|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.999
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.999
|
Human Mouse |
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.998
|
Human Mouse |
|
organ formation
|
GO:0048645 |
3 |
0.998
|
|
|
pancreatic a cell differentiation
|
GO:0003310 |
1 |
0.997
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.996
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.996
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.995
|
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.995
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.994
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.994
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.994
|
Human Mouse Fly |
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.993
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.992
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.990
|
|
|
heart field specification
|
GO:0003128 |
2 |
0.990
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.989
|
|
|
cardioblast cell fate specification
|
GO:0042685 |
1 |
0.985
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.985
|
Human Mouse |
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.985
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.983
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.980
|
|
|
negative regulation of heart induction by canonical wnt signaling pathway
|
GO:0003136 |
1 |
0.976
|
|
|
heart induction
|
GO:0003129 |
4 |
0.976
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.974
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.974
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.972
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.970
|
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.969
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.966
|
Mouse Fly |
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.965
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.959
|
Mouse Fly |
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.952
|
Mouse Fly |
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.951
|
Human Mouse |
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.948
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.940
|
Human |
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
0.938
|
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
2 |
0.936
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.930
|
|
|
negative regulation of cardioblast differentiation
|
GO:0051892 |
2 |
0.929
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.928
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.921
|
Mouse Fly |
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.920
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.916
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.910
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.906
|
Mouse Fly |
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.900
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.899
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.897
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.897
|
Mouse Fly |
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.896
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.891
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.887
|
Human |
|
cardiac cell fate specification
|
GO:0060912 |
1 |
0.883
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.883
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.880
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.874
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.872
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.870
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.864
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.861
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.860
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.851
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.839
|
Mouse Fly |
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.838
|
|
|
organ induction
|
GO:0001759 |
4 |
0.831
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.825
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.808
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.808
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.794
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.788
|
Fly |
|
cardioblast cell fate commitment
|
GO:0042684 |
1 |
0.788
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.784
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.778
|
Human Mouse |
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.776
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.767
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.766
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.764
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.753
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.751
|
Yeast |
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.745
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.739
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.737
|
Fly |
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.735
|
Mouse Fly |
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.717
|
Mouse Fly |
|
single organism cellular localization
|
GO:1902580 |
332 |
0.712
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.704
|
Fly |
|
cell development
|
GO:0048468 |
328 |
0.702
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.698
|
Mouse Fly |
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.687
|
Mouse Fly |
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.679
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.659
|
|
|
cochlea morphogenesis
|
GO:0090103 |
1 |
0.657
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.655
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.643
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.625
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.622
|
Mouse Fly |
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.619
|
Mouse Fly |
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.614
|
Human Yeast |
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.611
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.609
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.607
|
Mouse Fly |
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.607
|
Mouse Fly |
|
stem cell maintenance
|
GO:0019827 |
19 |
0.603
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.590
|
|
|
negative regulation of cardioblast cell fate specification
|
GO:0009997 |
1 |
0.587
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.579
|
Mouse Fly |
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.578
|
Mouse Fly |
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.570
|
Mouse Fly |
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.566
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.565
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.564
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.558
|
Fly |
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.553
|
|
|
non canonical wnt signaling pathway via jnk cascade
|
GO:0038031 |
3 |
0.547
|
|
|
wnt signaling pathway involved in heart development
|
GO:0003306 |
5 |
0.535
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.533
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.525
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.522
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.517
|
Mouse Fly |
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.498
|
|
|
negative regulation of heart induction
|
GO:1901320 |
1 |
0.497
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.494
|
Fly |
|
developmental induction
|
GO:0031128 |
5 |
0.491
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.488
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.485
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.484
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.480
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.477
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.477
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.475
|
Fly |
|
protein localization to organelle
|
GO:0033365 |
280 |
0.474
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.471
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.462
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.459
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.456
|
|
|
heart formation
|
GO:0060914 |
2 |
0.455
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.455
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.450
|
Mouse Fly |
|
female gamete generation
|
GO:0007292 |
2 |
0.443
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.442
|
Fly |
|
endoderm formation
|
GO:0001706 |
33 |
0.440
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.439
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.436
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.435
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.430
|
Worm Fly |
|
stem cell development
|
GO:0048864 |
69 |
0.426
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.421
|
|
|
embryo development
|
GO:0009790 |
123 |
0.412
|
Worm |
|
protein import
|
GO:0017038 |
130 |
0.398
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.395
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.394
|
Fly |
|
intracellular protein transport
|
GO:0006886 |
270 |
0.392
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.392
|
Mouse Fly |
|
chromatin modification
|
