Homo sapiens

17 known processes

CSNK1E

casein kinase 1, epsilon

(Aliases: MGC10398,HCKIE)

CSNK1E biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
somatic stem cell maintenance GO:0035019 4 0.999
canonical wnt signaling pathway GO:0060070 116 0.999
Human Mouse
positive regulation of wnt signaling pathway GO:0030177 54 0.998
Human Mouse
organ formation GO:0048645 3 0.998
pancreatic a cell differentiation GO:0003310 1 0.997
negative regulation of cell fate specification GO:0009996 3 0.996
cardiac chamber morphogenesis GO:0003206 26 0.996
regulation of stress activated mapk cascade GO:0032872 84 0.995
regulation of heart induction GO:0090381 2 0.995
positive regulation of jnk cascade GO:0046330 52 0.994
stress activated protein kinase signaling cascade GO:0031098 94 0.994
wnt signaling pathway GO:0016055 156 0.994
Human Mouse Fly
negative regulation of cell fate commitment GO:0010454 3 0.993
jnk cascade GO:0007254 80 0.992
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.990
heart field specification GO:0003128 2 0.990
regulation of jnk cascade GO:0046328 73 0.989
cardioblast cell fate specification GO:0042685 1 0.985
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.985
Human Mouse
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.985
mapk cascade GO:0000165 288 0.983
regulation of jun kinase activity GO:0043506 27 0.980
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 1 0.976
heart induction GO:0003129 4 0.976
positive regulation of stress activated mapk cascade GO:0032874 60 0.974
regulation of mapk cascade GO:0043408 262 0.974
positive regulation of jun kinase activity GO:0043507 23 0.972
cardiovascular system development GO:0072358 262 0.970
regulation of organ formation GO:0003156 4 0.969
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.966
Mouse Fly
regulation of cardioblast differentiation GO:0051890 4 0.965
positive regulation of protein catabolic process GO:0045732 75 0.959
Mouse Fly
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.952
Mouse Fly
regulation of canonical wnt signaling pathway GO:0060828 88 0.951
Human Mouse
positive regulation of mapk cascade GO:0043410 190 0.948
positive regulation of phosphorylation GO:0042327 394 0.940
Human
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.938
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 2 0.936
morphogenesis of embryonic epithelium GO:0016331 4 0.930
negative regulation of cardioblast differentiation GO:0051892 2 0.929
regulation of protein serine threonine kinase activity GO:0071900 179 0.928
modification dependent protein catabolic process GO:0019941 209 0.921
Mouse Fly
regulation of map kinase activity GO:0043405 108 0.920
salivary gland morphogenesis GO:0007435 4 0.916
cell projection assembly GO:0030031 126 0.910
positive regulation of catabolic process GO:0009896 310 0.906
Mouse Fly
positive regulation of map kinase activity GO:0043406 80 0.900
regulation of heart morphogenesis GO:2000826 4 0.899
cell fate determination GO:0001709 3 0.897
cellular protein catabolic process GO:0044257 261 0.897
Mouse Fly
positive regulation of kinase activity GO:0033674 204 0.896
heart morphogenesis GO:0003007 48 0.891
positive regulation of protein phosphorylation GO:0001934 313 0.887
Human
cardiac cell fate specification GO:0060912 1 0.883
regulation of transferase activity GO:0051338 355 0.883
positive regulation of protein kinase activity GO:0045860 190 0.880
endodermal cell fate specification GO:0001714 4 0.874
positive regulation of transferase activity GO:0051347 227 0.872
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.870
formation of primary germ layer GO:0001704 42 0.864
non canonical wnt signaling pathway GO:0035567 14 0.861
cochlea development GO:0090102 1 0.860
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.851
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.839
Mouse Fly
