Homo sapiens

64 known processes

CBX3

chromobox homolog 3

(Aliases: HECH,HP1-GAMMA,HP1Hs-gamma)

CBX3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
dna hypermethylation GO:0044026 1 1.000
Fly
chromatin assembly or disassembly GO:0006333 78 0.995
Fly
peptidyl lysine dimethylation GO:0018027 3 0.992
Fly
protein dna complex assembly GO:0065004 64 0.989
nucleosome assembly GO:0006334 50 0.956
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.948
Fly
chromatin organization GO:0006325 351 0.926
Fly
chromatin modification GO:0016568 298 0.893
Fly
mitotic sister chromatid segregation GO:0000070 53 0.870
mitotic cell cycle GO:0000278 326 0.811
regulation of cell differentiation GO:0045595 393 0.782
Worm
cellular macromolecular complex assembly GO:0034622 324 0.755
protein methylation GO:0006479 74 0.680
Fly
histone lysine methylation GO:0034968 50 0.673
Fly
dna packaging GO:0006323 77 0.650
Fly
regulation of heterochromatin assembly GO:0031445 1 0.583
Fly
regulation of growth rate GO:0040009 1 0.562
Worm
cellular amino acid metabolic process GO:0006520 116 0.559
chromatin remodeling GO:0006338 55 0.545
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.532
negative regulation of chromosome organization GO:2001251 48 0.524
Fly
mitotic cell cycle process GO:1903047 286 0.523
heterochromatin organization GO:0070828 6 0.520
Fly
oogenesis GO:0048477 2 0.520
Worm
peptidyl lysine methylation GO:0018022 37 0.489
Fly
histone modification GO:0016570 251 0.453
Fly
positive regulation of chromatin modification GO:1903310 30 0.444
Fly
covalent chromatin modification GO:0016569 254 0.440
Fly
positive regulation of dna metabolic process GO:0051054 73 0.440
Fly
positive regulation of cell differentiation GO:0045597 211 0.430
regulation of cellular amine metabolic process GO:0033238 11 0.379
regulation of gene silencing GO:0060968 24 0.367
Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.339
cellular amine metabolic process GO:0044106 41 0.333
associative learning GO:0008306 1 0.324
Worm
organophosphate biosynthetic process GO:0090407 163 0.317
amine metabolic process GO:0009308 44 0.304
positive regulation of developmental process GO:0051094 314 0.302
Worm
mitotic nuclear division GO:0007067 119 0.294
macromolecule methylation GO:0043414 97 0.292
Fly
regulation of dna methylation GO:0044030 2 0.286
Fly
chromosome segregation GO:0007059 114 0.284
meiotic chromosome segregation GO:0045132 4 0.283
organelle fission GO:0048285 149 0.280
histone methylation GO:0016571 60 0.271
Fly
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.263
protein maturation GO:0051604 233 0.251
dna replication dependent nucleosome organization GO:0034723 32 0.237
nucleosome organization GO:0034728 66 0.221
regulation of meiotic cell cycle GO:0051445 4 0.205
nuclear division GO:0000280 128 0.201
histone h3 k9 modification GO:0061647 11 0.192
Fly
regulation of cell growth GO:0001558 135 0.177
protein alkylation GO:0008213 74 0.173
Fly
positive regulation of multicellular organism growth GO:0040018 6 0.172
Worm
protein glycosylation GO:0006486 62 0.168
peptidyl lysine modification GO:0018205 144 0.167
Fly
developmental process involved in reproduction GO:0003006 66 0.166
Worm
cell development GO:0048468 328 0.166
Worm
regulation of cellular amino acid metabolic process GO:0006521 6 0.166
tube development GO:0035295 125 0.156
purine nucleotide biosynthetic process GO:0006164 84 0.150
cellular protein complex assembly GO:0043623 188 0.147
regulation of cellular component biogenesis GO:0044087 281 0.139
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.130
heterochromatin assembly GO:0031507 6 0.127
Fly
meiotic nuclear division GO:0007126 10 0.121
nucleoside phosphate biosynthetic process GO:1901293 109 0.119
negative regulation of cellular component organization GO:0051129 235 0.117
Fly
nucleotide biosynthetic process GO:0009165 109 0.113
response to steroid hormone GO:0048545 80 0.110
single organism reproductive process GO:0044702 98 0.109
Worm
positive regulation of chromosome organization GO:2001252 41 0.108
