Homo sapiens

126 known processes

CLN3

ceroid-lipofuscinosis, neuronal 3

(Aliases: JNCL,MGC102840,BTS)

CLN3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic anion transport GO:0015711 103 0.851
transmembrane transport GO:0055085 399 0.692
anion transport GO:0006820 161 0.620
single organism carbohydrate metabolic process GO:0044723 193 0.412
inorganic cation transmembrane transport GO:0098662 194 0.412
inorganic ion transmembrane transport GO:0098660 231 0.384
protein glycosylation GO:0006486 62 0.379
post embryonic development GO:0009791 2 0.359
generation of precursor metabolites and energy GO:0006091 68 0.332
carboxylic acid transport GO:0046942 63 0.316
ion transmembrane transport GO:0034220 338 0.314
carbohydrate metabolic process GO:0005975 207 0.305
glycoprotein metabolic process GO:0009100 110 0.292
lipid biosynthetic process GO:0008610 177 0.276
cellular ion homeostasis GO:0006873 168 0.230
oxidation reduction process GO:0055114 396 0.213
glycosylation GO:0070085 71 0.204
cation transmembrane transport GO:0098655 238 0.164
lipid metabolic process GO:0006629 381 0.163
organic acid transport GO:0015849 65 0.154
cellular chemical homeostasis GO:0055082 180 0.120
macromolecule glycosylation GO:0043413 63 0.118
ion homeostasis GO:0050801 230 0.096
regulation of lipid metabolic process GO:0019216 96 0.094
cellular lipid metabolic process GO:0044255 303 0.091
anion transmembrane transport GO:0098656 76 0.088
energy derivation by oxidation of organic compounds GO:0015980 43 0.083
cation transport GO:0006812 331 0.081
atp metabolic process GO:0046034 176 0.078
carbohydrate derivative biosynthetic process GO:1901137 207 0.077
glycoprotein biosynthetic process GO:0009101 91 0.070
monovalent inorganic cation transport GO:0015672 128 0.063
organophosphate biosynthetic process GO:0090407 163 0.059
chemical homeostasis GO:0048878 306 0.058
determination of adult lifespan GO:0008340 2 0.057
single organism membrane organization GO:0044802 268 0.056
protein polymerization GO:0051258 71 0.055
protein modification by small protein conjugation GO:0032446 342 0.050
cellular metal ion homeostasis GO:0006875 146 0.047
cellular macromolecular complex assembly GO:0034622 324 0.044
lipid catabolic process GO:0016042 84 0.043
ribonucleoside monophosphate metabolic process GO:0009161 187 0.041
positive regulation of phospholipase activity GO:0010518 22 0.040
cellular protein complex assembly GO:0043623 188 0.039
multicellular organismal aging GO:0010259 3 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.038
regulation of vesicle mediated transport GO:0060627 130 0.038
metal ion transport GO:0030001 272 0.038
response to abiotic stimulus GO:0009628 336 0.038
amino acid transport GO:0006865 28 0.037
compound eye development GO:0048749 1 0.037
metal ion homeostasis GO:0055065 169 0.035
glycerophospholipid metabolic process GO:0006650 84 0.034
carbohydrate catabolic process GO:0016052 36 0.034
reactive nitrogen species metabolic process GO:2001057 3 0.034
neurological system process GO:0050877 163 0.032
signal transduction by phosphorylation GO:0023014 297 0.032
sensory perception of pain GO:0019233 4 0.032
regulation of defense response GO:0031347 154 0.031
protein maturation GO:0051604 233 0.031
reactive oxygen species metabolic process GO:0072593 75 0.031
positive regulation of lipase activity GO:0060193 28 0.030
defense response GO:0006952 315 0.030
response to biotic stimulus GO:0009607 276 0.030
cellular ketone metabolic process GO:0042180 80 0.030
cellular cation homeostasis GO:0030003 163 0.029
female gamete generation GO:0007292 2 0.029
positive regulation of protein polymerization GO:0032273 45 0.028
nitrogen compound transport GO:0071705 191 0.028
membrane lipid metabolic process GO:0006643 53 0.027
phospholipid metabolic process GO:0006644 99 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.026
cellular response to nutrient levels GO:0031669 69 0.026
peripheral nervous system development GO:0007422 2 0.026
inorganic anion transmembrane transport GO:0098661 47 0.026
protein localization to organelle GO:0033365 280 0.026
cellular homeostasis GO:0019725 196 0.026
cytokine production GO:0001816 247 0.025
regulation of protein polymerization GO:0032271 63 0.025
response to cytokine GO:0034097 232 0.025
oogenesis GO:0048477 2 0.024
system process GO:0003008 349 0.024
cell projection assembly GO:0030031 126 0.024
glycerolipid biosynthetic process GO:0045017 51 0.023
organic acid biosynthetic process GO:0016053 97 0.023
cell type specific apoptotic process GO:0097285 125 0.022
membrane organization GO:0061024 292 0.022
rac protein signal transduction GO:0016601 12 0.022
regulation of cellular response to stress GO:0080135 244 0.022
monocarboxylic acid metabolic process GO:0032787 185 0.022
necrotic cell death GO:0070265 21 0.022
regulation of cellular ketone metabolic process GO:0010565 50 0.022
locomotory behavior GO:0007626 1 0.022
response to external biotic stimulus GO:0043207 261 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
cellular polysaccharide metabolic process GO:0044264 27 0.021
eye development GO:0001654 42 0.021
response to extracellular stimulus GO:0009991 85 0.021
mitochondrial transport GO:0006839 60 0.021
proton transport GO:0015992 22 0.021
response to organic cyclic compound GO:0014070 204 0.021
regulation of actin filament length GO:0030832 56 0.021
cellular amine metabolic process GO:0044106 41 0.021
regulation of reactive oxygen species metabolic process GO:2000377 41 0.020
cofactor metabolic process GO:0051186 87 0.020
positive regulation of actin filament polymerization GO:0030838 38 0.020
regulation of actin filament polymerization GO:0030833 50 0.020
vacuole organization GO:0007033 44 0.020
cellular carbohydrate metabolic process GO:0044262 84 0.020
inorganic anion transport GO:0015698 60 0.019
