|
|
cellular modified amino acid catabolic process
|
GO:0042219 |
4 |
1.000
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.993
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.988
|
Human Mouse |
|
|
alpha amino acid catabolic process
|
GO:1901606 |
26 |
0.978
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.969
|
Mouse |
|
|
negative regulation of humoral immune response
|
GO:0002921 |
7 |
0.964
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.955
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.954
|
Human Mouse |
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.950
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.950
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.948
|
|
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
7 |
0.946
|
Human |
|
|
trail activated apoptotic signaling pathway
|
GO:0036462 |
4 |
0.939
|
Human |
|
|
carboxylic acid catabolic process
|
GO:0046395 |
71 |
0.929
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.921
|
Human Mouse |
|
|
protein processing
|
GO:0016485 |
226 |
0.921
|
Human Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.917
|
Human |
|
|
cellular amino acid catabolic process
|
GO:0009063 |
31 |
0.903
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.902
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.891
|
Human Mouse |
|
|
limbic system development
|
GO:0021761 |
3 |
0.880
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.874
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.869
|
Human Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.867
|
Human Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.857
|
Human Zebrafish Mouse Rat |
|
|
protein maturation
|
GO:0051604 |
233 |
0.839
|
Human Mouse |
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
11 |
0.839
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.819
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.812
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.811
|
Human Zebrafish Mouse Rat |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.785
|
Human Mouse |
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.767
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
7 |
0.748
|
Rat |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.747
|
Mouse |
|
|
tube closure
|
GO:0060606 |
3 |
0.742
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.739
|
Mouse Rat |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.730
|
Human |
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.729
|
Human |
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.720
|
Human |
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.717
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.713
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.710
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.693
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.676
|
Human |
|
|
triglyceride homeostasis
|
GO:0070328 |
14 |
0.675
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.670
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.658
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.646
|
Human Mouse |
|
|
acylglycerol homeostasis
|
GO:0055090 |
14 |
0.639
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.632
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.631
|
Human Mouse |
|
|
response to radiation
|
GO:0009314 |
151 |
0.623
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.620
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.616
|
|
|
|
activated t cell proliferation
|
GO:0050798 |
13 |
0.615
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.612
|
Human |
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.602
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.593
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.584
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.582
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.576
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.574
|
Human Mouse |
|
|
neural tube closure
|
GO:0001843 |
3 |
0.570
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.561
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.560
|
Human |
|
|
response to cobalt ion
|
GO:0032025 |
1 |
0.550
|
Rat |
|
|
forebrain development
|
GO:0030900 |
26 |
0.536
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.528
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.527
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.509
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.499
|
Human |
|
|
spermatid development
|
GO:0007286 |
4 |
0.482
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.478
|
|
|
|
cellular response to antibiotic
|
GO:0071236 |
1 |
0.477
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.477
|
Human |
|
|
cellular response to xenobiotic stimulus
|
GO:0071466 |
29 |
0.471
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.471
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.465
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.463
|
|
|
|
response to antibiotic
|
GO:0046677 |
15 |
0.460
|
Rat |
|
|
pallium development
|
GO:0021543 |
10 |
0.450
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.450
|
|
|
|
apoptotic dna fragmentation
|
GO:0006309 |
6 |
0.450
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.447
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.446
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.445
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.431
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.418
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.403
|
Mouse |
|
|
regulation of apoptotic dna fragmentation
|
GO:1902510 |
3 |
0.391
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.389
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.386
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.382
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.379
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.379
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.378
|
Human |
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.378
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.377
|
Human |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.373
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.370
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.366
|
|
|
|
secondary metabolic process
|
GO:0019748 |
17 |
0.358
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.356
|
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.356
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.354
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.340
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.336
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.334
|
|
|
|
head development
|
GO:0060322 |
108 |
0.333
|
Human |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.332
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.331
|
Human |
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.320
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.318
|
Rat |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.311
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.305
|
Human |
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.300
|
Human |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.298
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.297
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.292
|
Human |
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
37 |
0.291
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.289
|
Mouse |
|
|
response to nicotine
|
GO:0035094 |
12 |
0.285
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.278
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.276
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.275
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.274
|
Human |
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.274
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.268
|
Human |
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.260
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.250
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.249
|
Human |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.249
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
7 |
0.249
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.246
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.245
|
Human |
|
|
positive regulation of protein linear polyubiquitination
|
GO:1902530 |
2 |
0.243
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.242
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.240
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.239
|
Human Mouse |
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
8 |
0.233
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.231
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.230
|
Mouse |
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.229
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.226
|
Rat |
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.224
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.223
|
Rat |
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.219
|
|
|
|
macrophage differentiation
|
GO:0030225 |
11 |
0.217
|
Human |
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.217
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.214
|
Human |
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.211
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.211
|
Human |
|
|
b cell homeostasis
|
GO:0001782 |
1 |
0.210
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.209
|
Rat |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.207
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.205
|
Rat |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.201
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.200
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.199
