Homo sapiens

31 known processes

CP110

CP110 protein

(Aliases: KIAA0419,Cep110,DKFZp781G1416)

CP110 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule organizing center organization GO:0031023 62 0.571
centrosome organization GO:0051297 58 0.534
centrosome cycle GO:0007098 32 0.415
regulation of cytoskeleton organization GO:0051493 177 0.410
notch signaling pathway GO:0007219 31 0.366
regulation of cell cycle process GO:0010564 266 0.357
regulation of microtubule based process GO:0032886 74 0.346
organelle assembly GO:0070925 176 0.329
protein modification by small protein conjugation GO:0032446 342 0.320
regulation of microtubule cytoskeleton organization GO:0070507 61 0.279
female gamete generation GO:0007292 2 0.278
positive regulation of adenylate cyclase activity GO:0045762 12 0.264
negative regulation of cell cycle GO:0045786 193 0.257
nucleoside phosphate biosynthetic process GO:1901293 109 0.245
regulation of centrosome cycle GO:0046605 15 0.244
regulation of cell cycle GO:0051726 393 0.227
negative regulation of cell cycle process GO:0010948 121 0.214
microtubule cytoskeleton organization GO:0000226 176 0.210
negative regulation of organelle organization GO:0010639 126 0.197
negative regulation of cell proliferation GO:0008285 228 0.181
negative regulation of cytoskeleton organization GO:0051494 45 0.138
protein catabolic process GO:0030163 325 0.132
positive regulation of programmed cell death GO:0043068 249 0.122
cilium assembly GO:0042384 63 0.121
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 15 0.101
mitotic nuclear division GO:0007067 119 0.100
positive regulation of camp biosynthetic process GO:0030819 35 0.098
positive regulation of cell death GO:0010942 263 0.094
regulation of cell division GO:0051302 116 0.093
positive regulation of apoptotic process GO:0043065 246 0.092
nucleotide biosynthetic process GO:0009165 109 0.092
cellular protein catabolic process GO:0044257 261 0.092
cellular macromolecule catabolic process GO:0044265 380 0.085
anatomical structure formation involved in morphogenesis GO:0048646 284 0.085
negative regulation of notch signaling pathway GO:0045746 10 0.085
proteasomal protein catabolic process GO:0010498 176 0.082
g protein coupled receptor signaling pathway GO:0007186 207 0.082
positive regulation of dna replication GO:0045740 35 0.080
cyclic nucleotide metabolic process GO:0009187 82 0.079
cytokinesis GO:0000910 96 0.077
cell division GO:0051301 168 0.077
cyclic nucleotide biosynthetic process GO:0009190 61 0.074
regulation of camp metabolic process GO:0030814 52 0.072
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.071
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.070
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.068
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.066
enzyme linked receptor protein signaling pathway GO:0007167 303 0.065
cellular component morphogenesis GO:0032989 314 0.065
cell cycle checkpoint GO:0000075 117 0.063
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.062
somatic stem cell division GO:0048103 1 0.061
regulation of intracellular transport GO:0032386 195 0.061
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.060
regulation of protein serine threonine kinase activity GO:0071900 179 0.060
protein deubiquitination GO:0016579 79 0.058
cilium morphogenesis GO:0060271 75 0.058
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.058
mitotic cell cycle phase transition GO:0044772 162 0.057
cellular amino acid metabolic process GO:0006520 116 0.056
microtubule based process GO:0007017 210 0.055
cell projection assembly GO:0030031 126 0.054
positive regulation of cellular component biogenesis GO:0044089 158 0.054
negative regulation of rho gtpase activity GO:0034259 4 0.053
mitotic cytokinesis GO:0000281 19 0.053
positive regulation of cellular component organization GO:0051130 376 0.051
positive regulation of kinase activity GO:0033674 204 0.050
regulation of epithelial cell proliferation GO:0050678 113 0.050
regulation of protein localization GO:0032880 296 0.048
regulation of organelle assembly GO:1902115 40 0.047
ribonucleotide biosynthetic process GO:0009260 81 0.047
cellular macromolecular complex assembly GO:0034622 324 0.047
purine nucleotide catabolic process GO:0006195 405 0.045
mapk cascade GO:0000165 288 0.045
response to other organism GO:0051707 261 0.044