regulation of actin polymerization or depolymerization GO:0008064 56 0.019
ribose phosphate biosynthetic process GO:0046390 82 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
response to starvation GO:0042594 59 0.019
actin polymerization or depolymerization GO:0008154 56 0.019
regulation of secretion by cell GO:1903530 177 0.018
amine metabolic process GO:0009308 44 0.018
establishment of protein localization to membrane GO:0090150 121 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
cellular amide metabolic process GO:0043603 69 0.018
response to nutrient levels GO:0031667 81 0.017
negative regulation of protein modification process GO:0031400 200 0.017
actin cytoskeleton organization GO:0030036 207 0.017
cellular response to oxygen levels GO:0071453 55 0.017
cell projection organization GO:0030030 252 0.017
regulation of lipase activity GO:0060191 37 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
protein catabolic process GO:0030163 325 0.017
intracellular protein transport GO:0006886 270 0.016
alcohol metabolic process GO:0006066 114 0.016
tetrapyrrole biosynthetic process GO:0033014 7 0.016
response to oxygen levels GO:0070482 100 0.016
cellular response to extracellular stimulus GO:0031668 72 0.016
protein targeting GO:0006605 187 0.016
energy reserve metabolic process GO:0006112 22 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
organophosphate ester transport GO:0015748 32 0.016
steroid biosynthetic process GO:0006694 46 0.016
lipoprotein metabolic process GO:0042157 42 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
cellular glucan metabolic process GO:0006073 22 0.015
positive regulation of cytokine production GO:0001819 167 0.015
secretion by cell GO:0032940 226 0.015
fatty acid metabolic process GO:0006631 115 0.015
response to increased oxygen levels GO:0036296 4 0.015
sodium ion transport GO:0006814 61 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
regulation of protein stability GO:0031647 87 0.015
regulation of mapk cascade GO:0043408 262 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.014
cell growth GO:0016049 160 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
carboxylic acid biosynthetic process GO:0046394 97 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
cell development GO:0048468 328 0.014
positive regulation of organelle organization GO:0010638 195 0.014
divalent metal ion transport GO:0070838 152 0.014
regulation of kinase activity GO:0043549 314 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.013
regulation of protein complex assembly GO:0043254 147 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
neuron death GO:0070997 65 0.013
retina development in camera type eye GO:0060041 15 0.013
positive regulation of transport GO:0051050 336 0.013
response to nitrogen compound GO:1901698 184 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
cation homeostasis GO:0055080 189 0.013
regulation of neuron apoptotic process GO:0043523 35 0.013
response to decreased oxygen levels GO:0036293 96 0.013
immune effector process GO:0002252 159 0.013
positive regulation of defense response GO:0031349 87 0.013
small molecule biosynthetic process GO:0044283 157 0.013
positive regulation of innate immune response GO:0045089 79 0.013
regulation of feeding behavior GO:0060259 3 0.013
regulation of actin filament based process GO:0032970 141 0.013
cellular amino acid metabolic process GO:0006520 116 0.012
regulation of cell development GO:0060284 161 0.012
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.012
innate immune response GO:0045087 178 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
glycerolipid metabolic process GO:0046486 107 0.012
cellular component morphogenesis GO:0032989 314 0.012
polysaccharide catabolic process GO:0000272 4 0.012
regulation of mitochondrion organization GO:0010821 54 0.012
steroid metabolic process GO:0008202 94 0.012
protein localization to membrane GO:0072657 160 0.012
divalent inorganic cation transport GO:0072511 158 0.012
chloride transport GO:0006821 41 0.012
regulation of protein kinase activity GO:0045859 289 0.012
positive regulation of protein complex assembly GO:0031334 86 0.012
positive regulation of apoptotic process GO:0043065 246 0.011
cellular response to external stimulus GO:0071496 111 0.011
renal system development GO:0072001 63 0.011
glycogen metabolic process GO:0005977 22 0.011
regulation of innate immune response GO:0045088 97 0.011
epithelium development GO:0060429 227 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
hemopoiesis GO:0030097 180 0.011
neuromuscular junction development GO:0007528 3 0.011
actin filament polymerization GO:0030041 45 0.011
positive regulation of lipid metabolic process GO:0045834 50 0.010
negative regulation of apoptotic process GO:0043066 316 0.010
response to endoplasmic reticulum stress GO:0034976 49 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
positive regulation of cytoskeleton organization GO:0051495 83 0.010
calcium ion transport GO:0006816 147 0.010
phosphatidic acid biosynthetic process GO:0006654 4 0.010
dephosphorylation GO:0016311 209 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
regulation of cytokine production GO:0001817 232 0.010

CLN3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.656
inherited metabolic disorder DOID:655 242 0.640
central nervous system disease DOID:331 186 0.297
nervous system disease DOID:863 431 0.297
neurodegenerative disease DOID:1289 102 0.090
lysosomal storage disease DOID:3211 47 0.043
immune system disease DOID:2914 155 0.020
carbohydrate metabolic disorder DOID:2978 55 0.014
congenital disorder of glycosylation DOID:5212 26 0.014
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
skin disease DOID:37 33 0.011
integumentary system disease DOID:16 43 0.011
lipid storage disease DOID:9455 28 0.008
neuronal ceroid lipofuscinosis DOID:14503 11 0.008