Homo sapiens

39 known processes

CHAF1B

chromatin assembly factor 1, subunit B (p60)

(Aliases: CAF1A,CAF-IP60,MPP7,MPHOSPH7,CAF1,CAF-1,CAF1P60)

CHAF1B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication dependent nucleosome assembly GO:0006335 32 0.970
dna replication dependent nucleosome organization GO:0034723 32 0.920
chromatin assembly or disassembly GO:0006333 78 0.898
chromatin assembly GO:0031497 61 0.864
protein dna complex assembly GO:0065004 64 0.835
dna replication independent nucleosome assembly GO:0006336 27 0.812
dna conformation change GO:0071103 113 0.812
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.746
nucleosome assembly GO:0006334 50 0.715
histone acetylation GO:0016573 93 0.693
chromatin organization GO:0006325 351 0.604
nucleosome organization GO:0034728 66 0.570
dna replication GO:0006260 116 0.504
mitotic sister chromatid segregation GO:0000070 53 0.488
dna dependent dna replication GO:0006261 44 0.485
oogenesis GO:0048477 2 0.472
mitotic cell cycle phase transition GO:0044772 162 0.391
cellular ketone metabolic process GO:0042180 80 0.387
dna packaging GO:0006323 77 0.372
female gamete generation GO:0007292 2 0.369
regulation of cellular amine metabolic process GO:0033238 11 0.313
dna repair GO:0006281 198 0.307
protein modification by small protein conjugation GO:0032446 342 0.267
cellular amine metabolic process GO:0044106 41 0.257
covalent chromatin modification GO:0016569 254 0.249
histone exchange GO:0043486 3 0.247
cell development GO:0048468 328 0.245
regulation of cellular ketone metabolic process GO:0010565 50 0.236
protein dna complex subunit organization GO:0071824 80 0.217
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.215
chromatin modification GO:0016568 298 0.211
internal protein amino acid acetylation GO:0006475 101 0.194
sister chromatid segregation GO:0000819 54 0.194
dna replication independent nucleosome organization GO:0034724 27 0.186
cellular amino acid metabolic process GO:0006520 116 0.181
histone modification GO:0016570 251 0.180
double strand break repair GO:0006302 101 0.174
heterochromatin organization GO:0070828 6 0.169
cellular macromolecular complex assembly GO:0034622 324 0.158
regulation of chromosome segregation GO:0051983 44 0.155
protein catabolic process GO:0030163 325 0.151
positive regulation of cellular amine metabolic process GO:0033240 7 0.150
post embryonic development GO:0009791 2 0.146
mitotic cell cycle process GO:1903047 286 0.133
internal peptidyl lysine acetylation GO:0018393 97 0.128
protein acetylation GO:0006473 116 0.125
single organism reproductive process GO:0044702 98 0.118
regulation of chromatin organization GO:1902275 56 0.114
nucleosome disassembly GO:0006337 12 0.112
nuclear division GO:0000280 128 0.107
regulation of chromatin modification GO:1903308 51 0.106
positive regulation of organelle organization GO:0010638 195 0.106
reproductive process GO:0022414 106 0.101
regulation of cellular amino acid metabolic process GO:0006521 6 0.100
modification dependent protein catabolic process GO:0019941 209 0.100
cellular protein catabolic process GO:0044257 261 0.100
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.097
recombinational repair GO:0000725 50 0.096
nucleoside triphosphate catabolic process GO:0009143 394 0.094
double strand break repair via homologous recombination GO:0000724 50 0.094
amine metabolic process GO:0009308 44 0.093
negative regulation of mitotic cell cycle GO:0045930 102 0.091
cell projection organization GO:0030030 252 0.089
histone ubiquitination GO:0016574 31 0.086
determination of adult lifespan GO:0008340 2 0.079
positive regulation of histone modification GO:0031058 29 0.077
behavior GO:0007610 112 0.076
cellular response to dna damage stimulus GO:0006974 379 0.075
purine nucleoside triphosphate catabolic process GO:0009146 392 0.075
nucleoside monophosphate metabolic process GO:0009123 191 0.073
protein ubiquitination GO:0016567 314 0.069
ubiquitin dependent protein catabolic process GO:0006511 206 0.067
purine ribonucleotide catabolic process GO:0009154 404 0.066
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.065
mitotic cell cycle GO:0000278 326 0.062
Zebrafish
ras protein signal transduction GO:0007265 73 0.062
chromatin remodeling GO:0006338 55 0.062
organophosphate catabolic process GO:0046434 430 0.060
embryo development GO:0009790 123 0.060
Zebrafish
regulation of cell cycle GO:0051726 393 0.060
