Homo sapiens

0 known processes

CDK8

cyclin-dependent kinase 8

(Aliases: K35,MGC126074,MGC126075)

CDK8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
snrna metabolic process GO:0016073 15 0.997
Fly
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.984
androgen biosynthetic process GO:0006702 3 0.969
regulation of cell cycle GO:0051726 393 0.953
Yeast Fly
regulation of cell cycle phase transition GO:1901987 126 0.948
Fly
post embryonic development GO:0009791 2 0.938
Worm Fly
regulation of cell cycle process GO:0010564 266 0.928
Fly
dna integrity checkpoint GO:0031570 71 0.925
Fly
regulation of cell differentiation GO:0045595 393 0.907
negative regulation of cell cycle phase transition GO:1901988 89 0.901
Fly
mitotic cell cycle phase transition GO:0044772 162 0.865
Fly
dna damage checkpoint GO:0000077 68 0.864
Fly
mitotic dna damage checkpoint GO:0044773 28 0.816
Fly
regulation of mitotic cell cycle GO:0007346 189 0.775
Fly
ncrna processing GO:0034470 83 0.773
Fly
cell cycle phase transition GO:0044770 173 0.753
Fly
negative regulation of cell cycle GO:0045786 193 0.672
Fly
negative regulation of cell differentiation GO:0045596 171 0.672
regulation of mitotic cell cycle phase transition GO:1901990 118 0.647
Fly
negative regulation of cell proliferation GO:0008285 228 0.646
stem cell maintenance GO:0019827 19 0.637
dna templated transcription initiation GO:0006352 35 0.602
intracellular receptor signaling pathway GO:0030522 104 0.598
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.594
positive regulation of interferon gamma mediated signaling pathway GO:0060335 2 0.528
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.521
Fly
mitotic cell cycle GO:0000278 326 0.507
Fly
nervous system development GO:0007399 293 0.484
Fly
negative regulation of mitotic cell cycle GO:0045930 102 0.447
Fly
negative regulation of cell cycle process GO:0010948 121 0.416
Fly
negative regulation of cell development GO:0010721 48 0.411
androgen receptor signaling pathway GO:0030521 34 0.388
negative regulation of developmental process GO:0051093 247 0.388
Worm
vitamin d receptor signaling pathway GO:0070561 4 0.357
rna 3 end processing GO:0031123 35 0.356
Fly
mitotic cell cycle process GO:1903047 286 0.352
Fly
mitotic cell cycle checkpoint GO:0007093 68 0.350
Fly
negative regulation of multicellular organismal process GO:0051241 317 0.346
Worm
regulation of cell development GO:0060284 161 0.321
neuroblast proliferation GO:0007405 4 0.314
generation of neurons GO:0048699 152 0.301
Fly
cell cycle checkpoint GO:0000075 117 0.290
Fly
mitotic g2 dna damage checkpoint GO:0007095 7 0.286
Fly
innate immune response GO:0045087 178 0.282
ncrna metabolic process GO:0034660 108 0.281
Fly
cell development GO:0048468 328 0.263
Fly
lipid metabolic process GO:0006629 381 0.258
tube morphogenesis GO:0035239 95 0.257
g2 dna damage checkpoint GO:0031572 26 0.257
Fly
neuron differentiation GO:0030182 138 0.255
Fly
mitotic dna integrity checkpoint GO:0044774 30 0.254
Fly
cellular component morphogenesis GO:0032989 314 0.229
Fly
cellular response to thyroid hormone stimulus GO:0097067 9 0.226
positive regulation of transport GO:0051050 336 0.214
cellular response to dna damage stimulus GO:0006974 379 0.213
Fly
embryonic hemopoiesis GO:0035162 4 0.209
positive regulation of cell proliferation GO:0008284 301 0.203
regulation of neuroblast proliferation GO:1902692 3 0.195
neuron projection development GO:0031175 106 0.194
Fly
circulatory system development GO:0072359 262 0.184
anatomical structure formation involved in morphogenesis GO:0048646 284 0.180
regulation of neural precursor cell proliferation GO:2000177 4 0.178
oogenesis GO:0048477 2 0.175
response to external biotic stimulus GO:0043207 261 0.171
cellular protein complex assembly GO:0043623 188 0.166
defense response GO:0006952 315 0.165
cell projection organization GO:0030030 252 0.155
Fly
signal transduction by phosphorylation GO:0023014 297 0.149
organ morphogenesis GO:0009887 147 0.146
Fly
ncrna 3 end processing GO:0043628 4 0.146
Fly
snrna processing GO:0016180 14 0.144
Fly
lipid biosynthetic process GO:0008610 177 0.138
immune response GO:0006955 307 0.137
female gamete generation GO:0007292 2 0.136
