Homo sapiens

56 known processes

CENPJ

centromere protein J

(Aliases: Sas-4,SASS4,MCPH6,CPAP,MGC142224,MGC131581,MGC131582,MGC142222,LIP1,BM032,SCKL4,LAP)

CENPJ biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axoneme assembly GO:0035082 3 0.998
cilium morphogenesis GO:0060271 75 0.997
cilium assembly GO:0042384 63 0.972
asymmetric neuroblast division GO:0055059 1 0.964
centriole replication GO:0007099 13 0.905
microtubule organizing center organization GO:0031023 62 0.894
somatic stem cell division GO:0048103 1 0.869
centrosome cycle GO:0007098 32 0.826
cilium organization GO:0044782 68 0.800
microtubule cytoskeleton organization GO:0000226 176 0.776
regulation of microtubule cytoskeleton organization GO:0070507 61 0.756
centrosome organization GO:0051297 58 0.715
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.675
microtubule polymerization or depolymerization GO:0031109 37 0.588
centrosome duplication GO:0051298 28 0.558
cell morphogenesis GO:0000902 296 0.476
protein localization to organelle GO:0033365 280 0.473
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.473
positive regulation of cell cycle GO:0045787 140 0.469
cell projection assembly GO:0030031 126 0.465
cellular component assembly involved in morphogenesis GO:0010927 73 0.437
regulation of protein catabolic process GO:0042176 155 0.378
cell projection organization GO:0030030 252 0.350
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.344
cell division GO:0051301 168 0.309
nuclear division GO:0000280 128 0.305
anatomical structure formation involved in morphogenesis GO:0048646 284 0.290
embryonic epithelial tube formation GO:0001838 4 0.270
spindle checkpoint GO:0031577 26 0.266
regulation of cytoskeleton organization GO:0051493 177 0.258
cell projection morphogenesis GO:0048858 129 0.253
protein catabolic process GO:0030163 325 0.249
cellular component morphogenesis GO:0032989 314 0.247
neuronal stem cell division GO:0036445 1 0.246
negative regulation of cell cycle process GO:0010948 121 0.214
neuroblast division GO:0055057 1 0.212
mitotic cell cycle GO:0000278 326 0.212
negative regulation of organelle organization GO:0010639 126 0.198
spermatid differentiation GO:0048515 4 0.190
organelle fission GO:0048285 149 0.189
asymmetric stem cell division GO:0098722 1 0.189
centriole assembly GO:0098534 14 0.179
regulation of cell cycle phase transition GO:1901987 126 0.174
protein complex disassembly GO:0043241 52 0.169
embryonic placenta development GO:0001892 1 0.164
regulation of centrosome cycle GO:0046605 15 0.153
centriole centriole cohesion GO:0010457 8 0.150
microtubule based process GO:0007017 210 0.138
positive regulation of protein kinase activity GO:0045860 190 0.138
regulation of centrosome duplication GO:0010824 14 0.136
mitotic cell cycle process GO:1903047 286 0.127
organelle assembly GO:0070925 176 0.126
neuroblast proliferation GO:0007405 4 0.126
cell part morphogenesis GO:0032990 137 0.125
regulation of cell cycle GO:0051726 393 0.125
embryonic organ development GO:0048568 36 0.123
anatomical structure homeostasis GO:0060249 100 0.122
neural tube development GO:0021915 9 0.114
macromolecular complex disassembly GO:0032984 60 0.110
positive regulation of cellular component organization GO:0051130 376 0.108
positive regulation of organelle organization GO:0010638 195 0.107
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.098
cellular component disassembly GO:0022411 92 0.098
smoothened signaling pathway GO:0007224 14 0.096
mitotic nuclear division GO:0007067 119 0.095
regulation of organelle assembly GO:1902115 40 0.091
cell cell signaling GO:0007267 155 0.091
cell cycle phase transition GO:0044770 173 0.088
cardiovascular system development GO:0072358 262 0.083
negative regulation of cytoskeleton organization GO:0051494 45 0.082
nucleoside triphosphate catabolic process GO:0009143 394 0.078
regulation of proteolysis GO:0030162 293 0.077
canonical wnt signaling pathway GO:0060070 116 0.077
positive regulation of kinase activity GO:0033674 204 0.076
positive regulation of protein catabolic process GO:0045732 75 0.074
stem cell division GO:0017145 2 0.072
negative regulation of cell cycle phase transition GO:1901988 89 0.069
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.069
circulatory system development GO:0072359 262 0.063
morphogenesis of embryonic epithelium GO:0016331 4 0.062