regulation of gene silencing GO:0060968 24 0.058
mitotic cell cycle checkpoint GO:0007093 68 0.057
negative regulation of cell cycle process GO:0010948 121 0.057
lagging strand elongation GO:0006273 3 0.057
neuron differentiation GO:0030182 138 0.057
purine ribonucleoside metabolic process GO:0046128 437 0.057
regulation of mitotic cell cycle GO:0007346 189 0.054
nervous system development GO:0007399 293 0.053
base excision repair GO:0006284 21 0.052
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.051
cell cycle phase transition GO:0044770 173 0.050
negative regulation of cell cycle phase transition GO:1901988 89 0.050
dna biosynthetic process GO:0071897 40 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.050
atp metabolic process GO:0046034 176 0.049
cellular component morphogenesis GO:0032989 314 0.049
ribonucleoside monophosphate metabolic process GO:0009161 187 0.048
ribonucleotide catabolic process GO:0009261 405 0.048
developmental process involved in reproduction GO:0003006 66 0.047
chromatin silencing GO:0006342 12 0.047
positive regulation of histone h3 k9 methylation GO:0051574 3 0.047
mrna processing GO:0006397 133 0.044
positive regulation of chromatin modification GO:1903310 30 0.044
mitotic nuclear division GO:0007067 119 0.044
protein maturation GO:0051604 233 0.044
gene silencing GO:0016458 49 0.044
regulation of chromosome organization GO:0033044 103 0.044
mitotic sister chromatid separation GO:0051306 18 0.043
reproductive structure development GO:0048608 55 0.042
negative regulation of gene expression epigenetic GO:0045814 19 0.042
nucleoside phosphate catabolic process GO:1901292 412 0.041
chromosome segregation GO:0007059 114 0.041
histone h2b ubiquitination GO:0033523 8 0.041
mitotic sister chromatid cohesion GO:0007064 12 0.040
regulation of proteasomal protein catabolic process GO:0061136 87 0.040
neurogenesis GO:0022008 169 0.039
organophosphate biosynthetic process GO:0090407 163 0.039
rna processing GO:0006396 255 0.039
neuron projection development GO:0031175 106 0.039
proteasomal protein catabolic process GO:0010498 176 0.038
centrosome organization GO:0051297 58 0.038
regulation of mitosis GO:0007088 63 0.038
protein alkylation GO:0008213 74 0.037
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.037
purine containing compound catabolic process GO:0072523 411 0.037
macromolecular complex disassembly GO:0032984 60 0.037
purine nucleoside catabolic process GO:0006152 398 0.037
cell morphogenesis GO:0000902 296 0.036
protein processing GO:0016485 226 0.036
nucleoside monophosphate catabolic process GO:0009125 159 0.036
peptidyl lysine dimethylation GO:0018027 3 0.036
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.035
purine nucleotide catabolic process GO:0006195 405 0.035
modification dependent macromolecule catabolic process GO:0043632 212 0.035
multicellular organismal aging GO:0010259 3 0.035
regulation of cell cycle phase transition GO:1901987 126 0.035
atp dependent chromatin remodeling GO:0043044 25 0.035
dna synthesis involved in dna repair GO:0000731 6 0.034
male meiosis GO:0007140 1 0.034
regulation of protein maturation GO:1903317 150 0.034
positive regulation of cellular component organization GO:0051130 376 0.034
intracellular protein transport GO:0006886 270 0.034
reproduction GO:0000003 63 0.033
cell cycle g1 s phase transition GO:0044843 80 0.033
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.033
protein acylation GO:0043543 138 0.033
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.033
regulation of dna templated transcription elongation GO:0032784 23 0.033
g1 s transition of mitotic cell cycle GO:0000082 78 0.032
dna recombination GO:0006310 77 0.032
positive regulation of dna templated transcription elongation GO:0032786 18 0.031
atp catabolic process GO:0006200 157 0.031
response to external biotic stimulus GO:0043207 261 0.030
multi organism reproductive process GO:0044703 54 0.030
protein complex disassembly GO:0043241 52 0.030
regulation of growth GO:0040008 165 0.030
dna templated transcription elongation GO:0006354 25 0.029
deoxyribonucleotide metabolic process GO:0009262 6 0.029
cell projection morphogenesis GO:0048858 129 0.029
cell growth GO:0016049 160 0.029
positive regulation of cell proliferation GO:0008284 301 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.029
cell part morphogenesis GO:0032990 137 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
