Homo sapiens

184 known processes

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

(Aliases: Arc-1,CDHE,ECAD,LCAM,UVO,CD324)

CDH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
catagen GO:0042637 3 1.000
Human
cardiac muscle cell action potential involved in contraction GO:0086002 21 1.000
Human
keratinization GO:0031424 2 1.000
Human
cardiac muscle cell contraction GO:0086003 4 1.000
desmosome assembly GO:0002159 4 1.000
negative regulation of catagen GO:0051796 1 1.000
Human
positive regulation of keratinocyte proliferation GO:0010838 4 0.999
Human
keratinocyte differentiation GO:0030216 36 0.999
Human
wnt signaling pathway GO:0016055 156 0.999
Human Mouse
negative regulation of wnt signaling pathway GO:0030178 69 0.999
Mouse
cell communication involved in cardiac conduction GO:0086065 18 0.999
Human
regulation of cardiac muscle cell contraction GO:0086004 23 0.999
Human
action potential GO:0001508 34 0.999
Human
cardiac conduction GO:0061337 23 0.999
Human
bundle of his cell to purkinje myocyte communication GO:0086069 8 0.999
Human
rho protein signal transduction GO:0007266 26 0.998
Human
cardiac muscle cell action potential GO:0086001 23 0.998
Human
skin development GO:0043588 76 0.998
Human
canonical wnt signaling pathway GO:0060070 116 0.998
Human Mouse
single organismal cell cell adhesion GO:0016337 148 0.997
positive regulation of intracellular protein transport GO:0090316 76 0.997
cardiac muscle contraction GO:0060048 34 0.996
regulation of cardiac muscle contraction GO:0055117 33 0.996
Human
regulation of membrane potential GO:0042391 95 0.996
Human
blood circulation GO:0008015 113 0.995
Human
regulation of smooth muscle cell proliferation GO:0048660 28 0.995
Human
cell migration involved in gastrulation GO:0042074 1 0.994
Zebrafish
salivary gland morphogenesis GO:0007435 4 0.994
Mouse
actin filament based movement GO:0030048 17 0.994
epidermal cell differentiation GO:0009913 45 0.994
Human
biological adhesion GO:0022610 331 0.994
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.994
Human
tube morphogenesis GO:0035239 95 0.993
Zebrafish Mouse
single organism cell adhesion GO:0098602 179 0.992
regulation of striated muscle contraction GO:0006942 37 0.990
Human
somatic stem cell maintenance GO:0035019 4 0.989
regulation of keratinocyte proliferation GO:0010837 11 0.989
Human
circulatory system process GO:0003013 113 0.989
Human
canonical wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition GO:0044334 2 0.988
cell adhesion GO:0007155 325 0.986
epidermis development GO:0008544 59 0.984
Human
establishment of protein localization to membrane GO:0090150 121 0.980
regulation of canonical wnt signaling pathway GO:0060828 88 0.978
Mouse
regulation of heart rate by cardiac conduction GO:0086091 19 0.977
Human
tissue morphogenesis GO:0048729 96 0.977
Zebrafish Mouse
regulation of cellular component movement GO:0051270 334 0.976
Human Mouse
regulation of actin filament based movement GO:1903115 24 0.976
Human
cerebral cortex radially oriented cell migration GO:0021799 1 0.976
positive regulation of transport GO:0051050 336 0.976
ventricular cardiac muscle cell action potential GO:0086005 15 0.975
Human
regulation of heart rate GO:0002027 38 0.972
Human
epithelium development GO:0060429 227 0.972
Human Zebrafish Mouse
system process GO:0003008 349 0.971
Human Mouse
cell junction organization GO:0034330 79 0.971
keratinocyte proliferation GO:0043616 17 0.970
Human
plasma membrane organization GO:0007009 115 0.969
positive regulation of cell cycle process GO:0090068 106 0.968
endothelial cell migration GO:0043542 86 0.967
Human
hair cycle GO:0042633 28 0.966
Human
regulation of protein localization GO:0032880 296 0.965
positive regulation of cell motility GO:2000147 177 0.963
Human
adherens junction organization GO:0034332 36 0.962
muscle cell proliferation GO:0033002 35 0.960
Human
positive regulation of proteoglycan biosynthetic process GO:1902730 3 0.959
regulation of cell motility GO:2000145 299 0.957
Human Mouse
response to organonitrogen compound GO:0010243 156 0.955
vasculature development GO:0001944 181 0.955
