|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.962
|
Human |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.947
|
Human Mouse Rat |
|
|
cytokine production
|
GO:0001816 |
247 |
0.940
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.926
|
Mouse Rat |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.904
|
Human Mouse Rat |
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.892
|
Human Mouse Rat |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.871
|
Human |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.865
|
Human Mouse Rat |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.859
|
Rat |
|
|
immune response
|
GO:0006955 |
307 |
0.848
|
Human Mouse Rat |
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.847
|
Human Mouse Rat |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.847
|
Human Mouse Rat |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.837
|
Human Mouse Rat |
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.827
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.821
|
Human Mouse Rat |
|
|
immune system development
|
GO:0002520 |
195 |
0.814
|
Rat |
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.807
|
Human Mouse Rat |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.806
|
Human Mouse |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.799
|
Human Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.779
|
Human Mouse Rat |
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.751
|
Human Mouse Rat |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.746
|
Human Mouse Rat |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.743
|
Mouse Rat |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.734
|
Human Mouse Rat |
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
4 |
0.722
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.712
|
Human Mouse Rat |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.709
|
Rat |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.707
|
Human Mouse Rat |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.696
|
Human Mouse Rat |
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.693
|
Human |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.687
|
Human Mouse Rat |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.659
|
Mouse Rat |
|
|
response to other organism
|
GO:0051707 |
261 |
0.658
|
Mouse Rat |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.644
|
Rat |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.630
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.625
|
Human Mouse Rat |
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
8 |
0.591
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.571
|
Human Mouse Rat |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.569
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.547
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.527
|
Human Mouse Rat |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.526
|
Human Mouse Rat |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.517
|
Human Mouse Rat |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.510
|
Rat |
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.509
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.506
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.491
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.483
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.479
|
Human Mouse Rat |
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.469
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.467
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.466
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.435
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.432
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.425
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.425
|
Human Mouse Rat |
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.424
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.416
|
Human Mouse Rat |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.390
|
Human Mouse Rat |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.389
|
Rat |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.373
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.364
|
Rat |
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.361
|
Human |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.331
|
Human |
|
|
interferon alpha biosynthetic process
|
GO:0045349 |
4 |
0.327
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.326
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.323
|
Rat |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.323
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.315
|
Rat |
|
|
interleukin 8 mediated signaling pathway
|
GO:0038112 |
2 |
0.310
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.310
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
4 |
0.301
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.296
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.295
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.284
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
2 |
0.283
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.282
|
Rat |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.273
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.262
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.250
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.248
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.240
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.237
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.226
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.225
|
Human Mouse |
|
|
response to lipid
|
GO:0033993 |
206 |
0.225
|
Rat |
|
|
protein secretion
|
GO:0009306 |
98 |
0.224
|
Human |
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.220
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.218
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.216
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.208
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.206
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.203
|
Human |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.201
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.196
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.195
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.190
|
Human |
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
16 |
0.184
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.183
|
|
|
|
positive regulation of mitosis
|
GO:0045840 |
25 |
0.183
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.182
|
Human Mouse |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.181
|
|
|
|
cellular response to triacyl bacterial lipopeptide
|
GO:0071727 |
2 |
0.179
|
|
|
|
serotonin secretion
|
GO:0001820 |
1 |
0.178
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.175
|
Rat |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.174
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.172
|
Human Mouse Rat |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.171
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.169
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.165
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.165
|
Human |
|
|
interleukin 12 secretion
|
GO:0072610 |
1 |
0.162
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.156
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
2 |
0.155
|
|
|
|
chemokine c c motif ligand 21 signaling pathway
|
GO:0038116 |
1 |
0.155
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.155
|
|
|
|
myeloid dendritic cell chemotaxis
|
GO:0002408 |
3 |
0.155
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.154
|
|
|
|
type i interferon secretion
|
GO:0072641 |
1 |
0.151
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.151
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.147
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.146
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.145
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.143
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.143
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.141
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.140
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.140
|
Rat |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.140
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.139
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.138
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.135
|
Rat |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.131
|
Mouse Rat |
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.127
|
|
|
|
negative regulation of interferon beta production
|
GO:0032688 |
4 |
0.127
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.127
|
Mouse Rat |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.125
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.124
|
Rat |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.123
|
Human |
|
|
regulation of gamma delta t cell activation involved in immune response
|
GO:2001191 |
1 |
0.121
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.121
|
|
|
|
serotonin transport
|
GO:0006837 |
3 |
0.120
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.117
|
Rat |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.116
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.114
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.109
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.108
|
Rat |
|
|
regulation of interferon alpha biosynthetic process
|
GO:0045354 |
4 |
0.106
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.104
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.104
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
11 |
0.099
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.099
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.098
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.097
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.097
|
Rat |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.097
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.096