modification dependent protein catabolic process GO:0019941 209 0.061
regulation of mitotic cell cycle phase transition GO:1901990 118 0.059
heart morphogenesis GO:0003007 48 0.058
ribonucleoside triphosphate catabolic process GO:0009203 391 0.056
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.056
positive regulation of cellular component biogenesis GO:0044089 158 0.055
ribonucleotide catabolic process GO:0009261 405 0.054
heart development GO:0007507 95 0.053
protein processing GO:0016485 226 0.052
regulation of mitotic cell cycle GO:0007346 189 0.051
mitotic centrosome separation GO:0007100 1 0.050
regulation of transferase activity GO:0051338 355 0.049
purine containing compound catabolic process GO:0072523 411 0.048
cellular macromolecule catabolic process GO:0044265 380 0.046
nucleoside phosphate catabolic process GO:1901292 412 0.046
mitotic spindle checkpoint GO:0071174 18 0.045
negative regulation of programmed cell death GO:0043069 321 0.045
organ morphogenesis GO:0009887 147 0.043
regulation of canonical wnt signaling pathway GO:0060828 88 0.043
cellular protein complex assembly GO:0043623 188 0.043
nervous system development GO:0007399 293 0.042
centrosome separation GO:0051299 3 0.042
embryonic morphogenesis GO:0048598 85 0.041
positive regulation of cell cycle process GO:0090068 106 0.041
regulation of cellular protein catabolic process GO:1903362 96 0.040
peptidyl threonine modification GO:0018210 45 0.040
negative regulation of apoptotic process GO:0043066 316 0.040
regulation of microtubule based process GO:0032886 74 0.038
spindle organization GO:0007051 53 0.038
head development GO:0060322 108 0.038
regulation of cellular ketone metabolic process GO:0010565 50 0.038
generation of neurons GO:0048699 152 0.036
negative regulation of multicellular organismal process GO:0051241 317 0.036
primary neural tube formation GO:0014020 3 0.036
purine nucleotide catabolic process GO:0006195 405 0.036
cellular protein catabolic process GO:0044257 261 0.036
chromosome segregation GO:0007059 114 0.036
central nervous system development GO:0007417 123 0.035
neural tube formation GO:0001841 3 0.035
nucleoside triphosphate metabolic process GO:0009141 422 0.034
heart looping GO:0001947 7 0.034
organophosphate catabolic process GO:0046434 430 0.033
negative regulation of protein catabolic process GO:0042177 59 0.033
negative regulation of catabolic process GO:0009895 104 0.033
regulation of establishment of protein localization GO:0070201 242 0.033
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.032
protein maturation GO:0051604 233 0.032
posttranscriptional regulation of gene expression GO:0010608 213 0.032
cellular ketone metabolic process GO:0042180 80 0.031
dna catabolic process GO:0006308 49 0.031
regulation of cell motility GO:2000145 299 0.031
ras protein signal transduction GO:0007265 73 0.031
growth GO:0040007 202 0.031
regulation of gtp catabolic process GO:0033124 180 0.031
regulation of cellular component biogenesis GO:0044087 281 0.030
negative regulation of protein depolymerization GO:1901880 17 0.030
positive regulation of apoptotic process GO:0043065 246 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.029
negative regulation of cellular component organization GO:0051129 235 0.029
neural tube closure GO:0001843 3 0.029
positive regulation of dna metabolic process GO:0051054 73 0.028
regulation of protein stability GO:0031647 87 0.028
protein localization to chromosome GO:0034502 30 0.028
purine ribonucleoside catabolic process GO:0046130 398 0.028
ribonucleoside catabolic process GO:0042454 406 0.027
regulation of apoptotic signaling pathway GO:2001233 175 0.027
amine metabolic process GO:0009308 44 0.026
protein ubiquitination GO:0016567 314 0.026
cellular amino acid metabolic process GO:0006520 116 0.026
regulation of chromosome segregation GO:0051983 44 0.026
positive regulation of cytoskeleton organization GO:0051495 83 0.025
regulation of microtubule depolymerization GO:0031114 12 0.025
gtp metabolic process GO:0046039 239 0.025
mitotic cell cycle checkpoint GO:0007093 68 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
regulation of protein complex disassembly GO:0043244 28 0.025
negative regulation of protein metabolic process GO:0051248 391 0.025
apoptotic signaling pathway GO:0097190 268 0.025
regulation of protein processing GO:0070613 150 0.025
