|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
1.000
|
|
|
|
regulation of guanylate cyclase activity
|
GO:0031282 |
2 |
1.000
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
1.000
|
|
|
|
negative regulation of cgmp metabolic process
|
GO:0030824 |
1 |
1.000
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
1.000
|
|
|
|
amino acid betaine transport
|
GO:0015838 |
4 |
1.000
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
1.000
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
1.000
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
1.000
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
1.000
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
1.000
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
1.000
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
1.000
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
1.000
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.999
|
|
|
|
renal absorption
|
GO:0070293 |
6 |
0.999
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.999
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.999
|
|
|
|
microvillus organization
|
GO:0032528 |
2 |
0.999
|
|
|
|
microvillus assembly
|
GO:0030033 |
2 |
0.999
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.999
|
|
|
|
regulation of cgmp biosynthetic process
|
GO:0030826 |
4 |
0.999
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.999
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.998
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.998
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
40 |
0.998
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.998
|
|
|
|
modified amino acid transport
|
GO:0072337 |
11 |
0.998
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.997
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.996
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.996
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.996
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.995
|
|
|
|
negative regulation of lyase activity
|
GO:0051350 |
7 |
0.995
|
|
|
|
negative regulation of nucleotide biosynthetic process
|
GO:0030809 |
11 |
0.994
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.994
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.993
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.992
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.992
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.991
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.989
|
|
|
|
renal system process
|
GO:0003014 |
25 |
0.989
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.989
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.989
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
292 |
0.988
|
|
|
|
inorganic anion transmembrane transport
|
GO:0098661 |
47 |
0.986
|
|
|
|
negative regulation of cyclic nucleotide biosynthetic process
|
GO:0030803 |
10 |
0.986
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.983
|
|
|
|
cgmp metabolic process
|
GO:0046068 |
19 |
0.981
|
|
|
|
regulation of anion transport
|
GO:0044070 |
25 |
0.981
|
|
|
|
negative regulation of cyclase activity
|
GO:0031280 |
6 |
0.980
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.979
|
Rat |
|
|
organic anion transport
|
GO:0015711 |
103 |
0.978
|
Mouse Rat |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.976
|
|
|
|
chloride transport
|
GO:0006821 |
41 |
0.973
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.973
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.972
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.971
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.970
|
|
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
23 |
0.964
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.960
|
|
|
|
regulation of cgmp metabolic process
|
GO:0030823 |
9 |
0.960
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.959
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.957
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.957
|
|
|
|
cgmp biosynthetic process
|
GO:0006182 |
12 |
0.954
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.952
|
|
|
|
system process
|
GO:0003008 |
349 |
0.949
|
Rat |
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.937
|
Mouse |
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.934
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.929
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.917
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
37 |
0.916
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.912
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.912
|
|
|
|
negative regulation of peptidyl cysteine s nitrosylation
|
GO:1902083 |
1 |
0.911
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.905
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.902
|
|
|
|
positive regulation of protein targeting to membrane
|
GO:0090314 |
8 |
0.900
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.900
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.899
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.893
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.891
|
Rat |
|
|
sensory perception
|
GO:0007600 |
103 |
0.880
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.877
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.866
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.865
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.864
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.854
|
|
|
|
regulation of peptidyl cysteine s nitrosylation
|
GO:2000169 |
1 |
0.854
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.853
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.851
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.842
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
76 |
0.840
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.832
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.832
|
|
|
|
protein nitrosylation
|
GO:0017014 |
1 |
0.826
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.823
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.819
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.817
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.815
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.811
|
|
|
|
negative regulation of leukocyte degranulation
|
GO:0043301 |
1 |
0.797
|
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.794
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.786
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.784
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.784
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.775
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.775
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.774
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.769
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.764
|
|
|
|
regulation of excretion
|
GO:0044062 |
1 |
0.762
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.761
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.758
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.746
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.745
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
29 |
0.739
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
32 |
0.733
|
|
|
|
negative regulation of cyclic nucleotide metabolic process
|
GO:0030800 |
10 |
0.728
|
|
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
2 |
0.722
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.717
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.710
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.708
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.703
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.697
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.697
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.691
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.691
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.690
|
Mouse |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.673
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.669
|
Mouse Rat |
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.655
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.651
|
Mouse |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.643
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.638
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.635
|
|
|
|
detection of chemical stimulus involved in sensory perception of sweet taste
|
GO:0001582 |
2 |
0.631
|
|
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
0.628
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.626
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.624
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.624
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.621
|
Mouse |
|
|
negative regulation of purine nucleotide biosynthetic process
|
GO:1900372 |
11 |
0.620
|
|
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.618
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.617
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.612
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.606
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.606
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.604
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.602
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.599
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.591
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.588
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.587
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.584
|
Rat |
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.582
|
|
|
|
regulation of actin filament based movement
|
GO:1903115 |
24 |
0.576
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.565
|
|
|
|
negative regulation of regulated secretory pathway
|
GO:1903306 |
1 |
0.560
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.560
