Homo sapiens

70 known processes

CRYAB

crystallin, alpha B

(Aliases: CTPP2,HSPB5,CRYA2)

CRYAB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of light stimulus GO:0050953 35 1.000
Human
visual perception GO:0007601 27 1.000
Human
defense response to fungus GO:0050832 4 1.000
positive regulation of endothelial cell chemotaxis GO:2001028 5 0.999
negative regulation of cell death GO:0060548 345 0.982
protein homooligomerization GO:0051260 100 0.970
sensory perception GO:0007600 103 0.969
Human
response to fungus GO:0009620 4 0.968
cellular response to abiotic stimulus GO:0071214 117 0.967
negative regulation of apoptotic process GO:0043066 316 0.947
cellular response to ionizing radiation GO:0071479 32 0.947
response to temperature stimulus GO:0009266 22 0.943
Fly
negative regulation of programmed cell death GO:0043069 321 0.937
determination of adult lifespan GO:0008340 2 0.932
Fly
response to gamma radiation GO:0010332 14 0.927
system process GO:0003008 349 0.921
Human
response to radiation GO:0009314 151 0.918
cellular response to oxidative stress GO:0034599 85 0.908
regulation of intracellular transport GO:0032386 195 0.882
cellular response to radiation GO:0071478 65 0.862
positive regulation of cell migration by vascular endothelial growth factor signaling pathway GO:0038089 5 0.862
neurological system process GO:0050877 163 0.850
Human
regulation of endothelial cell chemotaxis GO:2001026 9 0.844
endothelial cell chemotaxis GO:0035767 13 0.828
coagulation GO:0050817 78 0.809
positive regulation of cell motility GO:2000147 177 0.805
response to abiotic stimulus GO:0009628 336 0.794
protein oligomerization GO:0051259 173 0.774
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.766
multicellular organismal aging GO:0010259 3 0.763
Fly
cell adhesion GO:0007155 325 0.763
cellular response to reactive oxygen species GO:0034614 50 0.759
enzyme linked receptor protein signaling pathway GO:0007167 303 0.755
endothelial cell migration GO:0043542 86 0.736
response to decreased oxygen levels GO:0036293 96 0.690
retina homeostasis GO:0001895 42 0.689
response to oxidative stress GO:0006979 121 0.684
Rat Fly
blood coagulation GO:0007596 76 0.682
tissue homeostasis GO:0001894 63 0.634
cell chemotaxis GO:0060326 112 0.624
response to wounding GO:0009611 168 0.621
regulation of cell motility GO:2000145 299 0.604
response to ionizing radiation GO:0010212 65 0.595
regulation of locomotion GO:0040012 329 0.589
response to heat GO:0009408 21 0.579
Fly
response to external biotic stimulus GO:0043207 261 0.564
regulation of chemotaxis GO:0050920 74 0.560
response to oxygen levels GO:0070482 100 0.556
negative regulation of transport GO:0051051 176 0.544
cellular response to gamma radiation GO:0071480 8 0.534
regulation of cellular component movement GO:0051270 334 0.534
blood vessel morphogenesis GO:0048514 162 0.523
cellular response to growth factor stimulus GO:0071363 197 0.518
ameboidal type cell migration GO:0001667 135 0.516
defense response to bacterium GO:0042742 63 0.515
regulation of muscle system process GO:0090257 53 0.515
regulation of epithelial cell migration GO:0010632 93 0.508
wound healing GO:0042060 115 0.502
angiogenesis GO:0001525 147 0.500
positive regulation of behavior GO:0048520 60 0.482
positive regulation of epithelial cell migration GO:0010634 55 0.477
regulation of cell migration GO:0030334 289 0.476
epithelial cell migration GO:0010631 119 0.473
cardiovascular system development GO:0072358 262 0.457
response to starvation GO:0042594 59 0.455
response to reactive oxygen species GO:0000302 61 0.448
Rat
negative regulation of intracellular transport GO:0032387 60 0.448
positive regulation of response to external stimulus GO:0032103 88 0.441
positive regulation of angiogenesis GO:0045766 51 0.436
biological adhesion GO:0022610 331 0.432
homotypic cell cell adhesion GO:0034109 47 0.411
positive regulation of chemotaxis GO:0050921 57 0.409
circulatory system development GO:0072359 262 0.406
vasculature development GO:0001944 181 0.405
regulation of protein kinase activity GO:0045859 289 0.397
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.396
blood vessel endothelial cell migration GO:0043534 42 0.393
positive regulation of cell migration GO:0030335 172 0.381
epithelium migration GO:0090132 119 0.377
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.370
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.357
cytokine production GO:0001816 247 0.346