regulation of neurogenesis GO:0050767 82 0.131
neurogenesis GO:0022008 169 0.130
Fly
regulation of establishment of protein localization GO:0070201 242 0.130
positive regulation of protein localization to nucleus GO:1900182 48 0.124
regulation of anatomical structure morphogenesis GO:0022603 286 0.121
positive regulation of protein import into nucleus GO:0042307 46 0.119
neuron development GO:0048666 113 0.119
Fly
regulation of nervous system development GO:0051960 88 0.117
response to biotic stimulus GO:0009607 276 0.115
mapk cascade GO:0000165 288 0.114
cytoplasmic transport GO:0016482 379 0.113
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.112
Yeast
cell projection morphogenesis GO:0048858 129 0.108
Fly
stem cell differentiation GO:0048863 93 0.107
negative regulation of neural precursor cell proliferation GO:2000178 1 0.101
regulation of vitamin d receptor signaling pathway GO:0070562 3 0.100
neuron projection morphogenesis GO:0048812 50 0.097
Fly
response to other organism GO:0051707 261 0.096
cellular response to growth factor stimulus GO:0071363 197 0.096
positive regulation of immune system process GO:0002684 283 0.093
vasculature development GO:0001944 181 0.092
response to growth factor GO:0070848 205 0.092
cellular response to endogenous stimulus GO:0071495 336 0.091
photoreceptor cell differentiation GO:0046530 2 0.091
cellular component assembly involved in morphogenesis GO:0010927 73 0.088
positive regulation of protein transport GO:0051222 135 0.088
regulation of mapk cascade GO:0043408 262 0.086
blastocyst development GO:0001824 3 0.086
cellular macromolecule catabolic process GO:0044265 380 0.085
Yeast
response to extracellular stimulus GO:0009991 85 0.082
Yeast
mitotic g2 m transition checkpoint GO:0044818 9 0.080
Fly
protein localization to organelle GO:0033365 280 0.078
secretion GO:0046903 254 0.076
negative regulation of nervous system development GO:0051961 28 0.075
embryo development GO:0009790 123 0.074
Worm
cell division GO:0051301 168 0.074
multicellular organismal reproductive process GO:0048609 40 0.073
defense response to bacterium GO:0042742 63 0.071
embryo development ending in birth or egg hatching GO:0009792 34 0.071
Worm
thyroid hormone generation GO:0006590 2 0.070
cardiovascular system development GO:0072358 262 0.069
reproductive process GO:0022414 106 0.069
regulation of protein targeting GO:1903533 91 0.069
cellular response to external stimulus GO:0071496 111 0.069
Yeast
multicellular organismal aging GO:0010259 3 0.068
negative regulation of programmed cell death GO:0043069 321 0.068
stem cell development GO:0048864 69 0.066
cell morphogenesis GO:0000902 296 0.065
Fly
regulation of growth rate GO:0040009 1 0.065
positive regulation of developmental process GO:0051094 314 0.064
response to abiotic stimulus GO:0009628 336 0.064
epithelium development GO:0060429 227 0.064
positive regulation of cytoplasmic transport GO:1903651 82 0.062
single organism reproductive process GO:0044702 98 0.062
nucleoside triphosphate metabolic process GO:0009141 422 0.061
regulation of protein localization GO:0032880 296 0.061
positive regulation of intracellular transport GO:0032388 104 0.060
regulation of transferase activity GO:0051338 355 0.060
regulation of response to external stimulus GO:0032101 222 0.060
defense response to other organism GO:0098542 129 0.060
regulation of growth GO:0040008 165 0.059
Yeast
regulation of defense response GO:0031347 154 0.059
response to oxygen containing compound GO:1901700 369 0.058
positive regulation of cell differentiation GO:0045597 211 0.057
cellular lipid metabolic process GO:0044255 303 0.056
cellular amino acid metabolic process GO:0006520 116 0.056
single organism cellular localization GO:1902580 332 0.056
primary neural tube formation GO:0014020 3 0.054
regulation of cellular amine metabolic process GO:0033238 11 0.054
dna repair GO:0006281 198 0.054
muscle structure development GO:0061061 98 0.054
negative regulation of neurogenesis GO:0050768 26 0.054
eye development GO:0001654 42 0.053
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.053
axon development GO:0061564 34 0.052
Fly
regulation of cytoskeleton organization GO:0051493 177 0.052
