|
|
regulation of cell cycle
|
GO:0051726 |
393 |
1.000
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
1.000
|
Mouse |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
1.000
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
1.000
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
1.000
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
1.000
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
1.000
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
1.000
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
1.000
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
1.000
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.999
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.999
|
Human Mouse |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.999
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.999
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.999
|
Human |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.999
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.999
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.999
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.999
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.999
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.999
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.999
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.998
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.998
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.997
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.997
|
Human Mouse |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.997
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.996
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.996
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.995
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.995
|
Human |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.995
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.995
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.995
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.992
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.992
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.992
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.991
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
4 |
0.991
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.990
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.990
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.990
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.989
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.989
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.988
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.988
|
Human |
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.988
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.987
|
Human |
|
|
gland development
|
GO:0048732 |
48 |
0.986
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.986
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.986
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.983
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.983
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.983
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.982
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.980
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.979
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.979
|
Human Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.979
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.978
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.977
|
Human |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.977
|
|
|
|
neutrophil clearance
|
GO:0097350 |
1 |
0.976
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.976
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.976
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.976
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.975
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.974
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.972
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.972
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.971
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.971
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.971
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.970
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.965
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.965
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.964
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.964
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.964
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.962
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.960
|
Human |
|
|
protein heterotetramerization
|
GO:0051290 |
3 |
0.960
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.955
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.955
|
|
|
|
positive regulation of g2 m transition of mitotic cell cycle
|
GO:0010971 |
8 |
0.952
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.952
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.952
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.950
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.949
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.948
|
Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.946
|
|
|
|
glandular epithelial cell development
|
GO:0002068 |
5 |
0.944
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.941
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.939
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.936
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.936
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.935
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.935
|
Mouse |
|
|
cell aging
|
GO:0007569 |
52 |
0.933
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.932
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.932
|
Mouse |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.930
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.928
|
Human |
|
|
positive regulation of cell cycle g2 m phase transition
|
GO:1902751 |
8 |
0.927
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.927
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.926
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.924
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.922
|
Mouse |
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.920
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.919
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.918
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.918
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.915
|
Human |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.913
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.912
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.911
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.911
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.909
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.909
|
|
|
|
peptide cross linking
|
GO:0018149 |
12 |
0.900
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.900
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.898
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.898
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.895
|
Mouse |
|
|
secretion
|
GO:0046903 |
254 |
0.894
|
|
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.894
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.892
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.891
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.886
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.883
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.882
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.881
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.879
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.877
|
|
|
|
osteoclast development
|
GO:0036035 |
2 |
0.877
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.876
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.876
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.874
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.871
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.871
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.870
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.867
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.866
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.864
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.862
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.860
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.860
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.858
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.858
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.856
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.855
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.851
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.850
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.848
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.847
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.847
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.845
|
|
|
|
negative regulation of interleukin 8 secretion
|
GO:2000483 |
2 |
0.842
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.840
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.837
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.837
|
Human |
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.833
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.829
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.825
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.818
|
Human |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.817
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.815
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.811
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.809
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.808
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.808
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.804
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.803
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.799
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.798
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.798
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.798
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.795
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.794
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.791
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.790
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.787
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.787
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.785
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.785
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.780
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.778
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.778
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.774
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.774
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.770
|
|
|
|
membrane raft assembly
|
GO:0001765 |
7 |
0.768
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.765
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.762
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.760
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.760
|
Mouse |
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.757
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.756
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.754
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.751
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.747
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.745
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.743
|
Human Mouse |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.742
|
Mouse |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.742
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.735
|
|
|
|
neutrophil homeostasis
|
GO:0001780 |
3 |
0.733
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.727
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.726
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.725
|
|
|
|
membrane biogenesis
|
GO:0044091 |
13 |
0.725
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.722
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.721
|
|
|
|
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering
|
GO:0097113 |
1 |
0.721
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.710
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
22 |
0.710
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.710
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.709
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.705
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.701
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.700
|
Human |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.700
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.692
|
Mouse |
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.690
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.689
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.686
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.683
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.682
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.682
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.681
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.681
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
5 |
0.678
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.677
|
Human |
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.676
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.674
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.673
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.663
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.662
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.661
|
Human |
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.658
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.658
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.654
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.651
|
|
|
|
growth
|
GO:0040007 |
202 |
0.648
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.648
|
|
|
|
