|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.910
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.770
|
Worm |
|
|
neuroblast division
|
GO:0055057 |
1 |
0.743
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.737
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.736
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.686
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.671
|
Mouse Fly |
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.617
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.557
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.555
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.552
|
Mouse |
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.533
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.508
|
Mouse Rat Worm Fly |
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.492
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.490
|
Mouse |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.457
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.426
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.414
|
Fly |
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.392
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.379
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.364
|
Worm |
|
|
nucleus localization
|
GO:0051647 |
1 |
0.356
|
|
|
|
growth
|
GO:0040007 |
202 |
0.351
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.342
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.340
|
Fly |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.337
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.337
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.332
|
Worm Fly |
|
|
nuclear division
|
GO:0000280 |
128 |
0.332
|
Mouse Rat Worm Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.327
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.327
|
Mouse |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.326
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.318
|
Worm Fly |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.302
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.300
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.299
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.299
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.288
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.287
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.281
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.280
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.269
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.268
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.267
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.256
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.255
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.254
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.247
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.246
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.246
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.243
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.241
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.235
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.234
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.230
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.230
|
Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.229
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.226
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.224
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.223
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.223
|
|
|
|
regulation of cell diameter
|
GO:0060305 |
1 |
0.220
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.215
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.212
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.207
|
Worm Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.207
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.207
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.206
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.203
|
Rat |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.202
|
Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.201
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.200
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.197
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.172
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.169
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.169
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.166
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.166
|
|
|
|
regulation of peptidyl serine dephosphorylation
|
GO:1902308 |
2 |
0.161
|
|
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.159
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.155
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.152
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.152
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.150
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.148
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.147
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.146
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
187 |
0.146
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.140
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.139
|
Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.137
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.136
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.127
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.126
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.126
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.125
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.120
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.120
|
Mouse |
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.120
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.119
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.116
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.114
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.113
|
Mouse |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.113
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.113
|
Mouse |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.113
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.111
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.108
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.108
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.107
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.104
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.104
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.102
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.101
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.100
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.100
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.100
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.099
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.097
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.095
|
Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.094
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.094
|
|
|
|
membrane depolarization during action potential
|
GO:0086010 |
10 |
0.092
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.091
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.090
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.088
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.086
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.086
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.084
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.084
|
Zebrafish Worm Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.084
|
|
|
|
single fertilization
|
GO:0007338 |
11 |
0.084
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.083
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.082
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.082
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.081
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.081
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.081
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.080
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.079
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.077
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.076
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.076
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.074
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.074
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.074
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.073
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.072
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.071
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.071
|
Human Zebrafish Rat Fly |
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.071
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.070
|
Mouse |
|
|
organelle localization
|
GO:0051640 |
84 |
0.068
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.068
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.068
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.067
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.067
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.066
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.066
|
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
0.065
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.065
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.065
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.065
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.063
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.063
|
Fly |
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.063
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.063
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.063
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.062
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.061
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.061
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.061
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.060
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.060
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.059
|
Mouse |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.059
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.059
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.058
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.058
|
Fly |
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.058
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.057
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.057
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.057
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.057
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.057
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.056
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.056
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.055
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.055
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.054
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.054
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.054
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.053
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.053
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.053
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.053
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.053
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.052
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.052
|
|
|
|
head development
|
GO:0060322 |
108 |
0.052
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.051
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.051
|
Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.050
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.050
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.050
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.049
|
|
|
|
specification of axis polarity
|
GO:0065001 |
1 |
0.048
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.048
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.048
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.048
|
Worm |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.048
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.047
|
Fly |
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.047
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.047
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.047
|
Human Zebrafish Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.047
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.047
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.047
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.047
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.047
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.046
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.045
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.045
|
Fly |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.045
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.045
|
|
|
|
negative regulation of peptidyl serine dephosphorylation
|
GO:1902309 |
1 |
0.044
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.043
|
|
|
|
system process
|
GO:0003008 |
349 |
0.043
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.043
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.042
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.042
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.042
|
Mouse |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.042
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.041
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.041
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.041
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.041
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.041
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.040
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.040
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.040
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.039
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.039
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.039
