|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
1.000
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
1.000
|
Human Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
1.000
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
Human Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
1.000
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
1.000
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
1.000
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
1.000
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
1.000
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
1.000
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
1.000
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
1.000
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
1.000
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
1.000
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
1.000
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
1.000
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
1.000
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
1.000
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
1.000
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
1.000
|
Human Fly |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
1.000
|
Human Fly |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
1.000
|
Human Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
1.000
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
1.000
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
1.000
|
Human Fly |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
1.000
|
Human Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
1.000
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
1.000
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
1.000
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
1.000
|
Human Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
1.000
|
Human Fly |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
1.000
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
1.000
|
|
|
|
cell development
|
GO:0048468 |
328 |
1.000
|
Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
1.000
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
1.000
|
Human Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
1.000
|
Human Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
1.000
|
|
|
|
nerve growth factor signaling pathway
|
GO:0038180 |
4 |
1.000
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
1.000
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
1.000
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
1.000
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
1.000
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
1.000
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
1.000
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
1.000
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
1.000
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
1.000
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
1.000
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
1.000
|
Human Fly |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
1.000
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
1.000
|
|
|
|
nerve development
|
GO:0021675 |
4 |
1.000
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
1.000
|
Fly |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
1.000
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.999
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.999
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.999
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.999
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.999
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.999
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.999
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.999
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.999
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.999
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.999
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.999
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.999
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.999
|
Fly |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.999
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.999
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.998
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.998
|
Human Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.998
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.998
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.998
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.998
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.998
|
Fly |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.998
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.997
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.997
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.997
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.997
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.997
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.996
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.996
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.996
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.996
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.996
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.996
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.996
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.996
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.995
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.995
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.995
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.995
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.995
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.995
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.994
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.994
|
Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.994
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.993
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.992
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.992
|
Human Fly |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.992
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.991
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.991
|
Human Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.991
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.991
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.991
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.991
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.991
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.991
|
Human Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.990
|
Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.990
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.990
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.990
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.989
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.989
|
Human Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.989
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.989
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.989
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.988
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.988
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.987
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.987
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.987
|
Human Fly |
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.985
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.985
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.985
|
|
|
|
glial cell development
|
GO:0021782 |
7 |
0.985
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.984
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.984
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.984
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.983
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.983
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.982
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.982
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.982
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.982
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.981
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.980
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.979
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.979
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.976
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.976
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.976
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.975
|
|
|
|
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038091 |
3 |
0.975
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.974
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.974
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.974
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.974
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.973
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.972
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.972
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.971
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.970
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.969
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.969
|
Fly |
|
|
negative regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040037 |
2 |
0.968
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.967
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.967
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.967
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.967
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.966
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.965
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.963
|
Fly |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.963
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.963
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.962
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.962
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.961
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.961
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.959
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.958
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.957
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.956
|
Human Fly |
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.956
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.955
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.955
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.954
|
|
|
|
vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038086 |
3 |
0.954
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.953
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.953
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.950
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.950
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.950
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.949
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.947
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.947
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.943
|
|
|
|
fc receptor signaling pathway
|
GO:0038093 |
2 |
0.940
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.939
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.937
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.936
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.934
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.931
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.927
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.926
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.926
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.925
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.924
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.922
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.922
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.921
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.920
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.920
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.918
|
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.917
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.917
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.916
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
5 |
0.916
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.915
|
|
|
|
macrophage activation involved in immune response
|
GO:0002281 |
1 |
0.914
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.912
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.911
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.908
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.905
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.904
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.904
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.900
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.899
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.897
|
|
|
|
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling
|
GO:0060665 |
1 |
0.897
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.895
|
|
|
|
growth
|
GO:0040007 |
202 |
0.894
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.893
|
Fly |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.891
|
Fly |
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.888
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.887
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.887
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.887
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.886
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.885
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.884
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.884
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.879
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.875
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.872
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.871
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.870
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.870
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.868
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.865
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.864
|
|
|
|
negative regulation of blood coagulation
|
GO:0030195 |
22 |
0.862
