somitogenesis
|
GO:0001756 |
2 |
0.166
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.165
|
|
|
|
chromosome condensation
|
GO:0030261 |
15 |
0.165
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.165
|
Mouse |
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.165
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.164
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.163
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.162
|
|
|
|
growth
|
GO:0040007 |
202 |
0.162
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.160
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.159
|
|
|
|
regulation of granulocyte differentiation
|
GO:0030852 |
11 |
0.159
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.158
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.157
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.156
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.155
|
Mouse Fly |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.154
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.154
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.153
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.152
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.152
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.150
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.149
|
|
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
15 |
0.149
|
|
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.148
|
Fly |
|
|
negative regulation of chondrocyte differentiation
|
GO:0032331 |
5 |
0.147
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
10 |
0.145
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.145
|
Fly |
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.143
|
Fly |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.143
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.142
|
Fly |
|
|
kidney development
|
GO:0001822 |
53 |
0.138
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.137
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.137
|
|
|
|
positive regulation of embryonic development
|
GO:0040019 |
6 |
0.136
|
|
|
|
centriole assembly
|
GO:0098534 |
14 |
0.135
|
Fly |
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.133
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.131
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.128
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.128
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.128
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.126
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.126
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.125
|
Fly |
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.123
|
Fly |
|
|
protein neddylation
|
GO:0045116 |
7 |
0.123
|
|
|
|
tongue development
|
GO:0043586 |
1 |
0.122
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.122
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.122
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.121
|
|
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.120
|
Fly |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.120
|
Fly |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.118
|
Fly |
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.118
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.117
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.117
|
Worm Fly |
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.116
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.116
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.115
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.114
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.113
|
Fly |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.112
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.111
|
Fly |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.111
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.110
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.110
|
Mouse |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.109
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.108
|
Worm |
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.108
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.106
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.106
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.105
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.105
|
Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.105
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.105
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.104
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.103
|
Worm |
|
|
regulation of triglyceride metabolic process
|
GO:0090207 |
11 |
0.103
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.103
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.102
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.102
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.101
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.101
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.101
|
Worm Fly |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.100
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.100
|
|
|
|
positive regulation of telomerase activity
|
GO:0051973 |
4 |
0.100
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.099
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.099
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.099
|
Fly |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.099
|
Mouse |
|
|
response to virus
|
GO:0009615 |
126 |
0.099
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.097
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.097
|
|
|
|
cytoplasmic sequestering of nf kappab
|
GO:0007253 |
7 |
0.097
|
Fly |
|
|
snare complex assembly
|
GO:0035493 |
3 |
0.096
|
|
|
|
glucan metabolic process
|
GO:0044042 |
22 |
0.095
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.095
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.095
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.095
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.094
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.094
|
Fly |
|
|
negative regulation of cardioblast cell fate specification
|
GO:0009997 |
1 |
0.093
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.092
|
|
|
|
aging
|
GO:0007568 |
66 |
0.091
|
Worm |
|
|
cell development
|
GO:0048468 |
328 |
0.090
|
Worm Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.090
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
15 |
0.090
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.089
|
|
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.089
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.089
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.089
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.089
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.089
|
|
|
|
myelination
|
GO:0042552 |
6 |
0.088
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.088
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.088
|
Mouse |
|
|
regulation of keratinocyte proliferation
|
GO:0010837 |
11 |
0.088
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.087
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.087
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.086
|
|
|
|
cell differentiation involved in metanephros development
|
GO:0072202 |
3 |
0.086
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.086
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.086
|
Worm |
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.085
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.085
|
|
|
|
regulation of cell diameter
|
GO:0060305 |
1 |
0.085
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.085
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.084
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.083
|
|
|
|
embryonic skeletal joint morphogenesis
|
GO:0060272 |
2 |
0.083
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.082
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.081
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.081
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.080
|
|
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.080
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.080
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.080
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.079
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.079
|
Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.079
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.079
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.079
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.078
|
Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.078
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.077
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.077
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.077
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
17 |
0.077
|
Fly |
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.077
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.076
|
|
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
3 |
0.076
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.076
|
|
|
|
heparan sulfate proteoglycan metabolic process
|
GO:0030201 |
12 |
0.075
|
|
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
7 |
0.075
|
|
|
|
establishment of endothelial blood brain barrier
|
GO:0014045 |
1 |
0.074
|
|
|
|
positive regulation of cell proliferation in bone marrow
|
GO:0071864 |
1 |
0.074
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.073
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.073
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.072
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.072
|
Mouse Fly |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.072
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.072
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.072
|
Fly |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.072
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.071
|
|
|
|
establishment of blood brain barrier
|
GO:0060856 |
1 |
0.071
|
|
|
|
renal vesicle development
|
GO:0072087 |
4 |
0.071
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.071
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.070
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.069
|
Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.069
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.068
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.068
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.067
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.067
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.067
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.066
|
Mouse |
|
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.066
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.066
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.065
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.065
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.065
|
Fly |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.064
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.064
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.063
|
Fly |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.063
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.062
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.062
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.062
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.062
|
|
|
|
catagen
|
GO:0042637 |
3 |
0.062
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.062
|
Worm Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.062
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.061
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.061
|
|
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
0.061
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.060
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.060
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.060
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.060
|
Fly |
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
2 |
0.060
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.059
|
Fly |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.059
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.059
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.058
|
Fly |
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.058
|
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.058
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.057
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.057
|
Fly |
|
|
glutamate metabolic process
|
GO:0006536 |
10 |
0.057
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.056
|
|
