Homo sapiens

136 known processes

CDK7

cyclin-dependent kinase 7

(Aliases: CDKN7,MO15,CAK1,p39MO15,STK1)

CDK7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 1.000
Yeast
purine nucleoside monophosphate catabolic process GO:0009128 158 0.995
nucleotide excision repair GO:0006289 31 0.992
ribonucleoside monophosphate catabolic process GO:0009158 158 0.987
nucleoside catabolic process GO:0009164 408 0.977
nucleoside triphosphate catabolic process GO:0009143 394 0.976
organophosphate catabolic process GO:0046434 430 0.973
nucleoside phosphate catabolic process GO:1901292 412 0.971
purine containing compound catabolic process GO:0072523 411 0.968
ribonucleoside triphosphate catabolic process GO:0009203 391 0.966
atp metabolic process GO:0046034 176 0.966
nucleoside monophosphate catabolic process GO:0009125 159 0.963
purine nucleoside catabolic process GO:0006152 398 0.955
ribonucleotide catabolic process GO:0009261 405 0.953
purine ribonucleotide catabolic process GO:0009154 404 0.952
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.951
purine nucleoside triphosphate metabolic process GO:0009144 412 0.949
ribonucleoside catabolic process GO:0042454 406 0.944
nucleotide catabolic process GO:0009166 408 0.942
purine nucleotide catabolic process GO:0006195 405 0.939
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.938
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.937
ribonucleoside triphosphate metabolic process GO:0009199 412 0.930
nucleoside triphosphate metabolic process GO:0009141 422 0.910
purine nucleoside triphosphate catabolic process GO:0009146 392 0.905
ribonucleoside monophosphate metabolic process GO:0009161 187 0.845
atp catabolic process GO:0006200 157 0.836
nucleoside monophosphate metabolic process GO:0009123 191 0.823
purine ribonucleoside metabolic process GO:0046128 437 0.809
purine ribonucleoside catabolic process GO:0046130 398 0.804
glycosyl compound catabolic process GO:1901658 413 0.774
purine nucleoside monophosphate metabolic process GO:0009126 186 0.747
post embryonic development GO:0009791 2 0.624
nucleotide excision repair dna incision GO:0033683 7 0.597
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.570
dna repair GO:0006281 198 0.530
regulation of cell cycle GO:0051726 393 0.519
Rat Fly
cellular response to dna damage stimulus GO:0006974 379 0.310
mitotic cell cycle process GO:1903047 286 0.262
Fly
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.248
adult heart development GO:0007512 6 0.243
mrna splicing via spliceosome GO:0000398 89 0.218
epithelium development GO:0060429 227 0.207
endocytosis GO:0006897 159 0.203
ras protein signal transduction GO:0007265 73 0.193
oogenesis GO:0048477 2 0.160
vesicle mediated transport GO:0016192 371 0.153
regulation of mitotic cell cycle phase transition GO:1901990 118 0.143
embryo development GO:0009790 123 0.142
Worm
positive regulation of cell death GO:0010942 263 0.134
response to abiotic stimulus GO:0009628 336 0.132
regulation of mrna processing GO:0050684 48 0.124
positive regulation of catabolic process GO:0009896 310 0.101
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.099
rna splicing GO:0008380 131 0.099
negative regulation of programmed cell death GO:0043069 321 0.095
mrna metabolic process GO:0016071 175 0.093
Yeast
positive regulation of apoptotic process GO:0043065 246 0.093
regulation of protein kinase activity GO:0045859 289 0.085
Fly
cellular amine metabolic process GO:0044106 41 0.084
histone acetylation GO:0016573 93 0.081
negative regulation of cell cycle process GO:0010948 121 0.080
small gtpase mediated signal transduction GO:0007264 78 0.079
gtp metabolic process GO:0046039 239 0.079
sex differentiation GO:0007548 45 0.077
macromolecular complex remodeling GO:0034367 16 0.076
female gamete generation GO:0007292 2 0.072
guanosine containing compound metabolic process GO:1901068 244 0.070
mitotic cell cycle GO:0000278 326 0.070
Worm Fly
response to decreased oxygen levels GO:0036293 96 0.069
reproductive process GO:0022414 106 0.068
establishment of protein localization to mitochondrion GO:0072655 22 0.067
covalent chromatin modification GO:0016569 254 0.064
dna conformation change GO:0071103 113 0.064
single organism reproductive process GO:0044702 98 0.063