positive regulation of cell proliferation GO:0008284 301 0.044
purine nucleotide biosynthetic process GO:0006164 84 0.044
cell morphogenesis GO:0000902 296 0.044
positive regulation of transferase activity GO:0051347 227 0.044
organophosphate biosynthetic process GO:0090407 163 0.043
oocyte differentiation GO:0009994 2 0.043
camp biosynthetic process GO:0006171 47 0.043
regulation of mitotic cell cycle phase transition GO:1901990 118 0.042
cilium organization GO:0044782 68 0.042
carbohydrate derivative biosynthetic process GO:1901137 207 0.042
dephosphorylation GO:0016311 209 0.042
modification dependent protein catabolic process GO:0019941 209 0.042
positive regulation of dna metabolic process GO:0051054 73 0.041
microtubule polymerization or depolymerization GO:0031109 37 0.041
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.040
negative regulation of cell cycle phase transition GO:1901988 89 0.040
modification dependent macromolecule catabolic process GO:0043632 212 0.040
regulation of dna metabolic process GO:0051052 153 0.039
regulation of cellular component biogenesis GO:0044087 281 0.039
purine ribonucleotide biosynthetic process GO:0009152 79 0.039
positive regulation of protein phosphorylation GO:0001934 313 0.039
oogenesis GO:0048477 2 0.038
positive regulation of organelle organization GO:0010638 195 0.038
positive regulation of camp metabolic process GO:0030816 41 0.038
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.038
muscle contraction GO:0006936 73 0.037
multicellular organismal aging GO:0010259 3 0.037
cardiovascular system development GO:0072358 262 0.037
ras protein signal transduction GO:0007265 73 0.036
nuclear division GO:0000280 128 0.036
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.035
regulation of transcription by galactose GO:0000409 1 0.035
ubiquitin dependent protein catabolic process GO:0006511 206 0.035
negative regulation of phosphate metabolic process GO:0045936 267 0.035
positive regulation of ras gtpase activity GO:0032320 117 0.035
regulation of dna replication GO:0006275 68 0.035
peptidyl serine modification GO:0018209 106 0.035
regulation of centrosome duplication GO:0010824 14 0.034
positive regulation of nucleotide catabolic process GO:0030813 185 0.034
positive regulation of protein transport GO:0051222 135 0.034
negative regulation of mitotic cell cycle GO:0045930 102 0.033
neuromuscular junction development GO:0007528 3 0.033
mrna splicing via spliceosome GO:0000398 89 0.032
protein ubiquitination GO:0016567 314 0.032
regulation of cellular amine metabolic process GO:0033238 11 0.032
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.032
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.031
regulation of angiogenesis GO:0045765 92 0.031
vesicle mediated transport GO:0016192 371 0.031
peptidyl serine phosphorylation GO:0018105 101 0.030
growth GO:0040007 202 0.030
regulation of nucleotide biosynthetic process GO:0030808 50 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
maintenance of location GO:0051235 112 0.030
regulation of transferase activity GO:0051338 355 0.029
signal transduction by phosphorylation GO:0023014 297 0.029
ion homeostasis GO:0050801 230 0.029
purine containing compound catabolic process GO:0072523 411 0.029
organophosphate catabolic process GO:0046434 430 0.029
locomotory behavior GO:0007626 1 0.029
angiogenesis GO:0001525 147 0.029
regulation of actin filament based process GO:0032970 141 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
peptidyl threonine modification GO:0018210 45 0.028
centrosome duplication GO:0051298 28 0.028
protein localization to organelle GO:0033365 280 0.027
oxidation reduction process GO:0055114 396 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.027
regulation of cell cycle phase transition GO:1901987 126 0.027
positive regulation of protein kinase activity GO:0045860 190 0.027
apoptotic signaling pathway GO:0097190 268 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
cellular senescence GO:0090398 34 0.027
post embryonic development GO:0009791 2 0.027
regulation of establishment of protein localization GO:0070201 242 0.026
mitotic cell cycle checkpoint GO:0007093 68 0.026
negative regulation of catabolic process GO:0009895 104 0.026
cellular response to external stimulus GO:0071496 111 0.026
