|
|
positive regulation of vasoconstriction
|
GO:0045907 |
3 |
0.963
|
|
|
|
parturition
|
GO:0007567 |
1 |
0.931
|
Worm |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.891
|
|
|
|
caveola assembly
|
GO:0070836 |
4 |
0.886
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.870
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.867
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.861
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
2 |
0.859
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
2 |
0.829
|
|
|
|
regulation of the force of heart contraction
|
GO:0002026 |
6 |
0.821
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.821
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.810
|
|
|
|
positive regulation of g protein coupled receptor protein signaling pathway
|
GO:0045745 |
9 |
0.800
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.799
|
|
|
|
plasma membrane raft organization
|
GO:0044857 |
4 |
0.799
|
|
|
|
inactivation of mapk activity
|
GO:0000188 |
5 |
0.780
|
|
|
|
dopamine receptor signaling pathway
|
GO:0007212 |
10 |
0.773
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
2 |
0.748
|
|
|
|
cellular response to hyperoxia
|
GO:0071455 |
4 |
0.745
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.725
|
Mouse |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.712
|
|
|
|
receptor internalization involved in canonical wnt signaling pathway
|
GO:2000286 |
3 |
0.697
|
Human |
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
4 |
0.696
|
Human |
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
1 |
0.687
|
|
|
|
regulation of dopamine receptor signaling pathway
|
GO:0060159 |
3 |
0.685
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.662
|
Human Mouse |
|
|
negative regulation of nitric oxide biosynthetic process
|
GO:0045019 |
5 |
0.660
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.657
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.651
|
|
|
|
regulation of pinocytosis
|
GO:0048548 |
6 |
0.644
|
Human |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.636
|
Human |
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.616
|
|
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.603
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.580
|
|
|
|
positive regulation of neutrophil apoptotic process
|
GO:0033031 |
1 |
0.572
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.501
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.494
|
Worm |
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.490
|
|
|
|
intestinal cholesterol absorption
|
GO:0030299 |
4 |
0.486
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.478
|
Human |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.473
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.473
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.469
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.464
|
Human |
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.458
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.451
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.444
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.442
|
Human |
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.439
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.438
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.438
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.438
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.433
|
Human |
|
|
vein smooth muscle contraction
|
GO:0014826 |
4 |
0.432
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.422
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.421
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.420
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.418
|
Human |
|
|
membrane organization
|
GO:0061024 |
292 |
0.414
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.400
|
|
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.385
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.367
|
Worm |
|
|
response to wounding
|
GO:0009611 |
168 |
0.360
|
Human |
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.360
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.356
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.355
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.352
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.349
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.348
|
Human |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.343
|
Human Mouse |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.343
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.340
|
Human |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.337
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.335
|
|
|
|
regulation of the force of heart contraction by chemical signal
|
GO:0003057 |
1 |
0.333
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.331
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.325
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.323
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.322
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.319
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.316
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.314
|
|
|
|
regulation of eosinophil activation
|
GO:1902566 |
2 |
0.313
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.310
|
Human Mouse |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.309
|
Human |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.307
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.293
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.293
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.291
|
|
|
|
lipid digestion
|
GO:0044241 |
6 |
0.286
|
|
|
|
negative regulation of nitric oxide synthase activity
|
GO:0051001 |
3 |
0.285
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.279
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.278
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.274
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.271
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.271
|
|
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.270
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.269
|
Human |
|
|
negative regulation of pinocytosis
|
GO:0048550 |
4 |
0.257
|
Human |
|
|
chemokine c c motif ligand 2 secretion
|
GO:0035926 |
1 |
0.256
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.254
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.252
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.249
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.247
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.243
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.239
|
Human |
|
|
muscle system process
|
GO:0003012 |
81 |
0.239
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.237
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.236
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.236
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.235
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.234
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.231
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.229
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.227
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.224
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.223
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.222
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.222
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.220
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.217
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.216
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.216
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.214
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.213
|
|
|
|
regulation of metalloenzyme activity
|
GO:0048552 |
3 |
0.213
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
5 |
0.211
|
|
|
|
vasoconstriction
|
GO:0042310 |
11 |
0.210
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.210
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.209
|
|
|
|
endocrine process
|
GO:0050886 |
25 |
0.208
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.207
|
Human |
|
|
positive regulation of eosinophil degranulation
|
GO:0043311 |
1 |
0.206
|
|
|
|
neutrophil mediated killing of gram negative bacterium
|
GO:0070945 |
1 |
0.205
|
|
|
|
tonic smooth muscle contraction
|
GO:0014820 |
3 |
0.205
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
12 |
0.203
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.202
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.200
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
14 |
0.200
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.199
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
2 |
0.199
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.199
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.198
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.190
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.187
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.187
|
|
|
|
negative regulation of chemokine secretion
|
GO:0090198 |
1 |
0.187
|
|
|
|
system process
|
GO:0003008 |
349 |
0.186
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.185
|
Worm |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.184
|
Worm |
|
|
behavior
|
GO:0007610 |
112 |
0.183
|
Worm |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.182
|
Mouse |
|
|
intestinal absorption
|
GO:0050892 |
4 |
0.179
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.178
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.177
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.175
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.173
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.173
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.173
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.171
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.171
|
Mouse |
