Homo sapiens

137 known processes

CNOT2

CCR4-NOT transcription complex, subunit 2

(Aliases: NOT2H,FLJ26456,CDC36,NOT2)

CNOT2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of dna templated transcription elongation GO:0032786 18 0.959
regulation of cytoplasmic mrna processing body assembly GO:0010603 5 0.954
positive regulation of cytoplasmic mrna processing body assembly GO:0010606 4 0.946
regulation of stem cell maintenance GO:2000036 4 0.930
cytoplasmic mrna processing body assembly GO:0033962 10 0.923
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.777
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.776
regulation of dna templated transcription elongation GO:0032784 23 0.738
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.686
positive regulation of ligand dependent nuclear receptor transcription coactivator activity GO:2000327 2 0.669
rna phosphodiester bond hydrolysis GO:0090501 35 0.622
dna templated transcription elongation GO:0006354 25 0.600
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.589
trophectodermal cell differentiation GO:0001829 3 0.551
ribonucleoprotein complex assembly GO:0022618 78 0.535
mrna 3 end processing GO:0031124 24 0.534
rna processing GO:0006396 255 0.519
nuclear transcribed mrna poly a tail shortening GO:0000289 8 0.512
determination of adult lifespan GO:0008340 2 0.497
mrna processing GO:0006397 133 0.481
regulation of stem cell differentiation GO:2000736 56 0.434
rna 3 end processing GO:0031123 35 0.426
mrna catabolic process GO:0006402 56 0.394
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.391
stem cell development GO:0048864 69 0.390
cellular macromolecule catabolic process GO:0044265 380 0.381
Fly
mrna metabolic process GO:0016071 175 0.351
Fly
nuclear transcribed mrna catabolic process no go decay GO:0070966 2 0.351
organelle assembly GO:0070925 176 0.349
nuclear transcribed mrna catabolic process GO:0000956 48 0.337
rna catabolic process GO:0006401 71 0.334
Fly
nuclear transcribed mrna catabolic process exonucleolytic GO:0000291 7 0.329
blastocyst formation GO:0001825 3 0.329
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.295
ribonucleoprotein complex subunit organization GO:0071826 81 0.278
mitotic cell cycle phase transition GO:0044772 162 0.266
Fly
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.257
regulation of cellular component biogenesis GO:0044087 281 0.255
multicellular organismal aging GO:0010259 3 0.244
positive regulation of cell proliferation GO:0008284 301 0.233
ribonucleoprotein complex biogenesis GO:0022613 116 0.225
regulation of mitotic cell cycle GO:0007346 189 0.220
Fly
positive regulation of mitotic cell cycle GO:0045931 60 0.219
regulation of cell cycle GO:0051726 393 0.219
Fly
regulation of organelle assembly GO:1902115 40 0.214
regulation of cell cycle phase transition GO:1901987 126 0.208
Fly
vesicle mediated transport GO:0016192 371 0.202
Worm
positive regulation of organelle organization GO:0010638 195 0.202
mitotic cell cycle process GO:1903047 286 0.201
Fly
post embryonic development GO:0009791 2 0.199
Worm
positive regulation of cellular component biogenesis GO:0044089 158 0.196
cell cycle phase transition GO:0044770 173 0.170
Fly
dna dependent dna replication GO:0006261 44 0.168
regulation of cell differentiation GO:0045595 393 0.167
positive regulation of cellular component organization GO:0051130 376 0.162
negative regulation of cell differentiation GO:0045596 171 0.152
dna integrity checkpoint GO:0031570 71 0.151
Fly
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 0.149
anatomical structure formation involved in morphogenesis GO:0048646 284 0.138
negative regulation of developmental process GO:0051093 247 0.134
female gamete generation GO:0007292 2 0.128
stem cell maintenance GO:0019827 19 0.127
negative regulation of dna replication GO:0008156 29 0.126
growth GO:0040007 202 0.117
Worm
positive regulation of cell cycle process GO:0090068 106 0.108
oogenesis GO:0048477 2 0.100
stem cell differentiation GO:0048863 93 0.095
positive regulation of organelle assembly GO:1902117 17 0.093
cell development GO:0048468 328 0.092
positive regulation of catabolic process GO:0009896 310 0.091
translation GO:0006412 132 0.085
Fly
blastocyst development GO:0001824 3 0.083
