Homo sapiens

36 known processes

COG4

component of oligomeric golgi complex 4

(Aliases: DKFZp586E1519,CDG2J,COD1)

COG4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glycosylation GO:0070085 71 0.546
golgi vesicle transport GO:0048193 80 0.455
carbohydrate derivative biosynthetic process GO:1901137 207 0.424
macromolecule glycosylation GO:0043413 63 0.357
retrograde vesicle mediated transport golgi to er GO:0006890 8 0.349
protein glycosylation GO:0006486 62 0.294
glycoprotein biosynthetic process GO:0009101 91 0.257
single organism carbohydrate metabolic process GO:0044723 193 0.206
vesicle mediated transport GO:0016192 371 0.165
carbohydrate metabolic process GO:0005975 207 0.165
protein localization to organelle GO:0033365 280 0.135
Yeast
regulation of protein stability GO:0031647 87 0.129
posttranscriptional regulation of gene expression GO:0010608 213 0.103
glycoprotein metabolic process GO:0009100 110 0.097
regeneration GO:0031099 4 0.091
protein stabilization GO:0050821 64 0.079
cellular protein complex assembly GO:0043623 188 0.078
post embryonic development GO:0009791 2 0.074
Worm
cytoplasmic transport GO:0016482 379 0.064
Yeast
intracellular protein transport GO:0006886 270 0.061
Yeast
mitotic cell cycle process GO:1903047 286 0.058
single organism membrane fusion GO:0044801 37 0.050
cellular macromolecular complex assembly GO:0034622 324 0.046
tissue regeneration GO:0042246 3 0.046
female gamete generation GO:0007292 2 0.045
Worm
protein modification by small protein conjugation GO:0032446 342 0.043
protein ubiquitination GO:0016567 314 0.042
protein catabolic process GO:0030163 325 0.042
snare complex assembly GO:0035493 3 0.041
cellular amino acid metabolic process GO:0006520 116 0.040
positive regulation of phosphorylation GO:0042327 394 0.040
er to golgi vesicle mediated transport GO:0006888 19 0.040
cellular macromolecule catabolic process GO:0044265 380 0.040
regulation of cellular amine metabolic process GO:0033238 11 0.039
nucleotide catabolic process GO:0009166 408 0.038
cofactor metabolic process GO:0051186 87 0.038
positive regulation of transport GO:0051050 336 0.037
cellular amine metabolic process GO:0044106 41 0.036
multicellular organismal aging GO:0010259 3 0.036
cofactor biosynthetic process GO:0051188 31 0.036
ribonucleotide catabolic process GO:0009261 405 0.035
purine nucleoside triphosphate catabolic process GO:0009146 392 0.035
nucleoside phosphate catabolic process GO:1901292 412 0.034
regulation of cellular component biogenesis GO:0044087 281 0.034
regulation of protein complex assembly GO:0043254 147 0.034
cytokinesis GO:0000910 96 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.033
purine nucleotide catabolic process GO:0006195 405 0.032
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
amine metabolic process GO:0009308 44 0.031
vesicle organization GO:0016050 62 0.031
protein processing GO:0016485 226 0.031
membrane organization GO:0061024 292 0.031
negative regulation of protein metabolic process GO:0051248 391 0.030
glycosyl compound catabolic process GO:1901658 413 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.030
positive regulation of organelle organization GO:0010638 195 0.029
cellular ketone metabolic process GO:0042180 80 0.029
nucleoside catabolic process GO:0009164 408 0.029
dna repair GO:0006281 198 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
lipid metabolic process GO:0006629 381 0.028
ubiquitin dependent protein catabolic process GO:0006511 206 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of vesicle mediated transport GO:0060627 130 0.027
regulation of kinase activity GO:0043549 314 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.027
neuroblast proliferation GO:0007405 4 0.027
mitotic cell cycle GO:0000278 326 0.026
purine nucleoside triphosphate metabolic process GO:0009144 412 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
positive regulation of cellular component organization GO:0051130 376 0.026
regulation of transferase activity GO:0051338 355 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
oogenesis GO:0048477 2 0.025
Worm
gtp metabolic process GO:0046039 239 0.025
growth GO:0040007 202 0.025
modification dependent protein catabolic process GO:0019941 209 0.025
histone modification GO:0016570 251 0.025
endosomal transport GO:0016197 129 0.024
single organism membrane organization GO:0044802 268 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
organelle assembly GO:0070925 176 0.024
vesicle fusion GO:0006906 17 0.024
response to wounding GO:0009611 168 0.023
positive regulation of vesicle fusion GO:0031340 4 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
mitotic cell cycle phase transition GO:0044772 162 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
apoptotic signaling pathway GO:0097190 268 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
oocyte development GO:0048599 1 0.022
regulation of protein kinase activity GO:0045859 289 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
neurotransmitter secretion GO:0007269 4 0.022
endomembrane system organization GO:0010256 196 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
cell cycle phase transition GO:0044770 173 0.022
