Homo sapiens

17 known processes

COPS6

COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)

(Aliases: CSN6,MOV34-34KD)

COPS6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein removal GO:0070646 92 0.999
cullin deneddylation GO:0010388 9 0.998
mitotic cell cycle GO:0000278 326 0.986
Fly
cell cell signaling involved in cell fate commitment GO:0045168 5 0.971
Fly
protein deneddylation GO:0000338 10 0.970
negative regulation of cell cycle process GO:0010948 121 0.940
Fly
cell cycle phase transition GO:0044770 173 0.918
Fly
regulation of mitotic cell cycle phase transition GO:1901990 118 0.897
Fly
regulation of cell cycle process GO:0010564 266 0.890
Fly
post embryonic development GO:0009791 2 0.885
cellular response to dna damage stimulus GO:0006974 379 0.850
Fly
g2 dna damage checkpoint GO:0031572 26 0.841
Fly
regulation of mitotic cell cycle GO:0007346 189 0.838
Fly
mitotic dna damage checkpoint GO:0044773 28 0.832
Fly
regulation of transferase activity GO:0051338 355 0.824
negative regulation of cell proliferation GO:0008285 228 0.813
ubiquitin dependent protein catabolic process GO:0006511 206 0.768
modification dependent protein catabolic process GO:0019941 209 0.697
cellular protein catabolic process GO:0044257 261 0.687
dna integrity checkpoint GO:0031570 71 0.639
Fly
mitotic cell cycle process GO:1903047 286 0.629
Fly
cellular macromolecule catabolic process GO:0044265 380 0.562
regulation of cell cycle GO:0051726 393 0.529
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.496
mitotic cell cycle phase transition GO:0044772 162 0.476
Fly
cell development GO:0048468 328 0.446
regulation of cellular amino acid metabolic process GO:0006521 6 0.439
protein modification by small protein conjugation GO:0032446 342 0.418
vesicle mediated transport GO:0016192 371 0.390
dna damage checkpoint GO:0000077 68 0.358
Fly
regulation of protein serine threonine kinase activity GO:0071900 179 0.335
negative regulation of cell cycle phase transition GO:1901988 89 0.325
Fly
negative regulation of cell death GO:0060548 345 0.315
embryo development GO:0009790 123 0.311
Worm
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.304
posttranscriptional regulation of gene expression GO:0010608 213 0.291
Fly
female gamete generation GO:0007292 2 0.283
negative regulation of mitotic cell cycle GO:0045930 102 0.261
Fly
negative regulation of programmed cell death GO:0043069 321 0.252
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.243
Fly
mitotic g2 m transition checkpoint GO:0044818 9 0.238
Fly
chromosome segregation GO:0007059 114 0.230
proteasomal protein catabolic process GO:0010498 176 0.220
regulation of cell cycle phase transition GO:1901987 126 0.208
Fly
negative regulation of cell cycle GO:0045786 193 0.205
Fly
positive regulation of protein catabolic process GO:0045732 75 0.199
regulation of protein catabolic process GO:0042176 155 0.186
mapk cascade GO:0000165 288 0.174
regulation of cellular protein catabolic process GO:1903362 96 0.172
cell cycle checkpoint GO:0000075 117 0.165
Fly
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.161
modification dependent macromolecule catabolic process GO:0043632 212 0.161
cellular ketone metabolic process GO:0042180 80 0.155
segmentation GO:0035282 4 0.151
positive regulation of proteolysis GO:0045862 142 0.145
cellular amine metabolic process GO:0044106 41 0.141
oogenesis GO:0048477 2 0.135
positive regulation of catabolic process GO:0009896 310 0.131
negative regulation of apoptotic process GO:0043066 316 0.126
regulation of protein kinase activity GO:0045859 289 0.125
ribonucleoside monophosphate metabolic process GO:0009161 187 0.123
protein catabolic process GO:0030163 325 0.122
regulation of proteolysis GO:0030162 293 0.117
positive regulation of alcohol biosynthetic process GO:1902932 9 0.103
protein targeting GO:0006605 187 0.101
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.097
regulation of response to biotic stimulus GO:0002831 55 0.093
mitotic cell cycle checkpoint GO:0007093 68 0.093
Fly
regulation of mapk cascade GO:0043408 262 0.091
