|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.990
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.964
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.963
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.929
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.927
|
Human Mouse |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.906
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.893
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.878
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.866
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.847
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.834
|
Mouse |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.812
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.807
|
Human |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.796
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.788
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.781
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.765
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.763
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.753
|
Human |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.750
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.749
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.747
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.742
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.732
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.727
|
Human |
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.708
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.700
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.691
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.680
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.663
|
Human |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.659
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.647
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.638
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.622
|
Mouse |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.615
|
Human |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.598
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.585
|
Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.584
|
Mouse |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.582
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.577
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.566
|
Human |
|
|
neutral lipid catabolic process
|
GO:0046461 |
12 |
0.559
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.557
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.544
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.520
|
Mouse |
|
|
protein processing
|
GO:0016485 |
226 |
0.504
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.500
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.496
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.494
|
Human |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.487
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.481
|
Mouse |
|
|
stem cell development
|
GO:0048864 |
69 |
0.481
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.480
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.459
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.453
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.444
|
Human |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.443
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.439
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.439
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.432
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.431
|
Mouse |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.419
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.417
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.414
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.412
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.409
|
Human Mouse |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.404
|
Human |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.404
|
Mouse |
|
|
organelle fission
|
GO:0048285 |
149 |
0.397
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.394
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
0.391
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.386
|
Human |
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.386
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.384
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.360
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.351
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.343
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.342
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.340
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.324
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.322
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.319
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.318
|
Human |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.317
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.316
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.314
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.314
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.302
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.299
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.297
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.297
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.292
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.290
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.288
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.287
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.286
|
Human |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.283
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.281
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.279
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.273
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.269
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.263
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.262
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.256
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.250
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.249
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.243
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.243
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.242
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.241
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.238
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.237
|
|
|
|
memory
|
GO:0007613 |
3 |
0.236
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.235
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.233
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.226
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.225
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.218
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.215
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.214
|
Mouse |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.213
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.213
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.213
|
Human |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.209
|
Human |
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.204
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.203
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.197
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.196
|
|
|
|
glandular epithelial cell development
|
GO:0002068 |
5 |
0.192
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.190
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.189
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.186
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.186
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.183
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.182
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.181
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.179
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.177
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.171
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.154
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.154
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.152
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.148
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.143
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.141
|
Human |
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.139
|
|
|
|
type b pancreatic cell differentiation
|
GO:0003309 |
5 |
0.137
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.133
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.132
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.131
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.130
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.130
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.130
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
151 |
0.129
|
Human |
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.127
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.126
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.126
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.124
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.124
|
Mouse |
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.123
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.123
|
Human |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.120
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.119
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.119
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.115
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.115
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.115
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.112
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.110
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.109
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.109
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.107
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.105
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.105
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.104
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.104
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.103
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.103
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.103
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.103
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.102
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.101
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.101
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.101
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.100
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.099
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.099
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.099
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.099
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.098
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.096
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.096
|
|
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
22 |
0.092
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.091
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.087
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.087
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.087
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.087
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.086
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.085
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.084
|
|
|
|
glandular epithelial cell differentiation
|
GO:0002067 |
6 |
0.083
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.083
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.082
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.081
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.081
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.081
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.080
|
Human |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.078
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.076
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.074
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.074
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.073
|
Human |
|
|
membrane organization
|
GO:0061024 |
292 |
0.073
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.073
|
|
|
|
positive regulation of cell cycle g2 m phase transition
|
GO:1902751 |
8 |
0.073
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.073
|
|
|
|
positive regulation of g2 m transition of mitotic cell cycle
|
GO:0010971 |
8 |
0.072
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.072
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.072
|
Human |
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.072
|
Human |
|
|
negative regulation of meiotic cell cycle
|
GO:0051447 |
2 |
0.070
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.070
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.069
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.069
|
|
|
|
negative regulation of cardiac muscle cell apoptotic process
|
GO:0010667 |
2 |
0.068
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.067
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.066
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.064
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.064
|
Mouse |
|
|
regulation of protein import into nucleus translocation
|
GO:0033158 |
10 |
0.064
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.064
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.063
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.063
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.062
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.061
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.061
|
|
|
|
dna replication initiation
|
GO:0006270 |
6 |
0.061
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.061
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.060
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.059
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.059
