|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
16 |
1.000
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
1.000
|
Mouse |
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.998
|
|
|
mating
|
GO:0007618 |
1 |
0.997
|
Fly |
|
startle response
|
GO:0001964 |
3 |
0.995
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.994
|
Human |
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.993
|
Mouse |
|
regulation of relaxation of cardiac muscle
|
GO:1901897 |
2 |
0.990
|
Human |
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.987
|
Human |
|
memory
|
GO:0007613 |
3 |
0.986
|
Fly |
|
synaptic transmission cholinergic
|
GO:0007271 |
2 |
0.982
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.978
|
Human |
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.972
|
Human |
|
cation transport
|
GO:0006812 |
331 |
0.965
|
Human Mouse |
|
transmembrane transport
|
GO:0055085 |
399 |
0.964
|
Human |
|
synaptic transmission
|
GO:0007268 |
61 |
0.963
|
Mouse Fly |
|
positive regulation of organic acid transport
|
GO:0032892 |
3 |
0.955
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.950
|
Human |
|
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway
|
GO:0007196 |
4 |
0.936
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.923
|
Human |
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.908
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.903
|
Human Mouse |
|
amino acid transport
|
GO:0006865 |
28 |
0.889
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.889
|
Human |
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.884
|
Fly |
|
sodium ion transport
|
GO:0006814 |
61 |
0.881
|
Human |
|
glutamate receptor signaling pathway
|
GO:0007215 |
23 |
0.872
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.854
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.849
|
Mouse |
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.847
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.845
|
Human Mouse |
|
long term memory
|
GO:0007616 |
2 |
0.843
|
Fly |
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.838
|
Human |
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.838
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.838
|
Human |
|
negative regulation of transport
|
GO:0051051 |
176 |
0.826
|
Human |
|
regulation of ion transport
|
GO:0043269 |
189 |
0.821
|
Human Mouse |
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.819
|
Mouse |
|
anion transport
|
GO:0006820 |
161 |
0.800
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.792
|
Human |
|
potassium ion transport
|
GO:0006813 |
62 |
0.780
|
|
|
relaxation of cardiac muscle
|
GO:0055119 |
5 |
0.776
|
Human |
|
organic anion transport
|
GO:0015711 |
103 |
0.769
|
|
|
behavioral fear response
|
GO:0001662 |
0 |
0.767
|
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
14 |
0.755
|
Human |
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.732
|
Human |
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.727
|
Human Mouse |
|
positive regulation of amine transport
|
GO:0051954 |
2 |
0.726
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.715
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.694
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.676
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.648
|
Mouse |
|
cell cell signaling
|
GO:0007267 |
155 |
0.628
|
Mouse Fly |
|
regulation of amine transport
|
GO:0051952 |
5 |
0.621
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.611
|
Fly |
|
response to magnesium ion
|
GO:0032026 |
3 |
0.593
|
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.584
|
Human |
|
actin filament based process
|
GO:0030029 |
224 |
0.557
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.557
|
Human Mouse |
|
positive regulation of muscle hypertrophy
|
GO:0014742 |
6 |
0.549
|
Human |
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.540
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.537
|
|
|
fear response
|
GO:0042596 |
0 |
0.533
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.531
|
|
|
regulation of anion transport
|
GO:0044070 |
25 |
0.530
|
|
|
associative learning
|
GO:0008306 |
1 |
0.526
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.524
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.514
|
Mouse |
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.499
|
Human Worm |
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.493
|
Human |
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
1 |
0.480
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.477
|
Human |
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.471
|
Human |
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.448
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.441
|
Mouse |
|
positive regulation of potassium ion transport
|
GO:0043268 |
15 |
0.435
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.423
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.421
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.419
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.407
|
|
|
system process
|
GO:0003008 |
349 |
0.404
|
Human Fly |
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.403
|
|
|
regulation of relaxation of muscle
|
GO:1901077 |
3 |
0.366
|
Human |
|
muscle hypertrophy
|
GO:0014896 |
14 |
0.362
|
Human |
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.349
|
Human |
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.349
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.344
|
Human |
|
response to manganese ion
|
GO:0010042 |
2 |
0.343
|
|
|
negative regulation of transporter activity
|
GO:0032410 |
25 |
0.340
|
Human |
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.340
|
Human |
|
cellular response to manganese ion
|
GO:0071287 |
1 |
0.339
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.337
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.337
|
|
|
relaxation of muscle
|
GO:0090075 |
7 |
0.329
|
Human |
|
protein localization to membrane
|
GO:0072657 |
160 |
0.320
|
|
|
negative regulation of ion transmembrane transporter activity
|
GO:0032413 |
19 |
0.303
|
Human |
|
response to alkaloid
|
GO:0043279 |
20 |
0.295
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
22 |
0.295
|
|
|
neuromuscular process
|
GO:0050905 |
15 |
0.289
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.289
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.289
|
Mouse |
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.287
|
Human |
|
cerebral cortex development
|
GO:0021987 |
10 |
0.287
|
|
|
response to electrical stimulus
|
GO:0051602 |
1 |
0.273
|
|
|
regulation of dendritic spine development
|
GO:0060998 |
5 |
0.268
|
|
|
behavior
|
GO:0007610 |
112 |
0.268
|
Fly |
|
single organism membrane organization
|
GO:0044802 |
268 |
0.264
|
Mouse |
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.257
|
Mouse |
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.251
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
43 |
0.250
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.250
|
Fly |
|
negative regulation of g protein coupled receptor protein signaling pathway
|
GO:0045744 |
18 |
0.247
|
|
|
secretion
|
GO:0046903 |
254 |
0.246
|
Mouse |
|
hippocampus development
|