cell dedifferentiation
|
GO:0043697 |
1 |
0.647
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.645
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.641
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.640
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.633
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.631
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.631
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.629
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.625
|
Human |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.622
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.622
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.622
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.613
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.611
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.610
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.610
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.603
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.599
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.596
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.593
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.592
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.589
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.587
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.585
|
|
|
|
system process
|
GO:0003008 |
349 |
0.584
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.584
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.569
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.567
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.566
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.566
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.561
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.561
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.559
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.558
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.557
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.557
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.556
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.553
|
|
|
|
type b pancreatic cell differentiation
|
GO:0003309 |
5 |
0.552
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.552
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.551
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.550
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.546
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.544
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.541
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.536
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.536
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.534
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.532
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.528
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.524
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.522
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.520
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.519
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.519
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.514
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.514
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.511
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.509
|
|
|
|
negative regulation of cytokine secretion
|
GO:0050710 |
20 |
0.507
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.503
|
Mouse |
|
|
immune response
|
GO:0006955 |
307 |
0.503
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.502
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.501
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.498
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.498
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.487
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.485
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.485
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.483
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.479
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.479
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.467
|
|
|
|
response to uv a
|
GO:0070141 |
6 |
0.465
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.464
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
10 |
0.461
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.458
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.457
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.457
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.457
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.456
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
15 |
0.456
|
Mouse |
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.455
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.455
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.451
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.451
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.447
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.445
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.444
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.442
|
|
|
|
membrane raft organization
|
GO:0031579 |
10 |
0.441
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.441
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.440
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.434
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.433
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.431
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.430
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.425
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.424
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.422
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.420
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.420
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.420
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.419
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.417
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.416
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.414
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.409
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.408
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.407
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.401
|
Human Mouse |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.397
|
|
|
|
regulation of vesicle fusion
|
GO:0031338 |
5 |
0.396
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.395
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.391
|
|
|
|
regulation of cellular senescence
|
GO:2000772 |
13 |
0.391
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.388
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.387
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.385
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.381
|
Human |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.374
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.371
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.370
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.366
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.365
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
13 |
0.363
|
|
|
|
membrane assembly
|
GO:0071709 |
10 |
0.361
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.358
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.358
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.354
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.353
|
|
|
|
water homeostasis
|
GO:0030104 |
14 |
0.352
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.350
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.350
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.349
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.348
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.348
|
Mouse |
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.347
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.346
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.346
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.344
|
Mouse |
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.337
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.336
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.334
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.332
|
Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.330
|
|
|
|
phosphorylation of rna polymerase ii c terminal domain
|
GO:0070816 |
3 |
0.328
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.327
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.326
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.325
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.323
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.321
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.319
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.313
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.310
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.307
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.306
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.305
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.305
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.305
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.304
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.300
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.299
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.298
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.298
|
Mouse |
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.296
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.295
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.295
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.294
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.292
|
|
|
|
cellular response to antibiotic
|
GO:0071236 |
1 |
0.292
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.291
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.289
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.285
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.284
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.282
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.281
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.281
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.280
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.278
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.278
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.276
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.275
|
|
|
|
positive regulation of p38mapk cascade
|
GO:1900745 |
8 |
0.274
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.273
|
|
|
|
dedifferentiation
|
GO:0043696 |
1 |
0.269
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.267
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.265
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.262
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.262
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.259
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.258
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.258
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.257
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.257
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.257
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.256
|
Mouse |
|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
12 |
0.255
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.254
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.253
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.251
|
|
|
|
negative regulation of cellular carbohydrate metabolic process
|
GO:0010677 |
14 |
0.250
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.248
|
|
|
|
regulation of cell aging
|
GO:0090342 |
18 |
0.247
|
|
|
|
negative regulation of chromosome segregation
|
GO:0051985 |
18 |
0.247
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.245
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.244
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.243
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.242
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.241
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.240
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.238
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.237
|
|
|
|
cellular response to xenobiotic stimulus
|
GO:0071466 |
29 |
0.237
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.237
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.234
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.233
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.233
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.232
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.230
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.229
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.229
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.228
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.228
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.226
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.223
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.223
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.220
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.219
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.219
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.218
|
Mouse |
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.218
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.211
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.211
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.211
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.211
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.210
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.206
|
Mouse |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.205
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.203
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.203
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.202
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.201
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.201
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.200
|
|
|
|
aging
|
GO:0007568 |
66 |
0.200
|
|
|
|
neutrophil aggregation
|
GO:0070488 |
2 |
0.199
|
|