regulation of cellular component movement GO:0051270 334 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
stem cell development GO:0048864 69 0.026
protein oligomerization GO:0051259 173 0.026
purine ribonucleoside catabolic process GO:0046130 398 0.026
regulation of camp biosynthetic process GO:0030817 45 0.026
cellular ketone metabolic process GO:0042180 80 0.026
chemical homeostasis GO:0048878 306 0.025
secretion by cell GO:0032940 226 0.025
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.025
negative regulation of intracellular signal transduction GO:1902532 183 0.025
regulation of dephosphorylation GO:0035303 96 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
ribose phosphate biosynthetic process GO:0046390 82 0.025
cellular response to endogenous stimulus GO:0071495 336 0.025
cell cycle phase transition GO:0044770 173 0.025
regeneration GO:0031099 4 0.025
secretion GO:0046903 254 0.024
positive regulation of phosphorylation GO:0042327 394 0.024
negative regulation of apoptotic process GO:0043066 316 0.024
positive regulation of cell cycle process GO:0090068 106 0.024
regulation of nucleotide metabolic process GO:0006140 269 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.023
neuroblast proliferation GO:0007405 4 0.023
amine metabolic process GO:0009308 44 0.023
cellular component assembly involved in morphogenesis GO:0010927 73 0.023
regulation of nuclear division GO:0051783 65 0.023
regulation of cell morphogenesis GO:0022604 153 0.023
positive regulation of developmental process GO:0051094 314 0.023
cell part morphogenesis GO:0032990 137 0.023
positive regulation of cyclase activity GO:0031281 13 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
regulation of actin cytoskeleton organization GO:0032956 116 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
positive regulation of cellular component movement GO:0051272 181 0.022
spermatid development GO:0007286 4 0.022
regulation of protein kinase activity GO:0045859 289 0.022
response to abiotic stimulus GO:0009628 336 0.022
regulation of mitosis GO:0007088 63 0.022
organonitrogen compound biosynthetic process GO:1901566 200 0.022
regulation of adenylate cyclase activity GO:0045761 17 0.022
regulation of cell motility GO:2000145 299 0.021
cellular response to oxygen containing compound GO:1901701 276 0.021
chemotaxis GO:0006935 157 0.021
cellular amine metabolic process GO:0044106 41 0.021
centrosome separation GO:0051299 3 0.021
ribonucleotide catabolic process GO:0009261 405 0.021
negative regulation of phosphorylation GO:0042326 174 0.021
regulation of defense response GO:0031347 154 0.021
circulatory system development GO:0072359 262 0.021
regulation of cell projection organization GO:0031344 107 0.021
regulation of kinase activity GO:0043549 314 0.021
hemopoiesis GO:0030097 180 0.020
negative regulation of defense response GO:0031348 47 0.020
purine containing compound biosynthetic process GO:0072522 88 0.020
reproductive process GO:0022414 106 0.020
cardiac muscle contraction GO:0060048 34 0.020
divalent metal ion transport GO:0070838 152 0.020
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.020
negative regulation of cellular catabolic process GO:0031330 83 0.019
anatomical structure homeostasis GO:0060249 100 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.019
osteoblast differentiation GO:0001649 92 0.019
cation transmembrane transport GO:0098655 238 0.019
ribonucleoprotein complex assembly GO:0022618 78 0.019
regulation of locomotion GO:0040012 329 0.019
peripheral nervous system development GO:0007422 2 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
striated muscle contraction GO:0006941 52 0.019
immune response GO:0006955 307 0.019
cell aging GO:0007569 52 0.019
organelle fission GO:0048285 149 0.019
spermatid differentiation GO:0048515 4 0.019
regulation of immune response GO:0050776 201 0.018
rna splicing via transesterification reactions GO:0000375 90 0.018
oocyte development GO:0048599 1 0.018
determination of adult lifespan GO:0008340 2 0.018
regulation of mirna metabolic process GO:2000628 5 0.018
regulation of vasculature development GO:1901342 97 0.018
regulation of cell migration GO:0030334 289 0.018
nervous system development GO:0007399 293 0.018
blood vessel development GO:0001568 172 0.018
positive regulation of cell division GO:0051781 59 0.018