potassium ion transport GO:0006813 62 0.051
developmental process involved in reproduction GO:0003006 66 0.049
blood vessel development GO:0001568 172 0.049
gland development GO:0048732 48 0.049
meiosis i GO:0007127 4 0.049
microtubule based process GO:0007017 210 0.048
cell type specific apoptotic process GO:0097285 125 0.047
growth GO:0040007 202 0.047
Yeast
negative regulation of apoptotic process GO:0043066 316 0.046
regulation of immune response GO:0050776 201 0.046
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.044
cellular response to organic cyclic compound GO:0071407 127 0.043
neural tube formation GO:0001841 3 0.043
enzyme linked receptor protein signaling pathway GO:0007167 303 0.043
regulation of protein kinase activity GO:0045859 289 0.042
actin filament based process GO:0030029 224 0.042
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.042
regulation of stem cell proliferation GO:0072091 15 0.042
negative regulation of cellular component organization GO:0051129 235 0.041
developmental growth involved in morphogenesis GO:0060560 23 0.041
morphogenesis of embryonic epithelium GO:0016331 4 0.040
cellular response to nutrient levels GO:0031669 69 0.038
Yeast
regulation of protein localization to nucleus GO:1900180 85 0.037
ventricular trabecula myocardium morphogenesis GO:0003222 1 0.037
response to cytokine GO:0034097 232 0.036
tissue morphogenesis GO:0048729 96 0.036
protein catabolic process GO:0030163 325 0.036
purine ribonucleoside metabolic process GO:0046128 437 0.035
vesicle mediated transport GO:0016192 371 0.035
microtubule cytoskeleton organization GO:0000226 176 0.035
regulation of epithelial cell proliferation GO:0050678 113 0.035
regeneration GO:0031099 4 0.035
regulation of intracellular transport GO:0032386 195 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
transmembrane transport GO:0055085 399 0.034
oocyte differentiation GO:0009994 2 0.034
response to bacterium GO:0009617 144 0.034
neuromuscular junction development GO:0007528 3 0.033
regulation of protein transport GO:0051223 213 0.033
cellular response to oxygen containing compound GO:1901701 276 0.033
intracellular protein transport GO:0006886 270 0.033
protein import GO:0017038 130 0.033
cellular ketone metabolic process GO:0042180 80 0.032
heart morphogenesis GO:0003007 48 0.032
cation transmembrane transport GO:0098655 238 0.032
regulation of innate immune response GO:0045088 97 0.032
regulation of microtubule cytoskeleton organization GO:0070507 61 0.032
myosin filament organization GO:0031033 2 0.031
viral process GO:0016032 146 0.031
nucleoside monophosphate metabolic process GO:0009123 191 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.030
Yeast
epithelial cell proliferation GO:0050673 128 0.030
protein targeting GO:0006605 187 0.030
segmentation GO:0035282 4 0.030
Fly
regulation of kinase activity GO:0043549 314 0.030
amine metabolic process GO:0009308 44 0.030
hindbrain development GO:0030902 3 0.030
chordate embryonic development GO:0043009 34 0.030
muscle tissue development GO:0060537 62 0.030
regulation of anatomical structure size GO:0090066 101 0.030
nucleocytoplasmic transport GO:0006913 176 0.029
regulation of intracellular protein transport GO:0033157 123 0.029
blood vessel morphogenesis GO:0048514 162 0.029
actin cytoskeleton organization GO:0030036 207 0.029
regulation of protein serine threonine kinase activity GO:0071900 179 0.029
protein localization to nucleus GO:0034504 136 0.028
behavioral response to ethanol GO:0048149 2 0.028
cardiac muscle tissue development GO:0048738 39 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
epithelial cell differentiation GO:0030855 141 0.028
multi organism reproductive process GO:0044703 54 0.028
positive regulation of mapk cascade GO:0043410 190 0.027
leukocyte differentiation GO:0002521 98 0.027
positive regulation of defense response GO:0031349 87 0.027
thyroid hormone metabolic process GO:0042403 4 0.027
reproductive structure development GO:0048608 55 0.027
fatty acid metabolic process GO:0006631 115 0.027
cellular response to lipid GO:0071396 127 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
