Homo sapiens

91 known processes

CXXC1

CXXC finger protein 1

(Aliases: 5830420C16Rik,CFP1,HsT2645,PHF18,2410002I16Rik,CGBP,ZCGPC1,SPP1,hCGBP,PCCX1)

CXXC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 298 0.990
chromatin organization GO:0006325 351 0.985
macromolecule methylation GO:0043414 97 0.979
histone lysine methylation GO:0034968 50 0.978
covalent chromatin modification GO:0016569 254 0.951
histone modification GO:0016570 251 0.940
histone methylation GO:0016571 60 0.916
cellular ketone metabolic process GO:0042180 80 0.773
histone h3 k4 methylation GO:0051568 27 0.738
cellular response to dna damage stimulus GO:0006974 379 0.651
methylation GO:0032259 106 0.573
protein acetylation GO:0006473 116 0.559
protein methylation GO:0006479 74 0.472
regulation of cellular amine metabolic process GO:0033238 11 0.461
protein alkylation GO:0008213 74 0.447
transdifferentiation GO:0060290 2 0.442
Worm
histone h4 k8 acetylation GO:0043982 15 0.440
cellular amino acid metabolic process GO:0006520 116 0.403
amine metabolic process GO:0009308 44 0.331
regulation of cellular ketone metabolic process GO:0010565 50 0.254
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.253
protein acylation GO:0043543 138 0.234
negative regulation of cell cycle GO:0045786 193 0.216
regulation of cellular amino acid metabolic process GO:0006521 6 0.200
regulation of cell cycle GO:0051726 393 0.188
negative regulation of catalytic activity GO:0043086 335 0.173
peptidyl lysine acetylation GO:0018394 101 0.157
regulation of response to dna damage stimulus GO:2001020 94 0.156
post embryonic development GO:0009791 2 0.147
Worm
cellular amine metabolic process GO:0044106 41 0.143
negative regulation of cellular protein metabolic process GO:0032269 353 0.142
negative regulation of protein metabolic process GO:0051248 391 0.139
peptidyl lysine modification GO:0018205 144 0.132
determination of adult lifespan GO:0008340 2 0.116
multicellular organismal aging GO:0010259 3 0.112
nervous system development GO:0007399 293 0.110
negative regulation of phosphorus metabolic process GO:0010563 267 0.108
regulation of transferase activity GO:0051338 355 0.103
cell development GO:0048468 328 0.097
rna 3 end processing GO:0031123 35 0.092
positive regulation of chromosome organization GO:2001252 41 0.083
female gamete generation GO:0007292 2 0.079
response to abiotic stimulus GO:0009628 336 0.075
positive regulation of cellular component organization GO:0051130 376 0.075
positive regulation of cell death GO:0010942 263 0.074
protein ubiquitination GO:0016567 314 0.074
single organism carbohydrate metabolic process GO:0044723 193 0.073
regulation of protein kinase activity GO:0045859 289 0.073
regulation of cellular response to growth factor stimulus GO:0090287 76 0.073
negative regulation of protein modification process GO:0031400 200 0.073
compound eye development GO:0048749 1 0.072
internal protein amino acid acetylation GO:0006475 101 0.072
regulation of chromosome organization GO:0033044 103 0.072
negative regulation of phosphate metabolic process GO:0045936 267 0.068
rna processing GO:0006396 255 0.068
signal transduction by phosphorylation GO:0023014 297 0.066
regulation of mapk cascade GO:0043408 262 0.065
internal peptidyl lysine acetylation GO:0018393 97 0.065
segmentation GO:0035282 4 0.064
oocyte differentiation GO:0009994 2 0.064
embryo development GO:0009790 123 0.064
growth GO:0040007 202 0.062
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.061
peptidyl lysine dimethylation GO:0018027 3 0.061
dna replication GO:0006260 116 0.061
protein processing GO:0016485 226 0.060
oocyte development GO:0048599 1 0.059
positive regulation of organelle organization GO:0010638 195 0.055
negative regulation of cell cycle process GO:0010948 121 0.055
protein modification by small protein conjugation GO:0032446 342 0.055
ncrna processing GO:0034470 83 0.054
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.054
response to lipid GO:0033993 206 0.053
regulation of dna metabolic process GO:0051052 153 0.052
anatomical structure homeostasis GO:0060249 100 0.051
response to hormone GO:0009725 175 0.049
positive regulation of programmed cell death GO:0043068 249 0.049
neurogenesis GO:0022008 169 0.047
response to radiation GO:0009314 151 0.046
organelle fission GO:0048285 149 0.046
mitotic cell cycle GO:0000278 326 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.046
regulation of peptidase activity GO:0052547 180 0.045
vesicle mediated transport GO:0016192 371 0.045
cellular macromolecular complex assembly GO:0034622 324 0.044
positive regulation of hydrolase activity GO:0051345 331 0.044
single organism membrane organization GO:0044802 268 0.043
response to other organism GO:0051707 261 0.043
cell projection organization GO:0030030 252 0.043
regulation of cysteine type endopeptidase activity GO:2000116 127 0.043
regulation of cellular response to stress GO:0080135 244 0.043
histone h3 k4 trimethylation GO:0080182 7 0.042
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.042
mrna metabolic process GO:0016071 175 0.041
interspecies interaction between organisms GO:0044419 156 0.041
dna biosynthetic process GO:0071897 40 0.041
positive regulation of chromatin modification GO:1903310 30 0.039