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.558
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.546
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.527
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.527
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.520
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.519
|
|
|
|
regulation of ventricular cardiac muscle cell membrane repolarization
|
GO:0060307 |
10 |
0.512
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.493
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.491
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.490
|
|
|
|
inner ear development
|
GO:0048839 |
8 |
0.487
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.482
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.477
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
3 |
0.471
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.469
|
|
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
28 |
0.465
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.464
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.462
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.461
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.455
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.454
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.454
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.453
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.449
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
26 |
0.447
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.443
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.441
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.428
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.426
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.421
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.417
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.415
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.413
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.411
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.408
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.404
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.396
|
|
|
|
quaternary ammonium group transport
|
GO:0015697 |
5 |
0.395
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.386
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.385
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.383
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.377
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.365
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.363
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.354
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.352
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.349
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.346
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.345
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.345
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.342
|
|
|
|
peptidyl cysteine s nitrosylation
|
GO:0018119 |
1 |
0.312
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.311
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.310
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.308
|
Zebrafish |
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.306
|
|
|
|
carnitine transport
|
GO:0015879 |
4 |
0.306
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.305
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.301
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.293
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.293
|
|
|
|
ear development
|
GO:0043583 |
14 |
0.292
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.291
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.287
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.285
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.280
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.278
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.278
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.277
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.277
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.275
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.271
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.269
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.268
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.268
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.267
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.259
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.254
|
|
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
15 |
0.248
|
|
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.247
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.240
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.240
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.239
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.238
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.234
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
11 |
0.231
|
|
|
|
inorganic anion transport
|
GO:0015698 |
60 |
0.230
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.227
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.220
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.219
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.217
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.217
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.216
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.215
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.214
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.210
|
|
|
|
head development
|
GO:0060322 |
108 |
0.208
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.205
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.204
|
|
|
|
positive regulation of membrane potential
|
GO:0045838 |
2 |
0.203
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.203
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.202
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.201
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.200
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.200
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.198
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.194
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.193
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.190
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.189
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.186
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.182
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.177
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.176
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.173
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.172
|
|
|
|
cardiac muscle cell cardiac muscle cell adhesion
|
GO:0086042 |
1 |
0.172
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.171
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.171
|
Rat |
|
|
phosphate ion homeostasis
|
GO:0055062 |
7 |
0.169
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.167
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.166
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.166
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.165
|
Mouse |
|
|
heart process
|
GO:0003015 |
62 |
0.163
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.162
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.161
|
Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.159
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.158
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.156
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.156
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.154
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.154
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.153
|
Zebrafish |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.153
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.151
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.150
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.149
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.148
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.148
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.147
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.146
|
Zebrafish |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.145
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.142
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.142
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.141
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.141
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.140
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.139
|
Mouse Rat |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.138
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.138
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.137
|
Mouse |
|
|
mesendoderm development
|
GO:0048382 |
1 |
0.137
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.137
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.134
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.132
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.131
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.130
|
Rat |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.129
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.128
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.127
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.127
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.122
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.122
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.122
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.121
|
|
|
|
presynaptic membrane organization
|
GO:0097090 |
3 |
0.121
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.120