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.838
organ induction GO:0001759 4 0.831
regulation of protein kinase activity GO:0045859 289 0.825
negative regulation of developmental process GO:0051093 247 0.808
retinal ganglion cell axon guidance GO:0031290 2 0.808
signal transduction by phosphorylation GO:0023014 297 0.794
nervous system development GO:0007399 293 0.788
Fly
cardioblast cell fate commitment GO:0042684 1 0.788
cellular component morphogenesis GO:0032989 314 0.784
regulation of wnt signaling pathway GO:0030111 123 0.778
Human Mouse
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.776
neural tube formation GO:0001841 3 0.767
negative regulation of multicellular organismal process GO:0051241 317 0.766
inner ear morphogenesis GO:0042472 4 0.764
regulation of kinase activity GO:0043549 314 0.753
vesicle mediated transport GO:0016192 371 0.751
Yeast
cell cell signaling involved in cell fate commitment GO:0045168 5 0.745
regulation of cellular response to stress GO:0080135 244 0.739
cell cell signaling GO:0007267 155 0.737
Fly
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.735
Mouse Fly
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.717
Mouse Fly
single organism cellular localization GO:1902580 332 0.712
epithelium development GO:0060429 227 0.704
Fly
cell development GO:0048468 328 0.702
regulation of proteasomal protein catabolic process GO:0061136 87 0.698
Mouse Fly
positive regulation of cellular protein catabolic process GO:1903364 37 0.687
Mouse Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.679
regulation of mitotic cell cycle GO:0007346 189 0.659
cochlea morphogenesis GO:0090103 1 0.657
stress activated mapk cascade GO:0051403 93 0.655
regulation of embryonic development GO:0045995 20 0.643
circulatory system development GO:0072359 262 0.625
modification dependent macromolecule catabolic process GO:0043632 212 0.622
Mouse Fly
regulation of proteolysis GO:0030162 293 0.619
Mouse Fly
microtubule cytoskeleton organization GO:0000226 176 0.614
Human Yeast
endodermal cell differentiation GO:0035987 31 0.611
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.609
positive regulation of proteolysis GO:0045862 142 0.607
Mouse Fly
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.607
Mouse Fly
stem cell maintenance GO:0019827 19 0.603
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.590
negative regulation of cardioblast cell fate specification GO:0009997 1 0.587
proteasomal protein catabolic process GO:0010498 176 0.579
Mouse Fly
positive regulation of cellular catabolic process GO:0031331 284 0.578
Mouse Fly
ubiquitin dependent protein catabolic process GO:0006511 206 0.570
Mouse Fly
actin cytoskeleton organization GO:0030036 207 0.566
regulation of anatomical structure morphogenesis GO:0022603 286 0.565
protein localization to nucleus GO:0034504 136 0.564
organ morphogenesis GO:0009887 147 0.558
Fly
embryonic epithelial tube formation GO:0001838 4 0.553
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.547
wnt signaling pathway involved in heart development GO:0003306 5 0.535
regulation of stem cell differentiation GO:2000736 56 0.533
regulation of cardiac cell fate specification GO:2000043 1 0.525
positive regulation of cellular amine metabolic process GO:0033240 7 0.522
regulation of cellular protein catabolic process GO:1903362 96 0.517
Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.498
negative regulation of heart induction GO:1901320 1 0.497
circadian behavior GO:0048512 2 0.494
Fly
developmental induction GO:0031128 5 0.491
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.488
activation of protein kinase activity GO:0032147 90 0.485
actin filament organization GO:0007015 128 0.484
positive regulation of cellular component organization GO:0051130 376 0.480
epidermis morphogenesis GO:0048730 3 0.477
regulation of protein localization GO:0032880 296 0.477