striated muscle myosin thick filament assembly GO:0071688 2 0.026
determination of adult lifespan GO:0008340 2 0.026
rna export from nucleus GO:0006405 33 0.026
morphogenesis of an epithelium GO:0002009 60 0.026
regulation of neuron differentiation GO:0045664 70 0.026
protein import into nucleus GO:0006606 104 0.025
nuclear import GO:0051170 106 0.025
positive regulation of cell cycle GO:0045787 140 0.025
positive regulation of dendrite morphogenesis GO:0050775 3 0.025
embryonic placenta development GO:0001892 1 0.025
dephosphorylation GO:0016311 209 0.025
immune system development GO:0002520 195 0.024
gonad development GO:0008406 34 0.024
response to lipid GO:0033993 206 0.024
regulation of protein catabolic process GO:0042176 155 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.024
cellular response to interferon gamma GO:0071346 24 0.024
sister chromatid segregation GO:0000819 54 0.024
epidermal cell differentiation GO:0009913 45 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
negative regulation of epithelial cell proliferation GO:0050680 48 0.024
positive regulation of intracellular protein transport GO:0090316 76 0.023
multicellular organism reproduction GO:0032504 42 0.023
organelle fission GO:0048285 149 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
regulation of response to interferon gamma GO:0060330 7 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
negative regulation of defense response GO:0031348 47 0.023
branch elongation of an epithelium GO:0060602 3 0.023
negative regulation of immune system process GO:0002683 136 0.023
myeloid leukocyte differentiation GO:0002573 60 0.023
negative regulation of mapk cascade GO:0043409 56 0.023
central nervous system development GO:0007417 123 0.022
camera type eye development GO:0043010 25 0.022
response to light stimulus GO:0009416 87 0.022
regulation of dna metabolic process GO:0051052 153 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
epidermis development GO:0008544 59 0.022
tube closure GO:0060606 3 0.022
glycerolipid metabolic process GO:0046486 107 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
organophosphate biosynthetic process GO:0090407 163 0.022
muscle organ development GO:0007517 56 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.021
negative regulation of immune response GO:0050777 40 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
monocarboxylic acid metabolic process GO:0032787 185 0.021
striated muscle tissue development GO:0014706 59 0.021
system process GO:0003008 349 0.021
positive regulation of cellular component biogenesis GO:0044089 158 0.021
negative regulation of stem cell proliferation GO:2000647 3 0.021
ion transmembrane transport GO:0034220 338 0.021
regulation of g0 to g1 transition GO:0070316 2 0.021
stem cell proliferation GO:0072089 25 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
response to nutrient GO:0007584 20 0.021
Yeast
positive regulation of kinase activity GO:0033674 204 0.021
embryonic epithelial tube formation GO:0001838 4 0.021
embryonic morphogenesis GO:0048598 85 0.021
regulation of locomotion GO:0040012 329 0.021
negative regulation of growth GO:0045926 97 0.020
Yeast
hormone metabolic process GO:0042445 61 0.020
steroid metabolic process GO:0008202 94 0.020
mitotic sister chromatid segregation GO:0000070 53 0.020
angiogenesis GO:0001525 147 0.020
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.020
snrna 3 end processing GO:0034472 1 0.020
Fly
heart development GO:0007507 95 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
nuclear transport GO:0051169 179 0.020
nuclear export GO:0051168 69 0.019
response to alcohol GO:0097305 64 0.019
ribonucleotide catabolic process GO:0009261 405 0.019
chromosome segregation GO:0007059 114 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
regulation of meiotic cell cycle GO:0051445 4 0.019
cell cycle g1 s phase transition GO:0044843 80 0.019
Fly
regulation of cellular component size GO:0032535 82 0.019
striated muscle cell differentiation GO:0051146 43 0.019
nucleotide catabolic process GO:0009166 408 0.019
myosin filament assembly GO:0031034 2 0.019
cytokine mediated signaling pathway GO:0019221 109 0.018
