|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
3 |
0.978
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.977
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.967
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.953
|
Human Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.946
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.944
|
Human |
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.931
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.897
|
Human |
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
2 |
0.886
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.878
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.875
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.873
|
Human |
|
|
immune effector process
|
GO:0002252 |
159 |
0.868
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.863
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.862
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.856
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
2 |
0.848
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.845
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.833
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.828
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.828
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.825
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.823
|
Human |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.819
|
Human |
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.813
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.800
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.793
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.790
|
Human |
|
|
defense response to virus
|
GO:0051607 |
71 |
0.787
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.784
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.782
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.779
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.767
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.767
|
Human |
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.761
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.759
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.756
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.732
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.729
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.729
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.723
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.723
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
11 |
0.710
|
|
|
|
mature natural killer cell chemotaxis
|
GO:0035782 |
1 |
0.703
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.698
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.693
|
Mouse |
|
|
cd8 positive alpha beta t cell activation
|
GO:0036037 |
3 |
0.692
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.663
|
|
|
|
negative regulation of c c chemokine binding
|
GO:2001264 |
1 |
0.662
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.653
|
Human |
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.651
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.651
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.645
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.643
|
Mouse |
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.625
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.623
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.622
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.621
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.618
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.617
|
|
|
|
myeloid dendritic cell chemotaxis
|
GO:0002408 |
3 |
0.616
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.615
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.611
|
|
|
|
endoplasmic reticulum to cytosol transport
|
GO:1903513 |
13 |
0.610
|
Human |
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.600
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.591
|
Mouse |
|
|
negative regulation of cytokine production involved in immune response
|
GO:0002719 |
13 |
0.591
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.579
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.576
|
Human |
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.575
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.572
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.572
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.570
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.564
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.559
|
Human |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.558
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.553
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.552
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
2 |
0.545
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.544
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.533
|
|
|
|
granzyme b production
|
GO:0071613 |
1 |
0.529
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.528
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.526
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.519
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.516
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.513
|
|
|
|
interleukin 8 mediated signaling pathway
|
GO:0038112 |
2 |
0.505
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.505
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.499
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.496
|
Human |
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.493
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.487
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.485
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.481
|
|
|
|
negative regulation of t cell cytokine production
|
GO:0002725 |
4 |
0.480
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.476
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.476
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.476
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
16 |
0.471
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.467
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.461
|
Human |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.458
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.458
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.456
|
Human |
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.448
|
Human |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.442
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.439
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
2 |
0.435
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.426
|
|
|
|
cellular response to triacyl bacterial lipopeptide
|
GO:0071727 |
2 |
0.422
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.419
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.418
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.416
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.413
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.406
|
Human |
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.406
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
27 |
0.394
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.392
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.391
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.390
|
|
|
|
regulation of chemokine mediated signaling pathway
|
GO:0070099 |
6 |
0.390
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.389
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.389
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.388
|
|
|
|
eosinophil activation
|
GO:0043307 |
3 |
0.376
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.374
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.371
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.369
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.369
|
Human |
|
|
response to triacyl bacterial lipopeptide
|
GO:0071725 |
2 |
0.365
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.362
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.361
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.361
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.355
|
Human |
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.351
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.347
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.346
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.345
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
10 |
0.344
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.341
|
|
|
|
interferon alpha biosynthetic process
|
GO:0045349 |
4 |
0.340
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.338
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.336
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.335
|
Human |
|
|
peptide transport
|
GO:0015833 |
74 |
0.334
|
|
|
|
complement component c5a signaling pathway
|
GO:0038178 |
1 |
0.332
|
|
|
|
regulation of sensory perception of pain
|
GO:0051930 |
3 |
0.330
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.330
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.329
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.328
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.328
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.327
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.326
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.326
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.325
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
2 |
0.325
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.325
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.321
|
Human |
|
|
macrophage chemotaxis
|
GO:0048246 |
10 |
0.321
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.319
|
|
|
|
cd4 positive alpha beta t cell proliferation
|
GO:0035739 |
2 |
0.317
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.310
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.308
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
10 |
0.305
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.304
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.302
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.301