response to hypoxia GO:0001666 96 0.333
defense response GO:0006952 315 0.328
cell type specific apoptotic process GO:0097285 125 0.309
taxis GO:0042330 157 0.305
cellular response to oxygen containing compound GO:1901701 276 0.305
response to biotic stimulus GO:0009607 276 0.304
regulation of vasculature development GO:1901342 97 0.293
blood vessel development GO:0001568 172 0.291
single organismal cell cell adhesion GO:0016337 148 0.289
anatomical structure homeostasis GO:0060249 100 0.284
defense response to other organism GO:0098542 129 0.282
chemotaxis GO:0006935 157 0.273
positive regulation of cellular component movement GO:0051272 181 0.273
negative regulation of cell proliferation GO:0008285 228 0.262
response to other organism GO:0051707 261 0.249
positive regulation of locomotion GO:0040017 186 0.242
cell activation GO:0001775 213 0.235
positive regulation of cellular amine metabolic process GO:0033240 7 0.223
negative regulation of phosphorus metabolic process GO:0010563 267 0.216
vascular endothelial growth factor signaling pathway GO:0038084 15 0.210
negative regulation of phosphate metabolic process GO:0045936 267 0.185
response to bacterium GO:0009617 144 0.179
regulation of apoptotic signaling pathway GO:2001233 175 0.178
regulation of angiogenesis GO:0045765 92 0.177
regulation of smooth muscle cell proliferation GO:0048660 28 0.176
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.176
apoptotic signaling pathway GO:0097190 268 0.168
small gtpase mediated signal transduction GO:0007264 78 0.167
response to nutrient levels GO:0031667 81 0.167
regulation of protein serine threonine kinase activity GO:0071900 179 0.161
regulation of cellular ketone metabolic process GO:0010565 50 0.161
response to virus GO:0009615 126 0.146
sulfur compound metabolic process GO:0006790 101 0.145
regulation of endothelial cell migration GO:0010594 67 0.139
platelet aggregation GO:0070527 32 0.138
tissue migration GO:0090130 119 0.133
behavior GO:0007610 112 0.130
regulation of anatomical structure morphogenesis GO:0022603 286 0.128
anatomical structure formation involved in morphogenesis GO:0048646 284 0.127
hemostasis GO:0007599 76 0.125
platelet activation GO:0030168 44 0.124
regulation of cellular amine metabolic process GO:0033238 11 0.122
positive regulation of endothelial cell migration GO:0010595 39 0.117
regulation of cellular response to oxidative stress GO:1900407 26 0.115
divalent metal ion transport GO:0070838 152 0.115
response to extracellular stimulus GO:0009991 85 0.113
regeneration GO:0031099 4 0.110
ras protein signal transduction GO:0007265 73 0.110
aging GO:0007568 66 0.109
Rat Fly
extrinsic apoptotic signaling pathway GO:0097191 119 0.107
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.104
purine ribonucleotide catabolic process GO:0009154 404 0.103
regulation of blood vessel endothelial cell migration GO:0043535 30 0.103
negative regulation of peptidase activity GO:0010466 91 0.102
negative regulation of apoptotic signaling pathway GO:2001234 97 0.102
positive regulation of immune system process GO:0002684 283 0.098
cytokine biosynthetic process GO:0042089 37 0.097
cellular lipid metabolic process GO:0044255 303 0.095
regulation of tumor necrosis factor biosynthetic process GO:0042534 8 0.095
cellular response to mechanical stimulus GO:0071260 39 0.092
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.090
regulation of ras protein signal transduction GO:0046578 155 0.088
regulation of oxidative stress induced cell death GO:1903201 24 0.087
actin mediated cell contraction GO:0070252 12 0.084
cellular response to external stimulus GO:0071496 111 0.081
multicellular organismal homeostasis GO:0048871 67 0.081
ribonucleotide catabolic process GO:0009261 405 0.081
negative regulation of cellular response to oxidative stress GO:1900408 18 0.081
response to growth factor GO:0070848 205 0.080
ion homeostasis GO:0050801 230 0.080
signal transduction by phosphorylation GO:0023014 297 0.079
Rat
amine metabolic process GO:0009308 44 0.077
regulation of cytoskeleton organization GO:0051493 177 0.077
negative regulation of protein metabolic process GO:0051248 391 0.077
nervous system development GO:0007399 293 0.077
single organism cell adhesion GO:0098602 179 0.077
negative regulation of catalytic activity GO:0043086 335 0.076
regulation of behavior GO:0050795 82 0.074
organophosphate biosynthetic process GO:0090407 163 0.073