cardiovascular system development GO:0072358 262 0.062
regulation of protein serine threonine kinase activity GO:0071900 179 0.060
Fly
negative regulation of histone modification GO:0031057 19 0.060
regulation of mitotic cell cycle GO:0007346 189 0.060
single organism cellular localization GO:1902580 332 0.055
microtubule based process GO:0007017 210 0.054
ncrna metabolic process GO:0034660 108 0.053
receptor mediated endocytosis GO:0006898 84 0.052
regulation of dna metabolic process GO:0051052 153 0.052
epithelial cell differentiation GO:0030855 141 0.051
nervous system development GO:0007399 293 0.051
nitrogen compound transport GO:0071705 191 0.050
positive regulation of phosphorylation GO:0042327 394 0.050
internal peptidyl lysine acetylation GO:0018393 97 0.048
g protein coupled receptor signaling pathway GO:0007186 207 0.048
hair cell differentiation GO:0035315 2 0.047
negative regulation of cellular amine metabolic process GO:0033239 3 0.047
embryo development ending in birth or egg hatching GO:0009792 34 0.046
Worm
head development GO:0060322 108 0.046
amine metabolic process GO:0009308 44 0.043
negative regulation of organelle organization GO:0010639 126 0.042
single organism membrane organization GO:0044802 268 0.042
ventricular system development GO:0021591 1 0.041
positive regulation of organelle organization GO:0010638 195 0.040
negative regulation of protein metabolic process GO:0051248 391 0.039
regulation of nucleotide catabolic process GO:0030811 205 0.039
negative regulation of apoptotic process GO:0043066 316 0.038
prenylation GO:0097354 6 0.038
guanosine containing compound catabolic process GO:1901069 239 0.038
circulatory system development GO:0072359 262 0.037
mrna processing GO:0006397 133 0.037
Yeast
cellular protein complex assembly GO:0043623 188 0.036
positive regulation of nucleotide metabolic process GO:0045981 230 0.036
positive regulation of programmed cell death GO:0043068 249 0.036
chromatin organization GO:0006325 351 0.036
regulation of kinase activity GO:0043549 314 0.036
Fly
immune response GO:0006955 307 0.035
spindle assembly GO:0051225 29 0.035
regulation of meiotic cell cycle GO:0051445 4 0.035
mapk cascade GO:0000165 288 0.033
regulation of mapk cascade GO:0043408 262 0.033
positive regulation of cellular component organization GO:0051130 376 0.032
negative regulation of chromosome organization GO:2001251 48 0.032
rab protein signal transduction GO:0032482 4 0.032
regulation of ras protein signal transduction GO:0046578 155 0.031
negative regulation of phosphate metabolic process GO:0045936 267 0.031
reproductive system development GO:0061458 56 0.031
regulation of transferase activity GO:0051338 355 0.031
Fly
positive regulation of hydrolase activity GO:0051345 331 0.031
mitochondrion organization GO:0007005 156 0.031
brain development GO:0007420 97 0.030
cellular amino acid metabolic process GO:0006520 116 0.030
regulation of cellular component biogenesis GO:0044087 281 0.030
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.030
gtp catabolic process GO:0006184 237 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.029
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.029
cellular macromolecule catabolic process GO:0044265 380 0.028
cytoplasmic transport GO:0016482 379 0.028
transmembrane transport GO:0055085 399 0.028
microtubule cytoskeleton organization GO:0000226 176 0.028
dna integrity checkpoint GO:0031570 71 0.028
nucleic acid transport GO:0050657 39 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.028
meiotic chromosome segregation GO:0045132 4 0.028
protein targeting GO:0006605 187 0.028
defense response GO:0006952 315 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.027
peptidyl lysine modification GO:0018205 144 0.027
intracellular protein transport GO:0006886 270 0.027
dna damage checkpoint GO:0000077 68 0.027
regulation of cell cycle phase transition GO:1901987 126 0.027
regulation of protein localization GO:0032880 296 0.027
lipid metabolic process GO:0006629 381 0.026
establishment of protein localization to organelle GO:0072594 172 0.026
meiosis i GO:0007127 4 0.025
gonad development GO:0008406 34 0.025
multicellular organismal aging GO:0010259 3 0.025
negative regulation of cell death GO:0060548 345 0.024