single organism reproductive process GO:0044702 98 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
regulation of gtp catabolic process GO:0033124 180 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
regulation of system process GO:0044057 101 0.018
wnt signaling pathway GO:0016055 156 0.018
regulation of cellular response to stress GO:0080135 244 0.017
compound eye development GO:0048749 1 0.017
positive regulation of ion transport GO:0043270 87 0.017
membrane raft localization GO:0051665 1 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
dna conformation change GO:0071103 113 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
centriole assembly GO:0098534 14 0.017
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.017
regulation of mapk cascade GO:0043408 262 0.017
defense response GO:0006952 315 0.017
regulation of protein ubiquitination GO:0031396 95 0.017
positive regulation of transport GO:0051050 336 0.017
intracellular protein transport GO:0006886 270 0.016
leukocyte differentiation GO:0002521 98 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
mitotic cell cycle process GO:1903047 286 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
positive regulation of gtp catabolic process GO:0033126 166 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
defense response to other organism GO:0098542 129 0.016
negative regulation of transferase activity GO:0051348 124 0.016
detection of stimulus GO:0051606 85 0.016
circulatory system process GO:0003013 113 0.016
transmembrane transport GO:0055085 399 0.016
dna repair GO:0006281 198 0.016
regulation of ras protein signal transduction GO:0046578 155 0.016
neural tube patterning GO:0021532 2 0.016
endomembrane system organization GO:0010256 196 0.016
tissue regeneration GO:0042246 3 0.016
cell cycle arrest GO:0007050 71 0.016
negative regulation of hydrolase activity GO:0051346 182 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
mitotic cell cycle GO:0000278 326 0.015
rna processing GO:0006396 255 0.015
regulation of meiosis GO:0040020 3 0.015
protein dephosphorylation GO:0006470 81 0.015
detection of calcium ion GO:0005513 8 0.015
cell fate determination GO:0001709 3 0.015
cellular homeostasis GO:0019725 196 0.015
regulation of striated muscle contraction GO:0006942 37 0.015
regulation of protein transport GO:0051223 213 0.015
dna replication GO:0006260 116 0.015
neural crest cell development GO:0014032 3 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
immune system development GO:0002520 195 0.015
response to bacterium GO:0009617 144 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
negative regulation of protein modification process GO:0031400 200 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
neurological system process GO:0050877 163 0.014
rna interference GO:0016246 4 0.014
cation homeostasis GO:0055080 189 0.014
positive regulation of cytoskeleton organization GO:0051495 83 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
segmentation GO:0035282 4 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
muscle system process GO:0003012 81 0.014
inorganic cation transmembrane transport GO:0098662 194 0.014
macromolecular complex disassembly GO:0032984 60 0.014
actin filament based process GO:0030029 224 0.014
skeletal system development GO:0001501 79 0.014
lipid metabolic process GO:0006629 381 0.014
response to nutrient levels GO:0031667 81 0.014
cell growth GO:0016049 160 0.014
single organism cellular localization GO:1902580 332 0.013
cellular lipid metabolic process GO:0044255 303 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
regulation of secretion GO:0051046 194 0.013
nucleoside catabolic process GO:0009164 408 0.013
regulation of heart rate GO:0002027 38 0.013
regulation of stress activated mapk cascade GO:0032872 84 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
neurogenesis GO:0022008 169 0.013
regulation of growth GO:0040008 165 0.013
regulation of gtpase activity GO:0043087 180 0.013
response to wounding GO:0009611 168 0.013
nucleotide catabolic process GO:0009166 408 0.013
blood vessel morphogenesis GO:0048514 162 0.013
protein processing GO:0016485 226 0.013
positive regulation of map kinase activity GO:0043406 80 0.013
camp metabolic process GO:0046058 61 0.013
developmental process involved in reproduction GO:0003006 66 0.013
sister chromatid segregation GO:0000819 54 0.013
