Homo sapiens

214 known processes

CD74

CD74 molecule, major histocompatibility complex, class II invariant chain

(Aliases: II,DHLAG,Ia-GAMMA,HLADG)

CD74 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
peptide antigen assembly with mhc protein complex GO:0002501 4 0.999
negative regulation of antigen processing and presentation GO:0002578 5 0.999
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 4 0.997
Mouse
cytokine production GO:0001816 247 0.994
Mouse
peptide antigen assembly with mhc class ii protein complex GO:0002503 4 0.993
mononuclear cell proliferation GO:0032943 71 0.991
negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002581 3 0.988
regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002586 3 0.987
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 12 0.978
Mouse
leukocyte proliferation GO:0070661 74 0.976
chemokine c c motif ligand 11 production GO:0071954 1 0.975
antigen processing and presentation GO:0019882 33 0.974
Mouse
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 11 0.967
Mouse
cell activation GO:0001775 213 0.964
antigen processing and presentation of peptide antigen GO:0048002 18 0.959
Mouse
antigen processing and presentation of exogenous peptide antigen GO:0002478 4 0.956
Mouse
polysaccharide assembly with mhc class ii protein complex GO:0002506 2 0.954
regulation of t cell proliferation GO:0042129 42 0.932
t cell proliferation GO:0042098 45 0.926
lymphocyte proliferation GO:0046651 70 0.923
regulation of interleukin 10 secretion GO:2001179 4 0.921
myeloid dendritic cell chemotaxis GO:0002408 3 0.920
positive regulation of lymphocyte proliferation GO:0050671 46 0.909
t cell activation GO:0042110 99 0.907
Mouse
astrocyte chemotaxis GO:0035700 1 0.906
positive regulation of antigen processing and presentation GO:0002579 1 0.900
Mouse
negative regulation of neutrophil chemotaxis GO:0090024 2 0.890
mhc class ii protein complex assembly GO:0002399 4 0.882
mhc protein complex assembly GO:0002396 4 0.870
cellular protein complex assembly GO:0043623 188 0.868
leukocyte activation GO:0045321 164 0.866
interleukin 8 mediated signaling pathway GO:0038112 2 0.862
defense response GO:0006952 315 0.859
Mouse
positive regulation of immune system process GO:0002684 283 0.847
negative regulation of immune system process GO:0002683 136 0.841
Mouse
regulation of mononuclear cell proliferation GO:0032944 65 0.840
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.836
negative regulation of cell proliferation GO:0008285 228 0.824
positive regulation of lymphocyte activation GO:0051251 73 0.791
regulation of leukocyte proliferation GO:0070663 67 0.788
positive regulation of cell proliferation GO:0008284 301 0.782
antigen processing and presentation of exogenous antigen GO:0019884 4 0.778
Mouse
negative regulation of antigen processing and presentation of peptide antigen GO:0002584 3 0.776
cellular response to ammonium ion GO:0071242 4 0.767
hematopoietic or lymphoid organ development GO:0048534 186 0.764
Mouse
secretion GO:0046903 254 0.764
humoral immune response GO:0006959 49 0.763
immune response GO:0006955 307 0.760
Mouse
protein carbohydrate complex subunit organization GO:0071823 2 0.741
negative regulation of granulocyte chemotaxis GO:0071623 2 0.737
lymphocyte mediated immunity GO:0002449 48 0.726
Mouse
positive regulation of hormone secretion GO:0046887 25 0.723
positive regulation of cell activation GO:0050867 81 0.716
positive regulation of leukocyte proliferation GO:0070665 48 0.712
hemopoiesis GO:0030097 180 0.710
Mouse
regulation of lymphocyte activation GO:0051249 103 0.709
cellular response to cytokine stimulus GO:0071345 181 0.683
response to cytokine GO:0034097 232 0.674
lymphocyte activation GO:0046649 133 0.674
regulation of lymphocyte proliferation GO:0050670 64 0.667
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.655
positive regulation of t cell proliferation GO:0042102 33 0.638