signal transduction by phosphorylation GO:0023014 297 0.024
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.024
response to cytokine GO:0034097 232 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
locomotory behavior GO:0007626 1 0.023
nuclear export GO:0051168 69 0.023
tissue regeneration GO:0042246 3 0.023
organophosphate biosynthetic process GO:0090407 163 0.023
negative regulation of histone acetylation GO:0035067 6 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
membrane organization GO:0061024 292 0.022
alcohol metabolic process GO:0006066 114 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
nucleobase containing compound transport GO:0015931 51 0.022
rna processing GO:0006396 255 0.022
Yeast
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
response to oxygen levels GO:0070482 100 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
negative regulation of cell cycle GO:0045786 193 0.021
transposition rna mediated GO:0032197 0 0.021
innate immune response GO:0045087 178 0.021
rna transport GO:0050658 39 0.021
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
response to other organism GO:0051707 261 0.021
anterior posterior axis specification GO:0009948 2 0.021
developmental process involved in reproduction GO:0003006 66 0.020
positive regulation of nucleotide catabolic process GO:0030813 185 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.020
multicellular organismal reproductive process GO:0048609 40 0.020
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
proteasomal protein catabolic process GO:0010498 176 0.020
mrna export from nucleus GO:0006406 29 0.020
cell division GO:0051301 168 0.019
establishment of protein localization to membrane GO:0090150 121 0.019
cell development GO:0048468 328 0.019
reproduction GO:0000003 63 0.018
reproductive structure development GO:0048608 55 0.018
neuroblast proliferation GO:0007405 4 0.018
protein catabolic process GO:0030163 325 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
organelle assembly GO:0070925 176 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
dna templated transcription initiation GO:0006352 35 0.018
maintenance of location GO:0051235 112 0.018
central nervous system development GO:0007417 123 0.018
cell fate determination GO:0001709 3 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
alternative mrna splicing via spliceosome GO:0000380 27 0.017
cation transmembrane transport GO:0098655 238 0.017
chromatin modification GO:0016568 298 0.017
epidermis development GO:0008544 59 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
protein processing GO:0016485 226 0.016
generation of neurons GO:0048699 152 0.016
regulation of rna splicing GO:0043484 62 0.016
protein localization to organelle GO:0033365 280 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
development of primary sexual characteristics GO:0045137 35 0.016
regulation of proteolysis GO:0030162 293 0.016
response to wounding GO:0009611 168 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
rho protein signal transduction GO:0007266 26 0.016
mitotic cell cycle phase transition GO:0044772 162 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
stem cell division GO:0017145 2 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
skin development GO:0043588 76 0.015
positive regulation of protein complex assembly GO:0031334 86 0.015
regulation of ras gtpase activity GO:0032318 128 0.015
dna recombination GO:0006310 77 0.015
mitotic cell cycle checkpoint GO:0007093 68 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
regulation of ion transport GO:0043269 189 0.014
regulation of secretion GO:0051046 194 0.014
negative regulation of kinase activity GO:0033673 106 0.014
regulation of cell differentiation GO:0045595 393 0.014
neurogenesis GO:0022008 169 0.014
response to hypoxia GO:0001666 96 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
regulation of cellular response to stress GO:0080135 244 0.014
protein folding GO:0006457 38 0.014
blastocyst development GO:0001824 3 0.014
cellular lipid metabolic process GO:0044255 303 0.014
positive regulation of developmental process GO:0051094 314 0.014
segmentation GO:0035282 4 0.014
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.014