negative regulation of protein metabolic process GO:0051248 391 0.089
negative regulation of phosphorus metabolic process GO:0010563 267 0.088
regulation of establishment of protein localization GO:0070201 242 0.086
protein stabilization GO:0050821 64 0.084
Fly
cyclin catabolic process GO:0008054 6 0.083
mitotic nuclear division GO:0007067 119 0.082
multicellular organismal aging GO:0010259 3 0.082
internal protein amino acid acetylation GO:0006475 101 0.077
receptor mediated endocytosis GO:0006898 84 0.074
negative regulation of immune system process GO:0002683 136 0.074
regulation of kinase activity GO:0043549 314 0.072
organelle fission GO:0048285 149 0.072
hematopoietic or lymphoid organ development GO:0048534 186 0.066
defense response GO:0006952 315 0.064
lipid metabolic process GO:0006629 381 0.064
regulation of proteasomal protein catabolic process GO:0061136 87 0.062
cellular amino acid metabolic process GO:0006520 116 0.058
fibroblast proliferation GO:0048144 33 0.053
mitotic g2 dna damage checkpoint GO:0007095 7 0.053
Fly
endocytosis GO:0006897 159 0.053
lipid localization GO:0010876 106 0.053
defense response to other organism GO:0098542 129 0.052
regulation of cellular amine metabolic process GO:0033238 11 0.051
intracellular protein transport GO:0006886 270 0.050
response to oxygen containing compound GO:1901700 369 0.050
apoptotic signaling pathway GO:0097190 268 0.049
protein maturation GO:0051604 233 0.049
cell fate commitment GO:0045165 27 0.049
Fly
protein ubiquitination GO:0016567 314 0.049
protein methylation GO:0006479 74 0.049
regulation of translation GO:0006417 89 0.047
neuron differentiation GO:0030182 138 0.045
blastoderm segmentation GO:0007350 2 0.043
nucleoside monophosphate metabolic process GO:0009123 191 0.042
negative regulation of protein catabolic process GO:0042177 59 0.042
amine metabolic process GO:0009308 44 0.042
regulation of intracellular protein transport GO:0033157 123 0.041
intrinsic apoptotic signaling pathway GO:0097193 127 0.041
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.038
regulation of response to external stimulus GO:0032101 222 0.037
immune effector process GO:0002252 159 0.037
protein processing GO:0016485 226 0.037
nuclear import GO:0051170 106 0.037
cell part morphogenesis GO:0032990 137 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.034
protein localization to organelle GO:0033365 280 0.033
regulation of protein stability GO:0031647 87 0.032
Fly
lipid biosynthetic process GO:0008610 177 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
negative regulation of response to external stimulus GO:0032102 83 0.031
reproductive process GO:0022414 106 0.031
nervous system development GO:0007399 293 0.030
cell cell signaling GO:0007267 155 0.029
Fly
regulation of nucleocytoplasmic transport GO:0046822 98 0.028
oocyte differentiation GO:0009994 2 0.028
negative regulation of fibroblast proliferation GO:0048147 12 0.028
central nervous system development GO:0007417 123 0.028
protein acylation GO:0043543 138 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
cell division GO:0051301 168 0.027
Worm
generation of precursor metabolites and energy GO:0006091 68 0.027
negative regulation of cellular protein catabolic process GO:1903363 38 0.026
stress activated mapk cascade GO:0051403 93 0.026
reproduction GO:0000003 63 0.026
Worm
methylation GO:0032259 106 0.025
positive regulation of mitotic cell cycle spindle assembly checkpoint GO:0090267 6 0.025
mitotic dna integrity checkpoint GO:0044774 30 0.025
Fly
nuclear export GO:0051168 69 0.025
regulation of cytokine production GO:0001817 232 0.025
cell projection organization GO:0030030 252 0.025
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.025
negative regulation of transferase activity GO:0051348 124 0.024
multicellular organism reproduction GO:0032504 42 0.024
positive regulation of cellular protein catabolic process GO:1903364 37 0.024
negative regulation of protein transport GO:0051224 75 0.024
single organism cellular localization GO:1902580 332 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