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.166
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.164
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.164
|
Human |
|
|
regulation of neutrophil mediated killing of bacterium
|
GO:0070950 |
1 |
0.162
|
|
|
|
eosinophil activation
|
GO:0043307 |
3 |
0.162
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.161
|
Human |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.160
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.159
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.159
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.158
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.158
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.158
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.157
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.157
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.157
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.156
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.154
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.154
|
Human Mouse |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.152
|
Human |
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.151
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.150
|
|
|
|
positive regulation of toll like receptor 3 signaling pathway
|
GO:0034141 |
1 |
0.149
|
|
|
|
regulation of tube size
|
GO:0035150 |
18 |
0.149
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.149
|
Human |
|
|
transcription initiation from rna polymerase i promoter
|
GO:0006361 |
2 |
0.148
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.148
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.147
|
Mouse |
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.147
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.145
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.145
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.143
|
|
|
|
positive regulation of calcium ion transport into cytosol
|
GO:0010524 |
20 |
0.141
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.141
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.140
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.140
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.139
|
Human |
|
|
membrane biogenesis
|
GO:0044091 |
13 |
0.138
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.137
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.137
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.136
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.134
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.134
|
Human |
|
|
lipid localization
|
GO:0010876 |
106 |
0.134
|
Worm |
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.133
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.133
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.132
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.130
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.130
|
Human |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.129
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.128
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.127
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.127
|
Human |
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.127
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.126
|
Human |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.125
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.125
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.124
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.123
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.123
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.123
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.122
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.122
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
6 |
0.122
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.122
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.121
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.121
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.120
|
|
|
|
regulation of neurotrophin trk receptor signaling pathway
|
GO:0051386 |
2 |
0.120
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.120
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.120
|
|
|
|
positive regulation of toll like receptor 2 signaling pathway
|
GO:0034137 |
2 |
0.119
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.119
|
Human |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.118
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.117
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.116
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.116
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.116
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.115
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.115
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.114
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.113
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
28 |
0.113
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.112
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.112
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.112
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.109
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.109
|
|
|
|
vesicle fusion
|
GO:0006906 |
17 |
0.107
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.107
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.107
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.106
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.106
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.106
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.106
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.105
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.105
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.105
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.105
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.104
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
14 |
0.104
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.102
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.102
|
Human |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.101
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.101
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.101
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.101
|
|
|
|
vesicle docking
|
GO:0048278 |
5 |
0.101
|
|
|
|
regulation of neutrophil mediated killing of gram negative bacterium
|
GO:0070951 |
1 |
0.100
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.100
|
Mouse |
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.100
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.100
|
|
|
|
growth
|
GO:0040007 |
202 |
0.099
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.099
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.099
|
|
|
|
termination of rna polymerase i transcription
|
GO:0006363 |
1 |
0.097
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.097
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.097
|
Human |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.096
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.095
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
2 |
0.095
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.095
|
|
|
|
mating
|
GO:0007618 |
1 |
0.094
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.093
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.092
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.091
|
Human |
|
|
neutrophil mediated immunity
|
GO:0002446 |
4 |
0.091
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.091
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.090
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.090
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.089
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.089
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.089
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.088
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.088
|
Mouse |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.088
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.088
|
|
|
|
regulation of sensory perception
|
GO:0051931 |
3 |
0.088
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.086
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.086
|
Human |
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.085
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.085
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.085
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.085
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.085
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.084
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.084
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.084
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.084
|
|
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.083
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.083
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.083
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.083
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.082
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.082
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.082
|
|
|
|
dna templated transcription termination
|
GO:0006353 |
3 |
0.082
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.082
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.081
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.081
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.081
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.081
|
Human |
|
|
interleukin 1 secretion
|
GO:0050701 |
18 |
0.080
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.080
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.079
|
Mouse |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.079