Human
epithelial cell proliferation GO:0050673 128 0.954
Human Mouse
embryonic morphogenesis GO:0048598 85 0.952
Zebrafish
regulation of cell adhesion GO:0030155 166 0.950
negative regulation of cellular component movement GO:0051271 106 0.950
ameboidal type cell migration GO:0001667 135 0.948
Human Zebrafish
embryonic forelimb morphogenesis GO:0035115 4 0.948
regulation of cell cycle GO:0051726 393 0.946
protein localization to organelle GO:0033365 280 0.940
regulation of melanosome transport GO:1902908 1 0.936
Human
morphogenesis of an epithelium GO:0002009 60 0.936
Zebrafish Mouse
tissue migration GO:0090130 119 0.932
Human Zebrafish
epithelial tube morphogenesis GO:0060562 38 0.932
Zebrafish
negative regulation of epidermis development GO:0045683 5 0.930
Human
establishment of protein localization to plasma membrane GO:0090002 68 0.927
actin mediated cell contraction GO:0070252 12 0.927
cardiac cell fate specification GO:0060912 1 0.925
negative regulation of cell death GO:0060548 345 0.924
small gtpase mediated signal transduction GO:0007264 78 0.924
Human
regulation of intracellular transport GO:0032386 195 0.921
negative regulation of cell motility GO:2000146 104 0.920
mesendoderm development GO:0048382 1 0.919
Zebrafish
positive regulation of cell migration GO:0030335 172 0.917
Human
negative regulation of developmental process GO:0051093 247 0.916
Human
epithelial cell differentiation GO:0030855 141 0.916
Human Mouse
regulation of protein import into nucleus GO:0042306 78 0.911
regulation of wnt signaling pathway GO:0030111 123 0.911
Mouse
cellular response to endogenous stimulus GO:0071495 336 0.903
negative regulation of transforming growth factor beta2 production GO:0032912 2 0.903
Human
negative regulation of cell adhesion GO:0007162 64 0.903
epithelium migration GO:0090132 119 0.903
Human Zebrafish
cardiovascular system development GO:0072358 262 0.901
Human
protein localization to plasma membrane GO:0072659 93 0.901
negative regulation of cardioblast cell fate specification GO:0009997 1 0.900
positive regulation of protein transport GO:0051222 135 0.899
ras protein signal transduction GO:0007265 73 0.891
Human
organ morphogenesis GO:0009887 147 0.891
Mouse
muscle contraction GO:0006936 73 0.889
regulation of nucleocytoplasmic transport GO:0046822 98 0.886
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.881
regulation of hair follicle maturation GO:0048819 3 0.880
Human
neuroblast proliferation GO:0007405 4 0.871
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 1 0.870
hair follicle morphogenesis GO:0031069 2 0.870
protein import into nucleus GO:0006606 104 0.859
regulation of system process GO:0044057 101 0.853
Human
protein localization to membrane GO:0072657 160 0.852
regulation of actin filament based process GO:0032970 141 0.849
Human
positive regulation of cell cycle GO:0045787 140 0.846
regulation of cellular amine metabolic process GO:0033238 11 0.846
embryonic skeletal joint morphogenesis GO:0060272 2 0.845
circulatory system development GO:0072359 262 0.842
Human
embryonic epithelial tube formation GO:0001838 4 0.840
Zebrafish
smooth muscle cell proliferation GO:0048659 28 0.834
Human
regulation of transferase activity GO:0051338 355 0.833
blood vessel development GO:0001568 172 0.830
Human
endomembrane system organization GO:0010256 196 0.830
positive regulation of immune system process GO:0002684 283 0.826
negative regulation of cell differentiation GO:0045596 171 0.822
cellular response to alcohol GO:0097306 29 0.821
regulation of protein targeting GO:1903533 91 0.819
intermediate filament organization GO:0045109 10 0.816
single organism nuclear import GO:1902593 104 0.814
chemotaxis GO:0006935 157 0.813
Human
positive regulation of protein import into nucleus GO:0042307 46 0.811
striated muscle contraction GO:0006941 52 0.810
single organism cellular localization GO:1902580 332 0.809
negative regulation of multicellular organismal process GO:0051241 317 0.807
Human
homotypic cell cell adhesion GO:0034109 47 0.805
Human
cell junction assembly GO:0034329 67 0.802
Mouse