GO:0016568 |
298 |
0.390
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.389
|
Mouse |
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.388
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.387
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.368
|
|
|
establishment of apical basal cell polarity
|
GO:0035089 |
1 |
0.364
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.363
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.361
|
|
|
tube development
|
GO:0035295 |
125 |
0.355
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.351
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.348
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.347
|
Fly |
|
neuron fate commitment
|
GO:0048663 |
2 |
0.346
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.346
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.344
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.343
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.341
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.335
|
|
|
segmentation
|
GO:0035282 |
4 |
0.333
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.332
|
|
|
metanephric tubule morphogenesis
|
GO:0072173 |
1 |
0.328
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.327
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.321
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.311
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.311
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.308
|
Yeast |
|
endoderm development
|
GO:0007492 |
33 |
0.303
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.298
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.298
|
|
|
negative regulation of cardiac cell fate specification
|
GO:2000044 |
1 |
0.292
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.290
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.287
|
Fly |
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.286
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.283
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.279
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.278
|
|
|
cell growth
|
GO:0016049 |
160 |
0.276
|
Fly |
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.274
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.274
|
|
|
negative chemotaxis
|
GO:0050919 |
11 |
0.270
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.267
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.262
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.262
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.257
|
|
|
histone modification
|
GO:0016570 |
251 |
0.253
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.252
|
|
|
tube closure
|
GO:0060606 |
3 |
0.250
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.245
|
Human Yeast |
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.244
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.244
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.243
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.241
|
|
|
neural plate regionalization
|
GO:0060897 |
1 |
0.241
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.240
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.237
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.235
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.234
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.233
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.232
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.231
|
|
|
skin development
|
GO:0043588 |
76 |
0.231
|
Fly |
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.230
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.228
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.227
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.227
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.224
|
|
|
system process
|
GO:0003008 |
349 |
0.216
|
Fly |
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.215
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.214
|
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.214
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.212
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.212
|
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.210
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.210
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.208
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.207
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.204
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.203
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.203
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.203
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.202
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.202
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.202
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.201
|
|
|
ear development
|
GO:0043583 |
14 |
0.200
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.200
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.199
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.199
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.198
|
|
|
nerve development
|
GO:0021675 |
4 |
0.197
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.195
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.193
|
Fly |
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.193
|
Fly |
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.193
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.191
|
Fly |
|
signal transduction involved in regulation of gene expression
|
GO:0023019 |
1 |
0.190
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.188
|
Fly |
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.187
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.187
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.186
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.183
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.183
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.180
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.179
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.178
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.178
|
Fly |
|
nuclear transport
|
GO:0051169 |
179 |
0.177
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.177
|
Fly |
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.176
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.173
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.171
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.168
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.167
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.166
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.162
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.160
|
Fly |
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.159
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.157
|
Fly |
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.157
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.156
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.155
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.154
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.154
|
|
|
eye development
|
GO:0001654 |
42 |
0.154
|
Fly |
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.150
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.148
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.148
|
|
|
vesicle transport along microtubule
|
GO:0047496 |
4 |
0.148
|
|
|
regulation of cardioblast cell fate specification
|
GO:0042686 |
1 |
0.147
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.143
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.142
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.142
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.141
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.140
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.139
|
|
|
ear morphogenesis
|
GO:0042471 |
7 |
0.138
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.138
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.137
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.136
|
Fly |
|
protein targeting
|
GO:0006605 |
187 |
0.135
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.135
|
Fly |
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.135
|
Fly |
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.135
|
Yeast |
|
stem cell differentiation
|
GO:0048863 |
93 |
0.134
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.134
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.132
|
|
|
mechanosensory behavior
|
GO:0007638 |
4 |
0.130
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.130
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.130
|
Yeast |
|
sensory perception of sound
|
GO:0007605 |
37 |
0.129
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.129
|
Fly |
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.129
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.128
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.124
|
|
|
taxis
|
GO:0042330 |
157 |
0.123
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.122
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.122
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.122
|
Fly |
|
neurogenesis
|
GO:0022008 |
169 |
0.121
|
Fly |
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.120
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.120
|
Yeast |
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.119
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.119