regulation of meiotic cell cycle GO:0051445 4 0.082
regulation of cell cycle g1 s phase transition GO:1902806 42 0.078
cellular macromolecular complex assembly GO:0034622 324 0.076
dna replication GO:0006260 116 0.076
regulation of ligand dependent nuclear receptor transcription coactivator activity GO:2000325 3 0.075
positive regulation of developmental process GO:0051094 314 0.072
Worm
regulation of dna replication GO:0006275 68 0.071
regulation of mrna metabolic process GO:1903311 53 0.068
negative regulation of dna metabolic process GO:0051053 57 0.067
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 18 0.066
exonucleolytic nuclear transcribed mrna catabolic process involved in deadenylation dependent decay GO:0043928 6 0.063
protein ubiquitination GO:0016567 314 0.062
embryo development GO:0009790 123 0.061
Worm
positive regulation of cell cycle GO:0045787 140 0.060
positive regulation of mrna catabolic process GO:0061014 10 0.058
intracellular receptor signaling pathway GO:0030522 104 0.057
cellular amino acid metabolic process GO:0006520 116 0.054
regulation of dna metabolic process GO:0051052 153 0.053
amine metabolic process GO:0009308 44 0.053
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
Fly
microtubule cytoskeleton organization GO:0000226 176 0.049
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.047
negative regulation of protein metabolic process GO:0051248 391 0.046
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.046
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.045
single organism reproductive process GO:0044702 98 0.044
Worm
regulation of mitotic cell cycle phase transition GO:1901990 118 0.044
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.043
positive regulation of cell cycle phase transition GO:1901989 22 0.042
cell growth GO:0016049 160 0.041
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 8 0.040
regulation of rna stability GO:0043487 23 0.040
regulation of cellular amine metabolic process GO:0033238 11 0.038
positive regulation of meiotic cell cycle GO:0051446 2 0.038
negative regulation of cell proliferation GO:0008285 228 0.037
posttranscriptional regulation of gene expression GO:0010608 213 0.036
Fly
protein modification by small protein conjugation GO:0032446 342 0.035
regulation of cellular ketone metabolic process GO:0010565 50 0.034
microtubule based process GO:0007017 210 0.034
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 8 0.034
negative regulation of dna dependent dna replication GO:2000104 9 0.034
regulation of cell development GO:0060284 161 0.033
mapk cascade GO:0000165 288 0.032
aging GO:0007568 66 0.032
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.031
negative regulation of cellular amine metabolic process GO:0033239 3 0.031
oocyte development GO:0048599 1 0.031
positive regulation of cell death GO:0010942 263 0.030
cellular ketone metabolic process GO:0042180 80 0.030
cellular amine metabolic process GO:0044106 41 0.030
sex differentiation GO:0007548 45 0.029
Worm
neurological system process GO:0050877 163 0.029
protein maturation GO:0051604 233 0.029
regulation of cell cycle process GO:0010564 266 0.029
Fly
reproductive structure development GO:0048608 55 0.028
Worm
immune response GO:0006955 307 0.028
chromatin modification GO:0016568 298 0.028
cell cycle checkpoint GO:0000075 117 0.028
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
negative regulation of cell cycle GO:0045786 193 0.027
Fly
oocyte differentiation GO:0009994 2 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
blastoderm segmentation GO:0007350 2 0.026
wnt signaling pathway GO:0016055 156 0.026
negative regulation of translation GO:0017148 37 0.025
Fly
spindle organization GO:0007051 53 0.025
single organism cellular localization GO:1902580 332 0.025
actin filament based process GO:0030029 224 0.024
mrna destabilization GO:0061157 1 0.024
g1 s transition of mitotic cell cycle GO:0000082 78 0.024
regulation of growth GO:0040008 165 0.024
Worm
leukocyte activation GO:0045321 164 0.024
small gtpase mediated signal transduction GO:0007264 78 0.023
response to nutrient levels GO:0031667 81 0.023
reproductive process GO:0022414 106 0.023
Worm
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.023
protein catabolic process GO:0030163 325 0.023
endocytosis GO:0006897 159 0.022