positive regulation of keratinocyte proliferation GO:0010838 4 0.071
cellular ketone metabolic process GO:0042180 80 0.071
stress activated protein kinase signaling cascade GO:0031098 94 0.068
Rat
carbohydrate metabolic process GO:0005975 207 0.068
actin filament based movement GO:0030048 17 0.066
regulation of response to oxidative stress GO:1902882 26 0.065
negative regulation of cellular protein metabolic process GO:0032269 353 0.065
cardiac muscle cell contraction GO:0086003 4 0.065
regulation of muscle hypertrophy GO:0014743 10 0.065
positive regulation of transferase activity GO:0051347 227 0.065
regulation of actin filament based process GO:0032970 141 0.065
tissue morphogenesis GO:0048729 96 0.063
purine containing compound catabolic process GO:0072523 411 0.062
lipid metabolic process GO:0006629 381 0.062
immune response GO:0006955 307 0.061
ribonucleoside triphosphate metabolic process GO:0009199 412 0.060
cardiac muscle tissue development GO:0048738 39 0.060
glial cell migration GO:0008347 4 0.059
response to mechanical stimulus GO:0009612 51 0.059
ribonucleoside catabolic process GO:0042454 406 0.059
regulation of transferase activity GO:0051338 355 0.059
cellular response to dna damage stimulus GO:0006974 379 0.057
positive regulation of cell proliferation GO:0008284 301 0.057
positive regulation of developmental process GO:0051094 314 0.056
midbrain development GO:0030901 45 0.055
regulation of peptidase activity GO:0052547 180 0.054
negative regulation of oxidative stress induced cell death GO:1903202 17 0.054
regulation of response to external stimulus GO:0032101 222 0.053
reactive oxygen species metabolic process GO:0072593 75 0.053
Rat
regulation of synaptic plasticity GO:0048167 3 0.053
regulation of cellular amino acid metabolic process GO:0006521 6 0.053
regulation of cell development GO:0060284 161 0.052
intrinsic apoptotic signaling pathway GO:0097193 127 0.052
regulation of wnt signaling pathway GO:0030111 123 0.051
calcium mediated signaling GO:0019722 44 0.051
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.051
positive regulation of cell death GO:0010942 263 0.050
head development GO:0060322 108 0.050
cellular amine metabolic process GO:0044106 41 0.050
nucleoside catabolic process GO:0009164 408 0.050
response to organonitrogen compound GO:0010243 156 0.050
cofactor metabolic process GO:0051186 87 0.049
carbohydrate derivative biosynthetic process GO:1901137 207 0.048
nucleoside triphosphate catabolic process GO:0009143 394 0.048
actin cytoskeleton organization GO:0030036 207 0.047
cell death in response to oxidative stress GO:0036473 29 0.047
regulation of cysteine type endopeptidase activity GO:2000116 127 0.047
cellular response to tumor necrosis factor GO:0071356 63 0.046
protein import GO:0017038 130 0.046
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 5 0.045
epithelium development GO:0060429 227 0.045
negative regulation of protein modification process GO:0031400 200 0.045
protein maturation GO:0051604 233 0.045
peripheral nervous system development GO:0007422 2 0.044
cytoplasmic transport GO:0016482 379 0.044
protein processing GO:0016485 226 0.043
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.043
positive regulation of hydrolase activity GO:0051345 331 0.043
regulation of kinase activity GO:0043549 314 0.043
regulation of cellular response to stress GO:0080135 244 0.043
stress activated mapk cascade GO:0051403 93 0.042
Rat
positive regulation of cytokine production GO:0001819 167 0.042
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.042
oxidation reduction process GO:0055114 396 0.042
neural nucleus development GO:0048857 47 0.041
ribonucleoside monophosphate metabolic process GO:0009161 187 0.041
purine nucleoside monophosphate metabolic process GO:0009126 186 0.041
organonitrogen compound biosynthetic process GO:1901566 200 0.041
nucleocytoplasmic transport GO:0006913 176 0.040
regulation of cell adhesion GO:0030155 166 0.040
cell migration involved in gastrulation GO:0042074 1 0.039
negative regulation of intracellular signal transduction GO:1902532 183 0.039
muscle structure development GO:0061061 98 0.039
sequestering of calcium ion GO:0051208 17 0.039
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.038
sequestering of metal ion GO:0051238 24 0.038
single organism carbohydrate metabolic process GO:0044723 193 0.038
small molecule biosynthetic process GO:0044283 157 0.038
cellular amino acid metabolic process GO:0006520 116 0.038