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.298
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.298
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.297
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.297
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.294
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.294
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.288
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.286
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.282
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.280
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.278
|
Human |
|
|
regulation of t helper 1 cell activation
|
GO:2000517 |
1 |
0.274
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.273
|
|
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.272
|
Human |
|
|
negative regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000562 |
1 |
0.272
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.271
|
Mouse |
|
|
negative regulation of biomineral tissue development
|
GO:0070168 |
8 |
0.270
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.269
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.265
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.264
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.261
|
|
|
|
negative regulation of lymphocyte migration
|
GO:2000402 |
4 |
0.261
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
8 |
0.261
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.258
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.252
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.251
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.251
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.248
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.245
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.243
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
7 |
0.240
|
Human |
|
|
serotonin transport
|
GO:0006837 |
3 |
0.238
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
13 |
0.237
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.235
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.232
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.229
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.228
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.228
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.228
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.227
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.227
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.225
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.223
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.223
|
|
|
|
negative regulation of chemokine mediated signaling pathway
|
GO:0070100 |
5 |
0.220
|
|
|
|
negative regulation of natural killer cell chemotaxis
|
GO:2000502 |
1 |
0.215
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.213
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
5 |
0.213
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.211
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.210
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.210
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.209
|
Mouse |
|
|
negative regulation of production of molecular mediator of immune response
|
GO:0002701 |
13 |
0.209
|
|
|
|
interleukin 10 production
|
GO:0032613 |
17 |
0.207
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.206
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.206
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.204
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.203
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.203
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.201
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
7 |
0.200
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.199
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.198
|
|
|
|
cell killing
|
GO:0001906 |
34 |
0.196
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.195
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.195
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.193
|
|
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
1 |
0.192
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.192
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.189
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.189
|
|
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
5 |
0.189
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.188
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.188
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
9 |
0.188
|
|
|
|
negative regulation of g protein coupled receptor protein signaling pathway
|
GO:0045744 |
18 |
0.188
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.187
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.185
|
|
|
|
serotonin secretion
|
GO:0001820 |
1 |
0.182
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.181
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
16 |
0.181
|
Human |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.180
|
Mouse |
|
|
regulation of interferon alpha biosynthetic process
|
GO:0045354 |
4 |
0.180
|
|
|
|
regulation of cell killing
|
GO:0031341 |
22 |
0.179
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.179
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.178
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.177
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.177
|
Human |
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.176
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.176
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.175
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.174
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.174
|
Human |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.174
|
Human |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.173
|
|
|
|
regulation of granzyme a production
|
GO:2000511 |
1 |
0.173
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.172
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.171
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.170
|
|
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.170
|
|
|
|
regulation of gamma delta t cell activation involved in immune response
|
GO:2001191 |
1 |
0.170
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.169
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.168
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.168
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.167
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.166
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.165
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.162
|
Human |
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.161
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.159
|
|
|
|
response to diacyl bacterial lipopeptide
|
GO:0071724 |
2 |
0.158
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.156
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.155
|
|
|
|
interferon gamma biosynthetic process
|
GO:0042095 |
8 |
0.155
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.155
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.154
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.153
|
|
|
|
type i interferon secretion
|
GO:0072641 |
1 |
0.153
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.152
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.152
|
Human |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.152
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.151
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.151
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.151
|
|
|
|
activation of phospholipase d activity
|
GO:0031584 |
3 |
0.148
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.148
|
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.147
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.147
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.147
|
|
|
|
positive regulation of granzyme b production
|
GO:0071663 |
1 |
0.145
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.144
|
Human |
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.144
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.144
|
|
|
|
negative regulation of lymphocyte chemotaxis
|
GO:1901624 |
2 |
0.144
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.144
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
19 |
0.144
|
|
|
|
positive regulation of cell cell adhesion mediated by integrin
|
GO:0033634 |
3 |
0.144
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.143
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.140
|
Human |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.140
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
14 |
0.139
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.138
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.138
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.137
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.136
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.136
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.136
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.134
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.134
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.134
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.132
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.132
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.132
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.132
|
|
|
|
positive regulation of homotypic cell cell adhesion
|
GO:0034112 |
4 |
0.132
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.132
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.132
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
4 |
0.131
|
|
|
|
complement receptor mediated signaling pathway
|
GO:0002430 |
3 |
0.130
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
10 |
0.130
|
Human |
|
|
phagocytosis recognition
|
GO:0006910 |
3 |
0.129
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.129
|
|
|
|
positive regulation of t cell chemotaxis
|
GO:0010820 |
7 |
0.128
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.127
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.125