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.096
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.096
|
Mouse Rat |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.095
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.095
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.094
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.092
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.092
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.089
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
5 |
0.088
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.088
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.087
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.087
|
Mouse Rat |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.086
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.085
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.084
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.083
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.082
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.081
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.081
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.081
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.081
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.080
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.080
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
6 |
0.079
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.079
|
|
|
|
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:2001189 |
1 |
0.076
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.075
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.074
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.073
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.073
|
Human |
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.072
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.072
|
|
|
|
negative regulation of cd8 positive alpha beta t cell activation
|
GO:2001186 |
1 |
0.072
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.071
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.069
|
|
|
|
complement receptor mediated signaling pathway
|
GO:0002430 |
3 |
0.069
|
|
|
|
negative regulation of mononuclear cell proliferation
|
GO:0032945 |
15 |
0.068
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.068
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
2 |
0.068
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.068
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.068
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.068
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.067
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.067
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.067
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.067
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.067
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.067
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.066
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.066
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.065
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.065
|
Human |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.065
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.065
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.064
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.064
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.064
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.062
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.061
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
2 |
0.061
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.061
|
|
|
|
negative regulation of dendritic cell apoptotic process
|
GO:2000669 |
3 |
0.061
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.060
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.060
|
Rat |
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.058
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.058
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.058
|
Rat |
|
|
negative regulation of cytokine production involved in immune response
|
GO:0002719 |
13 |
0.058
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.057
|
|
|
|
antigen processing and presentation of lipid antigen via mhc class ib
|
GO:0048003 |
1 |
0.057
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
8 |
0.057
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.056
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.056
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.056
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.056
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
24 |
0.055
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.055
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.055
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.055
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.055
|
Mouse |
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.054
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.054
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.054
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.053
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.053
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.053
|
|
|
|
interferon gamma biosynthetic process
|
GO:0042095 |
8 |
0.053
|
Human |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.053
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.053
|
Mouse |
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.052
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.052
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.052
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.051
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.050
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.050
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.050
|
|
|
|
astrocyte chemotaxis
|
GO:0035700 |
1 |
0.050
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.050
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.049
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.049
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
4 |
0.048
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.048
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.048
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.048
|
Human |
|
|
positive regulation of calcium ion transport into cytosol
|
GO:0010524 |
20 |
0.048
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.047
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.047
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.047
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.047
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.046
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.046
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.046
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.046
|
|
|
|
cd8 positive alpha beta t cell activation
|
GO:0036037 |
3 |
0.046
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.045
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.045
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.045
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.045
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.045
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
2 |
0.045
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.045
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.045
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.044
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.044
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.044
|
Rat |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.043
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
4 |
0.043
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.043
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.043
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.042
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.041
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.041
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.041
|
|
|
|
complement component c5a signaling pathway
|
GO:0038178 |
1 |
0.041
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.040
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.040
|
Rat |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.040
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.040
|
Rat |
|
|
response to wounding
|
GO:0009611 |
168 |
0.040
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.040
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.040
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.039
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.039
|
|
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
3 |
0.038
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.038
|
Rat |
|
|
endocytosis
|
GO:0006897 |
159 |
0.038
|
|
|
|
regulation of interferon beta secretion
|
GO:0035547 |
1 |
0.037
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
4 |
0.037
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.037
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.037
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.037
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.037
|
|
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.036
|
|
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
3 |
0.036
|
|
|
|
chemokine c c motif ligand 11 production
|
GO:0071954 |
1 |
0.036
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.036
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.036
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.035
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.035
|
|
|
|
eosinophil activation
|
GO:0043307 |
3 |
0.035
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.035
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.035
|
|
|
|
negative regulation of bone mineralization
|
GO:0030502 |
7 |
0.035
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.035
|
|
|
|
type i interferon production
|
GO:0032606 |
27 |
0.035
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.035