GO:0021766 |
1 |
0.246
|
|
|
defense response
|
GO:0006952 |
315 |
0.242
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.241
|
Human |
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.241
|
Human Worm |
|
response to cocaine
|
GO:0042220 |
1 |
0.237
|
|
|
regulation of muscle adaptation
|
GO:0043502 |
10 |
0.235
|
Human |
|
acid secretion
|
GO:0046717 |
12 |
0.234
|
|
|
regulation of organic acid transport
|
GO:0032890 |
8 |
0.233
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.230
|
Mouse |
|
membrane depolarization
|
GO:0051899 |
26 |
0.223
|
Human |
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.215
|
Human |
|
single organism behavior
|
GO:0044708 |
28 |
0.213
|
Fly |
|
female gamete generation
|
GO:0007292 |
2 |
0.206
|
Fly |
|
response to calcium ion
|
GO:0051592 |
46 |
0.203
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.201
|
Mouse |
|
neuromuscular process controlling balance
|
GO:0050885 |
7 |
0.197
|
|
|
taxis
|
GO:0042330 |
157 |
0.193
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.190
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.190
|
Fly |
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.188
|
|
|
cognition
|
GO:0050890 |
43 |
0.187
|
Fly |
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.186
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.186
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.184
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.184
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.184
|
Human |
|
dephosphorylation
|
GO:0016311 |
209 |
0.179
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.177
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.175
|
Fly |
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.173
|
|
|
growth
|
GO:0040007 |
202 |
0.173
|
Fly |
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.171
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.169
|
|
|
cellular response to dsrna
|
GO:0071359 |
19 |
0.165
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.163
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.162
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.160
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.159
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.158
|
Worm |
|
regulation of secretion
|
GO:0051046 |
194 |
0.154
|
Mouse |
|
positive regulation of cardiac muscle hypertrophy
|
GO:0010613 |
6 |
0.154
|
Human |
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.151
|
Mouse Worm |
|
cation homeostasis
|
GO:0055080 |
189 |
0.150
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.149
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.148
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.145
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.143
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.139
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.137
|
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.136
|
Human |
|
rhythmic behavior
|
GO:0007622 |
2 |
0.135
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.132
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.130
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.130
|
Mouse Worm |
|
neuron neuron synaptic transmission
|
GO:0007270 |
6 |
0.129
|
|
|
fertilization
|
GO:0009566 |
12 |
0.129
|
|
|
positive regulation of dendritic spine development
|
GO:0060999 |
2 |
0.128
|
|
|
regulation of synapse assembly
|
GO:0051963 |
5 |
0.128
|
Fly |
|
detection of stimulus
|
GO:0051606 |
85 |
0.127
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.124
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.123
|
Mouse |
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.122
|
Human |
|
dicarboxylic acid transport
|
GO:0006835 |
13 |
0.122
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.121
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.119
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.119
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.116
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.115
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.113
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.109
|
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
1 |
0.106
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.105
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.104
|
Worm |
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.103
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.102
|
Mouse |
|
organelle fission
|
GO:0048285 |
149 |
0.101
|
Worm |
|
response to starvation
|
GO:0042594 |
59 |
0.101
|
|
|
cell development
|
GO:0048468 |
328 |
0.101
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.101
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.101
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.100
|
Human Mouse |
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.098
|
Human |
|
cellular response to starvation
|
GO:0009267 |
58 |
0.096
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.096
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.095
|
Fly |
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.095
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.095
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.093
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.093
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.090
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.090
|
Fly |
|
response to other organism
|
GO:0051707 |
261 |
0.089
|
|
|
dendritic spine organization
|
GO:0097061 |
4 |
0.089
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.088
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.087
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.087
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.087
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.086
|
|
|
g protein coupled glutamate receptor signaling pathway
|
GO:0007216 |
8 |
0.085
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.084
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.082
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.081
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.081
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.080
|
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.080
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.079
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.078
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.078
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.077
|
Mouse |
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.077
|
Mouse |
|
regulation of filopodium assembly
|
GO:0051489 |
13 |
0.076
|
Fly |
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.075
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.075
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.075
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.074
|
|
|
pallium development
|
GO:0021543 |
10 |
0.074
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.074
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.074
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.073
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.072
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.072