wnt signaling pathway GO:0016055 156 0.024
biological adhesion GO:0022610 331 0.024
negative regulation of protein complex disassembly GO:0043242 20 0.024
regulation of proteasomal protein catabolic process GO:0061136 87 0.024
cell adhesion GO:0007155 325 0.024
ubiquitin dependent protein catabolic process GO:0006511 206 0.024
regulation of cell cycle process GO:0010564 266 0.024
single organism reproductive process GO:0044702 98 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
secretion GO:0046903 254 0.024
regulation of cellular component movement GO:0051270 334 0.023
response to cytokine GO:0034097 232 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
atp metabolic process GO:0046034 176 0.022
regulation of kinase activity GO:0043549 314 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
negative regulation of cell cycle GO:0045786 193 0.022
male meiosis GO:0007140 1 0.022
regulation of gtpase activity GO:0043087 180 0.022
purine ribonucleoside metabolic process GO:0046128 437 0.022
negative regulation of proteolysis GO:0045861 132 0.022
regulation of protein transport GO:0051223 213 0.021
regulation of protein complex assembly GO:0043254 147 0.021
positive regulation of organelle assembly GO:1902117 17 0.021
negative regulation of cellular protein catabolic process GO:1903363 38 0.021
negative regulation of cellular catabolic process GO:0031330 83 0.021
membrane organization GO:0061024 292 0.021
regulation of wnt signaling pathway GO:0030111 123 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
somatic muscle development GO:0007525 1 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
determination of adult lifespan GO:0008340 2 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
axon cargo transport GO:0008088 2 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
cellular protein complex disassembly GO:0043624 36 0.019
neuromuscular junction development GO:0007528 3 0.019
positive regulation of catabolic process GO:0009896 310 0.019
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
cytoplasmic transport GO:0016482 379 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
negative regulation of protein maturation GO:1903318 142 0.019
ribonucleoside monophosphate catabolic process GO:0009158 158 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
positive regulation of wnt signaling pathway GO:0030177 54 0.019
negative regulation of developmental process GO:0051093 247 0.019
negative regulation of microtubule depolymerization GO:0007026 12 0.019
regulation of cytoplasmic transport GO:1903649 149 0.019
guanosine containing compound metabolic process GO:1901068 244 0.018
rho protein signal transduction GO:0007266 26 0.018
specification of symmetry GO:0009799 16 0.018
reproductive process GO:0022414 106 0.018
double strand break repair GO:0006302 101 0.018
negative regulation of dna binding GO:0043392 18 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
single organism membrane organization GO:0044802 268 0.017
negative regulation of protein complex assembly GO:0031333 43 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
embryonic pattern specification GO:0009880 5 0.017
forebrain development GO:0030900 26 0.017
neuron cellular homeostasis GO:0070050 3 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
regulation of binding GO:0051098 111 0.016
regulation of protein kinase activity GO:0045859 289 0.016
positive regulation of transferase activity GO:0051347 227 0.016
single organism cellular localization GO:1902580 332 0.016
positive regulation of cell death GO:0010942 263 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
regulation of protein localization GO:0032880 296 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
regulation of protein maturation GO:1903317 150 0.016
protein autophosphorylation GO:0046777 123 0.016
regulation of secretion by cell GO:1903530 177 0.016
negative regulation of transferase activity GO:0051348 124 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
regulation of cytokine production GO:0001817 232 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
determination of left right symmetry GO:0007368 11 0.016
regulation of intracellular protein transport GO:0033157 123 0.015
mitotic spindle organization GO:0007052 27 0.015
tube closure GO:0060606 3 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