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.198
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.198
|
Human |
|
|
regulation of glial cell apoptotic process
|
GO:0034350 |
6 |
0.198
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.195
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.195
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.192
|
Human |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.189
|
Human |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.183
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.183
|
Human |
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.182
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.181
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.180
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.177
|
Human |
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.177
|
Human |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.172
|
Human |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.172
|
Human |
|
|
response to estradiol
|
GO:0032355 |
23 |
0.172
|
Rat |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.171
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.171
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.170
|
Human |
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.170
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.169
|
Human |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.167
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.166
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.165
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.164
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.162
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.162
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.161
|
Human |
|
|
response to glucocorticoid
|
GO:0051384 |
13 |
0.160
|
Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.159
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.156
|
Mouse |
|
|
regulation of dna catabolic process
|
GO:1903624 |
7 |
0.152
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.151
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.144
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.143
|
|
|
|
negative regulation of mononuclear cell proliferation
|
GO:0032945 |
15 |
0.143
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.143
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.142
|
Mouse |
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.141
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.141
|
Human |
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.138
|
Human |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.137
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.136
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.136
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.135
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.132
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
12 |
0.132
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.131
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.128
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.128
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.126
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.126
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.126
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.124
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.122
|
Human |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.122
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.121
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.121
|
Human |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.119
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.116
|
|
|
|
system process
|
GO:0003008 |
349 |
0.115
|
Zebrafish |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.114
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.113
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.113
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.113
|
|
|
|
organic acid catabolic process
|
GO:0016054 |
71 |
0.113
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.113
|
Rat |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.112
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.111
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.110
|
Mouse Rat |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.109
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.106
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.106
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.106
|
|
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.105
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.105
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.104
|
Human |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.104
|
|
|
|
positive regulation of protein polyubiquitination
|
GO:1902916 |
3 |
0.104
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.103
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.103
|
Human |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.103
|
Human |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.102
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.101
|
Human |
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.099
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.098
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.096
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.096
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.096
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.095
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.095
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.094
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.093
|
Human Zebrafish Mouse Rat |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.092
|
|
|
|
pigment metabolic process
|
GO:0042440 |
16 |
0.091
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.090
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.090
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.088
|
Human |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.088
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
11 |
0.087
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.086
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.086
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.086
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.086
|
|
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.085
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.085
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.084
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.084
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.081
|
Human |
|
|
regulation of protein linear polyubiquitination
|
GO:1902528 |
2 |
0.080
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.080
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.080
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.080
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.079
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.077
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003256 |
3 |
0.077
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.076
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.073
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.073
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.072
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.072
|
Mouse |
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.071
|
Mouse |
|
|
positive regulation of mhc class i biosynthetic process
|
GO:0045345 |
4 |
0.071
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.071
|
Human |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.069
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.068
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.067
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.067
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.067
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.066
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.066
|
Human |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.066
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.065
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.064
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.063
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.062
|
Mouse |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.062
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.060
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.059
|
Human |
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.059
|
Human |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.058
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.057
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.057
|
|
|
|
neuron cellular homeostasis
|
GO:0070050 |
3 |
0.056
|
|
|
|
response to glucose
|
GO:0009749 |
19 |
0.056
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.056
|
Human |
|
|
negative regulation of b cell activation
|
GO:0050869 |
6 |
0.056
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.054
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.054
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.053
|
|
|
|
cardiac ventricle formation
|
GO:0003211 |
2 |
0.053
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.053
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.052
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.051
|
|
|
|
regulation of protein k63 linked ubiquitination
|
GO:1900044 |
6 |
0.051
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.050
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.049
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.049
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.049
|
Mouse |
|
|
necroptotic process
|
GO:0070266 |
16 |
0.049
|
|
|
|
natural killer cell apoptotic process
|
GO:0070246 |