Fly
female gamete generation GO:0007292 2 0.107
Worm
peptidyl lysine trimethylation GO:0018023 10 0.107
Fly
histone h3 k9 methylation GO:0051567 10 0.105
Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.105
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.104
Fly
carbohydrate metabolic process GO:0005975 207 0.103
cellular response to hormone stimulus GO:0032870 125 0.102
post embryonic development GO:0009791 2 0.094
Worm
gene silencing GO:0016458 49 0.093
Fly
regulation of chromatin silencing GO:0031935 8 0.089
Fly
regulation of proteasomal protein catabolic process GO:0061136 87 0.088
regulation of proteolysis GO:0030162 293 0.088
positive regulation of apoptotic process GO:0043065 246 0.086
response to lipid GO:0033993 206 0.084
reproductive process GO:0022414 106 0.082
Worm
positive regulation of hydrolase activity GO:0051345 331 0.082
regulation of meiosis GO:0040020 3 0.080
viral process GO:0016032 146 0.078
cell projection organization GO:0030030 252 0.078
dna conformation change GO:0071103 113 0.073
Fly
negative regulation of neuron apoptotic process GO:0043524 23 0.072
positive regulation of growth GO:0045927 58 0.070
Worm
purine ribonucleotide biosynthetic process GO:0009152 79 0.070
small gtpase mediated signal transduction GO:0007264 78 0.068
Worm
posttranscriptional gene silencing GO:0016441 25 0.067
positive regulation of cgmp biosynthetic process GO:0030828 3 0.067
negative regulation of gene expression epigenetic GO:0045814 19 0.065
Fly
regulation of cysteine type endopeptidase activity GO:2000116 127 0.064
regulation of mitotic cell cycle GO:0007346 189 0.063
regulation of histone methylation GO:0031060 16 0.063
Fly
ameboidal type cell migration GO:0001667 135 0.062
regulation of gene expression epigenetic GO:0040029 73 0.062
Fly
regulation of chromatin assembly GO:0010847 2 0.062
Fly
neuron differentiation GO:0030182 138 0.061
embryo development GO:0009790 123 0.061
generation of neurons GO:0048699 152 0.061
neuron development GO:0048666 113 0.060
reproductive system development GO:0061458 56 0.060
Worm
mature ribosome assembly GO:0042256 5 0.059
negative regulation of dna metabolic process GO:0051053 57 0.059
Fly
negative regulation of protein metabolic process GO:0051248 391 0.058
cell type specific apoptotic process GO:0097285 125 0.057
rna interference GO:0016246 4 0.057
regulation of viral process GO:0050792 103 0.057
positive regulation of transferase activity GO:0051347 227 0.056
single organism carbohydrate metabolic process GO:0044723 193 0.055
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.055
purine containing compound biosynthetic process GO:0072522 88 0.055
response to hormone GO:0009725 175 0.054
positive regulation of cellular component biogenesis GO:0044089 158 0.054
Fly
multicellular organismal reproductive process GO:0048609 40 0.051
Worm
rna splicing GO:0008380 131 0.051
neurogenesis GO:0022008 169 0.049
Fly
spermatid development GO:0007286 4 0.048
activation of cysteine type endopeptidase activity GO:0097202 57 0.047
positive regulation of histone h3 k9 methylation GO:0051574 3 0.047
Fly
regulation of binding GO:0051098 111 0.046
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.045
cell morphogenesis GO:0000902 296 0.045
methylation GO:0032259 106 0.044
Fly
negative regulation of proteolysis GO:0045861 132 0.044
digestive tract morphogenesis GO:0048546 56 0.044
determination of adult lifespan GO:0008340 2 0.043
positive regulation of neurogenesis GO:0050769 49 0.043
positive regulation of histone methylation GO:0031062 12 0.042
Fly
regulation of endopeptidase activity GO:0052548 170 0.042
regulation of cell cycle GO:0051726 393 0.041
positive regulation of cell development GO:0010720 92 0.041
nucleocytoplasmic transport GO:0006913 176 0.040
regulation of dna metabolic process GO:0051052 153 0.040
Fly
positive regulation of endopeptidase activity GO:0010950 84 0.040
dna replication dependent nucleosome assembly GO:0006335 32 0.040
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.038