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.072
|
|
|
neuron development
|
GO:0048666 |
113 |
0.071
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.070
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.069
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.069
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.068
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.068
|
|
|
cell division
|
GO:0051301 |
168 |
0.068
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.068
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.067
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.067
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.067
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.066
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.066
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.065
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.065
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.065
|
|
|
cell activation
|
GO:0001775 |
213 |
0.065
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.064
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.064
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.064
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.064
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.063
|
Mouse |
|
biological adhesion
|
GO:0022610 |
331 |
0.063
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.062
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.062
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.061
|
|
|
response to dsrna
|
GO:0043331 |
25 |
0.060
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.060
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.060
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.060
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.059
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.058
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.058
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.057
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.057
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.057
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.057
|
Fly |
|
opioid receptor signaling pathway
|
GO:0038003 |
4 |
0.057
|
|
|
single fertilization
|
GO:0007338 |
11 |
0.056
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.056
|
Human |
|
synapse assembly
|
GO:0007416 |
8 |
0.056
|
Fly |
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.055
|
Mouse |
|
regulation of atrial cardiac muscle cell membrane repolarization
|
GO:0060372 |
4 |
0.055
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.054
|
Human |
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.054
|
Fly |
|
visual learning
|
GO:0008542 |
1 |
0.053
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.053
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.053
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.052
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.051
|
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.051
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.051
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.051
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.051
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.051
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.050
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.048
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.048
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.048
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.048
|
Mouse |
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.048
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.047
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.047
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.047
|
|
|
protein kinase a signaling
|
GO:0010737 |
9 |
0.047
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.046
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.046
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.046
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.046
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
40 |
0.046
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.045
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.045
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.045
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.044
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.044
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.043
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.043
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.042
|
Mouse |
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.042
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.042
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.041
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.041
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.041
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.040
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.040
|
|
|
response to cadmium ion
|
GO:0046686 |
10 |
0.040
|
|
|
protein localization to synapse
|
GO:0035418 |
2 |
0.040
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.039
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.039
|
Human |
|
positive regulation of transporter activity
|
GO:0032411 |
32 |
0.039
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.039
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.039
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.039
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.038
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
29 |
0.038
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.037
|
Fly |
|
brain development
|
GO:0007420 |
97 |
0.037
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.036
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.036
|
|
|
response to drug
|
GO:0042493 |
81 |
0.036
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.036
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.036
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.036
|
|
|
regulation of synapse organization
|
GO:0050807 |
7 |
0.035
|
Fly |
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.035
|
|
|
dendritic spine development
|
GO:0060996 |
6 |
0.035
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.035
|
|
|
desensitization of g protein coupled receptor protein signaling pathway
|
GO:0002029 |
7 |
0.034
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.034
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.034
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.034
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.034
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.034
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.034
|
|
|
membrane hyperpolarization
|
GO:0060081 |
1 |
0.033
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.033
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.033
|
|
|
response to amino acid
|
GO:0043200 |
14 |
0.033
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.033
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.033
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.032
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.032