1 |
0.047
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.047
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.047
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.047
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.047
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.047
|
Mouse Rat |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.046
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.046
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.045
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.045
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.045
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.045
|
Mouse Rat |
|
|
cellular response to retinoic acid
|
GO:0071300 |
19 |
0.044
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.044
|
Rat |
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.044
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.043
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.041
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.041
|
Human |
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.041
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.041
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
5 |
0.040
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
1 |
0.040
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.040
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.040
|
Human |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.039
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
24 |
0.039
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.039
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.038
|
Human |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.038
|
|
|
|
regulation of protein monoubiquitination
|
GO:1902525 |
1 |
0.038
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.038
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.037
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.037
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.036
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.036
|
|
|
|
regulation of anion transport
|
GO:0044070 |
25 |
0.036
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.035
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.035
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.035
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.035
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.035
|
Mouse Rat |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.035
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.034
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.034
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.033
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.032
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.032
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.032
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.032
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.032
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.031
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.030
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.030
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.030
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.030
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.030
|
|
|
|
cardiac chamber formation
|
GO:0003207 |
2 |
0.029
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.029
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.029
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.028
|
|
|
|
growth
|
GO:0040007 |
202 |
0.028
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.027
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.027
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.027
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.026
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.026
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.026
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.026
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.025
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.025
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.025
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.025
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.025
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c
|
GO:0008635 |
2 |
0.025
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.024
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.024
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.024
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.024
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.024
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.024
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.023
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.023
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.023
|
Human |
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.023
|
|
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.023
|
|
|
|
positive regulation of protein k48 linked ubiquitination
|
GO:1902524 |
1 |
0.023
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.023
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.023
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.023
|
|
|
|
dendritic cell antigen processing and presentation
|
GO:0002468 |
1 |
0.022
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.022
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.022
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.022
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.022
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.022
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.022
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.022
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.021
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.021
|
|
|
|
aging
|
GO:0007568 |
66 |
0.021
|
Rat |
|
|
sensory perception
|
GO:0007600 |
103 |
0.021
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.021
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.021
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.021
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.021
|
Human |
|
|
regulation of natural killer cell apoptotic process
|
GO:0070247 |
1 |
0.021
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
4 |
0.021
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.021
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.021
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.021
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.021
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.021
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.021
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.020
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.020
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.020
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.020
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.020
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.020
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.020
|
|
|
|
regulation of mesonephros development
|
GO:0061217 |
3 |
0.020
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.020
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.020
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.020
|
|
|
|
memory
|
GO:0007613 |
3 |
0.020
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.020
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.020
|
Human |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.020
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.019
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.019
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.019
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.019
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.019
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.019
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.019
|
Rat |
|
|
organ formation
|
GO:0048645 |
3 |
0.019
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
7 |
0.019
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.019
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.019
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.019
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.019
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.019
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.019
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
4 |
0.019
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.019
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.019
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.019
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.019
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.018
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.018
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.018
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.018
|
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
65 |
0.018
|
|
|
|
regulation of protein polyubiquitination
|
GO:1902914 |
8 |
0.018
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.018
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.018
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.018
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.018
|
Human |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.018
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.018
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.018
|
Human |
|
|
coronary vasculature development
|
GO:0060976 |
2 |
0.018
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.018
|
Human |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.017
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.017
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.017
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.017
|
|