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.119
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.117
|
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
5 |
0.117
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.116
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.115
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.114
|
Fly |
|
regulation of locomotion
|
GO:0040012 |
329 |
0.113
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.111
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.110
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.110
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.108
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.108
|
Mouse Fly |
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.107
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.107
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.107
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.105
|
|
|
hippo signaling
|
GO:0035329 |
20 |
0.104
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.104
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.103
|
Mouse Fly |
|
positive regulation of transport
|
GO:0051050 |
336 |
0.103
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.101
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.101
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.100
|
|
|
cardiac chamber formation
|
GO:0003207 |
2 |
0.100
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.099
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.099
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.099
|
|
|
establishment of epithelial cell polarity
|
GO:0090162 |
2 |
0.099
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.098
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.097
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.097
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.097
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.097
|
|
|
establishment or maintenance of monopolar cell polarity
|
GO:0061339 |
1 |
0.097
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.095
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.095
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.095
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.094
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.094
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.092
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.092
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.092
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.092
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.091
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.090
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.090
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.089
|
|
|
head development
|
GO:0060322 |
108 |
0.088
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.088
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.087
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.086
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.086
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.086
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.085
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.085
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
5 |
0.085
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.084
|
Yeast |
|
growth
|
GO:0040007 |
202 |
0.084
|
Worm Fly |
|
cell junction organization
|
GO:0034330 |
79 |
0.084
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.083
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.082
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.082
|
Fly |
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.081
|
|
|
heart development
|
GO:0007507 |
95 |
0.080
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.080
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.080
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.079
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.079
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
10 |
0.079
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.079
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.077
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.077
|
|
|
behavior
|
GO:0007610 |
112 |
0.076
|
Fly |
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
8 |
0.076
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.076
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.076
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.076
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.075
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.075
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.075
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.075
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.075
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.074
|
Fly |
|
nephron morphogenesis
|
GO:0072028 |
15 |
0.074
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.074
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.074
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.074
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.073
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.072
|
Fly |
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.072
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.072
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.072
|
|
|
brain development
|
GO:0007420 |
97 |
0.071
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.071
|
|
|
regionalization
|
GO:0003002 |
29 |
0.071
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.070
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.070
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.070
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.070
|
Yeast |
|
response to drug
|
GO:0042493 |
81 |
0.070
|
|
|
negative regulation of epidermal cell differentiation
|
GO:0045605 |
4 |
0.070
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.070
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.070
|
Fly |
|
neurological system process
|
GO:0050877 |
163 |
0.069
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.068
|
|
|
methylation
|
GO:0032259 |
106 |
0.068
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.068
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.066
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.066
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.066
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.065
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.064
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.064
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.064
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.063
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.063
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.063
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.063
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.062
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.062
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.062
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.061
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.061
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.060
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.060
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.060
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.060
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.060
|
Fly |
|
p38mapk cascade
|
GO:0038066 |
9 |
0.060
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.059
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.059
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.059
|
|
|
cardiac septum development
|
GO:0003279 |
13 |
0.059
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.059
|
|
|
reproduction
|
GO:0000003 |
63 |
0.058
|
Yeast Worm |
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.058
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.058
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.058
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.058
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.058
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.058
|
|
|
axon extension
|
GO:0048675 |
13 |
0.058
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.058
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.058
|
|
|
cell proliferation involved in heart morphogenesis
|
GO:0061323 |
1 |
0.058
|
|
|
regulation of sodium dependent phosphate transport
|
GO:2000118 |
2 |
0.057
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.056
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.055
|
Yeast |
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.055
|
|
|
trna wobble uridine modification
|
GO:0002098 |
3 |
0.055
|
Yeast |
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.055
|
|
|
gland development
|
GO:0048732 |
48 |
0.055
|
|
|
cell division
|
GO:0051301 |
168 |
0.054
|
Fly |
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.054
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.053
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.053
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.053
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.053
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.052
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.052
|
Fly |
|
axon development
|
GO:0061564 |
34 |
0.052
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.052
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.052
|
|