protein maturation GO:0051604 233 0.022
protein oligomerization GO:0051259 173 0.021
organelle fusion GO:0048284 36 0.021
lipid biosynthetic process GO:0008610 177 0.021
cell division GO:0051301 168 0.021
positive regulation of cellular component biogenesis GO:0044089 158 0.021
nervous system development GO:0007399 293 0.021
actin filament based process GO:0030029 224 0.021
cell projection organization GO:0030030 252 0.020
cellular protein catabolic process GO:0044257 261 0.020
regulation of cell cycle process GO:0010564 266 0.020
single organism cellular localization GO:1902580 332 0.020
Yeast
organophosphate biosynthetic process GO:0090407 163 0.020
negative regulation of cell cycle GO:0045786 193 0.020
membrane fusion GO:0061025 43 0.020
neuromuscular junction development GO:0007528 3 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.019
negative regulation of protein maturation GO:1903318 142 0.019
regulation of cell cycle GO:0051726 393 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
secretion GO:0046903 254 0.019
ras protein signal transduction GO:0007265 73 0.018
defense response GO:0006952 315 0.018
purine containing compound catabolic process GO:0072523 411 0.018
cellular component disassembly GO:0022411 92 0.018
golgi organization GO:0007030 38 0.018
negative regulation of protein processing GO:0010955 142 0.018
determination of adult lifespan GO:0008340 2 0.018
regulation of neurotransmitter secretion GO:0046928 3 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
positive regulation of developmental process GO:0051094 314 0.018
protein acetylation GO:0006473 116 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
maintenance of location GO:0051235 112 0.018
Worm
cell morphogenesis GO:0000902 296 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
nuclear division GO:0000280 128 0.018
mitotic nuclear division GO:0007067 119 0.017
regulation of protein maturation GO:1903317 150 0.017
mapk cascade GO:0000165 288 0.017
actin cytoskeleton organization GO:0030036 207 0.017
positive regulation of cell death GO:0010942 263 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
gtp catabolic process GO:0006184 237 0.017
small molecule biosynthetic process GO:0044283 157 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
oocyte differentiation GO:0009994 2 0.017
rna processing GO:0006396 255 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
chromatin modification GO:0016568 298 0.016
organophosphate catabolic process GO:0046434 430 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
regulation of protein processing GO:0070613 150 0.016
cellular lipid metabolic process GO:0044255 303 0.016
locomotory behavior GO:0007626 1 0.016
blastoderm segmentation GO:0007350 2 0.016
cellular component morphogenesis GO:0032989 314 0.016
neurogenesis GO:0022008 169 0.016
response to axon injury GO:0048678 1 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
regulation of proteolysis GO:0030162 293 0.015
secretion by cell GO:0032940 226 0.015
negative regulation of cell death GO:0060548 345 0.015
regulation of neuroblast proliferation GO:1902692 3 0.015
regulation of cellular response to stress GO:0080135 244 0.015
meiosis i GO:0007127 4 0.015
regulation of cell diameter GO:0060305 1 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
organelle fission GO:0048285 149 0.015
cilium morphogenesis GO:0060271 75 0.015
regulation of proteasomal protein catabolic process GO:0061136 87 0.015
segmentation GO:0035282 4 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.014
hindbrain development GO:0030902 3 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
thymus development GO:0048538 3 0.014
cell projection assembly GO:0030031 126 0.014
protein localization to golgi apparatus GO:0034067 13 0.014
metencephalon development GO:0022037 2 0.014
endocytosis GO:0006897 159 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
peripheral nervous system development GO:0007422 2 0.014
regulation of protein catabolic process GO:0042176 155 0.014
cellular cation homeostasis GO:0030003 163 0.014
macromolecule methylation GO:0043414 97 0.014
synaptic vesicle exocytosis GO:0016079 3 0.014
response to biotic stimulus GO:0009607 276 0.014
immune response GO:0006955 307 0.014
regulation of response to external stimulus GO:0032101 222 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
regulation of synaptic vesicle transport GO:1902803 3 0.014
axon cargo transport GO:0008088 2 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
coenzyme metabolic process GO:0006732 65 0.013
positive regulation of protein complex assembly GO:0031334 86 0.013
dephosphorylation GO:0016311 209 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
response to oxygen containing compound GO:1901700 369 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
covalent chromatin modification GO:0016569 254 0.013
compound eye development GO:0048749 1 0.013
positive regulation of kinase activity GO:0033674 204 0.013
regulation of growth GO:0040008 165 0.013
response to fungus GO:0009620 4 0.013
chromosome segregation GO:0007059 114 0.013
response to abiotic stimulus GO:0009628 336 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