cell cycle checkpoint GO:0000075 117 0.015
negative regulation of protein processing GO:0010955 142 0.015
regulation of response to external stimulus GO:0032101 222 0.015
lipid metabolic process GO:0006629 381 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
carbohydrate metabolic process GO:0005975 207 0.015
protein adp ribosylation GO:0006471 9 0.015
protein localization to microtubule cytoskeleton GO:0072698 10 0.014
microtubule bundle formation GO:0001578 15 0.014
protein polyubiquitination GO:0000209 110 0.014
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
nuclear transport GO:0051169 179 0.014
regulation of dna replication GO:0006275 68 0.014
protein import GO:0017038 130 0.014
double strand break repair via homologous recombination GO:0000724 50 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.013
glycosylation GO:0070085 71 0.013
positive regulation of mitotic cell cycle GO:0045931 60 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
positive regulation of immune system process GO:0002684 283 0.013
oocyte development GO:0048599 1 0.013
protein targeting GO:0006605 187 0.013
regulation of locomotion GO:0040012 329 0.013
meiosis i GO:0007127 4 0.013
determination of bilateral symmetry GO:0009855 15 0.013
epithelial tube morphogenesis GO:0060562 38 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
regulation of defense response GO:0031347 154 0.012
oxidation reduction process GO:0055114 396 0.012
multicellular organism reproduction GO:0032504 42 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
protein targeting to nucleus GO:0044744 104 0.012
tissue regeneration GO:0042246 3 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
neurogenesis GO:0022008 169 0.012
glycoprotein metabolic process GO:0009100 110 0.012
gtp catabolic process GO:0006184 237 0.012
regulation of intracellular transport GO:0032386 195 0.012
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.012
regulation of growth GO:0040008 165 0.012
positive regulation of transport GO:0051050 336 0.012
cell substrate adhesion GO:0031589 132 0.012
response to abiotic stimulus GO:0009628 336 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
reciprocal meiotic recombination GO:0007131 4 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
developmental process involved in reproduction GO:0003006 66 0.011
cellular homeostasis GO:0019725 196 0.011
positive regulation of cellular amine metabolic process GO:0033240 7 0.011
cellular amine metabolic process GO:0044106 41 0.011
single organism nuclear import GO:1902593 104 0.011
compound eye development GO:0048749 1 0.011
mitotic sister chromatid separation GO:0051306 18 0.011
sex determination GO:0007530 3 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.011
intracellular protein transport GO:0006886 270 0.011
endomembrane system organization GO:0010256 196 0.011
positive regulation of cytoplasmic transport GO:1903651 82 0.011
macromolecule glycosylation GO:0043413 63 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
cell activation GO:0001775 213 0.011
multicellular organismal aging GO:0010259 3 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
regulation of cell growth GO:0001558 135 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
cell growth GO:0016049 160 0.011
regulation of cell migration GO:0030334 289 0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
regulation of nuclear division GO:0051783 65 0.010
negative regulation of cell motility GO:2000146 104 0.010
response to fungus GO:0009620 4 0.010
negative regulation of cell death GO:0060548 345 0.010
methylation GO:0032259 106 0.010
regulation of immune response GO:0050776 201 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
tissue morphogenesis GO:0048729 96 0.010
early endosome to late endosome transport GO:0045022 21 0.010
rna processing GO:0006396 255 0.010
protein glycosylation GO:0006486 62 0.010
positive regulation of intracellular transport GO:0032388 104 0.010

CENPJ disease predictions

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 41 0.417
congenital nervous system abnormality DOID:2490 21 0.417
immune system disease DOID:2914 155 0.106
cancer DOID:162 167 0.021
disease of cellular proliferation DOID:14566 174 0.021
organ system cancer DOID:0050686 164 0.021
hematopoietic system disease DOID:74 100 0.012
microcephaly DOID:10907 6 0.010
seckel syndrome DOID:0050569 5 0.001