cytokine production GO:0001816 247 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
positive regulation of cell cycle GO:0045787 140 0.022
neuron development GO:0048666 113 0.021
response to cytokine GO:0034097 232 0.021
positive regulation of spindle checkpoint GO:0090232 7 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
protein targeting to nucleus GO:0044744 104 0.021
protein localization to nucleus GO:0034504 136 0.021
cytokinesis GO:0000910 96 0.021
Worm
neurogenesis GO:0022008 169 0.021
cellular response to growth factor stimulus GO:0071363 197 0.020
regulation of cellular response to stress GO:0080135 244 0.020
neuron projection morphogenesis GO:0048812 50 0.020
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
cellular response to uv GO:0034644 32 0.020
regulation of cell cycle g1 s phase transition GO:1902806 42 0.020
rho protein signal transduction GO:0007266 26 0.020
negative regulation of kinase activity GO:0033673 106 0.019
defense response to virus GO:0051607 71 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
negative regulation of cell growth GO:0030308 83 0.018
regulation of fibroblast proliferation GO:0048145 32 0.018
negative regulation of catabolic process GO:0009895 104 0.018
cytoplasmic transport GO:0016482 379 0.018
regulation of protein processing GO:0070613 150 0.018
maintenance of location GO:0051235 112 0.017
ncrna metabolic process GO:0034660 108 0.016
response to reactive oxygen species GO:0000302 61 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
purine nucleotide catabolic process GO:0006195 405 0.016
multicellular organismal reproductive process GO:0048609 40 0.016
myeloid cell differentiation GO:0030099 117 0.016
protein homooligomerization GO:0051260 100 0.016
mitotic sister chromatid separation GO:0051306 18 0.015
regulation of centriole replication GO:0046599 7 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
chromatin organization GO:0006325 351 0.014
negative regulation of intracellular protein transport GO:0090317 42 0.014
negative regulation of developmental process GO:0051093 247 0.014
cellular response to light stimulus GO:0071482 34 0.014
nuclear division GO:0000280 128 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.014
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.014
negative regulation of cytoplasmic transport GO:1903650 46 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
immune response GO:0006955 307 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.013
multi organism reproductive process GO:0044703 54 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
immune system development GO:0002520 195 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
protein acetylation GO:0006473 116 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
system process GO:0003008 349 0.012
sex differentiation GO:0007548 45 0.012
secretion by cell GO:0032940 226 0.012
nuclear transport GO:0051169 179 0.012
dna dependent dna replication GO:0006261 44 0.012
wnt signaling pathway GO:0016055 156 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
regulation of protein targeting GO:1903533 91 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
aging GO:0007568 66 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
regulation of mitotic cell cycle spindle assembly checkpoint GO:0090266 8 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
golgi vesicle transport GO:0048193 80 0.011
cardiovascular system development GO:0072358 262 0.011
protein deubiquitination GO:0016579 79 0.011
positive regulation of cell cycle process GO:0090068 106 0.011
reactive oxygen species metabolic process GO:0072593 75 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
protein oligomerization GO:0051259 173 0.010
positive regulation of apoptotic process GO:0043065 246 0.010
stress activated protein kinase signaling cascade GO:0031098 94 0.010
growth GO:0040007 202 0.010
negative regulation of myeloid cell differentiation GO:0045638 42 0.010

COPS6 disease predictions

Disease DO term ID Size Probability Func Analog Org