|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.998
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.995
|
|
|
|
glandular epithelial cell development
|
GO:0002068 |
5 |
0.995
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.994
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.992
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.988
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.983
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.975
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.972
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.968
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.948
|
|
|
|
type b pancreatic cell differentiation
|
GO:0003309 |
5 |
0.948
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.945
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.917
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.916
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.916
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.913
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.899
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.897
|
|
|
|
positive regulation of cell cycle g2 m phase transition
|
GO:1902751 |
8 |
0.895
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.892
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.886
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.883
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.876
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.873
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.865
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.865
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.862
|
Zebrafish |
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.856
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.856
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.833
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.818
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.804
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.794
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.793
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.788
|
Fly |
|
|
positive regulation of g2 m transition of mitotic cell cycle
|
GO:0010971 |
8 |
0.786
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.775
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.773
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.763
|
Mouse |
|
|
glandular epithelial cell differentiation
|
GO:0002067 |
6 |
0.757
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.747
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.745
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.741
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.736
|
Mouse |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.718
|
Mouse |
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.717
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.714
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.712
|
Mouse Rat |
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.711
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.709
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.705
|
Worm |
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.690
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.681
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.665
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.662
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.659
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.655
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.653
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.651
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.633
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.628
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.627
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.622
|
Fly |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.616
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.615
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.600
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.597
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.591
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.581
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.579
|
|
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.578
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.577
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
22 |
0.574
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.571
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.567
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.562
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.562
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.559
|
Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.544
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.532
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.520
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.519
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.512
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.509
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.506
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.498
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.498
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.487
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.474
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.468
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.460
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.456
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.455
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.454
|
Rat |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.451
|
Mouse |
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.447
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.447
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.441
|
|
|
|
cell dedifferentiation
|
GO:0043697 |
1 |
0.440
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.433
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.430
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.427
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.424
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.417
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.407
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.407
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.404
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.400
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.394
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.392
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.389
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.386
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.385
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.385
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.384
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.383
|
|
|
|
regulation of cellular senescence
|
GO:2000772 |
13 |
0.382
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.382
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.381
|
Rat |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.378
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.373
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.370
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.364
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.363
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.363
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.358
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.354
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
5 |
0.353
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.346
|
Fly |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.343
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.335
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.329
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.325
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.317
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.313
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.310
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.310
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.310
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.308
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.301
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.293
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.292
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.290
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.289
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.289
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.288
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.280
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.279
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.273
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.265
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.262
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.258
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.257
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.253
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.245
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.244
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.243
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.238
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.237
|
Rat |
|
|
ossification
|
GO:0001503 |
121 |
0.234
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.234
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.234
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.232
|
|
|
|
growth
|
GO:0040007 |
202 |
0.230
|
Fly |
|
|
ovulation cycle process
|
GO:0022602 |
9 |
0.229
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.229
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.228
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.225
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.222
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.222
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.222
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.220
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.220
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.216
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.214
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.212
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.210
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.207
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.207
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.204
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.202
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.200
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.198
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.197
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.197
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.194
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.186
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.185
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.185
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.185
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.184
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.184
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.184
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.182
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.178
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.177
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.177
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.176
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.173
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.172
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.171
|
|
|
|
dedifferentiation
|
GO:0043696 |
1 |
0.170
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.169
|
Rat |
|
|
sensory perception
|
GO:0007600 |
103 |
0.167
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.166
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.166
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.166
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.164
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.163
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.163
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.160
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.160
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.158
|
|
|
|
endocrine pancreas development
|
GO:0031018 |
11 |
0.157
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.154
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.154
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.153
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.152
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.152
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.150
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.148
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.148
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.146
|
Mouse |
|
|
response to drug
|
GO:0042493 |
81 |
0.144
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.143
|
|
|
|
system process
|
GO:0003008 |
349 |
0.142
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.141
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.139
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.136
|
Mouse Rat |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.135
|
|
|
|
response to nutrient
|
GO:0007584 |
20 |
0.133
|
Rat |
|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
12 |
0.133
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.131
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.128
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.128
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.127
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.125
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.124
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.124
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.124
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.123
|
Rat |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.123
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.121
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.121
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.121
