|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.975
|
Human Zebrafish Worm Fly |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.935
|
Human Zebrafish Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.930
|
Human Zebrafish Rat Fly |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.926
|
Human Zebrafish Rat Fly |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.921
|
Worm Fly |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.884
|
Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.848
|
Human Zebrafish Worm Fly |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.822
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.820
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.765
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.732
|
Fly |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.727
|
Zebrafish |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.726
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.725
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.717
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.701
|
Human Fly |
|
|
centrosome organization
|
GO:0051297 |
58 |
0.685
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.650
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.614
|
Worm Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.611
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.591
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.577
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.557
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.541
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.529
|
Human Zebrafish |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.524
|
Worm Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.505
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.498
|
Human Zebrafish Rat Worm Fly |
|
|
endocytosis
|
GO:0006897 |
159 |
0.482
|
Worm |
|
|
tube development
|
GO:0035295 |
125 |
0.479
|
Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.479
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.477
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.471
|
Human Zebrafish Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.464
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.462
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.446
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.443
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.440
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.437
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.427
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.426
|
|
|
|
regulation of centrosome cycle
|
GO:0046605 |
15 |
0.420
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.412
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.402
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.398
|
Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.395
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.383
|
Worm Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.377
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.374
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.373
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.372
|
Fly |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.353
|
Zebrafish |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.343
|
Human Zebrafish Rat Fly |
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.334
|
Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.332
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.329
|
Worm |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.320
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.316
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.314
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.314
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.311
|
Worm Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.311
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.300
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.287
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.277
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.265
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.264
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.263
|
Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.259
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.258
|
Worm Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.257
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.256
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.254
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.243
|
Fly |
|
|
spindle assembly
|
GO:0051225 |
29 |
0.241
|
Fly |
|
|
nuclear division
|
GO:0000280 |
128 |
0.233
|
Worm Fly |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.229
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.225
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.216
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.215
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.215
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.213
|
|
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.205
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.201
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.194
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.192
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.192
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.191
|
|
|
|
regulation of centrosome duplication
|
GO:0010824 |
14 |
0.186
|
|
|
|
dna replication initiation
|
GO:0006270 |
6 |
0.180
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.179
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.175
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.171
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.170
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.157
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.153
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.150
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.147
|
|
|
|
centriole assembly
|
GO:0098534 |
14 |
0.146
|
Fly |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.140
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.139
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.132
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.132
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.132
|
Rat Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.131
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.131
|
Zebrafish Worm Fly |
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.131
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.129
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.129
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.126
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.123
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.122
|
Fly |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.121
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.119
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.119
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.117
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.114
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.113
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.112
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.112
|
|
|
|
centriole replication
|
GO:0007099 |
13 |
0.109
|
Fly |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.107
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.107
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.107
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.107
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.105
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.105
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.104
|
Fly |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.102
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.102
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.101
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.098
|
Human |
|
|
kidney development
|
GO:0001822 |
53 |
0.097
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.096
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.096
|
Human |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.095
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.094
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.093
|
Worm |
|
|
oocyte development
|
GO:0048599 |
1 |
0.092
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.091
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.090
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.089
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.088
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.088
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.087
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.085
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.082
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.082
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.081
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.081
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.079
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.077
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.077
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.074
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.072
|
Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.071
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.070
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.069
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.069
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.069
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.069
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.068
|
Fly |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.067
|
Rat |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.067
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.067
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.065
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.065
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.063
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.062
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.062
|
Worm |
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.062
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.062
|
Worm |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.061
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.060
|
Human Worm |
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.060
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.060
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.060
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.059
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.058
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.058
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.057
|
|
|
|
growth
|
GO:0040007 |
202 |
0.057
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.056
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
0.055
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.054
|
Fly |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.054
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.053
|
Worm Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.053
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.052
|
Fly |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.052
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.052
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.051
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.051
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.051
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.050
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.050
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.049
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.048
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.048
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.048
|
Human |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.047
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.047
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.046
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.045
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.045
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.044
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.044
|
Worm Fly |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.044
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.044
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.044
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.043
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.043
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.043
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.042
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.042
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.042
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.042
|
|
|
|
glomerular epithelial cell development
|
GO:0072310 |
3 |
0.041