cardiac muscle tissue development GO:0048738 39 0.802
regulation of establishment of protein localization GO:0070201 242 0.801
positive regulation of smoothened signaling pathway GO:0045880 4 0.786
regulation of locomotion GO:0040012 329 0.781
Human Mouse
proteoglycan metabolic process GO:0006029 29 0.777
actin filament based process GO:0030029 224 0.776
taxis GO:0042330 157 0.776
Human
low density lipoprotein particle mediated signaling GO:0055096 1 0.773
Human
morphogenesis of a polarized epithelium GO:0001738 3 0.768
wound healing GO:0042060 115 0.767
cell cell junction organization GO:0045216 69 0.767
positive regulation of programmed cell death GO:0043068 249 0.767
response to alcohol GO:0097305 64 0.755
regulation of intracellular protein transport GO:0033157 123 0.754
regulation of cellular ketone metabolic process GO:0010565 50 0.754
cell activation GO:0001775 213 0.745
cellular response to nitrogen compound GO:1901699 144 0.744
response to indole 3 methanol GO:0071680 5 0.743
mesenchymal cell development GO:0014031 50 0.741
regulation of cell cell adhesion GO:0022407 57 0.740
peripheral nervous system development GO:0007422 2 0.740
negative regulation of apoptotic process GO:0043066 316 0.736
motor neuron axon guidance GO:0008045 2 0.734
negative regulation of cellular amine metabolic process GO:0033239 3 0.731
muscle system process GO:0003012 81 0.727
regulation of protein kinase activity GO:0045859 289 0.727
cardiac muscle tissue morphogenesis GO:0055008 18 0.726
regulation of organ formation GO:0003156 4 0.724
gastrulation GO:0007369 51 0.718
Zebrafish
regulation of cardioblast differentiation GO:0051890 4 0.715
response to organic cyclic compound GO:0014070 204 0.715
positive regulation of sulfur metabolic process GO:0051176 3 0.715
intracellular protein transport GO:0006886 270 0.713
angiogenesis GO:0001525 147 0.711
Human
neural tube formation GO:0001841 3 0.711
Zebrafish
regulation of epithelial cell proliferation GO:0050678 113 0.710
Human Mouse
glycoprotein biosynthetic process GO:0009101 91 0.709
positive regulation of cell death GO:0010942 263 0.707
negative regulation of cell fate specification GO:0009996 3 0.704
regulation of melanin biosynthetic process GO:0048021 1 0.698
Human
muscle structure development GO:0061061 98 0.696
intermediate filament based process GO:0045103 17 0.696
regulation of cell cycle process GO:0010564 266 0.693
cellular response to oxygen containing compound GO:1901701 276 0.688
cell development GO:0048468 328 0.687
Mouse Rat
positive regulation of phosphorylation GO:0042327 394 0.683
coagulation GO:0050817 78 0.676
mesodermal cell fate commitment GO:0001710 2 0.671
negative regulation of protein modification process GO:0031400 200 0.668
positive regulation of endothelial cell proliferation GO:0001938 37 0.667
Human
blood vessel morphogenesis GO:0048514 162 0.665
Human
cell fate determination GO:0001709 3 0.664
regulation of blood circulation GO:1903522 59 0.660
Human
generation of neurons GO:0048699 152 0.647
Zebrafish Mouse Rat
digestive system development GO:0055123 75 0.645
Zebrafish Mouse
cardiac chamber development GO:0003205 30 0.644
enzyme linked receptor protein signaling pathway GO:0007167 303 0.640
Human
nephron tubule epithelial cell differentiation GO:0072160 3 0.640
response to lipid GO:0033993 206 0.640
membrane organization GO:0061024 292 0.639
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.637
ectoderm development GO:0007398 3 0.631
Zebrafish
hair follicle maturation GO:0048820 3 0.628
Human
tissue homeostasis GO:0001894 63 0.626
Human
nephron tubule formation GO:0072079 1 0.625
endoderm development GO:0007492 33 0.623
Zebrafish
regulation of rho protein signal transduction GO:0035023 79 0.611
cell junction maintenance GO:0034331 4 0.610
Zebrafish
digestive tract morphogenesis GO:0048546 56 0.606
Zebrafish
desmosome organization GO:0002934 5 0.601
cellular component morphogenesis GO:0032989 314 0.601
Mouse
cellular amino acid metabolic process GO:0006520 116 0.597
regulation of heart induction GO:0090381 2 0.596
protein targeting GO:0006605 187 0.595
anatomical structure maturation GO:0071695 9 0.592