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.079
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.079
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.079
|
Human |
|
|
sterol homeostasis
|
GO:0055092 |
28 |
0.078
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.078
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.078
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.077
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.076
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.076
|
|
|
|
positive regulation of neutrophil mediated cytotoxicity
|
GO:0070960 |
1 |
0.075
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.075
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.075
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.075
|
|
|
|
midgut development
|
GO:0007494 |
1 |
0.075
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.074
|
|
|
|
cellular hormone metabolic process
|
GO:0034754 |
41 |
0.073
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.073
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.073
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.073
|
|
|
|
renal system process involved in regulation of blood volume
|
GO:0001977 |
4 |
0.073
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.073
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.072
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.072
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
3 |
0.072
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.072
|
Human |
|
|
triglyceride metabolic process
|
GO:0006641 |
23 |
0.072
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.072
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.072
|
Mouse |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.072
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.071
|
|
|
|
regulation of systemic arterial blood pressure by hormone
|
GO:0001990 |
12 |
0.071
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.070
|
|
|
|
spinal cord dorsal ventral patterning
|
GO:0021513 |
2 |
0.070
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.070
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.070
|
|
|
|
membrane raft organization
|
GO:0031579 |
10 |
0.069
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.069
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.068
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.068
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.067
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.067
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.067
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.066
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.066
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.066
|
|
|
|
artery smooth muscle contraction
|
GO:0014824 |
3 |
0.065
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.065
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.065
|
Human |
|
|
regulation of sensory perception of pain
|
GO:0051930 |
3 |
0.064
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.064
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.064
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.063
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.062
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.062
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.062
|
Human |
|
|
pinocytosis
|
GO:0006907 |
8 |
0.061
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.061
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.061
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.060
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.060
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.060
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.060
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.060
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.059
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.059
|
|
|
|
regulation of neutrophil apoptotic process
|
GO:0033029 |
1 |
0.059
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.059
|
Mouse |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.059
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.059
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.059
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.059
|
Worm |
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.058
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.058
|
|
|
|
positive regulation of neutrophil mediated killing of bacterium
|
GO:0070962 |
1 |
0.057
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.056
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
7 |
0.056
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.056
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.056
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.055
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.055
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.055
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.055
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.055
|
|
|
|
positive regulation of metalloenzyme activity
|
GO:0048554 |
2 |
0.054
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.054
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.054
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.054
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.054
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.054
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.054
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.054
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.053
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.053
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.053
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.053
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.053
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.053
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.053
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.052
|
Human |
|
|
digestive system process
|
GO:0022600 |
17 |
0.052
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.052
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.051
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.051
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.051
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.051
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.051
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.051
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.050
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.050
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.050
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.050
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.050
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.049
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.049
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.049
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.048
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.048
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.048
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.048
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.048
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.047
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.047
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.047
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.047
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.047
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.047
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.047
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.047
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.047
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.047
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.047
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.046
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.046
|
Mouse |
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.046
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.046
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.046
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.046
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.046
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.046
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.046
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.046
|
|
|
|
membrane raft assembly
|
GO:0001765 |
7 |
0.045
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.045
|
|
|
|
regulation of keratinocyte proliferation
|
GO:0010837 |
11 |
0.045
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.045
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.045
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.045
|
Human |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.045
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.045
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.044
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.044
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.044
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.044
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.044
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.044
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.043
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.043
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.043
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.043
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.043
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.043
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.043
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.043
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.043
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.042
|
|
|
|
positive regulation of cytokine secretion involved in immune response
|
GO:0002741 |
2 |
0.042
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.042
|
|