stem cell division GO:0017145 2 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
negative regulation of developmental process GO:0051093 247 0.013
response to nitrogen compound GO:1901698 184 0.013
innate immune response GO:0045087 178 0.013
defense response to gram negative bacterium GO:0050829 14 0.013
response to organic cyclic compound GO:0014070 204 0.013
positive regulation of angiogenesis GO:0045766 51 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
activation of adenylate cyclase activity GO:0007190 5 0.012
central nervous system development GO:0007417 123 0.012
heart contraction GO:0060047 62 0.012
regulation of protein catabolic process GO:0042176 155 0.012
sensory perception GO:0007600 103 0.012
regulation of metal ion transport GO:0010959 120 0.012
positive regulation of ruffle assembly GO:1900029 4 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
response to radiation GO:0009314 151 0.012
protein heterotetramerization GO:0051290 3 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
mrna metabolic process GO:0016071 175 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
negative regulation of protein complex disassembly GO:0043242 20 0.012
cell cycle g2 m phase transition GO:0044839 43 0.012
jnk cascade GO:0007254 80 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
cell cell signaling GO:0007267 155 0.012
cellular component disassembly GO:0022411 92 0.012
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
response to extracellular stimulus GO:0009991 85 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
protein k63 linked deubiquitination GO:0070536 21 0.011
negative regulation of protein depolymerization GO:1901880 17 0.011
epithelial cell proliferation GO:0050673 128 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
regulation of phosphatase activity GO:0010921 81 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
receptor mediated endocytosis GO:0006898 84 0.011
actin mediated cell contraction GO:0070252 12 0.011
negative regulation of protein processing GO:0010955 142 0.011
ion transmembrane transport GO:0034220 338 0.011
head development GO:0060322 108 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
response to axon injury GO:0048678 1 0.011
actin filament based movement GO:0030048 17 0.011
regulation of transmembrane transport GO:0034762 139 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
memory GO:0007613 3 0.011
g1 s transition of mitotic cell cycle GO:0000082 78 0.011
cellular ion homeostasis GO:0006873 168 0.011
positive regulation of mirna metabolic process GO:2000630 4 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
negative regulation of wnt signaling pathway GO:0030178 69 0.011
rho protein signal transduction GO:0007266 26 0.010
system process GO:0003008 349 0.010
regulation of heart contraction GO:0008016 50 0.010
protein complex disassembly GO:0043241 52 0.010
regulation of rho gtpase activity GO:0032319 66 0.010
cerebellum development GO:0021549 2 0.010
sa node cell action potential GO:0086015 1 0.010
sex determination GO:0007530 3 0.010
protein tetramerization GO:0051262 47 0.010
positive regulation of mitosis GO:0045840 25 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.010
vasculature development GO:0001944 181 0.010
positive regulation of intracellular transport GO:0032388 104 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
ribonucleoside catabolic process GO:0042454 406 0.010
regulation of blood circulation GO:1903522 59 0.010
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010
regulation of binding GO:0051098 111 0.010
regulation of membrane potential GO:0042391 95 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010

CP110 disease predictions

Disease DO term ID Size Probability Func Analog Org
meckel syndrome DOID:0050778 11 0.868
joubert syndrome DOID:0050777 18 0.739
sensory system disease DOID:0050155 203 0.375
eye and adnexa disease DOID:1492 150 0.375
eye disease DOID:5614 149 0.375
nervous system disease DOID:863 431 0.375
retinal disease DOID:5679 118 0.085
heart conduction disease DOID:10273 18 0.051
cardiovascular system disease DOID:1287 106 0.051
brugada syndrome DOID:0050451 8 0.051
leber congenital amaurosis DOID:14791 16 0.024
central nervous system disease DOID:331 186 0.019
retinal degeneration DOID:8466 89 0.013
disease of metabolism DOID:0014667 295 0.010