interspecies interaction between organisms GO:0044419 156 0.038
positive regulation of cytoplasmic transport GO:1903651 82 0.038
negative regulation of catalytic activity GO:0043086 335 0.037
system process GO:0003008 349 0.037
Worm
regulation of locomotion GO:0040012 329 0.037
cognition GO:0050890 43 0.036
Worm
hemopoiesis GO:0030097 180 0.036
sister chromatid segregation GO:0000819 54 0.035
negative regulation of cell cycle GO:0045786 193 0.035
positive regulation of cell projection organization GO:0031346 64 0.034
cell projection morphogenesis GO:0048858 129 0.034
positive regulation of cell death GO:0010942 263 0.034
regulation of ras protein signal transduction GO:0046578 155 0.034
Worm
regulation of cell migration GO:0030334 289 0.034
behavior GO:0007610 112 0.034
Worm
multicellular organism reproduction GO:0032504 42 0.033
Worm
regulation of small gtpase mediated signal transduction GO:0051056 156 0.033
Worm
cellular response to organic cyclic compound GO:0071407 127 0.033
chromatin silencing GO:0006342 12 0.033
Fly
mrna processing GO:0006397 133 0.033
positive regulation of programmed cell death GO:0043068 249 0.032
reproductive structure development GO:0048608 55 0.032
Worm
negative regulation of mitotic cell cycle GO:0045930 102 0.031
dna replication independent nucleosome assembly GO:0006336 27 0.031
neuron projection development GO:0031175 106 0.031
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.031
regulation of chromosome organization GO:0033044 103 0.030
Fly
dna modification GO:0006304 27 0.029
Fly
regulation of peptidase activity GO:0052547 180 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.029
response to organic cyclic compound GO:0014070 204 0.029
cellular protein catabolic process GO:0044257 261 0.027
meiotic cell cycle GO:0051321 13 0.027
regulation of histone modification GO:0031056 47 0.027
Fly
macromolecule glycosylation GO:0043413 63 0.026
oocyte development GO:0048599 1 0.026
nuclear export GO:0051168 69 0.026
oocyte differentiation GO:0009994 2 0.025
ras protein signal transduction GO:0007265 73 0.025
Worm
protein acetylation GO:0006473 116 0.025
sex differentiation GO:0007548 45 0.025
Worm
positive regulation of peptidase activity GO:0010952 88 0.025
carbohydrate derivative biosynthetic process GO:1901137 207 0.025
zymogen activation GO:0031638 70 0.025
growth GO:0040007 202 0.025
Worm
regulation of growth GO:0040008 165 0.024
Worm
regulation of cell development GO:0060284 161 0.024
protein acylation GO:0043543 138 0.024
regulation of nuclear division GO:0051783 65 0.024
nucleoside monophosphate metabolic process GO:0009123 191 0.023
myeloid cell differentiation GO:0030099 117 0.023
negative regulation of protein maturation GO:1903318 142 0.023
digestive tract development GO:0048565 75 0.023
regulation of cellular response to stress GO:0080135 244 0.023
neuron projection morphogenesis GO:0048812 50 0.023
gene silencing by rna GO:0031047 26 0.023
cell growth GO:0016049 160 0.022
spermatid differentiation GO:0048515 4 0.022
cellular ketone metabolic process GO:0042180 80 0.022
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.021
protein o linked glycosylation GO:0006493 21 0.021
dendrite development GO:0016358 24 0.021
positive regulation of organelle organization GO:0010638 195 0.021
Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.021
Worm
rna export from nucleus GO:0006405 33 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
negative regulation of cell differentiation GO:0045596 171 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
regulation of transferase activity GO:0051338 355 0.019
camera type eye development GO:0043010 25 0.019
protein dna complex subunit organization GO:0071824 80 0.019
regulation of multicellular organism growth GO:0040014 8 0.019
Worm
regulation of neurogenesis GO:0050767 82 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.019
sensory organ development GO:0007423 52 0.019
positive regulation of chromatin silencing GO:0031937 3 0.019
Fly