Human
vesicle mediated transport GO:0016192 371 0.591
Human
regulation of protein localization to cell surface GO:2000008 15 0.590
Mouse
nucleocytoplasmic transport GO:0006913 176 0.582
negative regulation of cellular protein metabolic process GO:0032269 353 0.581
metanephric nephron morphogenesis GO:0072273 7 0.580
rac protein signal transduction GO:0016601 12 0.578
Human
cell substrate adhesion GO:0031589 132 0.576
Human
heparan sulfate proteoglycan biosynthetic process GO:0015012 8 0.576
protein localization to cell surface GO:0034394 28 0.573
Mouse
positive regulation of heparan sulfate proteoglycan biosynthetic process GO:0010909 3 0.568
response to lithium ion GO:0010226 2 0.566
cell cell signaling GO:0007267 155 0.563
specification of organ identity GO:0010092 3 0.562
negative regulation of glial cell differentiation GO:0045686 1 0.561
positive regulation of cell adhesion GO:0045785 84 0.557
Human
intermediate filament bundle assembly GO:0045110 5 0.550
heart process GO:0003015 62 0.549
Human
cardiac ventricle morphogenesis GO:0003208 20 0.549
cellular amine metabolic process GO:0044106 41 0.543
regulation of body fluid levels GO:0050878 99 0.540
Mouse
positive regulation of apoptotic process GO:0043065 246 0.535
formation of primary germ layer GO:0001704 42 0.529
carbohydrate derivative biosynthetic process GO:1901137 207 0.529
regulation of myelination GO:0031641 1 0.525
organic hydroxy compound metabolic process GO:1901615 147 0.524
Human
negative regulation of cell proliferation GO:0008285 228 0.520
Human Mouse
pharynx development GO:0060465 1 0.517
regulation of protein localization to nucleus GO:1900180 85 0.515
cell morphogenesis GO:0000902 296 0.515
Mouse
mesenchymal cell differentiation GO:0048762 52 0.511
negative regulation of apoptotic signaling pathway GO:2001234 97 0.510
regulation of cell differentiation GO:0045595 393 0.509
Mouse
cell projection organization GO:0030030 252 0.508
Human Rat
nervous system development GO:0007399 293 0.506
Zebrafish Mouse Rat
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.504
negative regulation of programmed cell death GO:0043069 321 0.504
cell cell junction assembly GO:0007043 25 0.503
Mouse
oligodendrocyte differentiation GO:0048709 7 0.503
positive regulation of cellular component movement GO:0051272 181 0.501
Human
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.500
Mouse
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.491
regulation of neural precursor cell proliferation GO:2000177 4 0.487
regulation of cell division GO:0051302 116 0.484
protein import GO:0017038 130 0.483
cardiac muscle cell cardiac muscle cell adhesion GO:0086042 1 0.478
Human
positive regulation of rho gtpase activity GO:0032321 56 0.478
catenin import into nucleus GO:0035411 18 0.477
ventricular cardiac muscle tissue development GO:0003229 14 0.477
muscle tissue development GO:0060537 62 0.475
apoptotic signaling pathway GO:0097190 268 0.473
nuclear transport GO:0051169 179 0.472
positive regulation of cell proliferation GO:0008284 301 0.471
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.469
Human Zebrafish Mouse
organ induction GO:0001759 4 0.467
negative regulation of interleukin 5 production GO:0032714 3 0.466
secondary metabolite biosynthetic process GO:0044550 2 0.464
Human
organ formation GO:0048645 3 0.464
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.463
regulation of glycoprotein metabolic process GO:1903018 19 0.462
regulation of erbb signaling pathway GO:1901184 27 0.461
Human
regulation of vesicle mediated transport GO:0060627 130 0.450
Human
amine metabolic process GO:0009308 44 0.448
negative regulation of hair follicle development GO:0051799 1 0.447
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.445
extrinsic apoptotic signaling pathway GO:0097191 119 0.444
positive regulation of apoptotic signaling pathway GO:2001235 70 0.443
regulation of oxidoreductase activity GO:0051341 43 0.440
Human
protein localization to nucleus GO:0034504 136 0.439
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.437