peptidyl serine modification GO:0018209 106 0.014
spermatid differentiation GO:0048515 4 0.013
regulation of metal ion transport GO:0010959 120 0.013
negative regulation of protein processing GO:0010955 142 0.013
positive regulation of transferase activity GO:0051347 227 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
regulation of mrna splicing via spliceosome GO:0048024 32 0.013
positive regulation of dna metabolic process GO:0051054 73 0.013
protein localization to membrane GO:0072657 160 0.013
apoptotic signaling pathway GO:0097190 268 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
neuron differentiation GO:0030182 138 0.013
determination of adult lifespan GO:0008340 2 0.013
mitochondrial transport GO:0006839 60 0.013
heart development GO:0007507 95 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
fatty acid metabolic process GO:0006631 115 0.013
multi organism reproductive process GO:0044703 54 0.013
regulation of chromatin modification GO:1903308 51 0.013
spermatid development GO:0007286 4 0.013
actin filament based process GO:0030029 224 0.013
cell cycle phase transition GO:0044770 173 0.013
cellular protein catabolic process GO:0044257 261 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
negative regulation of proteolysis GO:0045861 132 0.012
cell growth GO:0016049 160 0.012
regulation of cell cycle process GO:0010564 266 0.012
negative regulation of protein modification process GO:0031400 200 0.012
response to radiation GO:0009314 151 0.012
positive regulation of cell cycle GO:0045787 140 0.012
centrosome organization GO:0051297 58 0.012
regulation of cellular component movement GO:0051270 334 0.012
regulation of binding GO:0051098 111 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
negative regulation of protein maturation GO:1903318 142 0.012
transposition GO:0032196 8 0.012
regulation of cell division GO:0051302 116 0.012
response to nitrogen compound GO:1901698 184 0.012
metal ion transport GO:0030001 272 0.012
associative learning GO:0008306 1 0.012
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.012
response to external biotic stimulus GO:0043207 261 0.012
oocyte development GO:0048599 1 0.012
oocyte differentiation GO:0009994 2 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
double strand break repair GO:0006302 101 0.011
sexual reproduction GO:0019953 37 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.011
positive regulation of dna repair GO:0045739 25 0.011
regeneration GO:0031099 4 0.011
peptidyl serine phosphorylation GO:0018105 101 0.011
response to calcium ion GO:0051592 46 0.011
nuclear transport GO:0051169 179 0.011
spindle organization GO:0007051 53 0.011
endomembrane system organization GO:0010256 196 0.011
protein localization to mitochondrion GO:0070585 25 0.011
hindbrain development GO:0030902 3 0.011
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.011
nuclear division GO:0000280 128 0.011
Fly
positive regulation of chromosome organization GO:2001252 41 0.011
response to oxidative stress GO:0006979 121 0.011
negative adaptation of signaling pathway GO:0022401 7 0.011
regulation of gtpase activity GO:0043087 180 0.011
regulation of cytokine production GO:0001817 232 0.010
body morphogenesis GO:0010171 11 0.010
7 methylguanosine mrna capping GO:0006370 7 0.010
Yeast
regulation of growth GO:0040008 165 0.010
regulation of chromatin organization GO:1902275 56 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010
spindle elongation GO:0051231 4 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
midgut development GO:0007494 1 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
protein dna complex assembly GO:0065004 64 0.010
ncrna processing GO:0034470 83 0.010
response to biotic stimulus GO:0009607 276 0.010
cilium organization GO:0044782 68 0.010
tripartite regional subdivision GO:0007351 2 0.010

CDK7 disease predictions

Disease DO term ID Size Probability Func Analog Org
xeroderma pigmentosum DOID:0050427 8 0.084
sensory system disease DOID:0050155 203 0.011
eye and adnexa disease DOID:1492 150 0.011
nervous system disease DOID:863 431 0.011
eye disease DOID:5614 149 0.011
central nervous system disease DOID:331 186 0.010
neurodegenerative disease DOID:1289 102 0.010