regulation of establishment of protein localization GO:0070201 242 0.038
neuron projection regeneration GO:0031102 1 0.037
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.037
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.037
positive regulation of protein kinase activity GO:0045860 190 0.036
negative regulation of developmental process GO:0051093 247 0.036
positive regulation of programmed cell death GO:0043068 249 0.036
mapk cascade GO:0000165 288 0.036
Rat
negative regulation of cytokine production GO:0001818 82 0.036
epithelial cell proliferation GO:0050673 128 0.036
regulation of body fluid levels GO:0050878 99 0.035
posttranscriptional regulation of gene expression GO:0010608 213 0.035
brain development GO:0007420 97 0.035
regulation of anatomical structure size GO:0090066 101 0.035
protein localization to membrane GO:0072657 160 0.035
rho protein signal transduction GO:0007266 26 0.034
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.034
regulation of jnk cascade GO:0046328 73 0.034
cellular cation homeostasis GO:0030003 163 0.034
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.034
positive regulation of epithelial cell proliferation GO:0050679 65 0.034
i kappab kinase nf kappab signaling GO:0007249 166 0.034
establishment of protein localization to organelle GO:0072594 172 0.034
cellular macromolecular complex assembly GO:0034622 324 0.034
regulation of carbohydrate metabolic process GO:0006109 54 0.034
regulation of purine nucleotide catabolic process GO:0033121 205 0.034
positive regulation of cellular component organization GO:0051130 376 0.033
regulation of cell activation GO:0050865 125 0.033
ossification GO:0001503 121 0.033
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.033
locomotory behavior GO:0007626 1 0.033
actin filament organization GO:0007015 128 0.033
monocarboxylic acid metabolic process GO:0032787 185 0.032
negative regulation of protein maturation GO:1903318 142 0.032
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.032
regulation of defense response GO:0031347 154 0.032
regulation of protein processing GO:0070613 150 0.032
regulation of stress activated mapk cascade GO:0032872 84 0.031
regulation of cytokine production GO:0001817 232 0.031
eye development GO:0001654 42 0.031
cellular homeostasis GO:0019725 196 0.031
regulation of cytoplasmic transport GO:1903649 149 0.031
action potential GO:0001508 34 0.031
gtp catabolic process GO:0006184 237 0.031
positive regulation of protein phosphorylation GO:0001934 313 0.031
salivary gland morphogenesis GO:0007435 4 0.031
organic hydroxy compound metabolic process GO:1901615 147 0.031
negative regulation of hydrolase activity GO:0051346 182 0.031
positive regulation of interleukin 1 production GO:0032732 14 0.031
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.030
wnt signaling pathway GO:0016055 156 0.030
negative regulation of wnt signaling pathway GO:0030178 69 0.030
positive regulation of kinase activity GO:0033674 204 0.030
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.030
cellular response to organic cyclic compound GO:0071407 127 0.030
maintenance of location GO:0051235 112 0.030
cellular component morphogenesis GO:0032989 314 0.029
regulation of system process GO:0044057 101 0.029
neuroblast proliferation GO:0007405 4 0.029
positive regulation of mapk cascade GO:0043410 190 0.029
sulfur compound biosynthetic process GO:0044272 38 0.029
mitotic cell cycle process GO:1903047 286 0.029
glutathione metabolic process GO:0006749 20 0.029
camera type eye development GO:0043010 25 0.029
cardiac muscle cell cardiac muscle cell adhesion GO:0086042 1 0.029
nucleoside monophosphate metabolic process GO:0009123 191 0.028
coenzyme metabolic process GO:0006732 65 0.028
regulation of striated muscle contraction GO:0006942 37 0.028
pituitary gland development GO:0021983 2 0.028
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
positive regulation of phosphorylation GO:0042327 394 0.028
phospholipid metabolic process GO:0006644 99 0.028
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.028
circulatory system process GO:0003013 113 0.028
regulation of mapk cascade GO:0043408 262 0.028
regulation of cell growth GO:0001558 135 0.027
Rat
regulation of glial cell differentiation GO:0045685 3 0.027
regulation of glial cell proliferation GO:0060251 4 0.027
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 10 0.027
atp catabolic process GO:0006200 157 0.027
