|
|
cyclin catabolic process
|
GO:0008054 |
6 |
0.993
|
Fly |
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.972
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.968
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.940
|
Fly |
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.922
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.913
|
Fly |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.911
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.842
|
Fly |
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.828
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.822
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.788
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.775
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.761
|
Worm |
|
|
spindle stabilization
|
GO:0043146 |
4 |
0.754
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.736
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.730
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.728
|
Fly |
|
|
regulation of triglyceride catabolic process
|
GO:0010896 |
6 |
0.715
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.695
|
Worm |
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.693
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.690
|
|
|
|
positive regulation of attachment of spindle microtubules to kinetochore
|
GO:0051987 |
2 |
0.668
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.655
|
Fly |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.637
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.632
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.598
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.597
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.596
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.592
|
Fly |
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.581
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.577
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.572
|
|
|
|
regulation of attachment of spindle microtubules to kinetochore
|
GO:0051988 |
9 |
0.554
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.523
|
|
|
|
cellular response to iron ion
|
GO:0071281 |
1 |
0.510
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.502
|
|
|
|
mitotic spindle stabilization
|
GO:0043148 |
2 |
0.490
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.486
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.440
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.436
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
0.427
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.417
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.394
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.386
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.384
|
Fly |
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.384
|
|
|
|
ventricular cardiac muscle cell differentiation
|
GO:0055012 |
1 |
0.361
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.358
|
|
|
|
regulation of mitotic spindle organization
|
GO:0060236 |
6 |
0.349
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.333
|
Worm |
|
|
microtubule depolymerization
|
GO:0007019 |
18 |
0.300
|
|
|
|
neutral lipid catabolic process
|
GO:0046461 |
12 |
0.299
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.294
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.293
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.286
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.283
|
Fly |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.282
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.280
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.278
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.277
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.276
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.268
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.260
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.260
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.249
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.242
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.242
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.240
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.240
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.234
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.230
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.229
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.226
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.217
|
Worm |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.216
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.215
|
Fly |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.215
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.212
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.210
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.209
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.197
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.196
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.196
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.193
|
|
|
|
deoxyribose phosphate metabolic process
|
GO:0019692 |
6 |
0.190
|
|
|
|
regulation of spindle organization
|
GO:0090224 |
10 |
0.190
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.186
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.181
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.179
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.177
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.170
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.167
|
Worm Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.167
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.167
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.165
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.165
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.164
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.160
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.158
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.156
|
Fly |
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.154
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.150
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.148
|
|
|
|
cellular response to fatty acid
|
GO:0071398 |
8 |
0.144
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.141
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.136
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.134
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.129
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.127
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.127
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.124
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.123
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.121
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.117
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.115
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.114
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.113
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.112
|
|
|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
0.110
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.107
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.107
|
|
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.106
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.104
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.104
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.104
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.101
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.101
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.100
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.100
|
|
|
|
negative regulation of meiotic cell cycle
|
GO:0051447 |
2 |
0.099
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.099
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.098
|
Worm Fly |
|
|
organelle localization
|
GO:0051640 |
84 |
0.097
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.095
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.094
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.094
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.094
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.093
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.088
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.088
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.087
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.085
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.083
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.081
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.080
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.075
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.075
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.075
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.075
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.075
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.075
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.073
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.071
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.070
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.070
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
6 |
0.069
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.067
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.067
|
|
|
|
protein k11 linked ubiquitination
|
GO:0070979 |
24 |
0.066
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.065
|
Worm Fly |
|
|
positive regulation of nuclear cell cycle dna replication
|
GO:0010571 |
4 |
0.064
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.064
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.062
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.062
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.061
|
|
|
|
7 methylguanosine mrna capping
|
GO:0006370 |
7 |
0.061
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.061
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.058
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.057
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.056
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.054
|
|
|
|
phosphorylation of rna polymerase ii c terminal domain
|
GO:0070816 |
3 |
0.053
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.053
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.052
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.052
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.052
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.051
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.051
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.050
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.050
|
|
|
|
negative regulation of mitotic sister chromatid separation
|
GO:2000816 |
17 |
0.050
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.049
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.049
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.049
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.048
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.048
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
24 |
0.048
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.048
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.047
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.047
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.047
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.047
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.046
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.046
|
|
|
|
acylglycerol catabolic process
|
GO:0046464 |
12 |
0.044
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.044
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.044
|
|
|
|
growth
|
GO:0040007 |
202 |
0.043
|
|
|
|
negative regulation of sister chromatid segregation
|
GO:0033046 |
17 |
0.043
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.043
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.043
|
|
|
|
negative regulation of chromosome segregation
|
GO:0051985 |
18 |
0.042
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.042
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.042
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.041
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.041
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.040
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.040
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.040