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.121
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.120
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.120
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.118
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.117
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.117
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.116
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.116
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.116
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.115
|
|
|
|
regulation of cell aging
|
GO:0090342 |
18 |
0.115
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.115
|
Rat |
|
|
regeneration
|
GO:0031099 |
4 |
0.114
|
Rat |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.113
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.112
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.110
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.110
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.110
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.110
|
|
|
|
negative regulation of cellular senescence
|
GO:2000773 |
5 |
0.109
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.109
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.109
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.107
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.106
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.105
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.105
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.104
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.103
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.102
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.102
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.102
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.101
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.101
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.100
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.098
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.095
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.095
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.095
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.094
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.094
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.093
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.093
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.091
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.090
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.088
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.088
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.088
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.088
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
0.087
|
|
|
|
ovulation cycle
|
GO:0042698 |
9 |
0.087
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.086
|
Mouse |
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
22 |
0.086
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.085
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.085
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.084
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.084
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.083
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.083
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.082
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.082
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.082
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.082
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.081
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.081
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.080
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.080
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.079
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.079
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.078
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.078
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.077
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.077
|
Worm |
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.077
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.077
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.077
|
Rat |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.077
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.077
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.076
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.076
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.076
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.076
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.076
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.076
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.074
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.074
|
|
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.074
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.073
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.073
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.073
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.073
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.073
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.072
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.072
|
Rat |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.071
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.071
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.071
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.069
|
Rat |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.069
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.069
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.069
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.069
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.069
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.068
|
|
|
|
pancreas development
|
GO:0031016 |
19 |
0.068
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.068
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.067
|
Rat |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.067
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.067
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.065
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.065
|
Rat |
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.065
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.065
|
Worm |
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.064
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.064
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.064
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.064
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.064
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.064
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.063
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.063
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.062
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.061
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.061
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
10 |
0.060
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.060
|
Rat |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.060
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.060
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.060
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.059
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.059
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.059
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.059
|
Rat |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.058
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.058
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
15 |
0.058
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.058
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.058
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.057
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.057
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.056
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.056
|
Worm |
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
27 |
0.055
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.055
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.055
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.055
|
|
|
|
neutral lipid catabolic process
|
GO:0046461 |
12 |
0.055
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.054
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.054
|
Rat |
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.054
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.054
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.053
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.053
|
|
|
|
female sex differentiation
|
GO:0046660 |
12 |
0.052
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.052
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.052
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.051
|
|
|
|
aging
|
GO:0007568 |
66 |
0.051
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.051
|
Rat |
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.050
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.050
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.050
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.050
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.050
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.050
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.050
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.050
|
Fly |
|
|
gonad development
|
GO:0008406 |
34 |
0.050
|
Rat |
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.049
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.049
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.049
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.049
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.049
|
|
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.049
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.049
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
36 |
0.048
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.048
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.048
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.048
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.048
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.048
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.047
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.047
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.047
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.047
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.047
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.046
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.046
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.046
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.046
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.046
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.046
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.046
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.045
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.045
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.045
|
|
|
|
regulation of glycogen metabolic process
|
GO:0070873 |
15 |
0.045
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.045
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.045
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.045
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.044
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.044
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.044
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.044
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.044
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.044
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.043
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.043
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.043
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.042
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.042
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.042
|
|
|
|
mating
|
GO:0007618 |
1 |
0.042
|
|
|
|
cellular polysaccharide biosynthetic process
|
GO:0033692 |
21 |
0.042
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.042
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.042
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.042
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
1 |
0.042
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.041
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.041
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.041
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.041
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.041
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.041
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.040
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.040
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.040
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.040
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.040
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.039
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.039
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.039
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.039
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.039
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.039
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.039
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.039
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.039
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.039
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.039
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.039
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.038
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.038
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.038
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.038
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.037
|
|
|
|
response to vitamin d
|
GO:0033280 |
10 |
0.037
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.037
|
|
