|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
regulation of gastrulation
|
GO:0010470 |
12 |
0.877
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.854
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.830
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.793
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.708
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.686
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.653
|
|
|
|
negative regulation of peptidyl lysine acetylation
|
GO:2000757 |
8 |
0.648
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.631
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.630
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.621
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.611
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.597
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.586
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.582
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.542
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.529
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.512
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.490
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.488
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.482
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.476
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.469
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.461
|
|
|
|
regulation of protein acetylation
|
GO:1901983 |
25 |
0.457
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.446
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.436
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.427
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.404
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.403
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.396
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.395
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.395
|
|
|
|
negative regulation of protein acetylation
|
GO:1901984 |
11 |
0.385
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.385
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.373
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.371
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.359
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.357
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.349
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.341
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.340
|
|
|
|
regulation of hemoglobin biosynthetic process
|
GO:0046984 |
1 |
0.335
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.317
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.316
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.311
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.300
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.297
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.293
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.291
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.283
|
Fly |
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.270
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.264
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.255
|
|
|
|
cell cell adhesion involved in gastrulation
|
GO:0070586 |
6 |
0.254
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.250
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.250
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.249
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.247
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.246
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.243
|
|
|
|
regulation of smooth muscle cell differentiation
|
GO:0051150 |
3 |
0.242
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.242
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.239
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.239
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.237
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.235
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.231
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.230
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.229
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.228
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.223
|
|
|
|
regulation of cell cell adhesion involved in gastrulation
|
GO:0070587 |
6 |
0.219
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.212
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.211
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.210
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.209
|
Fly |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.209
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.208
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.202
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.195
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.181
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.179
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.178
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.178
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.175
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.173
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.169
|
|
|
|
negative regulation of histone acetylation
|
GO:0035067 |
6 |
0.168
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.167
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.166
|
Fly |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.163
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.163
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.162
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.160
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.157
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.155
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.155
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.152
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.148
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.147
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.145
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.142
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.141
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.141
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.140
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.137
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.137
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.136
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.134
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.134
|
Human |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.131
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.130
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.129
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.126
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.123
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.123
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.121
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.119
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.116
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.115
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.109
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.109
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.108
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.108
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.107
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.107
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.104
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.103
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.101
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.100
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.099
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.096
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.094
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.093
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.092
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.092
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.090
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.090
|
Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.089
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.089
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.088
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.088
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.088
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.088
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.087
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.086
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.086
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.085
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.085
|
|
|
|
natural killer cell differentiation
|
GO:0001779 |
2 |
0.083
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.082
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.082
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.081
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.081
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.080
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.080
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.078
|
|
|
|
regulation of granulocyte differentiation
|
GO:0030852 |
11 |
0.078
|
|
|
|
hemoglobin biosynthetic process
|
GO:0042541 |
3 |
0.078
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.077
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.077
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.077
|
Fly |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.076
|
|
|
|
chemokine c x c motif ligand 2 production
|
GO:0072567 |
3 |
0.076
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.075
|
|
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.075
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.073
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.073
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.073
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
15 |
0.072
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.071
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.071
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.071
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.069
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.069
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.069
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.069
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.068
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.068
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.068
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.068
|
|
|
|
natural killer cell activation
|
GO:0030101 |
12 |
0.067
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.067
|
|
|
|
brain morphogenesis
|
GO:0048854 |
1 |
0.067
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.067
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.067
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.066
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.066
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.066
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.066
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.065
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.065
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.065
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.062
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.062
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.062
|
|
|
|
pigmentation
|
GO:0043473 |
22 |
0.061
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.061
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.059
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.058
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.058
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.056
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.056
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.056
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.056
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.056
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.056
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.055
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.055
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.055
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.054
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.054
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.054
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.054
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.053
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.053
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.053
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.053
|
|
|
|
negative regulation of histone modification
|
GO:0031057 |
19 |
0.053
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.053
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.052
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.052
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.051
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.051
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.051
|
|
|
|
regulation of retinoic acid receptor signaling pathway
|
GO:0048385 |
9 |
0.051
|
Human |
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.051
|
Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.051
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.050
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.050
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.050
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.049
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.048
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.048
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.047
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.047
|
|
|
|
neuronal ion channel clustering
|
GO:0045161 |
2 |
0.047
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.047
|
|
|
|
negative regulation of smooth muscle cell proliferation
|
GO:0048662 |
14 |