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.039
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.039
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.039
|
Fly |
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.038
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.038
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.038
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.037
|
|
|
|
positive regulation of mrna processing
|
GO:0050685 |
17 |
0.037
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.036
|
Worm Fly |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.036
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.035
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.035
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.034
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.034
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.034
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.033
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.033
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
17 |
0.033
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.033
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.032
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.032
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.032
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.031
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.031
|
|
|
|
2 deoxyribonucleotide metabolic process
|
GO:0009394 |
6 |
0.031
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.031
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.030
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.030
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.029
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.029
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.029
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.029
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.029
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.029
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.028
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.028
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.026
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.026
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.026
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.026
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.026
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.025
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.025
|
Fly |
|
|
centrosome organization
|
GO:0051297 |
58 |
0.025
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.025
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.025
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.025
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.025
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.024
|
|
|
|
microtubule polymerization
|
GO:0046785 |
18 |
0.024
|
|
|
|
regulation of protein polyubiquitination
|
GO:1902914 |
8 |
0.024
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.023
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.023
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.023
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.023
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
22 |
0.023
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.023
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.022
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.022
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.022
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.022
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.022
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.022
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.021
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.021
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.021
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.021
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.021
|
Worm |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.021
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.021
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.020
|
|
|
|
mitotic metaphase plate congression
|
GO:0007080 |
14 |
0.020
|
|
|
|
deoxyribonucleotide metabolic process
|
GO:0009262 |
6 |
0.020
|
|
|
|
fertilization
|
GO:0009566 |
12 |
0.020
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.020
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.019
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.019
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.019
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.019
|
Worm |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.019
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.019
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.019
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.019
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.019
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.019
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.019
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.019
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.019
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.019
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.018
|
|
|
|
system process
|
GO:0003008 |
349 |
0.018
|
|
|
|
negative regulation of metaphase anaphase transition of cell cycle
|
GO:1902100 |
17 |
0.018
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
18 |
0.018
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.018
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
7 |
0.018
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.018
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.018
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.018
|
Worm Fly |
|
|
gland development
|
GO:0048732 |
48 |
0.018
|
|
|
|
regulation of chromatin binding
|
GO:0035561 |
3 |
0.017
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
53 |
0.017
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.017
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.017
|
|
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.017
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.017
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.017
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.017
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.017
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.017
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.017
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.017
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.016
|
|
|
|
aging
|
GO:0007568 |
66 |
0.016
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.016
|
|
|
|
nucleoside biosynthetic process
|
GO:0009163 |
26 |
0.016
|
|
|
|
positive regulation of heart growth
|
GO:0060421 |
2 |
0.016
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.016
|
|
|
|
rna phosphodiester bond hydrolysis
|
GO:0090501 |
35 |
0.016
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.016
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.016
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.016
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.015
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
20 |
0.015
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.015
|
|
|
|
ribosomal small subunit export from nucleus
|
GO:0000056 |
3 |
0.015
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.015
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.015
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.015
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.015
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.015
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.015
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.015
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.015
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.015
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.015
|
|
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.015
|
|
|
|
urate metabolic process
|
GO:0046415 |
11 |
0.014
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.014
|
Worm Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.014
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.014
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.014
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.014
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.014
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.014
|
|
|
|
positive regulation of protein polyubiquitination
|
GO:1902916 |
3 |
0.014
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.013
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.013
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.013
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.013
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.013
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.013
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.013
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.013
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.013
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.013
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.013
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
8 |
0.013
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.013
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.013
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.013
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.013
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.013
|
|
|
|
regulation of g0 to g1 transition
|
GO:0070316 |
2 |
0.013
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.012
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.012
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.012
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.012
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.012
|
|
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
15 |
0.012
|
|
|
|
spindle checkpoint
|
GO:0031577 |
26 |
0.012
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.012
|
|
|
|
positive regulation of cardiac muscle tissue growth
|
GO:0055023 |
2 |
0.012
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.012
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.012
|
|
|
|
metaphase plate congression
|
GO:0051310 |
18 |
0.012
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.012
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.012
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.012
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.012
|
|
|
|
positive regulation of mrna 3 end processing
|
GO:0031442 |
12 |
0.012
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.012
|
|
|
|
negative regulation of cell division
|
GO:0051782 |
31 |
0.012
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.012
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.011
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.011
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.011
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.011
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.011
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.011
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.011
|
|
|
|
dna synthesis involved in dna repair
|
GO:0000731 |
6 |
0.011
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.011
|
|
|
|
negative regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032435 |
30 |
0.011
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.011
|
Worm Fly |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.011
|
|
|
|
chromosome localization
|
GO:0050000 |
20 |
0.011
|
|
|
|
negative regulation of mitotic sister chromatid segregation
|
GO:0033048 |
17 |
0.011
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.011
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.011
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.011
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
19 |
0.011
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.011
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.010
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.010
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.010
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.010
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.010
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.010
|
|
|
|
regulation of sister chromatid cohesion
|
GO:0007063 |
9 |
0.010
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.010
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.010
|
|