cellular macromolecular complex assembly GO:0034622 324 0.634
neurological system process GO:0050877 163 0.628
cellular response to interferon gamma GO:0071346 24 0.626
positive regulation of t cell activation GO:0050870 54 0.622
Mouse
transmission of nerve impulse GO:0019226 11 0.599
detection of biotic stimulus GO:0009595 21 0.596
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.585
negative regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002587 2 0.583
inflammatory response to antigenic stimulus GO:0002437 4 0.580
regulation of cell activation GO:0050865 125 0.564
regulation of interferon gamma production GO:0032649 36 0.561
cellular homeostasis GO:0019725 196 0.561
regulation of t cell activation GO:0050863 77 0.558
Mouse
positive regulation of lymphocyte differentiation GO:0045621 13 0.557
Mouse
positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 3 0.552
regulation of leukocyte activation GO:0002694 115 0.544
cardiac muscle contraction GO:0060048 34 0.526
regulation of cell migration GO:0030334 289 0.520
Mouse
response to lipid GO:0033993 206 0.520
positive regulation of adaptive immune response GO:0002821 21 0.519
regulation of camp metabolic process GO:0030814 52 0.517
positive regulation of leukocyte activation GO:0002696 80 0.501
innate immune response GO:0045087 178 0.485
response to bacterium GO:0009617 144 0.480
hormone secretion GO:0046879 65 0.468
regulation of cytokine production GO:0001817 232 0.462
Mouse
response to external biotic stimulus GO:0043207 261 0.455
system process GO:0003008 349 0.427
negative regulation of cell activation GO:0050866 33 0.411
Mouse
secretion by cell GO:0032940 226 0.409
negative regulation of neutrophil migration GO:1902623 2 0.407
antigen processing and presentation of polysaccharide antigen via mhc class ii GO:0002505 2 0.405
positive regulation of immune response GO:0050778 159 0.390
Mouse
positive regulation of astrocyte chemotaxis GO:2000464 1 0.366
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.350
patterning of blood vessels GO:0001569 2 0.333
response to hexose GO:0009746 20 0.321
negative regulation of defense response GO:0031348 47 0.314
tissue regeneration GO:0042246 3 0.310
chemical homeostasis GO:0048878 306 0.298
cellular chemical homeostasis GO:0055082 180 0.282
interleukin 10 production GO:0032613 17 0.277
negative regulation of blood vessel morphogenesis GO:2000181 41 0.267
positive regulation of behavior GO:0048520 60 0.265
Mouse
positive regulation of interferon gamma production GO:0032729 26 0.252
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 16 0.251
regulation of leukocyte differentiation GO:1902105 61 0.248
Mouse
interleukin 4 production GO:0032633 7 0.247
cellular response to biotic stimulus GO:0071216 71 0.246
b cell mediated immunity GO:0019724 10 0.245
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.240
protein carbohydrate complex assembly GO:0065006 2 0.236
cyclic nucleotide metabolic process GO:0009187 82 0.236
t helper 1 type immune response GO:0042088 8 0.228
positive regulation of cellular component movement GO:0051272 181 0.223
Mouse
negative regulation of locomotion GO:0040013 118 0.219
negative regulation of leukocyte chemotaxis GO:0002689 5 0.217
regulation of bone mineralization GO:0030500 29 0.215
motor neuron axon guidance GO:0008045 2 0.211
sprouting angiogenesis GO:0002040 29 0.207
positive regulation of transport GO:0051050 336 0.206
regulation of immune response GO:0050776 201 0.205
Mouse
t cell selection GO:0045058 4 0.205
Mouse
response to oxygen containing compound GO:1901700 369 0.205
branching morphogenesis of an epithelial tube GO:0048754 19 0.203
regulation of anatomical structure size GO:0090066 101 0.199
regulation of defense response GO:0031347 154 0.197
glucose homeostasis GO:0042593 31 0.196
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.195
