|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.783
|
|
|
|
photoreceptor cell maintenance
|
GO:0045494 |
13 |
0.728
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.534
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.415
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.317
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.316
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.307
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.304
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.275
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.249
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.245
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.244
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.240
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.228
|
Mouse |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.222
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.210
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.204
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.204
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.202
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.198
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.191
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.191
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.188
|
Mouse |
|
|
centrosome separation
|
GO:0051299 |
3 |
0.184
|
|
|
|
vesicle transport along microtubule
|
GO:0047496 |
4 |
0.184
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.178
|
|
|
|
mitotic centrosome separation
|
GO:0007100 |
1 |
0.178
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.176
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.171
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.171
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.169
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.167
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.163
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.161
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.157
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.156
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.153
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.148
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.139
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.139
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.139
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.138
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.135
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.134
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.132
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.132
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.132
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.131
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.131
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.130
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.128
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.127
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.126
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.124
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.123
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.123
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.120
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.116
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.116
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.115
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.114
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.113
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.113
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.113
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.113
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.113
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.110
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.110
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.109
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.107
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.106
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.104
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.103
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.098
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.095
|
|
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
1 |
0.095
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.094
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.094
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
21 |
0.088
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.088
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.087
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.087
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.086
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.085
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.083
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.083
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.082
|
|
|
|
system process
|
GO:0003008 |
349 |
0.082
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.082
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.081
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.080
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.080
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.079
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.077
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.076
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.076
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.076
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.075
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.074
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.073
|
Mouse |
|
|
retrograde axon cargo transport
|
GO:0008090 |
1 |
0.071
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.070
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.070
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.069
|
|
|
|
cerebral cortex neuron differentiation
|
GO:0021895 |
1 |
0.069
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.068
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.068
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.068
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.067
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.067
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.066
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.066
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.065
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.065
|
|
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.065
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.065
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.065
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.064
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.064
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.064
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.063
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.063
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.062
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.061
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.061
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.061
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.061
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.061
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.061
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.061
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.060
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.060
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.060
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.060
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.060
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.059
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.059
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.057
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.057
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.057
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.057
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.057
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.057
|
Mouse |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.055
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
30 |
0.054
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.053
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.053
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.053
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.053
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.053
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.052
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.052
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.052
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.052
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.052
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.051
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.051
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.050
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.050
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.050
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.050
|
|
|
|
muscle cell cellular homeostasis
|
GO:0046716 |
3 |
0.049
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.049
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.049
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.049
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.049
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.049
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.048
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.048
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.048
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.048
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.048
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.048
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.047
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.047
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.047
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.047
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.047
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.046
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.046
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.046
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.046
|
|
|
|
retina homeostasis
|
GO:0001895 |
42 |
0.045
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.045
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.045
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.045
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
5 |
0.044
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.044
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.044
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.044
|
|
|
|
protein localization to kinetochore
|
GO:0034501 |
10 |
0.043
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.043
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.042
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.041
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.041
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.041
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.041
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.041
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.041
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.040
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.040
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.040
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.040
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.040
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.040
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.040
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.039
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.039
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.039
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.039
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.039
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.039
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.038
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.038
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.038
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.038
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.037
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.037
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
3 |
0.037
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.037
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.037
|
|
|
|
head development
|
GO:0060322 |
108 |
0.036
|
|
|
|
growth
|
GO:0040007 |
202 |
0.036
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.036
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.036
|
|
|
|
microtubule polymerization
|
GO:0046785 |
18 |
0.035
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.035
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.035
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.035
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.035
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.035
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.035
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.035
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.034
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.034
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.034
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
4 |
0.033
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.033
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.033
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.033
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.033
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.033
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.033
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.033
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.033
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.032
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.032
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.032
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.032
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.032
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.031
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.031
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.031
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.031
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.031
|
|
|
|
reciprocal meiotic recombination
|
GO:0007131 |
4 |
0.031
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.031
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.031
|
|
|
|
translation
|
GO:0006412 |
132 |
0.030
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.030
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.030
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.030
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.030
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.030
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.030
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.030
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.030
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.030
|
|
|
|
cerebral cortex development
|
GO:0021987 |
10 |
0.030
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.029
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.029
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.029
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.029
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.029
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.029
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.029
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.029
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.029
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.029
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.029
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.028
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.028
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.028
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.028
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.028
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.028
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.028
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.028
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.028
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.028
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.028
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.028
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.028
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.028
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.027
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.027
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.027
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.027
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.027
|
|
|
|
corpus callosum development
|
GO:0022038 |
2 |
0.027
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.027
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.027
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.027
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.027
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.027
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.026
|
|
|
|
protein localization to chromosome centromeric region
|
GO:0071459 |
12 |
0.026
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.026
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.026
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.026
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.026
|
|
|
|
microtubule based transport
|
GO:0010970 |
21 |
0.026
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.026
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.026
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.026
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.026
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.026
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.025
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.025
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.025
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.025
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.025
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.025
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.025
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.025
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.025
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.025
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.025
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.025
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.024
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.024
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.024
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.024
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.024
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.024
|
|
|
|
reciprocal dna recombination
|
GO:0035825 |
4 |
0.024
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.024
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.024
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.024
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.024
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.024
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.024
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.024
|
Fly |
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.023
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.023
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.023
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.023
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.023
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.023
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.023
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.023
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
0.023
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.023
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.023
|
|
|
|
response to mercury ion
|
GO:0046689 |
4 |
0.023
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.023
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.023
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.022
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.022
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.022
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.022
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.022
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.022
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.022
|
|
|
|
kinetochore organization
|
GO:0051383 |
8 |
0.022
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.022
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.022
|
Mouse |
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.022
|
|
|
|
neurofilament cytoskeleton organization
|
GO:0060052 |
2 |
0.022
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.022
|
|
|
|
activation of cdc42 gtpase activity
|
GO:0032864 |
2 |
0.022
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.022
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.022
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.022
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.022
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.022
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.022
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.021
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.021
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.021
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.021
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.021
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.021
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.021
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.021
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.021
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.021
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.021
|
|
|
|
centrosome localization
|
GO:0051642 |
3 |
0.021
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.021
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.021
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.020
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.020
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.020
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.020
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.020
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.020
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
5 |
0.020
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.020
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.020
|
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.020
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.020
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.020
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.020
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.020
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.020
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.020
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.020
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.020
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.020
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.020
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.020
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.019
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.019
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.019
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.019
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.019
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.019
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.019
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.019
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.019
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.019
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.019
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.019
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.019
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.019
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.019
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.019
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.018
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.018
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.018
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
3 |
0.018
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.018
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.018
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.018
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.018
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.018
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.018
|
|
|
|
negative regulation of cytosolic calcium ion concentration
|
GO:0051481 |
1 |
0.018
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.018
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.018
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.018
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.018
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.018
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.018
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.018
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.017
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.017
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.017
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.017
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.017
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.017
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.017
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.017
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.017
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.017
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.017
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.017
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.017
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.016
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.016
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.016
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.016
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.016
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.016
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.016
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.016
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.016
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.016
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
17 |
0.016
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.016
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.016
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.016
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.016
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.016
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.016
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.016
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.016
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.016
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.016
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.015
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.015
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.015
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.015
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.015
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.015
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.015
|
|