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.032
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.032
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.032
|
|
|
neuron cell cell adhesion
|
GO:0007158 |
1 |
0.032
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.032
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.032
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.032
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.032
|
|
|
segmentation
|
GO:0035282 |
4 |
0.031
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.030
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.030
|
|
|
signal release
|
GO:0023061 |
70 |
0.030
|
Mouse |
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.030
|
|
|
embryo development
|
GO:0009790 |
123 |
0.030
|
|
|
positive regulation of meiosis
|
GO:0045836 |
2 |
0.029
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.029
|
|
|
regulation of cardiac muscle hypertrophy
|
GO:0010611 |
10 |
0.029
|
Human |
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.029
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.028
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.028
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.028
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.028
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
12 |
0.028
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.028
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.027
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.027
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.027
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.027
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.027
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.027
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.027
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.027
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.027
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.026
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.026
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.026
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.026
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.026
|
Fly |
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.026
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.026
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.026
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.026
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.025
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.025
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.025
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.025
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.024
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.024
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.024
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
28 |
0.024
|
|
|
vocalization behavior
|
GO:0071625 |
11 |
0.024
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.024
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.024
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.024
|
|
|
adaptation of signaling pathway
|
GO:0023058 |
7 |
0.024
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.024
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.024
|
|
|
negative regulation of cytosolic calcium ion concentration
|
GO:0051481 |
1 |
0.024
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.024
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.024
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.023
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.023
|
|
|
reproduction
|
GO:0000003 |
63 |
0.023
|
Fly |
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.023
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.023
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.023
|
|
|
anion transmembrane transport
|
GO:0098656 |
76 |
0.023
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.023
|
|
|
serotonin transport
|
GO:0006837 |
3 |
0.023
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.023
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.023
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.023
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.023
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.023
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.023
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.022
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.022
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.022
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.022
|
|
|
dopamine uptake involved in synaptic transmission
|
GO:0051583 |
4 |
0.022
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.022
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.022
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.022
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.022
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.022
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.022
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.022
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.021
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.021
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.021
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.021
|
|
|
negative adaptation of signaling pathway
|
GO:0022401 |
7 |
0.021
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.021
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.021
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.021
|
|
|
head development
|
GO:0060322 |
108 |
0.021
|
|
|
potassium ion export
|
GO:0071435 |
9 |
0.021
|
|
|
urate transport
|
GO:0015747 |
3 |
0.021
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.020
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.020
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.020
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.020
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.020
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.020
|
|
|
l amino acid import
|
GO:0043092 |
4 |
0.020
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.020
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.020
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.020
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.020
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.020
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.020
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.020
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.020
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.020
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.020
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.020
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.020
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.020
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.020
|
Human |
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.019
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.019
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.019
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.019
|
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
1 |
0.019
|
|