Worm
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.022
cell projection organization GO:0030030 252 0.022
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 7 0.021
regulation of translation GO:0006417 89 0.021
Fly
dephosphorylation GO:0016311 209 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
small molecule biosynthetic process GO:0044283 157 0.021
response to abiotic stimulus GO:0009628 336 0.021
mitotic cell cycle GO:0000278 326 0.020
Fly
cell cycle g1 s phase transition GO:0044843 80 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
golgi vesicle transport GO:0048193 80 0.020
regulation of dna dependent dna replication GO:0090329 19 0.020
rna destabilization GO:0050779 1 0.019
negative regulation of retinoic acid receptor signaling pathway GO:0048387 4 0.019
protein processing GO:0016485 226 0.019
system process GO:0003008 349 0.019
cell activation GO:0001775 213 0.019
embryo development ending in birth or egg hatching GO:0009792 34 0.018
Worm
memory GO:0007613 3 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
positive regulation of phosphorylation GO:0042327 394 0.018
spermatid differentiation GO:0048515 4 0.018
cell adhesion GO:0007155 325 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
lymphocyte activation GO:0046649 133 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
Fly
positive regulation of cell differentiation GO:0045597 211 0.018
cell division GO:0051301 168 0.017
response to starvation GO:0042594 59 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
angiogenesis GO:0001525 147 0.017
regulation of mrna stability GO:0043488 23 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
negative regulation of protein modification process GO:0031400 200 0.017
regulation of mapk cascade GO:0043408 262 0.017
blood vessel morphogenesis GO:0048514 162 0.017
rab protein signal transduction GO:0032482 4 0.016
spermatid development GO:0007286 4 0.016
apoptotic signaling pathway GO:0097190 268 0.016
regulation of intracellular transport GO:0032386 195 0.016
response to organic cyclic compound GO:0014070 204 0.016
development of primary sexual characteristics GO:0045137 35 0.016
Worm
nitrogen compound transport GO:0071705 191 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
epithelium development GO:0060429 227 0.016
biological adhesion GO:0022610 331 0.016
covalent chromatin modification GO:0016569 254 0.016
reproductive system development GO:0061458 56 0.016
Worm
carbohydrate metabolic process GO:0005975 207 0.016
regulation of protein processing GO:0070613 150 0.016
cell morphogenesis GO:0000902 296 0.016
vasculature development GO:0001944 181 0.015
response to growth factor GO:0070848 205 0.015
purine containing compound catabolic process GO:0072523 411 0.015
nervous system development GO:0007399 293 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
response to extracellular stimulus GO:0009991 85 0.015
regulation of cell activation GO:0050865 125 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
cytoplasmic transport GO:0016482 379 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
dna replication checkpoint GO:0000076 5 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
cellular protein catabolic process GO:0044257 261 0.015
protein methylation GO:0006479 74 0.015
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.014
response to oxygen containing compound GO:1901700 369 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
peptidyl lysine acetylation GO:0018394 101 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.014
ras protein signal transduction GO:0007265 73 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
protein autophosphorylation GO:0046777 123 0.014
negative regulation of cell death GO:0060548 345 0.014
secretion by cell GO:0032940 226 0.014
forelimb morphogenesis GO:0035136 4 0.014
positive regulation of kinase activity GO:0033674 204 0.014
regulation of proteolysis GO:0030162 293 0.014
stem cell division GO:0017145 2 0.014
neuroblast proliferation GO:0007405 4 0.014
mitotic dna damage checkpoint GO:0044773 28 0.014
Fly
canonical wnt signaling pathway GO:0060070 116 0.014
regulation of immune response GO:0050776 201 0.014
regulation of lymphocyte activation GO:0051249 103 0.014
neuromuscular junction development GO:0007528 3 0.014