sensory organ development GO:0007423 52 0.475
Fly
protein localization to organelle GO:0033365 280 0.474
cell fate commitment involved in formation of primary germ layer GO:0060795 6 0.471
guanosine containing compound metabolic process GO:1901068 244 0.462
actin filament based process GO:0030029 224 0.459
regulation of binding GO:0051098 111 0.456
heart formation GO:0060914 2 0.455
rho protein signal transduction GO:0007266 26 0.455
cellular macromolecule catabolic process GO:0044265 380 0.450
Mouse Fly
female gamete generation GO:0007292 2 0.443
response to cocaine GO:0042220 1 0.442
Fly
endoderm formation GO:0001706 33 0.440
regulation of cytoskeleton organization GO:0051493 177 0.439
regulation of microtubule cytoskeleton organization GO:0070507 61 0.436
negative regulation of phosphorus metabolic process GO:0010563 267 0.435
post embryonic development GO:0009791 2 0.430
Worm Fly
stem cell development GO:0048864 69 0.426
negative regulation of phosphorylation GO:0042326 174 0.421
embryo development GO:0009790 123 0.412
Worm
protein import GO:0017038 130 0.398
histone acetylation GO:0016573 93 0.395
protein autophosphorylation GO:0046777 123 0.394
Fly
intracellular protein transport GO:0006886 270 0.392
regulation of protein catabolic process GO:0042176 155 0.392
Mouse Fly
chromatin modification GO:0016568 298 0.390
negative regulation of wnt signaling pathway GO:0030178 69 0.389
Mouse
internal peptidyl lysine acetylation GO:0018393 97 0.388
organelle localization GO:0051640 84 0.387
digestive tract development GO:0048565 75 0.368
establishment of apical basal cell polarity GO:0035089 1 0.364
regulation of cell fate specification GO:0042659 5 0.363
internal protein amino acid acetylation GO:0006475 101 0.361
tube development GO:0035295 125 0.355
neuron projection development GO:0031175 106 0.351
tube morphogenesis GO:0035239 95 0.348
establishment of tissue polarity GO:0007164 3 0.347
Fly
neuron fate commitment GO:0048663 2 0.346
single organism nuclear import GO:1902593 104 0.346
negative regulation of protein modification process GO:0031400 200 0.344
postsynaptic membrane organization GO:0001941 2 0.343
cell morphogenesis involved in differentiation GO:0000904 144 0.341
regulation of cell development GO:0060284 161 0.335
segmentation GO:0035282 4 0.333
gastrulation GO:0007369 51 0.332
metanephric tubule morphogenesis GO:0072173 1 0.328
peptidyl lysine acetylation GO:0018394 101 0.327
nucleoside phosphate catabolic process GO:1901292 412 0.321
cellular amino acid metabolic process GO:0006520 116 0.311
peptidyl lysine modification GO:0018205 144 0.311
meiotic chromosome segregation GO:0045132 4 0.308
Yeast
endoderm development GO:0007492 33 0.303
digestive tract morphogenesis GO:0048546 56 0.298
motor neuron axon guidance GO:0008045 2 0.298
negative regulation of cardiac cell fate specification GO:2000044 1 0.292
regulation of protein binding GO:0043393 66 0.290
sensory organ morphogenesis GO:0090596 21 0.287
Fly
negative regulation of cell proliferation GO:0008285 228 0.286
cell morphogenesis GO:0000902 296 0.283
embryonic skeletal joint development GO:0072498 2 0.279
regulation of cell motility GO:2000145 299 0.278
cell growth GO:0016049 160 0.276
Fly
ventricular septum morphogenesis GO:0060412 3 0.274
regulation of fat cell differentiation GO:0045598 23 0.274
negative chemotaxis GO:0050919 11 0.270
purine ribonucleoside metabolic process GO:0046128 437 0.267
positive regulation of nucleoside metabolic process GO:0045979 186 0.262
oogenesis GO:0048477 2 0.262
specification of organ identity GO:0010092 3 0.257
histone modification GO:0016570 251 0.253
protein targeting to nucleus GO:0044744 104 0.252
tube closure GO:0060606 3 0.250
microtubule based process GO:0007017 210 0.245
Human Yeast
small gtpase mediated signal transduction GO:0007264 78 0.244
