|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.866
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.791
|
Rat |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.767
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.680
|
Rat |
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.670
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.652
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.645
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.627
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.617
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.612
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.576
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.552
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.530
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.525
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.521
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.519
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.511
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.482
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.455
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.445
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.444
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.416
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.413
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.413
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.407
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.401
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.396
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.395
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.393
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.382
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.380
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.380
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.377
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.376
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.376
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.368
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.365
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.361
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.359
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.354
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.354
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.352
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.352
|
|
|
|
negative regulation of production of molecular mediator of immune response
|
GO:0002701 |
13 |
0.339
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.337
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.336
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.332
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.328
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.326
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.324
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.323
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.320
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.312
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.312
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.310
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.297
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.294
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.281
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.279
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.274
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.272
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.269
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.266
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.254
|
|
|
|
negative regulation of neurological system process
|
GO:0031645 |
2 |
0.253
|
|
|
|
negative regulation of macrophage cytokine production
|
GO:0010936 |
3 |
0.236
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.232
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.231
|
Rat |
|
|
regulation of macrophage cytokine production
|
GO:0010935 |
4 |
0.231
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.231
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.225
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.224
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.221
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.213
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.206
|
|
|
|
complement receptor mediated signaling pathway
|
GO:0002430 |
3 |
0.197
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
20 |
0.195
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.189
|
Rat |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.183
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.180
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.180
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.180
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.178
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.177
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.176
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.176
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.173
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.171
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.171
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.171
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.168
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.167
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.162
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.160
|
Rat |
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.159
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.159
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.154
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.154
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.153
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.150
|
Rat |
|
|
immune effector process
|
GO:0002252 |
159 |
0.148
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.146
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.146
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.145
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.142
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.141
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.141
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.139
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.138
|
Rat |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.138
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.138
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.138
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.134
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.133
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.131
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.129
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.125
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.125
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.120
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.119
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.119
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.118
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.116
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.115
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.111
|
Rat |
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.111
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.111
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.111
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.109
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.109
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.106
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.105
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.104
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.103
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.102
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.099
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.097
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.094
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.094
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.094
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.093
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.093
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.093
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.093
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.092
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.091
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.091
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.090
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.089
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.089
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.088
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.087
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.087
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.087
|
Mouse |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.086
|
Rat |
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.086
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.085
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.084
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.084
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.084
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.083
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.082
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.081
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.081
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.080
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.079
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.079
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.077
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.077
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.075
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.075
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.075
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.074
|
|
|
|
cellular response to triacyl bacterial lipopeptide
|
GO:0071727 |
2 |
0.074
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.074
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.073
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.073
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.073
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.072
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.072
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.072
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.071
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.071
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.070
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.070
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.070
|
|
|
|
complement component c5a signaling pathway
|
GO:0038178 |
1 |
0.070
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.069
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.069
|
|
|
|
negative regulation of cytokine production involved in immune response
|
GO:0002719 |
13 |
0.068
|
|
|
|
macrophage cytokine production
|
GO:0010934 |
4 |
0.068
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.067
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.067
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.065
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.064
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.063
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.063
|
Mouse Rat |
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.062
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.061
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.061
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.061
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.061
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.060
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.060
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.060
|
|
|
|
lipopolysaccharide transport
|
GO:0015920 |
2 |
0.059
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.059
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.058
|
|
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
9 |
0.058
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.058
|
|
|
|
detection of biotic stimulus
|
GO:0009595 |
21 |
0.057
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.057
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.054
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.053
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.053
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.053
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.053
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.052
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.052
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.052
|
|
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
3 |
0.052
|
|
|
|
system process
|
GO:0003008 |
349 |
0.051
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.051
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.050
|
|
|
|
detection of external biotic stimulus
|
GO:0098581 |
19 |
0.050
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.049
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.049
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.048
|
|
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.048
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.048
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.047
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.047
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.046
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.046
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.046
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.046
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.046
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.046
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.046
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.045
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.045
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.045
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.045