gene conversion GO:0035822 1 0.028
positive regulation of dna metabolic process GO:0051054 73 0.028
response to abiotic stimulus GO:0009628 336 0.028
ribonucleoside catabolic process GO:0042454 406 0.027
sister chromatid cohesion GO:0007062 24 0.026
regulation of cell growth GO:0001558 135 0.026
telomere maintenance GO:0000723 32 0.026
positive regulation of hydrolase activity GO:0051345 331 0.025
glycosyl compound catabolic process GO:1901658 413 0.025
cellular component disassembly GO:0022411 92 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.025
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.025
muscle organ development GO:0007517 56 0.025
peptidyl lysine acetylation GO:0018394 101 0.025
regulation of transcription by chromatin organization GO:0034401 1 0.024
regulation of histone modification GO:0031056 47 0.024
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.024
regulation of protein processing GO:0070613 150 0.024
positive regulation of nuclease activity GO:0032075 5 0.024
regulation of mitotic sister chromatid segregation GO:0033047 27 0.024
peptidyl lysine modification GO:0018205 144 0.023
regulation of histone acetylation GO:0035065 19 0.023
mitotic dna integrity checkpoint GO:0044774 30 0.023
immune response GO:0006955 307 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
positive regulation of chromosome organization GO:2001252 41 0.023
regeneration GO:0031099 4 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
rna splicing via transesterification reactions GO:0000375 90 0.022
nucleoside catabolic process GO:0009164 408 0.022
single organism cellular localization GO:1902580 332 0.021
regulation of mrna metabolic process GO:1903311 53 0.021
regulation of mitotic cell cycle phase transition GO:1901990 118 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
neuron development GO:0048666 113 0.021
carbohydrate derivative biosynthetic process GO:1901137 207 0.021
regulation of cell cycle process GO:0010564 266 0.021
protein oligomerization GO:0051259 173 0.020
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.020
mrna splicing via spliceosome GO:0000398 89 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
macromolecule methylation GO:0043414 97 0.020
sex determination GO:0007530 3 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
negative regulation of proteolysis GO:0045861 132 0.019
cell cycle g2 m phase transition GO:0044839 43 0.019
negative regulation of protein maturation GO:1903318 142 0.019
cell morphogenesis involved in differentiation GO:0000904 144 0.019
regulation of dna replication GO:0006275 68 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
dna replication initiation GO:0006270 6 0.018
metaphase anaphase transition of cell cycle GO:0044784 21 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
growth GO:0040007 202 0.017
regulation of dna templated transcription in response to stress GO:0043620 18 0.017
negative regulation of cell death GO:0060548 345 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
negative regulation of organelle organization GO:0010639 126 0.017
regulation of protein catabolic process GO:0042176 155 0.017
regulation of intracellular transport GO:0032386 195 0.017
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
regulation of dna metabolic process GO:0051052 153 0.016
blastocyst development GO:0001824 3 0.016
response to ionizing radiation GO:0010212 65 0.016
mrna metabolic process GO:0016071 175 0.016
regulation of mitotic sister chromatid separation GO:0010965 27 0.016
regulation of proteolysis GO:0030162 293 0.016
circulatory system development GO:0072359 262 0.016
dephosphorylation GO:0016311 209 0.016
endomembrane system organization GO:0010256 196 0.015
negative regulation of catabolic process GO:0009895 104 0.015
vesicle mediated transport GO:0016192 371 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
negative regulation of sister chromatid segregation GO:0033046 17 0.015
response to fungus GO:0009620 4 0.015
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.015
myosin filament assembly GO:0031034 2 0.015
positive regulation of heterochromatin assembly GO:0031453 1 0.015
g2 m transition of mitotic cell cycle GO:0000086 41 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
cytokinesis GO:0000910 96 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