negative regulation of cell differentiation GO:0045596 171 0.244
negative regulation of phosphate metabolic process GO:0045936 267 0.243
covalent chromatin modification GO:0016569 254 0.241
neural plate regionalization GO:0060897 1 0.241
endodermal cell fate commitment GO:0001711 4 0.240
chromatin organization GO:0006325 351 0.237
neuron projection morphogenesis GO:0048812 50 0.235
negative regulation of protein metabolic process GO:0051248 391 0.234
epithelial cell migration GO:0010631 119 0.233
eye photoreceptor cell differentiation GO:0001754 2 0.232
outflow tract septum morphogenesis GO:0003148 4 0.231
skin development GO:0043588 76 0.231
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.230
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.228
purine containing compound catabolic process GO:0072523 411 0.227
gtp catabolic process GO:0006184 237 0.227
regulation of epithelial cell migration GO:0010632 93 0.224
system process GO:0003008 349 0.216
Fly
regulation of epithelial cell proliferation GO:0050678 113 0.215
hindbrain development GO:0030902 3 0.214
establishment of monopolar cell polarity GO:0061162 1 0.214
negative regulation of glial cell proliferation GO:0060253 2 0.212
cardiocyte differentiation GO:0035051 23 0.212
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.210
negative regulation of protein kinase activity GO:0006469 98 0.210
negative regulation of epithelial cell migration GO:0010633 38 0.208
cardiac chamber development GO:0003205 30 0.207
convergent extension GO:0060026 1 0.204
nucleoside triphosphate metabolic process GO:0009141 422 0.203
regulation of cell migration GO:0030334 289 0.203
mesenchyme development GO:0060485 59 0.203
purine nucleoside triphosphate metabolic process GO:0009144 412 0.202
regulation of rho gtpase activity GO:0032319 66 0.202
protein acetylation GO:0006473 116 0.202
regulation of establishment of protein localization GO:0070201 242 0.201
ear development GO:0043583 14 0.200
regulation of cell morphogenesis GO:0022604 153 0.200
notch signaling pathway GO:0007219 31 0.199
positive regulation of nucleotide catabolic process GO:0030813 185 0.199
protein acylation GO:0043543 138 0.198
nerve development GO:0021675 4 0.197
cell fate commitment GO:0045165 27 0.195
secretion by cell GO:0032940 226 0.193
Fly
epithelial cell differentiation GO:0030855 141 0.193
Fly
regulation of actin cytoskeleton organization GO:0032956 116 0.193
morphogenesis of an epithelium GO:0002009 60 0.191
Fly
signal transduction involved in regulation of gene expression GO:0023019 1 0.190
negative regulation of cell death GO:0060548 345 0.188
Fly
i kappab kinase nf kappab signaling GO:0007249 166 0.187
lamellipodium organization GO:0097581 30 0.187
chordate embryonic development GO:0043009 34 0.186
negative regulation of mapk cascade GO:0043409 56 0.183
coenzyme metabolic process GO:0006732 65 0.183
regulation of cellular ketone metabolic process GO:0010565 50 0.180
cellular ketone metabolic process GO:0042180 80 0.179
ribonucleoside catabolic process GO:0042454 406 0.178
tissue morphogenesis GO:0048729 96 0.178
Fly
nuclear transport GO:0051169 179 0.177
response to organic cyclic compound GO:0014070 204 0.177
Fly
cell projection morphogenesis GO:0048858 129 0.176
forebrain regionalization GO:0021871 3 0.173
purine nucleotide catabolic process GO:0006195 405 0.171
regulation of glial cell proliferation GO:0060251 4 0.168
fat cell differentiation GO:0045444 32 0.167
ribonucleoside triphosphate metabolic process GO:0009199 412 0.166
regulation of cell fate commitment GO:0010453 7 0.162
response to oxygen containing compound GO:1901700 369 0.160
Fly
regulation of cell projection organization GO:0031344 107 0.159
regulation of cell growth GO:0001558 135 0.157
Fly
regulation of cell differentiation GO:0045595 393 0.157
regulation of cytoplasmic transport GO:1903649 149 0.156
negative regulation of transferase activity GO:0051348 124 0.155