cellular lipid metabolic process GO:0044255 303 0.436
epithelial cell migration GO:0010631 119 0.435
Human Zebrafish
negative regulation of locomotion GO:0040013 118 0.434
transmembrane transport GO:0055085 399 0.434
cellular response to organic cyclic compound GO:0071407 127 0.433
glycosyl compound catabolic process GO:1901658 413 0.429
positive regulation of cellular catabolic process GO:0031331 284 0.426
cell projection assembly GO:0030031 126 0.421
Human
lung associated mesenchyme development GO:0060484 1 0.421
positive regulation of locomotion GO:0040017 186 0.419
Human
mitotic cell cycle GO:0000278 326 0.409
regulation of ion transmembrane transport GO:0034765 132 0.408
positive regulation of protein phosphorylation GO:0001934 313 0.403
positive regulation of cytoplasmic transport GO:1903651 82 0.399
positive regulation of hydrolase activity GO:0051345 331 0.399
positive regulation of epithelial cell proliferation GO:0050679 65 0.398
Human
regulation of mapk cascade GO:0043408 262 0.392
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.391
cell chemotaxis GO:0060326 112 0.389
regulation of apoptotic signaling pathway GO:2001233 175 0.387
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.384
positive regulation of protein kinase activity GO:0045860 190 0.382
neuron differentiation GO:0030182 138 0.382
Rat
regulation of endothelial cell proliferation GO:0001936 56 0.382
Human
multicellular organismal signaling GO:0035637 34 0.374
Human
cellular ketone metabolic process GO:0042180 80 0.369
organophosphate catabolic process GO:0046434 430 0.368
regulation of cell migration GO:0030334 289 0.368
Human Mouse
positive regulation of nucleoside metabolic process GO:0045979 186 0.367
ribonucleoside triphosphate catabolic process GO:0009203 391 0.363
purine nucleoside catabolic process GO:0006152 398 0.361
centromeric sister chromatid cohesion GO:0070601 3 0.361
establishment of organelle localization GO:0051656 59 0.359
Human
renal vesicle development GO:0072087 4 0.357
anatomical structure homeostasis GO:0060249 100 0.353
Human
mitotic cell cycle process GO:1903047 286 0.353
single organism membrane organization GO:0044802 268 0.352
heart formation GO:0060914 2 0.344
response to nitrogen compound GO:1901698 184 0.344
cuticle development GO:0042335 1 0.341
establishment of protein localization to organelle GO:0072594 172 0.340
regulation of cell fate commitment GO:0010453 7 0.336
intermediate filament cytoskeleton organization GO:0045104 17 0.335
purine containing compound catabolic process GO:0072523 411 0.335
somitogenesis GO:0001756 2 0.334
activation of immune response GO:0002253 114 0.332
cell division GO:0051301 168 0.331
morphogenesis of embryonic epithelium GO:0016331 4 0.330
Zebrafish
heart development GO:0007507 95 0.328
regulation of actin cytoskeleton organization GO:0032956 116 0.328
ribonucleoside triphosphate metabolic process GO:0009199 412 0.325
mating GO:0007618 1 0.325
neuron migration GO:0001764 11 0.323
Zebrafish Mouse
muscle tissue morphogenesis GO:0060415 19 0.323
response to wounding GO:0009611 168 0.322
cellular response to organonitrogen compound GO:0071417 124 0.320
response to low density lipoprotein particle GO:0055098 4 0.318
Human
response to growth factor GO:0070848 205 0.318
hair cycle process GO:0022405 12 0.314
Human
regulation of rho gtpase activity GO:0032319 66 0.308
blood coagulation GO:0007596 76 0.308
neurogenesis GO:0022008 169 0.308
Zebrafish Mouse Rat
gland development GO:0048732 48 0.305
Mouse Rat
hindbrain development GO:0030902 3 0.304
regulation of neuroblast proliferation GO:1902692 3 0.301
lipid metabolic process GO:0006629 381 0.301
proteoglycan biosynthetic process GO:0030166 20 0.300
striated muscle tissue development GO:0014706 59 0.296
protein oligomerization GO:0051259 173 0.296
Mouse
cellular response to metal ion GO:0071248 43 0.295
neurological system process GO:0050877 163 0.295
Mouse
locomotory behavior GO:0007626 1 0.294
gastrulation with mouth forming second GO:0001702 1 0.294
Zebrafish
endodermal cell fate commitment GO:0001711 4 0.293
negative regulation of transferase activity GO:0051348 124 0.292