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.125
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.125
|
|
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
3 |
0.124
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.123
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.122
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.122
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.121
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
12 |
0.120
|
|
|
|
negative regulation of viral genome replication
|
GO:0045071 |
35 |
0.120
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.119
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.119
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.119
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.118
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.117
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.115
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.113
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.112
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.112
|
|
|
|
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:2001189 |
1 |
0.112
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.110
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.110
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.110
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.110
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.110
|
|
|
|
regulation of c c chemokine binding
|
GO:2001263 |
1 |
0.110
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.109
|
|
|
|
establishment of lymphocyte polarity
|
GO:0001767 |
2 |
0.108
|
|
|
|
monocyte chemotaxis
|
GO:0002548 |
20 |
0.108
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.108
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.107
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.106
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.105
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.105
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
9 |
0.105
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.105
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.104
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.103
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.103
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.103
|
Human |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.102
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.102
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.101
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
41 |
0.101
|
Human |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.101
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.101
|
|
|
|
regulation of t cell chemotaxis
|
GO:0010819 |
7 |
0.101
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.100
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.100
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
25 |
0.100
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.099
|
|
|
|
establishment of t cell polarity
|
GO:0001768 |
2 |
0.099
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.098
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.098
|
Human |
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.097
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.097
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
8 |
0.096
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.095
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.094
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.094
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.094
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.094
|
|
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.093
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
1 |
0.092
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.092
|
|
|
|
t helper 1 cell activation
|
GO:0035711 |
1 |
0.092
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.091
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
8 |
0.091
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.091
|
Human |
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.090
|
Mouse |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.090
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.090
|
Human |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.089
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.089
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.088
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.088
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.088
|
Human |
|
|
granzyme a production
|
GO:0035746 |
1 |
0.087
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.087
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
17 |
0.086
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.086
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.086
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.085
|
|
|
|
positive regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000566 |
1 |
0.085
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.085
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.085
|
|
|
|
eosinophil chemotaxis
|
GO:0048245 |
8 |
0.085
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.084
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.084
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.083
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.083
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.082
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.082
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.082
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.082
|
|
|
|
positive regulation of granzyme a production
|
GO:2000513 |
1 |
0.081
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.081
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.081
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.081
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.081
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.081
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.080
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.080
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.079
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.079
|
|
|
|
negative regulation of t helper 1 cell activation
|
GO:2000518 |
1 |
0.079
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.078
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.078
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.078
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.077
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.077
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.077
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.077
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
16 |
0.077
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.076
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.076
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.076
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.076
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.075
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.075
|
Human |
|
|
negative regulation of myeloid cell apoptotic process
|
GO:0033033 |
4 |
0.075
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.075
|
|
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
8 |
0.074
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.074
|
Human |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.074
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.074
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.074
|
Human |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.073
|
|
|
|
cellular response to diacyl bacterial lipopeptide
|
GO:0071726 |
2 |
0.073
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
17 |
0.073
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.073
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.071
|
|
|
|
negative regulation of interleukin 10 production
|
GO:0032693 |
7 |
0.071
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.071
|
|
|
|
regulation of sensory perception
|
GO:0051931 |
3 |
0.071
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
2 |
0.070
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.070
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.070
|
Human |
|
|
regulation of cell cell adhesion mediated by integrin
|
GO:0033632 |
6 |
0.069
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.069
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.069
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.069
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.069
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.069
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.069
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.068
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.068
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.068
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.068
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.068
|
Human |
|
|
regulation of granzyme b production
|
GO:0071661 |
1 |
0.068
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.067
|
|
|
|
detection of diacyl bacterial lipopeptide
|
GO:0042496 |
2 |
0.067
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.067
|
Human |
|
|
positive regulation of cd8 positive alpha beta t cell activation
|
GO:2001187 |
1 |
0.067
|
|
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.066
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.066
|
|
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.066
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
4 |
0.066
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.065
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.065
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.065
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.065
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.064
|
|
|
|
astrocyte chemotaxis
|
GO:0035700 |
1 |
0.064
|
Human |
|
|
regulation of interferon gamma biosynthetic process
|
GO:0045072 |
8 |
0.064
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.064
|
|
|
|
calcium ion transport from endoplasmic reticulum to cytosol
|
GO:1903514 |
13 |
0.063
|
Human |