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.034
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.034
|
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
15 |
0.034
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.034
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.034
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.034
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.033
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.033
|
Human |
|
|
regulation of astrocyte chemotaxis
|
GO:2000458 |
1 |
0.033
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.033
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.033
|
Human |
|
|
chemokine c c motif ligand 19 signaling pathway
|
GO:0038115 |
1 |
0.033
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.033
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.033
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.032
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.032
|
Human |
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.032
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.032
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.032
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.032
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.032
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.032
|
|
|
|
interleukin 10 production
|
GO:0032613 |
17 |
0.032
|
Human |
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
1 |
0.032
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.031
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.031
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
17 |
0.031
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.031
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.031
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.031
|
|
|
|
regulation of transforming growth factor beta secretion
|
GO:2001201 |
1 |
0.031
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.031
|
|
|
|
positive regulation of astrocyte chemotaxis
|
GO:2000464 |
1 |
0.031
|
|
|
|
camp mediated signaling
|
GO:0019933 |
23 |
0.031
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.031
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.030
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.030
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.030
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.030
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.030
|
|
|
|
regulation of dendritic cell differentiation
|
GO:2001198 |
3 |
0.030
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.030
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.030
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.030
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.030
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.030
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.030
|
Human |
|
|
lipoxygenase pathway
|
GO:0019372 |
4 |
0.030
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.030
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.030
|
|
|
|
negative regulation of interleukin 12 secretion
|
GO:2001183 |
1 |
0.029
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.029
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.029
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
41 |
0.029
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
16 |
0.029
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.028
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.028
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.028
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.028
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.028
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.028
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.028
|
|
|
|
response to diacyl bacterial lipopeptide
|
GO:0071724 |
2 |
0.027
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.027
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.027
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.027
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.027
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.027
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.027
|
|
|
|
regulation of eosinophil activation
|
GO:1902566 |
2 |
0.027
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.027
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
10 |
0.026
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.026
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.026
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.026
|
|
|
|
sarcoplasmic reticulum calcium ion transport
|
GO:0070296 |
13 |
0.026
|
|
|
|
negative regulation of eosinophil activation
|
GO:1902567 |
1 |
0.026
|
|
|
|
cellular response to bacterial lipoprotein
|
GO:0071220 |
3 |
0.026
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.026
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.026
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.026
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
11 |
0.026
|
|
|
|
negative regulation of interleukin 10 production
|
GO:0032693 |
7 |
0.026
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.025
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.025
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.025
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.025
|
Human |
|
|
monocyte chemotaxis
|
GO:0002548 |
20 |
0.025
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.025
|
|
|
|
response to triacyl bacterial lipopeptide
|
GO:0071725 |
2 |
0.025
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.025
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
15 |
0.025
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.025
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.025
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.025
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.025
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.025
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.024
|
|
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
2 |
0.024
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.024
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.024
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.024
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.024
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.024
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.024
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.024
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.024
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.024
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.024
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.024
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.024
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.023
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.023
|
|
|
|
negative regulation of dendritic cell differentiation
|
GO:2001199 |
2 |
0.023
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.023
|
Rat |
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.023
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.023
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.023
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.023
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.023
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.023
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.023
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.023
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.023
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
2 |
0.023
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.023
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.022
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.022
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.022
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.022
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.022
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.022
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.022
|
|
|
|
regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:2001188 |
2 |
0.022
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.022
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.022
|
|
|
|
interferon beta secretion
|
GO:0035546 |
1 |
0.022
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
16 |
0.022
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.022
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.022
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.021
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.021
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.021
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.021
|
|
|
|
regulatory t cell differentiation
|
GO:0045066 |
5 |
0.021
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.021
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.021
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.021
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.021
|
|
|
|
gamma delta t cell activation involved in immune response
|
GO:0002290 |
1 |
0.021
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.021
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.021
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.021
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.021
|
|
|
|
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:0002291 |
4 |
0.021
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.021
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.021
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.021
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.021
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.021
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.021
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.021
|
|
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
4 |
0.021
|
|
|
|
negative regulation of osteoclast development
|
GO:2001205 |
1 |
0.020
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.020
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.020
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.020
|
|