regulation of protein ubiquitination GO:0031396 95 0.013
oxidation reduction process GO:0055114 396 0.013
anterior posterior axis specification GO:0009948 2 0.013
regulation of protein localization GO:0032880 296 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
spermatid development GO:0007286 4 0.013
negative regulation of cellular component organization GO:0051129 235 0.012
translation GO:0006412 132 0.012
regulation of cell differentiation GO:0045595 393 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
regulation of cell motility GO:2000145 299 0.012
Worm
regulation of gtpase activity GO:0043087 180 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
memory GO:0007613 3 0.012
cell growth GO:0016049 160 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
negative regulation of proteolysis GO:0045861 132 0.012
phospholipid metabolic process GO:0006644 99 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
response to external biotic stimulus GO:0043207 261 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
methylation GO:0032259 106 0.012
cilium assembly GO:0042384 63 0.012
regulation of mapk cascade GO:0043408 262 0.012
viral process GO:0016032 146 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
cilium organization GO:0044782 68 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
visual behavior GO:0007632 2 0.011
cell part morphogenesis GO:0032990 137 0.011
single organism reproductive process GO:0044702 98 0.011
Worm
cellular metal ion homeostasis GO:0006875 146 0.011
cell development GO:0048468 328 0.011
Worm
generation of neurons GO:0048699 152 0.011
spermatid differentiation GO:0048515 4 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
microtubule based process GO:0007017 210 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
cellular response to external stimulus GO:0071496 111 0.011
Yeast
cytokine production GO:0001816 247 0.011
macromolecular complex disassembly GO:0032984 60 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
g1 s transition of mitotic cell cycle GO:0000082 78 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
Yeast
negative regulation of intracellular signal transduction GO:1902532 183 0.011
associative learning GO:0008306 1 0.011
adult locomotory behavior GO:0008344 1 0.011
negative regulation of organelle organization GO:0010639 126 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
negative regulation of catabolic process GO:0009895 104 0.011
protein localization to membrane GO:0072657 160 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
chromatin organization GO:0006325 351 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
cation homeostasis GO:0055080 189 0.011
response to other organism GO:0051707 261 0.011
rhythmic behavior GO:0007622 2 0.011
negative regulation of phosphorylation GO:0042326 174 0.010
eye photoreceptor cell differentiation GO:0001754 2 0.010
organ formation GO:0048645 3 0.010
reproduction GO:0000003 63 0.010
Worm
axon regeneration GO:0031103 1 0.010
multi organism cellular process GO:0044764 156 0.010
mitochondrion organization GO:0007005 156 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010
atp metabolic process GO:0046034 176 0.010
nerve development GO:0021675 4 0.010
inner ear morphogenesis GO:0042472 4 0.010
purine containing compound biosynthetic process GO:0072522 88 0.010
establishment of protein localization to membrane GO:0090150 121 0.010
internal peptidyl lysine acetylation GO:0018393 97 0.010
positive regulation of catabolic process GO:0009896 310 0.010
viral life cycle GO:0019058 132 0.010
regulation of secretion by cell GO:1903530 177 0.010
negative regulation of blood pressure GO:0045776 3 0.010
glycerophospholipid metabolic process GO:0006650 84 0.010
positive regulation of immune system process GO:0002684 283 0.010
negative regulation of developmental process GO:0051093 247 0.010
regulation of gtp catabolic process GO:0033124 180 0.010
metal ion transport GO:0030001 272 0.010
cell projection morphogenesis GO:0048858 129 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
developmental programmed cell death GO:0010623 3 0.010

COG4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 1.000
carbohydrate metabolic disorder DOID:2978 55 1.000
congenital disorder of glycosylation DOID:5212 26 1.000
inherited metabolic disorder DOID:655 242 1.000
congenital disorder of glycosylation type ii DOID:0050571 10 0.992
musculoskeletal system disease DOID:17 223 0.022
sensory system disease DOID:0050155 203 0.021
eye and adnexa disease DOID:1492 150 0.021
nervous system disease DOID:863 431 0.021
eye disease DOID:5614 149 0.021
cancer DOID:162 167 0.020
disease of cellular proliferation DOID:14566 174 0.020
organ system cancer DOID:0050686 164 0.016
muscular disease DOID:0080000 114 0.016
muscle tissue disease DOID:66 113 0.016
myopathy DOID:423 104 0.015
porphyria DOID:13268 8 0.014
connective tissue disease DOID:65 109 0.013
retinal disease DOID:5679 118 0.013
cardiovascular system disease DOID:1287 106 0.011
central nervous system disease DOID:331 186 0.011
disease of mental health DOID:150 70 0.010
immune system disease DOID:2914 155 0.010
bone disease DOID:0080001 88 0.010
retinal degeneration DOID:8466 89 0.010