cellular response to growth factor stimulus GO:0071363 197 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
nucleotide catabolic process GO:0009166 408 0.013
neuron differentiation GO:0030182 138 0.013
immune system development GO:0002520 195 0.013
peptidyl lysine modification GO:0018205 144 0.013
response to fungus GO:0009620 4 0.013
regulation of cellular response to stress GO:0080135 244 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
regulation of meiosis GO:0040020 3 0.013
cellular component morphogenesis GO:0032989 314 0.013
rna splicing via transesterification reactions GO:0000375 90 0.013
positive regulation of immune system process GO:0002684 283 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
ossification GO:0001503 121 0.013
embryonic placenta development GO:0001892 1 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
reproduction GO:0000003 63 0.013
Worm
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
organelle localization GO:0051640 84 0.012
chordate embryonic development GO:0043009 34 0.012
response to external biotic stimulus GO:0043207 261 0.012
response to radiation GO:0009314 151 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
secretion GO:0046903 254 0.012
developmental process involved in reproduction GO:0003006 66 0.012
Worm
rna splicing GO:0008380 131 0.012
long term memory GO:0007616 2 0.012
rna interference GO:0016246 4 0.012
sensory perception GO:0007600 103 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
response to biotic stimulus GO:0009607 276 0.012
positive regulation of transport GO:0051050 336 0.012
dna repair GO:0006281 198 0.011
peripheral nervous system development GO:0007422 2 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
negative regulation of transport GO:0051051 176 0.011
cell fate determination GO:0001709 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
regulation of transferase activity GO:0051338 355 0.011
negative regulation of protein processing GO:0010955 142 0.011
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
innate immune response GO:0045087 178 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
regulation of protein kinase activity GO:0045859 289 0.011
hemopoiesis GO:0030097 180 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
regulation of chromosome organization GO:0033044 103 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
cell part morphogenesis GO:0032990 137 0.011
tripartite regional subdivision GO:0007351 2 0.011
maintenance of location GO:0051235 112 0.011
Worm
positive regulation of growth GO:0045927 58 0.011
Worm
peptidyl tyrosine modification GO:0018212 170 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
inner ear morphogenesis GO:0042472 4 0.011
chemical homeostasis GO:0048878 306 0.011
protein acylation GO:0043543 138 0.011
central nervous system development GO:0007417 123 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.011
tissue regeneration GO:0042246 3 0.011
organophosphate catabolic process GO:0046434 430 0.011
negative regulation of immune system process GO:0002683 136 0.011
cilium morphogenesis GO:0060271 75 0.011
chromatin organization GO:0006325 351 0.011
regeneration GO:0031099 4 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
regulation of response to external stimulus GO:0032101 222 0.011
regulation of kinase activity GO:0043549 314 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
protein localization to organelle GO:0033365 280 0.010
metal ion transport GO:0030001 272 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
transmembrane transport GO:0055085 399 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.010
positive regulation of transferase activity GO:0051347 227 0.010
regulation of endopeptidase activity GO:0052548 170 0.010
stress activated protein kinase signaling cascade GO:0031098 94 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
nuclear transport GO:0051169 179 0.010
metencephalon development GO:0022037 2 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
actin cytoskeleton organization GO:0030036 207 0.010

CNOT2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.017
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
sensory system disease DOID:0050155 203 0.010
nervous system disease DOID:863 431 0.010