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.045
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.045
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
18 |
0.045
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.045
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.044
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.044
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.044
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.044
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.044
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.043
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.043
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.043
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.043
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.042
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.042
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.041
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
17 |
0.040
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.040
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.040
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.040
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.040
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.040
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.040
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.039
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.039
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.039
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.039
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.039
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.039
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.039
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.039
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.038
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.038
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.038
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.038
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.038
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.038
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
10 |
0.038
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.038
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.038
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.037
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.037
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.037
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.037
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.037
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.037
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.036
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.036
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.036
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.036
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.036
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.036
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.035
|
|
|
|
rna destabilization
|
GO:0050779 |
1 |
0.035
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.035
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.035
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.035
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.035
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.035
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.035
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.034
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.034
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.034
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.034
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.034
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.034
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.034
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.034
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.034
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.034
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.033
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.033
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.033
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.033
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
20 |
0.033
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.033
|
|
|
|
response to diacyl bacterial lipopeptide
|
GO:0071724 |
2 |
0.033
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.032
|
Rat |
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.032
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.032
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.032
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.032
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.032
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.031
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.031
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.031
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.031
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.031
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.031
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.031
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.031
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.030
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.030
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
25 |
0.030
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.030
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.030
|
Rat |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.029
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.029
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.029
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.029
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.029
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.029
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
2 |
0.029
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.029
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.028
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.028
|
Rat |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.028
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.028
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.027
|
|
|
|
regulation of hair cycle
|
GO:0042634 |
10 |
0.027
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.027
|
Rat |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.027
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.027
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.027
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.027
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.027
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.027
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.027
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.026
|
|
|
|
regulation of myelination
|
GO:0031641 |
1 |
0.026
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.026
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.026
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.026
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.026
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.026
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.026
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.026
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.026
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.026
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.025
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.025
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.025
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.025
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.025
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.025
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.025
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.025
|
|
|
|
positive regulation of cell cell adhesion
|
GO:0022409 |
22 |
0.025
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.025
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.025
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.025
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.024
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.024
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.024
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.024
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.024
|
|
|
|
response to triacyl bacterial lipopeptide
|
GO:0071725 |
2 |
0.024
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.024
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.024
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.024
|
Rat |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.023
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.023
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.023
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.023
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.023
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.023
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.023
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.023
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.023
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.023
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.023
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.023
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.023
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.022
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.022
|
|
|
|
negative regulation of interleukin 6 production
|
GO:0032715 |
13 |
0.022
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.022
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.022
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.022
|
|
|
|
interleukin 12 production
|
GO:0032615 |
15 |
0.022
|
|
|
|
pulmonary valve formation
|
GO:0003193 |
1 |
0.022
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.022
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.022
|
|
|
|
positive regulation of tolerance induction
|
GO:0002645 |
2 |
0.022
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.022
|
|
|
|
tnfsf11 mediated signaling pathway
|
GO:0071847 |
2 |
0.022
|
|
|
|
regulation of collagen metabolic process
|
GO:0010712 |
15 |
0.021
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.021
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.021
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.021
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.021
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.021
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.021
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.021
|
Mouse |
|
|
leukocyte migration involved in inflammatory response
|
GO:0002523 |
2 |
0.021
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.020
|
|
|
|
positive regulation of hair follicle development
|
GO:0051798 |
3 |
0.020
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.020
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.020
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.020
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.020
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.020
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.020
|
|
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
3 |
0.020
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
15 |
0.020
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.020
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.020
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.020
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.020
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.020
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.020
|
|
|
|
regulation of tolerance induction
|
GO:0002643 |
4 |
0.020
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.019
|
|
|
|
growth
|
GO:0040007 |
202 |
0.019
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.019
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.019
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.019
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.019
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.019
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.019
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.018
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.018
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.018
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.018
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.018
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.018
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
2 |
0.018
|
|
|
|
regulation of complement activation lectin pathway
|
GO:0001868 |
2 |
0.018
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.018
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.018
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.018
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.018
|
|
|
|
response to lipoteichoic acid
|
GO:0070391 |
3 |
0.018
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.018
|
|
|
|
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:0002291 |
4 |
0.018
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.017
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.017
|
|
|
|
myeloid leukocyte cytokine production
|
GO:0061082 |
5 |
0.017
|
|
|
|
regulation of renal albumin absorption
|
GO:2000532 |
1 |
0.017
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.017
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.017
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.017
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.017
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.017
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.017
|
Rat |
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
14 |
0.017
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
16 |
0.017
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.017
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.017
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.017
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.017
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.017
|
Mouse |
|
|
cellular response to lipoteichoic acid
|
GO:0071223 |
3 |
0.017
|
|