embryonic organ morphogenesis GO:0048562 24 0.154
nucleoside triphosphate catabolic process GO:0009143 394 0.154
eye development GO:0001654 42 0.154
Fly
neuromuscular junction development GO:0007528 3 0.150
glycosyl compound catabolic process GO:1901658 413 0.148
negative regulation of growth GO:0045926 97 0.148
vesicle transport along microtubule GO:0047496 4 0.148
regulation of cardioblast cell fate specification GO:0042686 1 0.147
regulation of microtubule based process GO:0032886 74 0.143
skeletal system development GO:0001501 79 0.142
regulation of actin filament based process GO:0032970 141 0.142
activation of mapk activity GO:0000187 45 0.141
negative regulation of jnk cascade GO:0046329 16 0.140
regulation of response to external stimulus GO:0032101 222 0.139
ear morphogenesis GO:0042471 7 0.138
regulation of vesicle mediated transport GO:0060627 130 0.138
establishment of organelle localization GO:0051656 59 0.137
regulation of cell division GO:0051302 116 0.136
Fly
protein targeting GO:0006605 187 0.135
morphogenesis of a polarized epithelium GO:0001738 3 0.135
Fly
establishment of planar polarity GO:0001736 3 0.135
Fly
cytoplasmic transport GO:0016482 379 0.135
Yeast
stem cell differentiation GO:0048863 93 0.134
negative regulation of cell migration GO:0030336 102 0.134
negative regulation of protein phosphorylation GO:0001933 140 0.132
mechanosensory behavior GO:0007638 4 0.130
nucleotide catabolic process GO:0009166 408 0.130
meiosis i GO:0007127 4 0.130
Yeast
sensory perception of sound GO:0007605 37 0.129
neuron differentiation GO:0030182 138 0.129
Fly
regulation of cellular component biogenesis GO:0044087 281 0.129
positive regulation of rho protein signal transduction GO:0035025 4 0.128
axonogenesis GO:0007409 31 0.124
taxis GO:0042330 157 0.123
cellular amine metabolic process GO:0044106 41 0.122
positive regulation of gtp catabolic process GO:0033126 166 0.122
negative regulation of apoptotic process GO:0043066 316 0.122
Fly
neurogenesis GO:0022008 169 0.121
Fly
sulfur compound metabolic process GO:0006790 101 0.120
mitotic cell cycle GO:0000278 326 0.120
Yeast
cardiac septum morphogenesis GO:0060411 9 0.119
regulation of cellular amino acid metabolic process GO:0006521 6 0.119
regulation of cellular amine metabolic process GO:0033238 11 0.119
muscle structure development GO:0061061 98 0.117
regulation of establishment of planar polarity GO:0090175 5 0.117
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.116
nuclear import GO:0051170 106 0.115
positive regulation of cell division GO:0051781 59 0.114
Fly
regulation of locomotion GO:0040012 329 0.113
regulation of purine nucleotide catabolic process GO:0033121 205 0.111
amine metabolic process GO:0009308 44 0.110
anterior posterior axis specification GO:0009948 2 0.110
purine nucleoside catabolic process GO:0006152 398 0.108
protein catabolic process GO:0030163 325 0.108
Mouse Fly
regulation of nucleotide catabolic process GO:0030811 205 0.107
cell part morphogenesis GO:0032990 137 0.107
negative regulation of epithelial cell proliferation GO:0050680 48 0.107
guanosine containing compound catabolic process GO:1901069 239 0.105
hippo signaling GO:0035329 20 0.104
positive regulation of programmed cell death GO:0043068 249 0.104
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.103
Mouse Fly
positive regulation of transport GO:0051050 336 0.103
ameboidal type cell migration GO:0001667 135 0.101
spermatid development GO:0007286 4 0.101
activation of mapkk activity GO:0000186 18 0.100
cardiac chamber formation GO:0003207 2 0.100
negative regulation of intracellular signal transduction GO:1902532 183 0.099
primary neural tube formation GO:0014020 3 0.099
regulation of gtpase activity GO:0043087 180 0.099
establishment of epithelial cell polarity GO:0090162 2 0.099
neural tube closure GO:0001843 3 0.098