positive regulation of cell death GO:0010942 263 0.194
myeloid cell differentiation GO:0030099 117 0.194
regulation of angiogenesis GO:0045765 92 0.193
cellular response to molecule of bacterial origin GO:0071219 62 0.189
response to organic cyclic compound GO:0014070 204 0.188
regulation of calcium ion transport GO:0051924 79 0.187
regulation of antigen processing and presentation GO:0002577 6 0.180
Mouse
peptide secretion GO:0002790 51 0.178
positive thymic t cell selection GO:0045059 1 0.178
Mouse
negative regulation of response to external stimulus GO:0032102 83 0.175
regulation of locomotion GO:0040012 329 0.173
Mouse
negative regulation of homeostatic process GO:0032845 59 0.173
Mouse
positive regulation of cell cycle process GO:0090068 106 0.173
response to cholesterol GO:0070723 11 0.172
regulation of purine nucleotide metabolic process GO:1900542 264 0.171
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.167
Mouse
regulation of astrocyte chemotaxis GO:2000458 1 0.162
regulation of mapk cascade GO:0043408 262 0.156
erk1 and erk2 cascade GO:0070371 104 0.155
positive regulation of leukocyte differentiation GO:1902107 37 0.154
Mouse
vasculogenesis GO:0001570 8 0.151
regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002580 4 0.151
retinal ganglion cell axon guidance GO:0031290 2 0.150
positive regulation of t cell differentiation GO:0045582 11 0.149
Mouse
vesicle mediated transport GO:0016192 371 0.149
regulation of cell motility GO:2000145 299 0.149
Mouse
positive regulation of camp metabolic process GO:0030816 41 0.147
response to interferon gamma GO:0034341 39 0.143
cytokine secretion GO:0050663 64 0.143
sequestering of metal ion GO:0051238 24 0.142
immunoglobulin production GO:0002377 12 0.142
tissue migration GO:0090130 119 0.140
blood circulation GO:0008015 113 0.139
interferon gamma production GO:0032609 39 0.137
neuronal action potential GO:0019228 9 0.137
ameboidal type cell migration GO:0001667 135 0.133
cytokine mediated signaling pathway GO:0019221 109 0.131
cellular defense response GO:0006968 2 0.131
osteoclast differentiation GO:0030316 21 0.128
cellular component assembly involved in morphogenesis GO:0010927 73 0.128
regulation of chemotaxis GO:0050920 74 0.126
Mouse
sarcoplasmic reticulum calcium ion transport GO:0070296 13 0.117
cation transport GO:0006812 331 0.116
cell migration involved in gastrulation GO:0042074 1 0.114
positive regulation of developmental process GO:0051094 314 0.114
Mouse
divalent inorganic cation homeostasis GO:0072507 136 0.114
cellular response to lipid GO:0071396 127 0.114
cellular calcium ion homeostasis GO:0006874 117 0.113
regulation of anatomical structure morphogenesis GO:0022603 286 0.112
negative regulation of immune response GO:0050777 40 0.112
response to fungus GO:0009620 4 0.112
immune effector process GO:0002252 159 0.112
Mouse
cellular glucose homeostasis GO:0001678 11 0.112
muscle system process GO:0003012 81 0.111
response to wounding GO:0009611 168 0.109
sequestering of calcium ion GO:0051208 17 0.108
cation homeostasis GO:0055080 189 0.107
regulation of protein stability GO:0031647 87 0.106
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.106
regeneration GO:0031099 4 0.105
granulocyte migration GO:0097530 40 0.104
Mouse
positive regulation of insulin secretion GO:0032024 10 0.102
regulation of neuron differentiation GO:0045664 70 0.102
Human
immune system development GO:0002520 195 0.100
Mouse
cell projection organization GO:0030030 252 0.099
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.099
negative regulation of chemotaxis GO:0050922 13 0.099
cytosolic calcium ion transport GO:0060401 48 0.096
positive regulation of secretion by cell GO:1903532 108 0.092
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.092
response to biotic stimulus GO:0009607 276 0.091
camp mediated signaling GO:0019933 23 0.091
regulation of adaptive immune response GO:0002819 33 0.091