negative regulation of developmental process GO:0051093 247 0.019
Worm
neuron apoptotic process GO:0051402 39 0.018
developmental growth GO:0048589 48 0.018
Worm
positive regulation of cellular component organization GO:0051130 376 0.018
Fly
regulation of cell motility GO:2000145 299 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.018
internal protein amino acid acetylation GO:0006475 101 0.018
ribonucleotide biosynthetic process GO:0009260 81 0.017
cell part morphogenesis GO:0032990 137 0.017
positive regulation of proteolysis GO:0045862 142 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
nuclear transport GO:0051169 179 0.017
histone exchange GO:0043486 3 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
organelle assembly GO:0070925 176 0.016
reproduction GO:0000003 63 0.016
Worm
response to nutrient levels GO:0031667 81 0.016
development of primary sexual characteristics GO:0045137 35 0.016
Worm
cellular response to dna damage stimulus GO:0006974 379 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
taxis GO:0042330 157 0.015
atp dependent chromatin remodeling GO:0043044 25 0.015
apoptotic signaling pathway GO:0097190 268 0.015
gamete generation GO:0007276 25 0.015
Worm
sister chromatid cohesion GO:0007062 24 0.015
viral life cycle GO:0019058 132 0.015
response to inorganic substance GO:0010035 127 0.015
regulation of neuron apoptotic process GO:0043523 35 0.015
regulation of chromatin assembly or disassembly GO:0001672 6 0.015
Fly
posttranscriptional gene silencing by rna GO:0035194 25 0.015
regulation of chromatin organization GO:1902275 56 0.015
Fly
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.014
Worm
dna replication independent nucleosome organization GO:0034724 27 0.014
ossification GO:0001503 121 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
response to oxygen containing compound GO:1901700 369 0.014
regulation of developmental growth GO:0048638 30 0.014
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
learning GO:0007612 11 0.013
Worm
maintenance of location GO:0051235 112 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
short term memory GO:0007614 1 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
nervous system development GO:0007399 293 0.013
Fly
epithelial cell proliferation GO:0050673 128 0.013
neuron death GO:0070997 65 0.013
meiotic cell cycle process GO:1903046 8 0.013
positive regulation of cell proliferation GO:0008284 301 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
positive regulation of heterochromatin assembly GO:0031453 1 0.012
Fly
cellular component morphogenesis GO:0032989 314 0.012
response to oxygen levels GO:0070482 100 0.012
actin filament based process GO:0030029 224 0.012
regulation of protein processing GO:0070613 150 0.012
multi organism reproductive process GO:0044703 54 0.012
Worm
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
response to abiotic stimulus GO:0009628 336 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.012
positive regulation of axon extension GO:0045773 4 0.012
regulation of centriole replication GO:0046599 7 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
dna alkylation GO:0006305 7 0.011
Fly
circulatory system development GO:0072359 262 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
regeneration GO:0031099 4 0.011
locomotory behavior GO:0007626 1 0.011
negative regulation of cell cycle phase transition GO:1901988 89 0.011
atp metabolic process GO:0046034 176 0.011
cellular response to lipid GO:0071396 127 0.011
cell division GO:0051301 168 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
regulation of myeloid cell differentiation GO:0045637 81 0.010
regulation of kinase activity GO:0043549 314 0.010
regulation of cellular component movement GO:0051270 334 0.010
multicellular organism growth GO:0035264 8 0.010
Worm
segmentation GO:0035282 4 0.010
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.010

CBX3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.013
inherited metabolic disorder DOID:655 242 0.013