positive regulation of gtpase activity GO:0043547 166 0.097
epithelial cell proliferation GO:0050673 128 0.097
cofactor metabolic process GO:0051186 87 0.097
multi organism reproductive process GO:0044703 54 0.097
establishment or maintenance of monopolar cell polarity GO:0061339 1 0.097
pituitary gland development GO:0021983 2 0.095
endocytosis GO:0006897 159 0.095
positive regulation of hydrolase activity GO:0051345 331 0.095
neurotransmitter secretion GO:0007269 4 0.094
actin filament bundle organization GO:0061572 54 0.094
regulation of organ morphogenesis GO:2000027 24 0.092
negative regulation of catalytic activity GO:0043086 335 0.092
macromolecule deacylation GO:0098732 41 0.092
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.092
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.091
regulation of cell cycle process GO:0010564 266 0.090
peptidyl tyrosine modification GO:0018212 170 0.090
cellular protein complex assembly GO:0043623 188 0.089
head development GO:0060322 108 0.088
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.088
positive regulation of cell death GO:0010942 263 0.087
negative regulation of immune system process GO:0002683 136 0.086
cell adhesion GO:0007155 325 0.086
protein import into nucleus GO:0006606 104 0.086
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.085
smoothened signaling pathway GO:0007224 14 0.085
wnt signaling pathway planar cell polarity pathway GO:0060071 5 0.085
chromosome segregation GO:0007059 114 0.084
Yeast
growth GO:0040007 202 0.084
Worm Fly
cell junction organization GO:0034330 79 0.084
response to abiotic stimulus GO:0009628 336 0.083
protein polyubiquitination GO:0000209 110 0.082
generation of neurons GO:0048699 152 0.082
Fly
multicellular organism reproduction GO:0032504 42 0.081
heart development GO:0007507 95 0.080
regulation of ras gtpase activity GO:0032318 128 0.080
regulation of response to wounding GO:1903034 101 0.080
pattern specification process GO:0007389 43 0.079
cranial nerve development GO:0021545 4 0.079
outflow tract morphogenesis GO:0003151 10 0.079
positive regulation of protein kinase b signaling GO:0051897 42 0.079
regulation of nucleotide metabolic process GO:0006140 269 0.077
developmental process involved in reproduction GO:0003006 66 0.077
behavior GO:0007610 112 0.076
Fly
cell surface receptor signaling pathway involved in heart development GO:0061311 8 0.076
regulation of rho protein signal transduction GO:0035023 79 0.076
negative regulation of protein binding GO:0032091 35 0.076
genetic imprinting GO:0071514 1 0.076
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.075
g protein coupled receptor signaling pathway GO:0007186 207 0.075
negative regulation of cellular protein metabolic process GO:0032269 353 0.075
negative regulation of locomotion GO:0040013 118 0.075
epithelial tube morphogenesis GO:0060562 38 0.075
cell projection organization GO:0030030 252 0.074
Fly
nephron morphogenesis GO:0072028 15 0.074
positive regulation of nucleotide metabolic process GO:0045981 230 0.074
positive regulation of endocytosis GO:0045807 42 0.074
forebrain generation of neurons GO:0021872 3 0.074
regulation of chromosome organization GO:0033044 103 0.073
eye morphogenesis GO:0048592 16 0.072
Fly
nucleoside catabolic process GO:0009164 408 0.072
positive regulation of apoptotic process GO:0043065 246 0.072
somitogenesis GO:0001756 2 0.072
brain development GO:0007420 97 0.071
reproductive system development GO:0061458 56 0.071
regionalization GO:0003002 29 0.071
axis elongation GO:0003401 4 0.070
regulation of nucleoside metabolic process GO:0009118 209 0.070
regulation of gtp catabolic process GO:0033124 180 0.070
organelle fission GO:0048285 149 0.070
Yeast
response to drug GO:0042493 81 0.070
negative regulation of epidermal cell differentiation GO:0045605 4 0.070
cell fate specification GO:0001708 8 0.070