regulation of nucleotide metabolic process GO:0006140 269 0.091
positive regulation of leukocyte chemotaxis GO:0002690 38 0.090
Mouse
receptor metabolic process GO:0043112 81 0.089
endocytosis GO:0006897 159 0.087
endomembrane system organization GO:0010256 196 0.087
detection of external biotic stimulus GO:0098581 19 0.086
positive regulation of gliogenesis GO:0014015 4 0.086
cellular ion homeostasis GO:0006873 168 0.085
positive regulation of secretion GO:0051047 116 0.084
regulation of cell growth GO:0001558 135 0.081
regulation of behavior GO:0050795 82 0.081
Mouse
regulation of vasculature development GO:1901342 97 0.081
heart process GO:0003015 62 0.080
positive regulation of cytokinesis GO:0032467 29 0.080
negative regulation of dendritic cell differentiation GO:2001199 2 0.079
positive regulation of t helper 1 type immune response GO:0002827 4 0.079
positive t cell selection GO:0043368 2 0.078
Mouse
action potential GO:0001508 34 0.078
calcium ion homeostasis GO:0055074 122 0.077
immunoglobulin mediated immune response GO:0016064 10 0.077
Mouse
negative regulation of vasculature development GO:1901343 43 0.076
positive regulation of ion transport GO:0043270 87 0.076
monocyte chemotaxis GO:0002548 20 0.075
tissue homeostasis GO:0001894 63 0.075
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.075
regulation of cell cycle GO:0051726 393 0.074
response to molecule of bacterial origin GO:0002237 82 0.073
cellular cation homeostasis GO:0030003 163 0.072
cellular divalent inorganic cation homeostasis GO:0072503 128 0.072
positive regulation of leukocyte migration GO:0002687 46 0.072
Mouse
positive regulation of neutrophil chemotaxis GO:0090023 7 0.072
Mouse
regulation of erk1 and erk2 cascade GO:0070372 99 0.069
positive regulation of camp mediated signaling GO:0043950 10 0.068
bone mineralization GO:0030282 34 0.067
positive regulation of nucleotide metabolic process GO:0045981 230 0.067
regulation of camp mediated signaling GO:0043949 13 0.067
blood vessel development GO:0001568 172 0.066
signal transduction by phosphorylation GO:0023014 297 0.066
camp metabolic process GO:0046058 61 0.066
cellular response to glucocorticoid stimulus GO:0071385 4 0.066
regulation of cell differentiation GO:0045595 393 0.065
Human Mouse
cellular response to glucose stimulus GO:0071333 10 0.062
cellular response to nitrogen compound GO:1901699 144 0.062
inflammatory response GO:0006954 79 0.062
metal ion homeostasis GO:0055065 169 0.060
negative regulation of multicellular organismal process GO:0051241 317 0.060
Human Mouse
multicellular organismal signaling GO:0035637 34 0.059
regulation of biomineral tissue development GO:0070167 31 0.059
positive regulation of calcium ion transport GO:0051928 51 0.058
actomyosin structure organization GO:0031032 59 0.057
anatomical structure formation involved in morphogenesis GO:0048646 284 0.057
regulation of inflammatory response to antigenic stimulus GO:0002861 2 0.057
regulation of cell cycle process GO:0010564 266 0.056
negative regulation of developmental process GO:0051093 247 0.056
Human Mouse
regulation of cellular component size GO:0032535 82 0.055
positive regulation of cell division GO:0051781 59 0.055
regulation of complement activation lectin pathway GO:0001868 2 0.054
blood vessel endothelial cell migration GO:0043534 42 0.054
response to lipopolysaccharide GO:0032496 70 0.053
de novo protein folding GO:0006458 2 0.053
Mouse
metal ion transport GO:0030001 272 0.053
organelle assembly GO:0070925 176 0.053
chemokine production GO:0032602 32 0.053
Mouse
divalent inorganic cation transport GO:0072511 158 0.052
regulation of metal ion transport GO:0010959 120 0.051
detection of stimulus GO:0051606 85 0.050
plasma membrane organization GO:0007009 115 0.050
regulation of ossification GO:0030278 58 0.050
regulation of homeostatic process GO:0032844 121 0.050
Mouse
maintenance of location GO:0051235 112 0.050