response to thyroid hormone GO:0097066 9 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
regulation of membrane potential GO:0042391 95 0.018
hindlimb morphogenesis GO:0035137 2 0.018
regulation of cellular component movement GO:0051270 334 0.018
erk1 and erk2 cascade GO:0070371 104 0.018
spermatid development GO:0007286 4 0.018
regulation of nucleocytoplasmic transport GO:0046822 98 0.018
reproduction GO:0000003 63 0.018
Worm
regulation of cellular response to stress GO:0080135 244 0.018
regulation of meiosis GO:0040020 3 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
memory GO:0007613 3 0.017
mammary gland development GO:0030879 17 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
endocytosis GO:0006897 159 0.017
nucleoside catabolic process GO:0009164 408 0.017
sensory organ development GO:0007423 52 0.017
Fly
response to hormone GO:0009725 175 0.017
protein autophosphorylation GO:0046777 123 0.017
defense response to fungus GO:0050832 4 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
regulation of body fluid levels GO:0050878 99 0.017
response to oxidative stress GO:0006979 121 0.017
nitrogen compound transport GO:0071705 191 0.017
digestive system development GO:0055123 75 0.017
mitochondrial membrane organization GO:0007006 40 0.016
lens development in camera type eye GO:0002088 2 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
muscle cell differentiation GO:0042692 63 0.016
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
erythrocyte differentiation GO:0030218 28 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
axis elongation GO:0003401 4 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.016
protein polymerization GO:0051258 71 0.016
maintenance of location GO:0051235 112 0.016
cellular response to extracellular stimulus GO:0031668 72 0.016
Yeast
macromolecule methylation GO:0043414 97 0.016
regulation of map kinase activity GO:0043405 108 0.016
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
nuclear division GO:0000280 128 0.016
positive regulation of meiotic cell cycle GO:0051446 2 0.016
epithelial tube morphogenesis GO:0060562 38 0.015
negative regulation of protein modification process GO:0031400 200 0.015
regulation of neuron death GO:1901214 56 0.015
response to inorganic substance GO:0010035 127 0.015
regulation of cell migration GO:0030334 289 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
atp metabolic process GO:0046034 176 0.015
cell adhesion GO:0007155 325 0.015
response to organonitrogen compound GO:0010243 156 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
regulation of protein import into nucleus GO:0042306 78 0.015
double strand break repair GO:0006302 101 0.015
regulation of cell projection organization GO:0031344 107 0.015
organelle assembly GO:0070925 176 0.014
methylation GO:0032259 106 0.014
positive regulation of innate immune response GO:0045089 79 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
positive regulation of cell projection organization GO:0031346 64 0.014
regulation of nuclear division GO:0051783 65 0.014
embryonic appendage morphogenesis GO:0035113 9 0.014
limb development GO:0060173 23 0.014
atp catabolic process GO:0006200 157 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
nucleobase containing compound transport GO:0015931 51 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
single organism nuclear import GO:1902593 104 0.014
ribonucleoside catabolic process GO:0042454 406 0.014
multi organism cellular process GO:0044764 156 0.014
positive regulation of map kinase activity GO:0043406 80 0.014
metal ion transport GO:0030001 272 0.014
cellular amine metabolic process GO:0044106 41 0.014
negative regulation of cell death GO:0060548 345 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.013
digestive tract development GO:0048565 75 0.013
appendage development GO:0048736 23 0.013
Fly
response to radiation GO:0009314 151 0.013
response to organic cyclic compound GO:0014070 204 0.013
protein targeting to nucleus GO:0044744 104 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
taxis GO:0042330 157 0.013
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
negative regulation of phagocytosis engulfment GO:0060101 1 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