negative regulation of programmed cell death GO:0043069 321 0.070
Fly
neurological system process GO:0050877 163 0.069
peptidyl tyrosine phosphorylation GO:0018108 170 0.068
methylation GO:0032259 106 0.068
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.068
anterior posterior axis specification embryo GO:0008595 2 0.066
regulation of protein ubiquitination GO:0031396 95 0.066
regulation of protein targeting GO:1903533 91 0.066
cellular modified amino acid metabolic process GO:0006575 64 0.065
photoreceptor cell differentiation GO:0046530 2 0.064
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.064
mesenchymal cell differentiation GO:0048762 52 0.064
respiratory system development GO:0060541 22 0.063
establishment of protein localization to organelle GO:0072594 172 0.063
embryonic organ development GO:0048568 36 0.063
cilium assembly GO:0042384 63 0.063
regulation of apoptotic signaling pathway GO:2001233 175 0.062
organophosphate catabolic process GO:0046434 430 0.062
protein oligomerization GO:0051259 173 0.062
regulation of actin filament bundle assembly GO:0032231 36 0.061
positive regulation of neural precursor cell proliferation GO:2000179 2 0.061
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.060
gtp metabolic process GO:0046039 239 0.060
regulation of cytokine production GO:0001817 232 0.060
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.060
locomotory behavior GO:0007626 1 0.060
Fly
p38mapk cascade GO:0038066 9 0.060
ribonucleotide catabolic process GO:0009261 405 0.059
circadian sleep wake cycle process GO:0022410 2 0.059
regulation of cell cycle GO:0051726 393 0.059
cardiac septum development GO:0003279 13 0.059
regulation of protein processing GO:0070613 150 0.059
reproduction GO:0000003 63 0.058
Yeast Worm
regulation of protein kinase b signaling GO:0051896 61 0.058
protein kinase b signaling GO:0043491 69 0.058
regulation of protein complex assembly GO:0043254 147 0.058
spermatid differentiation GO:0048515 4 0.058
sensory perception GO:0007600 103 0.058
negative regulation of kinase activity GO:0033673 106 0.058
axon extension GO:0048675 13 0.058
negative regulation of smoothened signaling pathway GO:0045879 3 0.058
protein ubiquitination GO:0016567 314 0.058
cell proliferation involved in heart morphogenesis GO:0061323 1 0.058
regulation of sodium dependent phosphate transport GO:2000118 2 0.057
digestive system development GO:0055123 75 0.056
mitotic cell cycle process GO:1903047 286 0.055
Yeast
negative regulation of cell development GO:0010721 48 0.055
trna wobble uridine modification GO:0002098 3 0.055
Yeast
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.055
gland development GO:0048732 48 0.055
cell division GO:0051301 168 0.054
Fly
regulation of ras protein signal transduction GO:0046578 155 0.054
nucleocytoplasmic transport GO:0006913 176 0.053
protein homooligomerization GO:0051260 100 0.053
purine nucleoside triphosphate catabolic process GO:0009146 392 0.053
developmental cell growth GO:0048588 18 0.053
positive regulation of cell cycle GO:0045787 140 0.052
regulation of hormone levels GO:0010817 125 0.052
Fly
axon development GO:0061564 34 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.052
ribonucleoside triphosphate catabolic process GO:0009203 391 0.052

CSNK1E disease predictions

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 52 0.693
organ system cancer DOID:0050686 164 0.693
disease of cellular proliferation DOID:14566 174 0.693
cancer DOID:162 167 0.693
gastrointestinal system disease DOID:77 36 0.291
mouth disease DOID:403 14 0.291
tooth disease DOID:1091 14 0.291
teeth hard tissue disease DOID:214 8 0.291
dental enamel hypoplasia DOID:693 7 0.103
amelogenesis imperfecta DOID:2187 7 0.103
intestinal cancer DOID:10155 29 0.100
large intestine cancer DOID:5672 29 0.100
colon cancer DOID:219 25 0.100
colorectal cancer DOID:9256 29 0.100