|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
1.000
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
1.000
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
1.000
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
1.000
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
1.000
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
1.000
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
1.000
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
1.000
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
1.000
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
1.000
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.999
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.999
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.999
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.998
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
13 |
0.998
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.998
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.996
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.995
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.994
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.993
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.990
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.986
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.984
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.982
|
|
|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
0.978
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.976
|
|
|
|
regulation of ruffle assembly
|
GO:1900027 |
8 |
0.974
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.973
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.969
|
|
|
|
positive regulation of ruffle assembly
|
GO:1900029 |
4 |
0.966
|
|
|
|
growth
|
GO:0040007 |
202 |
0.966
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
5 |
0.962
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.961
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.960
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.958
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.956
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.953
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.950
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.949
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.948
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
28 |
0.946
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.945
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.944
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.941
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.940
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.937
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.934
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.929
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.929
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.928
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.926
|
|
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.918
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.918
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.913
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.911
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.910
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.908
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.908
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.905
|
|
|
|
positive regulation of lyase activity
|
GO:0051349 |
16 |
0.902
|
|
|
|
membrane raft localization
|
GO:0051665 |
1 |
0.900
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.895
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.890
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.880
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.879
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.877
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.876
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.874
|
|
|
|
sa node cell action potential
|
GO:0086015 |
1 |
0.874
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.873
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.871
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.871
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.867
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.866
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.857
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.854
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.853
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.848
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.848
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.846
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.846
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.841
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.833
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.826
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.826
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.822
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.811
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.809
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.807
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.805
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.802
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.801
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.798
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.798
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.794
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.790
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.786
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.785
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.783
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.779
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.778
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.771
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.770
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.768
|
|
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.767
|
|
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.760
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.758
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.757
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.755
|
|
|
|
regulation of filopodium assembly
|
GO:0051489 |
13 |
0.755
|
|
|
|
membrane repolarization during sa node cell action potential
|
GO:0086052 |
1 |
0.752
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.746
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.739
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.739
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.738
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.736
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.736
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.735
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.731
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.731
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.728
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.726
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.720
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.719
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.716
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.715
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.715
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.711
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.711
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.709
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.705
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.704
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.700
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
29 |
0.690
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.689
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.688
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.680
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.679
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.676
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.674
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.673
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.673
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.666
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.658
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.657
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.655
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.653
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.647
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.642
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.636
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.634
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.632
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.630
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.629
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.628
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.627
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.627
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.624
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.622
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.621
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.619
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.618
|
|
|
|
regulation of calcium ion transmembrane transport
|
GO:1903169 |
28 |
0.613
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.612
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.611
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.610
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.610
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.605
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.592
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.580
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.572
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.571
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.567
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.567
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.565
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.560
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.559
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.559
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.557
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.541
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.540
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.540
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.539
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.538
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.533
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.530
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.527
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.519
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.518
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
33 |
0.513
|
|
|
|
localization within membrane
|
GO:0051668 |
14 |
0.509
|
|
|
|
negative regulation of ras gtpase activity
|
GO:0034261 |
6 |
0.507
|
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.505
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.505
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.503
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.499
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.496
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.495
|
|
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.494
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
3 |
0.493
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.492
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.492
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.491
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.488
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.485
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.483
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.477
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.476
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.473
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.473
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.472
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.466
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.461
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.460
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.454
|
|
|
|
negative regulation of nucleotide catabolic process
|
GO:0030812 |
16 |
0.453
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.453
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.452
|
|
|
|
epithelial fluid transport
|
GO:0042045 |
1 |
0.452
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.451
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.449
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.443
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.438
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.437
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.437
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.436
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.433
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.432
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.430
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.430
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.427
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.419
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.414
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.412
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
14 |
0.409
|
|
|
|
positive regulation of actin cytoskeleton reorganization
|
GO:2000251 |
9 |
0.407
|
|
|
|
response to nutrient
|
GO:0007584 |
20 |
0.404
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.401
|
|
|
|
mirna metabolic process
|
GO:0010586 |
10 |
0.400
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.395
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.374
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.373
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.369
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.369
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.366
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.362