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.862
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.861
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.860
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.856
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.855
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.855
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.854
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.853
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.851
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.846
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.839
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.834
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.833
|
Fly |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.833
|
Human Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.827
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.826
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.821
|
|
|
|
negative regulation of neurotrophin trk receptor signaling pathway
|
GO:0051387 |
2 |
0.819
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.819
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.818
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.818
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.817
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.813
|
Human Fly |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.811
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.810
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.810
|
|
|
|
cell death in response to hydrogen peroxide
|
GO:0036474 |
10 |
0.809
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.807
|
Fly |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.806
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.803
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.803
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.798
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.795
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.794
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.793
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
7 |
0.791
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
7 |
0.783
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.781
|
Fly |
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.775
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.770
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.770
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.766
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.766
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.759
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.759
|
|
|
|
negative regulation of coagulation
|
GO:0050819 |
24 |
0.756
|
|
|
|
regulation of neurotrophin trk receptor signaling pathway
|
GO:0051386 |
2 |
0.755
|
|
|
|
regulation of arf protein signal transduction
|
GO:0032012 |
1 |
0.755
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.754
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.753
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.752
|
Fly |
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.750
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.746
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.744
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.741
|
|
|
|
negative regulation of hydrogen peroxide mediated programmed cell death
|
GO:1901299 |
3 |
0.737
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.737
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.730
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.727
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.727
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.726
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.726
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.725
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.724
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.724
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.724
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
12 |
0.723
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.722
|
|
|
|
programmed cell death in response to reactive oxygen species
|
GO:0097468 |
4 |
0.720
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.720
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.720
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.717
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.716
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.710
|
|
|
|
glial cell differentiation
|
GO:0010001 |
11 |
0.707
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.705
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.704
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.704
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.700
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.697
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.690
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.683
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.682
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.678
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.676
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.669
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.668
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.666
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.666
|
|
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.665
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.665
|
Fly |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.661
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.659
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.658
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.653
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.650
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.642
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.641
|
|
|
|
negative regulation of platelet activation
|
GO:0010544 |
7 |
0.637
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.637
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.634
|
Human |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.630
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.629
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.627
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.625
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.625
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.624
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.623
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.623
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.620
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
25 |
0.619
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.619
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.617
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.616
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.612
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.612
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.609
|
|
|
|
regulation of hormone biosynthetic process
|
GO:0046885 |
10 |
0.606
|
Fly |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.606
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.606
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.601
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.600
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.600
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.598
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.598
|
|
|
|
negative regulation of antigen receptor mediated signaling pathway
|
GO:0050858 |
6 |
0.596
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
7 |
0.593
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.590
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.589
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.586
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
15 |
0.586
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
2 |
0.583
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.583
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.583
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.582
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.581
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.581
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.579
|
Fly |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.578
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.568
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.568
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.568
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.565
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.564
|
|
|
|
hydrogen peroxide mediated programmed cell death
|
GO:0010421 |
4 |
0.562
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.560
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
7 |
0.560
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
1 |
0.558
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.555
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.554
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.549
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.545
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.544
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.544
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.541
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.538
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.538
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.534
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.533
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.532
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.532
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.531
|
|
|
|
arf protein signal transduction
|
GO:0032011 |
0 |
0.531
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.527
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.526
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.525
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.521
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.520
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.517
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.508
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.508
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.507
|
|
|
|
regulation of non canonical wnt signaling pathway
|
GO:2000050 |
4 |
0.507
|
|
|
|
muscle fiber development
|
GO:0048747 |
16 |
0.505
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.499
|
Fly |
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.498
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.497
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.496
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.494
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.491
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.490
|
|
|
|
negative regulation of hemostasis
|
GO:1900047 |
22 |
0.483
|
|
|
|
positive regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000096 |
2 |
0.481
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.480
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.479
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.475
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.475
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.474
|
|
|
|
positive regulation of metanephros development
|
GO:0072216 |
3 |
0.474
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.474
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.474
|
Human Fly |
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.473
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.472
|
Fly |
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.467
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.464
|
Fly |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.463
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.457
|
|
|
|
lung growth
|
GO:0060437 |
2 |
0.457
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.456
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.456
|
|
|
|
system process
|
GO:0003008 |
349 |
0.452
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.445
|
|
|
|
regulation of peptidyl threonine phosphorylation
|
GO:0010799 |
15 |
0.441
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.440
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.439
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.437
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.437
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.436
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.434
|
|
|
|
neuron migration
|
GO:0001764 |
11 |
0.432
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.431
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.426
|
|
|
|
lymphangiogenesis
|
GO:0001946 |
7 |
0.425
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.424
|
Human |
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.423
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.421
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.419
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.417
|
|
|
|
regulation of hydrogen peroxide induced cell death
|
GO:1903205 |
10 |
0.411
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.410
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.408
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.405
|
|
|
|
negative regulation of homotypic cell cell adhesion
|
GO:0034111 |
3 |
0.405
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.398
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.397
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.395
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.393
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.387
|
|
|
|
neuron cell cell adhesion
|
GO:0007158 |
1 |
0.383
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.380
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.378
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.377
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.376
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.376
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.371
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.367
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.367
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.364
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.361
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.358
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.357
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.356
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.355
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.355
|
|