protein localization to organelle GO:0033365 280 0.026
lens development in camera type eye GO:0002088 2 0.026
cell morphogenesis GO:0000902 296 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
negative regulation of gliogenesis GO:0014014 3 0.026
regulation of epithelial cell proliferation GO:0050678 113 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.026
negative regulation of response to oxidative stress GO:1902883 18 0.026
cellular protein complex assembly GO:0043623 188 0.026
regulation of nucleoside metabolic process GO:0009118 209 0.026
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.026
actin filament based process GO:0030029 224 0.026
axis elongation GO:0003401 4 0.026
astrocyte differentiation GO:0048708 4 0.026
organophosphate catabolic process GO:0046434 430 0.026
cellular protein catabolic process GO:0044257 261 0.026
purine ribonucleoside catabolic process GO:0046130 398 0.026
cellular ion homeostasis GO:0006873 168 0.025
positive regulation of map kinase activity GO:0043406 80 0.025
organic hydroxy compound transport GO:0015850 63 0.025
cellular response to endogenous stimulus GO:0071495 336 0.025
regulation of proteolysis GO:0030162 293 0.025
mrna metabolic process GO:0016071 175 0.025
positive regulation of proteolysis GO:0045862 142 0.025
regulation of protein maturation GO:1903317 150 0.025
muscle organ development GO:0007517 56 0.024
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.024
regulation of protein localization GO:0032880 296 0.024
chromatin organization GO:0006325 351 0.024
regulation of endopeptidase activity GO:0052548 170 0.024
negative regulation of endopeptidase activity GO:0010951 84 0.024
nitrogen compound transport GO:0071705 191 0.024
regulation of small gtpase mediated signal transduction GO:0051056 156 0.024
muscle tissue development GO:0060537 62 0.024
positive regulation of dna metabolic process GO:0051054 73 0.024
regulation of metal ion transport GO:0010959 120 0.023
developmental programmed cell death GO:0010623 3 0.023
metal ion homeostasis GO:0055065 169 0.023
negative regulation of multicellular organismal process GO:0051241 317 0.023
response to axon injury GO:0048678 1 0.023
negative regulation of protein kinase activity GO:0006469 98 0.023
regulation of cytokine biosynthetic process GO:0042035 35 0.023
central nervous system development GO:0007417 123 0.023
regulation of protein transport GO:0051223 213 0.023
regulation of neural precursor cell proliferation GO:2000177 4 0.022
regulation of rho protein signal transduction GO:0035023 79 0.022
negative regulation of synaptic transmission GO:0050805 2 0.022
positive regulation of gtpase activity GO:0043547 166 0.022
membrane organization GO:0061024 292 0.022
stem cell division GO:0017145 2 0.022
glycerolipid metabolic process GO:0046486 107 0.022
nucleotide biosynthetic process GO:0009165 109 0.021
osteoblast differentiation GO:0001649 92 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
innate immune response GO:0045087 178 0.021
cellular metal ion homeostasis GO:0006875 146 0.021
negative regulation of proteolysis GO:0045861 132 0.021
canonical wnt signaling pathway GO:0060070 116 0.021
regulation of response to dna damage stimulus GO:2001020 94 0.021
positive regulation of neural precursor cell proliferation GO:2000179 2 0.021
cytokine metabolic process GO:0042107 38 0.021
regulation of cell differentiation GO:0045595 393 0.021
thymus development GO:0048538 3 0.021
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.021
negative regulation of blood pressure GO:0045776 3 0.021
striated muscle cell development GO:0055002 27 0.021
spermatid differentiation GO:0048515 4 0.021
positive regulation of organelle organization GO:0010638 195 0.020
growth GO:0040007 202 0.020
Rat
regulation of mitotic cell cycle GO:0007346 189 0.020
morphogenesis of embryonic epithelium GO:0016331 4 0.020
response to metal ion GO:0010038 84 0.020
vasodilation GO:0042311 4 0.020
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
protein stabilization GO:0050821 64 0.020
negative regulation of protein processing GO:0010955 142 0.020
positive regulation of protein kinase b signaling GO:0051897 42 0.020
focal adhesion assembly GO:0048041 30 0.020
activation of immune response GO:0002253 114 0.020
muscle cell differentiation GO:0042692 63 0.020
purine nucleotide biosynthetic process GO:0006164 84 0.020
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.020