morphogenesis of a branching epithelium GO:0061138 20 0.050
regulation of leukocyte chemotaxis GO:0002688 46 0.049
Mouse
endothelial cell migration GO:0043542 86 0.048
negative regulation of sequestering of calcium ion GO:0051283 41 0.048
tube development GO:0035295 125 0.048
digestive tract morphogenesis GO:0048546 56 0.047
response to alcohol GO:0097305 64 0.047
actin cytoskeleton organization GO:0030036 207 0.046
regulation of cell projection organization GO:0031344 107 0.046
Human
azole transport GO:0045117 4 0.046
endoplasmic reticulum to cytosol transport GO:1903513 13 0.046
single organism membrane organization GO:0044802 268 0.045
peptide transport GO:0015833 74 0.045
positive regulation of apoptotic process GO:0043065 246 0.045
cytosolic calcium ion homeostasis GO:0051480 89 0.045
response to abiotic stimulus GO:0009628 336 0.044
regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001188 2 0.044
epithelium development GO:0060429 227 0.044
regulation of myeloid cell differentiation GO:0045637 81 0.044
execution phase of apoptosis GO:0097194 32 0.043
negative regulation of programmed cell death GO:0043069 321 0.043
head development GO:0060322 108 0.042
response to glucose GO:0009749 19 0.042
regulation of calcium ion transport into cytosol GO:0010522 33 0.042
positive chemotaxis GO:0050918 33 0.042
response to hypoxia GO:0001666 96 0.042
positive regulation of peptide secretion GO:0002793 15 0.042
cell morphogenesis involved in differentiation GO:0000904 144 0.041
positive regulation of cell motility GO:2000147 177 0.040
Mouse
tissue morphogenesis GO:0048729 96 0.040
cell chemotaxis GO:0060326 112 0.039
Mouse
membrane organization GO:0061024 292 0.039
negative regulation of cell migration GO:0030336 102 0.039
positive regulation of mapk cascade GO:0043410 190 0.038
cellular response to hormone stimulus GO:0032870 125 0.038
divalent metal ion transport GO:0070838 152 0.038
heart contraction GO:0060047 62 0.038
receptor mediated endocytosis GO:0006898 84 0.038
neuron projection extension GO:1990138 14 0.038
muscle contraction GO:0006936 73 0.038
regulation of glial cell differentiation GO:0045685 3 0.037
behavior GO:0007610 112 0.036
Mouse
regulation of intracellular transport GO:0032386 195 0.036
humoral immune response mediated by circulating immunoglobulin GO:0002455 5 0.036
epithelial cell differentiation GO:0030855 141 0.035
hormone transport GO:0009914 68 0.035
digestive tract development GO:0048565 75 0.035
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.035
regulation of establishment of protein localization GO:0070201 242 0.034
cellular component morphogenesis GO:0032989 314 0.034
calcium ion transport into cytosol GO:0060402 48 0.034
epithelial cell development GO:0002064 34 0.034
digestive system development GO:0055123 75 0.034
cell growth GO:0016049 160 0.034
growth GO:0040007 202 0.033
positive regulation of granulocyte chemotaxis GO:0071624 9 0.033
Mouse
response to monosaccharide GO:0034284 20 0.033
post embryonic development GO:0009791 2 0.032
actin filament based process GO:0030029 224 0.032
wound healing GO:0042060 115 0.032
central nervous system development GO:0007417 123 0.032
endothelial cell proliferation GO:0001935 65 0.031
negative regulation of angiogenesis GO:0016525 39 0.031
cell morphogenesis GO:0000902 296 0.031
cellular metal ion homeostasis GO:0006875 146 0.031
regulation of response to wounding GO:1903034 101 0.031
nitrogen compound transport GO:0071705 191 0.031
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.030
anatomical structure homeostasis GO:0060249 100 0.030
regulation of hormone secretion GO:0046883 57 0.030
regulation of cytoplasmic transport GO:1903649 149 0.030
regulation of response to external stimulus GO:0032101 222 0.030
Mouse
regulation of cytokine secretion GO:0050707 57 0.030
lymphangiogenesis GO:0001946 7 0.029
regulation of protein transport GO:0051223 213 0.029