biological adhesion GO:0022610 331 0.013
endosomal transport GO:0016197 129 0.013
regulation of epithelial cell migration GO:0010632 93 0.013
cellular hormone metabolic process GO:0034754 41 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
cell cell signaling involved in cell fate commitment GO:0045168 5 0.013
organelle localization GO:0051640 84 0.013
epidermal growth factor receptor signaling pathway GO:0007173 39 0.013
protein processing GO:0016485 226 0.013
regulation of homeostatic process GO:0032844 121 0.013
chromatin organization GO:0006325 351 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
cellular response to nutrient GO:0031670 12 0.013
Yeast
microtubule polymerization or depolymerization GO:0031109 37 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
activation of protein kinase activity GO:0032147 90 0.012
eye photoreceptor cell differentiation GO:0001754 2 0.012
regulation of neuron projection development GO:0010975 57 0.012
response to glucagon GO:0033762 1 0.012
cellular response to vitamin GO:0071295 6 0.012
protein maturation GO:0051604 233 0.012
protein glycosylation GO:0006486 62 0.012
oocyte development GO:0048599 1 0.012
hemopoiesis GO:0030097 180 0.012
tube development GO:0035295 125 0.012
regulation of multi organism process GO:0043900 157 0.012
hippocampus development GO:0021766 1 0.012
endomembrane system organization GO:0010256 196 0.012
head development GO:0060322 108 0.012
lactation GO:0007595 3 0.012
cell part morphogenesis GO:0032990 137 0.012
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.012
Fly
protein ubiquitination GO:0016567 314 0.012
regulation of protein complex assembly GO:0043254 147 0.012
skin development GO:0043588 76 0.012
defense response to gram negative bacterium GO:0050829 14 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
regulation of secretion GO:0051046 194 0.012
response to nutrient levels GO:0031667 81 0.012
Yeast
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
positive regulation of cell cycle process GO:0090068 106 0.011
regulation of protein stability GO:0031647 87 0.011
Yeast
positive regulation of neurogenesis GO:0050769 49 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
regulation of neuron apoptotic process GO:0043523 35 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
dna replication GO:0006260 116 0.011
cell substrate adhesion GO:0031589 132 0.011
regulation of cell division GO:0051302 116 0.011
positive regulation of catabolic process GO:0009896 310 0.011
actomyosin structure organization GO:0031032 59 0.011
cellular modified amino acid metabolic process GO:0006575 64 0.011
neural tube closure GO:0001843 3 0.011
positive regulation of organelle organization GO:0010638 195 0.011
phagocytosis GO:0006909 42 0.011
ameboidal type cell migration GO:0001667 135 0.011
response to acid chemical GO:0001101 66 0.011
rna interference GO:0016246 4 0.010
single organism cell adhesion GO:0098602 179 0.010
digestive tract morphogenesis GO:0048546 56 0.010
developmental growth GO:0048589 48 0.010
reproductive system development GO:0061458 56 0.010
regulation of proteolysis GO:0030162 293 0.010
regulation of peptidase activity GO:0052547 180 0.010
positive regulation of synaptic transmission GO:0050806 4 0.010
regulation of dna repair GO:0006282 47 0.010
protein dna complex assembly GO:0065004 64 0.010
microtubule polymerization GO:0046785 18 0.010
regulation of cell motility GO:2000145 299 0.010
positive regulation of cell development GO:0010720 92 0.010
organophosphate catabolic process GO:0046434 430 0.010
negative regulation of transferase activity GO:0051348 124 0.010
ribonucleoprotein complex export from nucleus GO:0071426 4 0.010
positive regulation of epithelial cell differentiation GO:0030858 14 0.010
cell fate determination GO:0001709 3 0.010
monovalent inorganic cation transport GO:0015672 128 0.010
response to uv GO:0009411 73 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010

CDK8 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.011
disease of cellular proliferation DOID:14566 174 0.011
musculoskeletal system disease DOID:17 223 0.010
connective tissue disease DOID:65 109 0.010