cyclic nucleotide metabolic process GO:0009187 82 0.020
cell cycle checkpoint GO:0000075 117 0.020
response to caffeine GO:0031000 3 0.020
endomembrane system organization GO:0010256 196 0.020
epidermis morphogenesis GO:0048730 3 0.019
positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway GO:0038033 4 0.019
nuclear division GO:0000280 128 0.019
positive regulation of nucleotide catabolic process GO:0030813 185 0.019
plasma membrane organization GO:0007009 115 0.019
regulation of sensory perception of pain GO:0051930 3 0.019
regulation of ion transmembrane transport GO:0034765 132 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
embryonic epithelial tube formation GO:0001838 4 0.019
protein targeting GO:0006605 187 0.019
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.019
positive regulation of cell development GO:0010720 92 0.019
cholesterol metabolic process GO:0008203 28 0.019
regulation of cell cycle process GO:0010564 266 0.019
response to lipid GO:0033993 206 0.019
Rat
cellular response to glucocorticoid stimulus GO:0071385 4 0.019
jnk cascade GO:0007254 80 0.019
chromatin modification GO:0016568 298 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
peptidyl serine phosphorylation GO:0018105 101 0.019
positive regulation of tumor necrosis factor production GO:0032760 21 0.019
hair follicle morphogenesis GO:0031069 2 0.019
peptidyl tyrosine phosphorylation GO:0018108 170 0.019
organic hydroxy compound biosynthetic process GO:1901617 71 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
spinal cord development GO:0021510 4 0.018
positive regulation of interleukin 1 beta production GO:0032731 13 0.018
photoreceptor cell differentiation GO:0046530 2 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.018
regulation of dna metabolic process GO:0051052 153 0.018
regulation of reactive oxygen species metabolic process GO:2000377 41 0.018
Rat
cell cycle arrest GO:0007050 71 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
regulation of cell matrix adhesion GO:0001952 42 0.018
alcohol metabolic process GO:0006066 114 0.018
positive regulation of blood pressure GO:0045777 3 0.018
epithelial cell differentiation GO:0030855 141 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.018
protein targeting to nucleus GO:0044744 104 0.018
regulation of actin cytoskeleton organization GO:0032956 116 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
regulation of immune response GO:0050776 201 0.018
striated muscle tissue development GO:0014706 59 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
hindbrain development GO:0030902 3 0.017
cell junction assembly GO:0034329 67 0.017
regulation of binding GO:0051098 111 0.017
positive regulation of peptidase activity GO:0010952 88 0.017
positive regulation of cytokine biosynthetic process GO:0042108 25 0.017
response to oxygen containing compound GO:1901700 369 0.017
Rat
carbohydrate biosynthetic process GO:0016051 42 0.017
generation of precursor metabolites and energy GO:0006091 68 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
single organism cellular localization GO:1902580 332 0.017
leukocyte proliferation GO:0070661 74 0.017
regulation of protein stability GO:0031647 87 0.017
negative regulation of kinase activity GO:0033673 106 0.017

CRYAB disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.985
nervous system disease DOID:863 431 0.985
neuropathy DOID:870 52 0.985
Human
central nervous system disease DOID:331 186 0.889
Human
muscular disease DOID:0080000 114 0.754
heart disease DOID:114 68 0.754
cardiomyopathy DOID:0050700 50 0.754
myopathy DOID:423 104 0.754
cardiovascular system disease DOID:1287 106 0.754
muscle tissue disease DOID:66 113 0.754
neuromuscular disease DOID:440 38 0.698
Human
charcot marie tooth disease DOID:10595 33 0.663
Human
charcot marie tooth disease type 2 DOID:0050539 15 0.663
Human
motor neuritis DOID:683 5 0.344
Human
distal hereditary motor neuropathy DOID:0050582 5 0.344
Human
neurodegenerative disease DOID:1289 102 0.344
Human
motor neuron disease DOID:231 27 0.344
Human
intrinsic cardiomyopathy DOID:0060036 50 0.084
dilated cardiomyopathy DOID:12930 32 0.084
disease of metabolism DOID:0014667 295 0.036
disease of cellular proliferation DOID:14566 174 0.029
brain disease DOID:936 73 0.029
cancer DOID:162 167 0.024
organ system cancer DOID:0050686 164 0.022
disease by infectious agent DOID:0050117 34 0.018
sensory system disease DOID:0050155 203 0.017