ion homeostasis GO:0050801 230 0.029
myeloid leukocyte migration GO:0097529 62 0.029
Mouse
response to corticosteroid GO:0031960 15 0.029
cyclic nucleotide mediated signaling GO:0019935 26 0.029
regulation of membrane potential GO:0042391 95 0.029
axon extension GO:0048675 13 0.029
regulation of cellular ketone metabolic process GO:0010565 50 0.028
receptor internalization GO:0031623 43 0.028
positive regulation of intracellular transport GO:0032388 104 0.028
axon ensheathment GO:0008366 6 0.028
gastrulation GO:0007369 51 0.028
leukocyte differentiation GO:0002521 98 0.028
Mouse
nervous system development GO:0007399 293 0.028
Human
ras protein signal transduction GO:0007265 73 0.028
negative regulation of biomineral tissue development GO:0070168 8 0.028
posttranscriptional regulation of gene expression GO:0010608 213 0.028
epithelial cell migration GO:0010631 119 0.028
positive regulation of cell development GO:0010720 92 0.027
negative regulation of leukocyte migration GO:0002686 14 0.027
angiogenesis GO:0001525 147 0.027
response to oxygen levels GO:0070482 100 0.027
regulation of ion transport GO:0043269 189 0.027
negative regulation of hydrolase activity GO:0051346 182 0.027
Human
regulation of cellular component movement GO:0051270 334 0.026
Mouse
cellular response to endogenous stimulus GO:0071495 336 0.026
regulation of growth GO:0040008 165 0.026
myeloid leukocyte differentiation GO:0002573 60 0.026
positive regulation of cell cycle GO:0045787 140 0.026
generation of neurons GO:0048699 152 0.026
Human
circulatory system process GO:0003013 113 0.025
negative regulation of epithelial cell proliferation GO:0050680 48 0.025
neutrophil chemotaxis GO:0030593 24 0.025
Mouse
regulation of sequestering of calcium ion GO:0051282 41 0.025
regulation of regulatory t cell differentiation GO:0045589 4 0.025
morphogenesis of a branching structure GO:0001763 21 0.025
second messenger mediated signaling GO:0019932 78 0.024
tube morphogenesis GO:0035239 95 0.024
negative regulation of cellular component movement GO:0051271 106 0.024
organ morphogenesis GO:0009887 147 0.024
negative regulation of cell motility GO:2000146 104 0.024
cellular response to organic cyclic compound GO:0071407 127 0.024
leukocyte mediated immunity GO:0002443 59 0.024
Mouse
protein oligomerization GO:0051259 173 0.024
negative regulation of cell death GO:0060548 345 0.024
carbohydrate homeostasis GO:0033500 31 0.024
oogenesis GO:0048477 2 0.023
organophosphate catabolic process GO:0046434 430 0.023
peptide hormone secretion GO:0030072 50 0.023
regulation of ion homeostasis GO:2000021 73 0.023
cytokinesis GO:0000910 96 0.023
positive regulation of homeostatic process GO:0032846 47 0.023
regulation of cell division GO:0051302 116 0.023
positive regulation of angiogenesis GO:0045766 51 0.022
multicellular organismal aging GO:0010259 3 0.022
negative regulation of behavior GO:0048521 15 0.022
response to other organism GO:0051707 261 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.022
epithelial tube morphogenesis GO:0060562 38 0.022
myeloid leukocyte activation GO:0002274 34 0.022
positive regulation of glial cell differentiation GO:0045687 2 0.022
negative regulation of t cell activation GO:0050868 18 0.022
Mouse
negative regulation of bone mineralization GO:0030502 7 0.022
response to steroid hormone GO:0048545 80 0.022
cell cell signaling GO:0007267 155 0.022
regulation of apoptotic signaling pathway GO:2001233 175 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
gliogenesis GO:0042063 21 0.021
cell projection morphogenesis GO:0048858 129 0.021
cell development GO:0048468 328 0.021
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.021
positive regulation of gtpase activity GO:0043547 166 0.021
epithelial cell proliferation GO:0050673 128 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
regulation of epithelial cell proliferation GO:0050678 113 0.020