0.047
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.046
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.046
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.046
|
|
|
|
b cell differentiation
|
GO:0030183 |
6 |
0.046
|
|
|
|
growth
|
GO:0040007 |
202 |
0.046
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.045
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.045
|
|
|
|
head development
|
GO:0060322 |
108 |
0.045
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.045
|
|
|
|
negative regulation of interleukin 8 biosynthetic process
|
GO:0045415 |
3 |
0.045
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.044
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
17 |
0.044
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.044
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.044
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.044
|
|
|
|
regulation of chemokine c x c motif ligand 2 production
|
GO:2000341 |
2 |
0.043
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.043
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.042
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.042
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
12 |
0.042
|
|
|
|
cellular response to laminar fluid shear stress
|
GO:0071499 |
5 |
0.042
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.041
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.040
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.040
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.040
|
Fly |
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.040
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.038
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.038
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.038
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.038
|
|
|
|
semicircular canal morphogenesis
|
GO:0048752 |
1 |
0.038
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.038
|
|
|
|
hemoglobin metabolic process
|
GO:0020027 |
3 |
0.038
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.037
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.037
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.037
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.037
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.037
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.036
|
Rat |
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.036
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.036
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.036
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.036
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
5 |
0.036
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.036
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.036
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
5 |
0.036
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.036
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.036
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.036
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.035
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.035
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.035
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.035
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.035
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.035
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.034
|
Fly |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.034
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.034
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.034
|
|
|
|
stem cell proliferation
|
GO:0072089 |
25 |
0.034
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.033
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.033
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.033
|
|
|
|
post embryonic hemopoiesis
|
GO:0035166 |
1 |
0.033
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.033
|
|
|
|
system process
|
GO:0003008 |
349 |
0.033
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.033
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.033
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.032
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.032
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.032
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.032
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
2 |
0.032
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.032
|
Fly |
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.031
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.031
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.031
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.031
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.030
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.030
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.030
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.030
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.030
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.030
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.030
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.030
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.029
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.029
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.029
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.029
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.029
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.029
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.029
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.029
|
|
|
|
negative regulation of retinoic acid receptor signaling pathway
|
GO:0048387 |
4 |
0.029
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.029
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.029
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.029
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.029
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.028
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.028
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.028
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.027
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.027
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.027
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.027
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.027
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.027
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.027
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.027
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.027
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.027
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.026
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.026
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.026
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.026
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.026
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.026
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.026
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.025
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.025
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.025
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.025
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.025
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.025
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.025
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.024
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.024
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.024
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.024
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.024
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.024
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.024
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
13 |
0.024
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.024
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.024
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.024
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.024
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.024
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.023
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.023
|
|
|
|
dna demethylation
|
GO:0080111 |
12 |
0.023
|
|
|
|
positive regulation of nitric oxide biosynthetic process
|
GO:0045429 |
13 |
0.023
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.023
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.023
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.023
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.023
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.022
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.022
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.022
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.022
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
20 |
0.022
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.022
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.022
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.022
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.022
|
|
|
|
negative regulation of chemokine c x c motif ligand 2 production
|
GO:2000342 |
1 |
0.021
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.021
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.021
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.021
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.021
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.021
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.021
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.021
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.021
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.021
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.021
|
|
|
|
muscle adaptation
|
GO:0043500 |
12 |
0.021
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.020
|
Fly |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.020
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.020
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.020
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.020
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.020
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.020
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.020
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.020
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
21 |
0.020
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.020
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.020
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.019
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.019
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.019
|
|
|
|
regulation of viral release from host cell
|
GO:1902186 |
20 |
0.019
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.019
|
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
9 |
0.019
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.019
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.019
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.019
|
|
|
|
cochlea morphogenesis
|
GO:0090103 |
1 |
0.019
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.019
|
|
|
|
atp dependent chromatin remodeling
|
GO:0043044 |
25 |
0.018
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.018
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.018
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.018
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.018
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.018
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.018
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.018
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.018
|
|
|
|
positive regulation of histone deacetylation
|
GO:0031065 |
6 |
0.018
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.018
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.018
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.018
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.018
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.018
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.018
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.018
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.017
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.017
|
|
|
|
double strand break repair via single strand annealing
|
GO:0045002 |
4 |
0.017
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.017
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.017
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.017
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.017
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.017
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.017
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.016
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.016
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.016
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.016
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.016
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.016
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.016
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.016
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.016
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.016
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.016
|
|
|
|
developmental pigmentation
|
GO:0048066 |
12 |
0.016
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.016
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.016
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.015
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.015
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.015
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.015
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.015
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.015
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.015
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.015
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.015
|
|