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.041
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.040
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.040
|
Fly |
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.039
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.039
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.039
|
Fly |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.039
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.039
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.038
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.037
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.037
|
Zebrafish |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.037
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.036
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.036
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.036
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.036
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.036
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.036
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.035
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.035
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.035
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
15 |
0.035
|
Fly |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.035
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.035
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.035
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.034
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
24 |
0.034
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.034
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.034
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.033
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.033
|
Fly |
|
|
reproductive process
|
GO:0022414 |
106 |
0.033
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.032
|
|
|
|
histone threonine phosphorylation
|
GO:0035405 |
7 |
0.031
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.031
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.030
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.030
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.030
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.029
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.029
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.029
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.029
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.028
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.028
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.028
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.028
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.027
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.027
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.027
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.027
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.027
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.027
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.026
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.026
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.026
|
|
|
|
metanephros morphogenesis
|
GO:0003338 |
9 |
0.026
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.025
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
22 |
0.025
|
Zebrafish |
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.025
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.025
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.024
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.024
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.024
|
|
|
|
lung cell differentiation
|
GO:0060479 |
1 |
0.024
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.024
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.024
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.024
|
|
|
|
aging
|
GO:0007568 |
66 |
0.024
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.024
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.024
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.024
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.024
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.023
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.023
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.023
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.023
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.023
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.023
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.023
|
Human Worm Fly |
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.023
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.022
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.022
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.022
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.022
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.022
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.022
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.022
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.021
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.021
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.021
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.021
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.020
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.020
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.020
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.020
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.020
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.020
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.020
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.020
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.020
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.019
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.019
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.019
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.019
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.019
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.019
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.019
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.019
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.019
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.019
|
Worm |
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.019
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.019
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.019
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.019
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.018
|
Fly |
|
|
response to drug
|
GO:0042493 |
81 |
0.018
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.018
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.018
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.018
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.018
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.018
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.017
|
|
|
|
regulation of cell diameter
|
GO:0060305 |
1 |
0.017
|
Fly |
|
|
dna geometric change
|
GO:0032392 |
32 |
0.017
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.017
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.017
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.017
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.017
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.017
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.017
|
|
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.017
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.017
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.017
|
Human |
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.016
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.016
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.016
|
|
|
|
spindle checkpoint
|
GO:0031577 |
26 |
0.016
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.016
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.016
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.016
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.016
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.016
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.015
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.015
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.015
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.015
|
Worm Fly |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.014
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.014
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.014
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.014
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.014
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.014
|
Rat |
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.014
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.014
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.014
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.014
|
|
|
|
epithelial cell differentiation involved in kidney development
|
GO:0035850 |
9 |
0.014
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
0.014
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.013
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.013
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.013
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.013
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.013
|
|
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
1 |
0.013
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.013
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.013
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.013
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.013
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.013
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.013
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.013
|
|
|
|
lung development
|
GO:0030324 |
20 |
0.013
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.013
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.013
|
Fly |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.013
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.013
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.012
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.012
|
Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.012
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.012
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.012
|
|
|
|
negative regulation of tor signaling
|
GO:0032007 |
11 |
0.012
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.012
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.012
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.012
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.012
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.012
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.012
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.012
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.012
|
|
|
|
dna duplex unwinding
|
GO:0032508 |
30 |
0.012
|
|
|
|
mitotic sister chromatid cohesion
|
GO:0007064 |
12 |
0.011
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.011
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.011
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.011
|
|
|
|
chromosome condensation
|
GO:0030261 |
15 |
0.011
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.011
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.011
|
|
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.011
|
Human |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.011
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.011
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.011
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.011
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.011
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.011
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.011
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.011
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.011
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.011
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.011
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.011
|
|
|
|
glomerular parietal epithelial cell differentiation
|
GO:0072139 |
3 |
0.011
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.011
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.011
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.010
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.010
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.010
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.010
|
|
|
|
system process
|
GO:0003008 |
349 |
0.010
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.010
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.010
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.010
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.010
|
|