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.361
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.353
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.352
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.350
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.345
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.341
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.340
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.340
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.330
|
|
|
|
regulation of heart rate by cardiac conduction
|
GO:0086091 |
19 |
0.330
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.328
|
|
|
|
regulation of mirna metabolic process
|
GO:2000628 |
5 |
0.327
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.327
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.325
|
|
|
|
sa node cell to atrial cardiac muscle cell signalling
|
GO:0086018 |
1 |
0.324
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.321
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.320
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.317
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.314
|
|
|
|
system process
|
GO:0003008 |
349 |
0.314
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.312
|
|
|
|
regulation of potassium ion export
|
GO:1902302 |
1 |
0.310
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.310
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.309
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.309
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.308
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.303
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.302
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.298
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
28 |
0.297
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.296
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.295
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.295
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.292
|
|
|
|
sa node cell to atrial cardiac muscle cell communication
|
GO:0086070 |
3 |
0.289
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.286
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.286
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.283
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.282
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.282
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.278
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.277
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.276
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.274
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.269
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.269
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.268
|
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.265
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.261
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.259
|
|
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
28 |
0.259
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.258
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.256
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.254
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.253
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.252
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.249
|
|
|
|
head development
|
GO:0060322 |
108 |
0.248
|
|
|
|
negative regulation of nucleoside metabolic process
|
GO:0045978 |
18 |
0.248
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.247
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.245
|
|
|
|
golgi vesicle fusion to target membrane
|
GO:0048210 |
2 |
0.244
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.244
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.243
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.242
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.238
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.235
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.230
|
|
|
|
membrane repolarization during action potential
|
GO:0086011 |
8 |
0.229
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.226
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.221
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.216
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.215
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.215
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.214
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.213
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.212
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.211
|
|
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
5 |
0.211
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.209
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.208
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.205
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.204
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.201
|
|
|
|
ruffle assembly
|
GO:0097178 |
10 |
0.199
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.193
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.191
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.189
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.188
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.188
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.187
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.180
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.178
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.177
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.175
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.174
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.173
|
|
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.169
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.168
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.168
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.167
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.166
|
|
|
|
positive regulation of filopodium assembly
|
GO:0051491 |
7 |
0.166
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.162
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.162
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.160
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.160
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.160
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.159
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.154
|
|
|
|
negative regulation of calcium ion transport
|
GO:0051926 |
19 |
0.154
|
|
|
|
negative regulation of gtp catabolic process
|
GO:0033125 |
11 |
0.154
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.152
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.151
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.151
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.150
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.149
|
|
|
|
aging
|
GO:0007568 |
66 |
0.148
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.148
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.148
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.148
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.145
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.142
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.142
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.141
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.140
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.140
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.139
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.137
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.136
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
37 |
0.135
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.133
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.132
|
|
|
|
cellular protein complex localization
|
GO:0034629 |
8 |
0.132
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.130
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.128
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.127
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.127
|
|
|
|
negative regulation of gtpase activity
|
GO:0034260 |
11 |
0.126
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.125
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.125
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.124
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.121
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.121
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.120
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.118
|
|
|
|
ruffle organization
|
GO:0031529 |
18 |
0.118
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.117
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
18 |
0.117
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.113
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.113
|
|
|
|
cellular response to corticotropin releasing hormone stimulus
|
GO:0071376 |
1 |
0.111
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.110
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.110
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.110
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.110
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.109
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.108
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.105
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
7 |
0.104
|
|
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.104
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.103
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.103
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.102
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.102
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.102
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.101
|
|
|
|
fluid transport
|
GO:0042044 |
6 |
0.101
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.100
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.098
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.098
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.096
|
|
|
|
membrane depolarization
|
GO:0051899 |
26 |
0.096
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.095
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.095
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.094
|
|
|
|
negative regulation of ion transmembrane transporter activity
|
GO:0032413 |
19 |
0.093
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.092
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.091
|
|
|
|
cardiac conduction
|
GO:0061337 |
23 |
0.090
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.090
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.089
|
|
|
|
negative regulation of potassium ion export
|
GO:1902303 |
1 |
0.088
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.087
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.087
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.087
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.086
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.086
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.086
|
|
|
|
detection of visible light
|
GO:0009584 |
11 |
0.085
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.084
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.084
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.084
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.083
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.083
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.083
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.083
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.082
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.082
|
|
|
|
positive regulation of mirna metabolic process
|
GO:2000630 |
4 |
0.082
|
|
|
|
memory
|
GO:0007613 |
3 |
0.082
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.081
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.079
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.079
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.079
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.078
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.078
|
|
|
|
visual perception
|
GO:0007601 |
27 |
0.077
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.076
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.076
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.075
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.075
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.075
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.074
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.074
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.074
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.073
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.071
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.071
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.071
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.071
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.070
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.070
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.070
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.069
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.069
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.068
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.068
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.068
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.068
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.068
|
|
|
|
negative regulation of transporter activity
|
GO:0032410 |
25 |
0.067
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.067
|
|
|
|
negative regulation of purine nucleotide catabolic process
|
GO:0033122 |
16 |
0.067
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.067
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.067
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.066
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.066
|
|
|
|
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway
|
GO:0010579 |
5 |
0.065
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.065
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.065
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.064
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.064
|
|