negative regulation of notch signaling pathway GO:0045746 10 0.014
chromosome separation GO:0051304 23 0.014
regulation of protein acetylation GO:1901983 25 0.014
heterochromatin assembly GO:0031507 6 0.014
positive regulation of mitotic cell cycle GO:0045931 60 0.014
regulation of gene expression epigenetic GO:0040029 73 0.014
embryo development ending in birth or egg hatching GO:0009792 34 0.014
protein targeting GO:0006605 187 0.014
spermatid development GO:0007286 4 0.014
biological adhesion GO:0022610 331 0.013
sex differentiation GO:0007548 45 0.013
2 deoxyribonucleotide metabolic process GO:0009394 6 0.013
generation of neurons GO:0048699 152 0.013
multicellular organism reproduction GO:0032504 42 0.013
purine nucleoside monophosphate catabolic process GO:0009128 158 0.013
response to oxygen containing compound GO:1901700 369 0.013
regulation of cell cycle g1 s phase transition GO:1902806 42 0.013
protein localization to organelle GO:0033365 280 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
response to biotic stimulus GO:0009607 276 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
negative regulation of cell division GO:0051782 31 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.012
cell projection assembly GO:0030031 126 0.012
negative regulation of cell cycle GO:0045786 193 0.012
notch signaling pathway GO:0007219 31 0.012
Fly
anatomical structure homeostasis GO:0060249 100 0.012
negative regulation of cellular protein metabolic process GO:0032269 353 0.012
response to uv GO:0009411 73 0.012
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
protein dna complex disassembly GO:0032986 12 0.012
endocytosis GO:0006897 159 0.012
meiosis i GO:0007127 4 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.012
cell division GO:0051301 168 0.012
positive regulation of cell cycle GO:0045787 140 0.012
regulation of kinase activity GO:0043549 314 0.012
positive regulation of developmental process GO:0051094 314 0.012
cell cell signaling GO:0007267 155 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
dna hypermethylation GO:0044026 1 0.012
organelle fission GO:0048285 149 0.012
neuron projection morphogenesis GO:0048812 50 0.012
methylation GO:0032259 106 0.012
gonad development GO:0008406 34 0.012
dendrite development GO:0016358 24 0.012
negative regulation of protein processing GO:0010955 142 0.012
actin filament based process GO:0030029 224 0.012
rna splicing GO:0008380 131 0.011
negative regulation of dna metabolic process GO:0051053 57 0.011
response to radiation GO:0009314 151 0.011
ribonucleoside monophosphate catabolic process GO:0009158 158 0.011
cell activation GO:0001775 213 0.011
humoral immune response GO:0006959 49 0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.011
microtubule based process GO:0007017 210 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
histone lysine methylation GO:0034968 50 0.011
apoptotic signaling pathway GO:0097190 268 0.011
regulation of chromatin silencing GO:0031935 8 0.011
multicellular organismal reproductive process GO:0048609 40 0.011
muscle structure development GO:0061061 98 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.011
positive regulation of cytoplasmic transport GO:1903651 82 0.011
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
cytoplasmic transport GO:0016482 379 0.010
response to other organism GO:0051707 261 0.010
cell fate determination GO:0001709 3 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
cell type specific apoptotic process GO:0097285 125 0.010
regulation of peptidyl lysine acetylation GO:2000756 22 0.010
dna catabolic process GO:0006308 49 0.010
cellular lipid metabolic process GO:0044255 303 0.010
dna integrity checkpoint GO:0031570 71 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010
cofactor metabolic process GO:0051186 87 0.010
regulation of rna splicing GO:0043484 62 0.010
response to growth factor GO:0070848 205 0.010
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.010

CHAF1B disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.217
hematopoietic system disease DOID:74 100 0.217
disease of cellular proliferation DOID:14566 174 0.019
cancer DOID:162 167 0.018
organ system cancer DOID:0050686 164 0.018
bone development disease DOID:0080006 55 0.011
bone disease DOID:0080001 88 0.011
musculoskeletal system disease DOID:17 223 0.011
connective tissue disease DOID:65 109 0.011
disease of metabolism DOID:0014667 295 0.010