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.120
|
|
|
|
positive regulation of phosphatidylinositol biosynthetic process
|
GO:0010513 |
3 |
0.119
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.118
|
|
|
|
negative regulation of catagen
|
GO:0051796 |
1 |
0.118
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.114
|
|
|
|
neutrophil degranulation
|
GO:0043312 |
3 |
0.113
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.112
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.112
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.111
|
Mouse Rat |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.111
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.111
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.110
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.110
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.110
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.109
|
|
|
|
regulation of atpase activity
|
GO:0043462 |
25 |
0.108
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
10 |
0.107
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.107
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.106
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.106
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.105
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.103
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.102
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.101
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.100
|
|
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.099
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.099
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.099
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.099
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.098
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.096
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.095
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.094
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.093
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.093
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.093
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.093
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
4 |
0.093
|
|
|
|
positive regulation of keratinocyte proliferation
|
GO:0010838 |
4 |
0.093
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.092
|
Zebrafish |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.089
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.089
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.089
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.089
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
22 |
0.089
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.088
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.088
|
|
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.088
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.086
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.085
|
Zebrafish |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.084
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.084
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.084
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.083
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.083
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.083
|
|
|
|
mating
|
GO:0007618 |
1 |
0.082
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.082
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.081
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.081
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.079
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.077
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.077
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.077
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.076
|
|
|
|
cellular trivalent inorganic anion homeostasis
|
GO:0072502 |
4 |
0.076
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.076
|
|
|
|
response to sucrose
|
GO:0009744 |
1 |
0.075
|
|
|
|
chloride transmembrane transport
|
GO:1902476 |
38 |
0.074
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.074
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.072
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.071
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.071
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.071
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.070
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.069
|
|
|
|
trivalent inorganic anion homeostasis
|
GO:0072506 |
7 |
0.068
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.068
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.068
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.068
|
|
|
|
positive regulation of atpase activity
|
GO:0032781 |
19 |
0.067
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.067
|
Mouse Rat |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.065
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.065
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.065
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.065
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.065
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.065
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.065
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.064
|
|
|
|
signal transduction involved in regulation of gene expression
|
GO:0023019 |
1 |
0.064
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.064
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.064
|
|
|
|
detection of chemical stimulus
|
GO:0009593 |
55 |
0.064
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.064
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.063
|
|
|
|
adenylate cyclase inhibiting adrenergic receptor signaling pathway
|
GO:0071881 |
1 |
0.063
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.063
|
Mouse |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.063
|
|
|
|
amino acid transport
|
GO:0006865 |
28 |
0.062
|
|
|
|
negative regulation of neutrophil activation
|
GO:1902564 |
1 |
0.061
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.061
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.061
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.061
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.060
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
7 |
0.060
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.060
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
42 |
0.059
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.059
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.058
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.058
|
|
|
|
retina homeostasis
|
GO:0001895 |
42 |
0.058
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.058
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.058
|
|
|
|
regulation of sodium proton antiporter activity
|
GO:0032415 |
3 |
0.057
|
|
|
|
memory
|
GO:0007613 |
3 |
0.056
|
|
|
|
regulation of melanin biosynthetic process
|
GO:0048021 |
1 |
0.056
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.056
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.056
|
|
|
|
positive regulation of transporter activity
|
GO:0032411 |
32 |
0.056
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.055
|
Zebrafish |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.055
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.055
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.054
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.054
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.054
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.054
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.053
|
|
|
|
activation of mapk activity by adrenergic receptor signaling pathway
|
GO:0071883 |
3 |
0.053
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.053
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.053
|
Mouse |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.053
|
Mouse |
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.052
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.052
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.052
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.052
|
|
|
|
regulation of melanosome transport
|
GO:1902908 |
1 |
0.052
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.051
|
Mouse Rat |
|
|
immune effector process
|
GO:0002252 |
159 |
0.051
|
Zebrafish |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.050
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.050
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.050
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.049
|
|
|
|
peptidyl cysteine modification
|
GO:0018198 |
9 |
0.049
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.048
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.048
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.048
|
|
|
|
aging
|
GO:0007568 |
66 |
0.048
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.048
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.047
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.047
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.046
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.046
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.046
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.046
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.046
|
Rat |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.046
|
|
|
|
response to low density lipoprotein particle
|
GO:0055098 |
4 |
0.046
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.046
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.045
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.045
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.045
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.045
|
|