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
15 |
0.058
|
Mouse |
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.057
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.056
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.056
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.055
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.055
|
|
|
|
system process
|
GO:0003008 |
349 |
0.055
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.055
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.055
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.054
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.054
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.054
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.054
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.053
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.053
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.053
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.053
|
|
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.052
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.052
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.051
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.051
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.051
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.051
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.051
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.051
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.051
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.050
|
|
|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
0.050
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.050
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.050
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.050
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.050
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.050
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.049
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.049
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.049
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.049
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.048
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.047
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.047
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.047
|
|
|
|
dna synthesis involved in dna repair
|
GO:0000731 |
6 |
0.047
|
|
|
|
aging
|
GO:0007568 |
66 |
0.047
|
Human |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.047
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.046
|
Human |
|
|
response to ketone
|
GO:1901654 |
19 |
0.045
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.045
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.045
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.045
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.044
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.043
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.043
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.043
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.043
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.043
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.043
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.043
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.043
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.043
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.043
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.042
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.042
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.041
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.041
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.041
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.040
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.040
|
Mouse |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.040
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.040
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.039
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.039
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.039
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.039
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.038
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.038
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.038
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.038
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.038
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.038
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.038
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.038
|
Mouse |
|
|
behavior
|
GO:0007610 |
112 |
0.038
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.037
|
|
|
|
negative regulation of striated muscle cell apoptotic process
|
GO:0010664 |
2 |
0.037
|
|
|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
12 |
0.037
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.037
|
Mouse |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.037
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.036
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.036
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.036
|
Mouse |
|
|
secretion
|
GO:0046903 |
254 |
0.036
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.035
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.035
|
|
|
|
axoneme assembly
|
GO:0035082 |
3 |
0.035
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.035
|
Human |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.035
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.034
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.034
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.034
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.034
|
Mouse |
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.034
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.034
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.034
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.034
|
Human |
|
|
male meiosis
|
GO:0007140 |
1 |
0.034
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.033
|
Mouse |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.033
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.032
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.032
|
Human |
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.032
|
|
|
|
dna templated transcription termination
|
GO:0006353 |
3 |
0.032
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.032
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.032
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.031
|
|
|
|
response to uv a
|
GO:0070141 |
6 |
0.031
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.031
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.031
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.031
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.031
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.030
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.030
|
Mouse |
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.030
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.030
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.030
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.030
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.030
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.029
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.029
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.029
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.029
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.029
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.029
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.029
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.028
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.028
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.027
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.027
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.027
|
|
|
|
negative regulation of cell division
|
GO:0051782 |
31 |
0.027
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.027
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.027
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.027
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.027
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.027
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.027
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.027
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.027
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.027
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.026
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.026
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.026
|
|
|
|
growth
|
GO:0040007 |
202 |
0.026
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.026
|
Mouse |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.026
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.026
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.026
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.026
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.026
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.026
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.026
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.026
|
|
|
|
dendritic spine organization
|
GO:0097061 |
4 |
0.026
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.026
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.025
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.025
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.025
|
Human |
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
9 |
0.025
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.025
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.025
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.025
|
Human |
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.024
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.024
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.024
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.024
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.024
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.024
|
|
|
|
response to ethanol
|
GO:0045471 |
11 |
0.024
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.023
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.023
|
Mouse |
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.023
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.023
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.023
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.023
|
Mouse |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.023
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
6 |
0.023
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.023
|
Mouse |
|
|
compound eye development
|
GO:0048749 |
1 |
0.023
|
|
|
|
phosphorylation of rna polymerase ii c terminal domain
|
GO:0070816 |
3 |
0.023
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.023
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.023
|
|
|
|
response to dexamethasone
|
GO:0071548 |
1 |
0.023
|
|
|
|
cyclin catabolic process
|
GO:0008054 |
6 |
0.022
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.022
|
|
|
|
response to magnesium ion
|
GO:0032026 |
3 |
0.022
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.022
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.022
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.022
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.022
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.021
|
Human |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.021
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.021
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.021
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.021
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.021
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.021
|
|
|
|
negative regulation of sister chromatid segregation
|
GO:0033046 |
17 |
0.021
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.021
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.021
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.021
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.021
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.021
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.021
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.020
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.020
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.020
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.020
|
|
|
|
mitotic metaphase plate congression
|
GO:0007080 |
14 |
0.020
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.020
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.020
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.020
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.020
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.020
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.020
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.020
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.020
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.020
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.019
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.019
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.019
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.019
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.019
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.019
|
Human |
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.019
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.019
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.019
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.019
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.019
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.019
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.019
|
|
|
|
regulation of cellular senescence
|
GO:2000772 |
13 |
0.018
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.018
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.018
|
|
|
|
protein demethylation
|
GO:0006482 |
17 |
0.018
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.018
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.018
|
|