protein catabolic process GO:0030163 325 0.020
purine ribonucleoside metabolic process GO:0046128 437 0.020
regulation of protein maturation GO:1903317 150 0.020
Human
nucleoside catabolic process GO:0009164 408 0.020
granulocyte activation GO:0036230 10 0.020
muscle cell differentiation GO:0042692 63 0.020
guanosine containing compound catabolic process GO:1901069 239 0.019
cellular response to organonitrogen compound GO:0071417 124 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
regulation of t helper 1 type immune response GO:0002825 5 0.019
regulation of cytokinesis GO:0032465 45 0.019
ossification GO:0001503 121 0.019
response to ammonium ion GO:0060359 7 0.019
purine containing compound catabolic process GO:0072523 411 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
negative regulation of ossification GO:0030279 21 0.019
myelination GO:0042552 6 0.019
response to dexamethasone GO:0071548 1 0.019
multicellular organismal homeostasis GO:0048871 67 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.018
regulation of protein secretion GO:0050708 86 0.018
cell part morphogenesis GO:0032990 137 0.018
leukocyte migration GO:0050900 107 0.018
Mouse
t cell differentiation in thymus GO:0033077 4 0.018
Mouse
negative regulation of catalytic activity GO:0043086 335 0.018
Human
cellular response to oxidative stress GO:0034599 85 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
regulation of secretion by cell GO:1903530 177 0.018
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.018
positive regulation of cell differentiation GO:0045597 211 0.018
Mouse
circulatory system development GO:0072359 262 0.017
lymph vessel morphogenesis GO:0036303 7 0.017
striated muscle cell development GO:0055002 27 0.017
regulation of leukocyte migration GO:0002685 63 0.017
Mouse
g protein coupled receptor signaling pathway GO:0007186 207 0.017
negative regulation of lymphocyte activation GO:0051250 24 0.017
Mouse
response to hormone GO:0009725 175 0.017
cell division GO:0051301 168 0.017
cardiovascular system development GO:0072358 262 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
positive regulation of myeloid cell differentiation GO:0045639 39 0.017
chemokine mediated signaling pathway GO:0070098 16 0.017
regulation of execution phase of apoptosis GO:1900117 11 0.017
regulation of endothelial cell proliferation GO:0001936 56 0.017
amine metabolic process GO:0009308 44 0.017
cellular protein catabolic process GO:0044257 261 0.016
developmental cell growth GO:0048588 18 0.016
neuron projection development GO:0031175 106 0.016
Human
positive regulation of osteoclast differentiation GO:0045672 9 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
protein tetramerization GO:0051262 47 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
regulation of interleukin 4 production GO:0032673 7 0.016
regulation of humoral immune response GO:0002920 11 0.016
cytoplasmic transport GO:0016482 379 0.016
regulation of neurogenesis GO:0050767 82 0.016
Human
granulocyte chemotaxis GO:0071621 37 0.015
Mouse
gtp catabolic process GO:0006184 237 0.015
regulation of granulocyte chemotaxis GO:0071622 16 0.015
Mouse
regulation of cell morphogenesis GO:0022604 153 0.015

CD74 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.995
hypersensitivity reaction disease DOID:0060056 25 0.960
nervous system disease DOID:863 431 0.300
neurodegenerative disease DOID:1289 102 0.300
central nervous system disease DOID:331 186 0.300
hypersensitivity reaction type ii disease DOID:417 19 0.213
musculoskeletal system disease DOID:17 223 0.142
connective tissue disease DOID:65 109 0.109
autoimmune disease of gastrointestinal tract DOID:0060031 4 0.047
celiac disease DOID:10608 4 0.047
brain disease DOID:936 73 0.035
disease of metabolism DOID:0014667 295 0.028
inherited metabolic disorder DOID:655 242 0.024
bone disease DOID:0080001 88 0.024