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.039
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.039
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.039
|
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.038
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.038
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.037
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.037
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.037
|
Zebrafish |
|
|
glucocorticoid catabolic process
|
GO:0006713 |
1 |
0.037
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.037
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.037
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.036
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.036
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.036
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.036
|
Mouse Worm Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.036
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.036
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.036
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.036
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.036
|
|
|
|
glomerular epithelial cell development
|
GO:0072310 |
3 |
0.036
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.035
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.035
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.035
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.035
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.035
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.035
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.035
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.035
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.034
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.034
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.034
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.034
|
|
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
0.034
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.034
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.034
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.034
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.034
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.033
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.033
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.033
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.033
|
Worm |
|
|
action potential
|
GO:0001508 |
34 |
0.033
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.033
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.033
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.033
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.033
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.033
|
Worm |
|
|
developmental growth
|
GO:0048589 |
48 |
0.033
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.033
|
Human Zebrafish Fly |
|
|
steroid catabolic process
|
GO:0006706 |
10 |
0.033
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.032
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.032
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.032
|
|
|
|
lung cell differentiation
|
GO:0060479 |
1 |
0.032
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.032
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.032
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.032
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.031
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.031
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.031
|
|
|
|
dna replication initiation
|
GO:0006270 |
6 |
0.031
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.030
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.030
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.030
|
Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.030
|
|
|
|
glucocorticoid metabolic process
|
GO:0008211 |
10 |
0.030
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.030
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.029
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.029
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.029
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.029
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.029
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.029
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.029
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.029
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.028
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.028
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.028
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.028
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.028
|
Worm Fly |
|
|
microtubule anchoring
|
GO:0034453 |
24 |
0.028
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.027
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.027
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.027
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.027
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.027
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.027
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.027
|
Mouse |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.027
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.027
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.027
|
Mouse Worm Fly |
|
|
metanephros development
|
GO:0001656 |
16 |
0.026
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.026
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.026
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.026
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.026
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.026
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.026
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.026
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.025
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.025
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.025
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.025
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.025
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.025
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.024
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.024
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.024
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.024
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.024
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.024
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.024
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.024
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.024
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.024
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.023
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.023
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.023
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.023
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.023
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.023
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.023
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.023
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.022
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.022
|
Zebrafish |
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.022
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.022
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.022
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.022
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.022
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.022
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.022
|
|
|
|
memory
|
GO:0007613 |
3 |
0.022
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.022
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.022
|
Mouse Fly |
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.022
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.022
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.022
|
|
|
|
fertilization
|
GO:0009566 |
12 |
0.022
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.022
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.021
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.021
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.021
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.021
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.021
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.021
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.021
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.021
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.021
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.021
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.021
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.020
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.020
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.020
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.020
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.020
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.020
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.020
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.019
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.019
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.019
|
Fly |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.019
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.019
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.019
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.019
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.019
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.019
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.019
|
|
|
|
positive regulation of dna repair
|
GO:0045739 |
25 |
0.019
|
|
|
|
positive regulation of anoikis
|
GO:2000210 |
4 |
0.019
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.019
|
Human Zebrafish Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.018
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.018
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.018
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.018
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.018
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.018
|
Fly |
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.018
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.017
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.017
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.017
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.017
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.017
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.017
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.017
|
Mouse Fly |
|
|
axon development
|
GO:0061564 |
34 |
0.017
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.017
|
Worm Fly |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.017
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.017
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.017
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.017
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.017
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.017
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.017
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
17 |
0.017
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.017
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.016
|
Worm |
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.016
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.016
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.016
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.016
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.016
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.016
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.016
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.016
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.016
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.016
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.016
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.016
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.016
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.016
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.016
|
|
|
|
aging
|
GO:0007568 |
66 |
0.016
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.016
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.016
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.015
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.015
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.015
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.015
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.015
|
Fly |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.015
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.015
|
Mouse Fly |
|
|
microtubule nucleation
|
GO:0007020 |
6 |
0.015
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.015
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.015
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.015
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.015
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.015
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.015
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.015
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.015
|
Mouse Fly |
|
|
reproductive process
|
GO:0022414 |
106 |
0.015
|
Mouse Fly |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.015
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.015
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.015
|
|
|
|
glomerular parietal epithelial cell differentiation
|
GO:0072139 |
3 |
0.014
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.014
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.014
|
|
|
|
protein folding
|
GO:0006457 |
38 |
0.014
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.014
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.014
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.014
|
|
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.014
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.014
|
|