regeneration GO:0031099 4 0.292
positive regulation of mapk cascade GO:0043410 190 0.291
negative regulation of phosphate metabolic process GO:0045936 267 0.289
organic hydroxy compound biosynthetic process GO:1901617 71 0.287
Human
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.287
regulation of cardioblast cell fate specification GO:0042686 1 0.286
cell morphogenesis involved in differentiation GO:0000904 144 0.285
Mouse
embryo development GO:0009790 123 0.281
Zebrafish Mouse
positive regulation of cell substrate adhesion GO:0010811 37 0.281
Human
positive regulation of cell division GO:0051781 59 0.277
positive regulation of developmental process GO:0051094 314 0.274
positive regulation of intracellular transport GO:0032388 104 0.274
heart morphogenesis GO:0003007 48 0.271
regulation of purine nucleotide metabolic process GO:1900542 264 0.270
smoothened signaling pathway GO:0007224 14 0.270
positive regulation of protein localization to nucleus GO:1900182 48 0.269
positive regulation of transcription factor import into nucleus GO:0042993 25 0.267
cell matrix adhesion GO:0007160 85 0.264
Human
organic anion transport GO:0015711 103 0.263
regulation of cell growth GO:0001558 135 0.258
cell fate commitment involved in formation of primary germ layer GO:0060795 6 0.255
regulation of neurogenesis GO:0050767 82 0.254
Mouse
lipoprotein particle mediated signaling GO:0055095 1 0.252
Human
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.252
defense response GO:0006952 315 0.251
protein kinase b signaling GO:0043491 69 0.247
negative regulation of cell fate commitment GO:0010454 3 0.244
regulation of monophenol monooxygenase activity GO:0032771 1 0.244
Human
establishment or maintenance of cell polarity GO:0007163 31 0.243
Zebrafish
cellular homeostasis GO:0019725 196 0.242
glycoprotein metabolic process GO:0009100 110 0.240
protein ubiquitination GO:0016567 314 0.239
morphogenesis of a branching epithelium GO:0061138 20 0.237
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.236
positive regulation of gtpase activity GO:0043547 166 0.236
positive chemotaxis GO:0050918 33 0.235
Human
positive regulation of gtp catabolic process GO:0033126 166 0.234
positive regulation of cellular amine metabolic process GO:0033240 7 0.234
cell projection morphogenesis GO:0048858 129 0.233
regulation of transmembrane transport GO:0034762 139 0.231
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.231
stem cell differentiation GO:0048863 93 0.231
purine ribonucleoside catabolic process GO:0046130 398 0.230
branching morphogenesis of an epithelial tube GO:0048754 19 0.229
regulation of heparan sulfate proteoglycan biosynthetic process GO:0010908 3 0.227
maintenance of organ identity GO:0048496 5 0.227
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.227
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.226
positive regulation of melanin biosynthetic process GO:0048023 1 0.226
Human
positive regulation of response to external stimulus GO:0032103 88 0.226
Human
regulation of cytoskeleton organization GO:0051493 177 0.224
pigmentation GO:0043473 22 0.224
Human
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.223
Human
positive regulation of map kinase activity GO:0043406 80 0.223
pigment biosynthetic process GO:0046148 10 0.222
Human
negative regulation of cell cycle GO:0045786 193 0.220
negative regulation of protein metabolic process GO:0051248 391 0.220
regulation of protein transport GO:0051223 213 0.220
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.218
regulation of heart contraction GO:0008016 50 0.217
Human
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.217
Human
response to oxygen containing compound GO:1901700 369 0.217
regulation of nucleotide catabolic process GO:0030811 205 0.216
digestive tract development GO:0048565 75 0.216
Zebrafish Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.213
microtubule cytoskeleton organization GO:0000226 176 0.213
neuron development GO:0048666 113 0.213
Rat
ubiquitin dependent protein catabolic process GO:0006511 206 0.212
positive regulation of cellular component organization GO:0051130 376 0.208
immune response GO:0006955 307 0.207
ion homeostasis GO:0050801 230 0.207
regulation of cell development GO:0060284 161 0.206
Mouse
central nervous system development GO:0007417 123 0.206
Rat
regulation of behavior GO:0050795 82 0.205
Human
signal transduction in absence of ligand GO:0038034 22 0.205
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.203
melanin metabolic process GO:0006582 1 0.203
Human
epidermis morphogenesis GO:0048730 3 0.202
cell cycle arrest GO:0007050 71 0.201
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.199
cerebral cortex cell migration GO:0021795 3 0.199
ribonucleoside catabolic process GO:0042454 406 0.199
positive regulation of protein kinase b signaling GO:0051897 42 0.197
negative regulation of phosphorus metabolic process GO:0010563 267 0.194
guanosine containing compound metabolic process GO:1901068 244 0.193
positive regulation of transferase activity GO:0051347 227 0.193
positive regulation of oxidoreductase activity GO:0051353 26 0.190
Human
tube development GO:0035295 125 0.190
Zebrafish Mouse
immune response activating signal transduction GO:0002757 90 0.189
protein localization to adherens junction GO:0071896 2 0.189
positive regulation of melanosome transport GO:1902910 1 0.189
Human
response to steroid hormone GO:0048545 80 0.188
cell cell adhesion GO:0098609 19 0.187
Human Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.187
response to hormone GO:0009725 175 0.186
divalent inorganic cation transport GO:0072511 158 0.185
positive regulation of catabolic process GO:0009896 310 0.184
sprouting angiogenesis GO:0002040 29 0.184
Human
protein maturation GO:0051604 233 0.182
chromatin organization GO:0006325 351 0.181
negative regulation of protein sumoylation GO:0033234 5 0.181
innate immune response GO:0045087 178 0.181
myeloid leukocyte migration GO:0097529 62 0.180
forebrain generation of neurons GO:0021872 3 0.180
hair follicle development GO:0001942 11 0.180
Human
regulation of cell morphogenesis GO:0022604 153 0.180
regulation of map kinase activity GO:0043405 108 0.180
mesenchyme development GO:0060485 59 0.179
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 2 0.178
sulfur compound biosynthetic process GO:0044272 38 0.177
brain development GO:0007420 97 0.176
Rat
cytoplasmic transport GO:0016482 379 0.176
purine nucleoside triphosphate catabolic process GO:0009146 392 0.176
epiboly involved in gastrulation with mouth forming second GO:0055113 1 0.175
Zebrafish
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.175
Human Mouse
neuroendocrine cell differentiation GO:0061101 2 0.174
cellular chemical homeostasis GO:0055082 180 0.173
nucleotide catabolic process GO:0009166 408 0.172
response to cytokine GO:0034097 232 0.171
regulation of protein serine threonine kinase activity GO:0071900 179 0.171
memory GO:0007613 3 0.170
regulation of sulfur metabolic process GO:0042762 5 0.170
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.170
negative regulation of apoptotic process in bone marrow GO:0071866 1 0.167
thymus development GO:0048538 3 0.166
positive regulation of protein export from nucleus GO:0046827 6 0.166
posttranscriptional regulation of gene expression GO:0010608 213 0.166
Human
positive regulation of myeloid cell differentiation GO:0045639 39 0.165
activation of protein kinase activity GO:0032147 90 0.164
negative regulation of axonogenesis GO:0050771 4 0.163

CDH1 disease predictions

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 104 0.973
Human
muscular disease DOID:0080000 114 0.973
Human
heart disease DOID:114 68 0.973
Human
cardiomyopathy DOID:0050700 50 0.973
Human
intrinsic cardiomyopathy DOID:0060036 50 0.973
Human
cardiovascular system disease DOID:1287 106 0.973
Human
musculoskeletal system disease DOID:17 223 0.973
Human
muscle tissue disease DOID:66 113 0.973
Human
disease of cellular proliferation DOID:14566 174 0.547
cancer DOID:162 167 0.308
organ system cancer DOID:0050686 164 0.308
gastrointestinal system cancer DOID:3119 52 0.290
integumentary system disease DOID:16 43 0.194
Human