chromosome segregation GO:0007059 114 0.039
cell cycle checkpoint GO:0000075 117 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
negative regulation of protein processing GO:0010955 142 0.038
regulation of kinase activity GO:0043549 314 0.038
response to external biotic stimulus GO:0043207 261 0.038
regulation of endopeptidase activity GO:0052548 170 0.037
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.037
protein catabolic process GO:0030163 325 0.037
response to biotic stimulus GO:0009607 276 0.037
embryo development ending in birth or egg hatching GO:0009792 34 0.036
membrane organization GO:0061024 292 0.036
modification dependent protein catabolic process GO:0019941 209 0.035
cellular response to organic cyclic compound GO:0071407 127 0.035
histone h4 k16 acetylation GO:0043984 14 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.035
regulation of cell cycle phase transition GO:1901987 126 0.035
cellular homeostasis GO:0019725 196 0.035
response to growth factor GO:0070848 205 0.035
regulation of cell division GO:0051302 116 0.034
apoptotic signaling pathway GO:0097190 268 0.034
reproduction GO:0000003 63 0.034
negative regulation of phosphorylation GO:0042326 174 0.034
positive regulation of histone modification GO:0031058 29 0.033
meiotic chromosome segregation GO:0045132 4 0.033
enzyme linked receptor protein signaling pathway GO:0007167 303 0.033
viral process GO:0016032 146 0.033
negative regulation of cellular amine metabolic process GO:0033239 3 0.033
positive regulation of proteolysis GO:0045862 142 0.033
single organism cellular localization GO:1902580 332 0.033
peptidyl lysine methylation GO:0018022 37 0.032
cellular response to endogenous stimulus GO:0071495 336 0.032
cell division GO:0051301 168 0.032
response to ionizing radiation GO:0010212 65 0.032
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.032
proteasomal protein catabolic process GO:0010498 176 0.031
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.030
cellular component morphogenesis GO:0032989 314 0.030
negative regulation of multicellular organismal process GO:0051241 317 0.030
Worm
blastoderm segmentation GO:0007350 2 0.029
positive regulation of apoptotic process GO:0043065 246 0.029
carbohydrate metabolic process GO:0005975 207 0.029
cellular protein catabolic process GO:0044257 261 0.028
defense response GO:0006952 315 0.028
positive regulation of peptidase activity GO:0010952 88 0.028
negative regulation of developmental process GO:0051093 247 0.028
Worm
anterior posterior axis specification GO:0009948 2 0.027
negative regulation of cell death GO:0060548 345 0.027
regulation of growth GO:0040008 165 0.027
cell morphogenesis involved in differentiation GO:0000904 144 0.027
cellular macromolecule catabolic process GO:0044265 380 0.026
negative regulation of cell cycle phase transition GO:1901988 89 0.026
negative regulation of hydrolase activity GO:0051346 182 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.026
glucose metabolic process GO:0006006 45 0.026
oogenesis GO:0048477 2 0.026
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.026
transcription from rna polymerase iii promoter GO:0006383 19 0.026
cellular response to growth factor stimulus GO:0071363 197 0.025
stress activated mapk cascade GO:0051403 93 0.025
cell cycle phase transition GO:0044770 173 0.025
protein polyubiquitination GO:0000209 110 0.025
positive regulation of transferase activity GO:0051347 227 0.025
regulation of mitotic cell cycle GO:0007346 189 0.025
central nervous system projection neuron axonogenesis GO:0021952 3 0.025
negative regulation of cellular component organization GO:0051129 235 0.025
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.024
histone h4 k5 acetylation GO:0043981 15 0.024
single organism reproductive process GO:0044702 98 0.024
positive regulation of endopeptidase activity GO:0010950 84 0.024
regulation of jnk cascade GO:0046328 73 0.024
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.024
reproductive process GO:0022414 106 0.024
negative regulation of mitotic cell cycle GO:0045930 102 0.024
regulation of gene expression epigenetic GO:0040029 73 0.024
Zebrafish
negative regulation of programmed cell death GO:0043069 321 0.024
negative regulation of multi organism process GO:0043901 92 0.024
negative regulation of mapk cascade GO:0043409 56 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
endocytosis GO:0006897 159 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.023
central nervous system development GO:0007417 123 0.022
mitotic nuclear division GO:0007067 119 0.022
negative regulation of transferase activity GO:0051348 124 0.022
regulation of multi organism process GO:0043900 157 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
purine ribonucleoside metabolic process GO:0046128 437 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.022
response to uv GO:0009411 73 0.021
histone acetylation GO:0016573 93 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
negative regulation of protein kinase activity GO:0006469 98 0.021
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.021
regulation of intracellular transport GO:0032386 195 0.021
negative regulation of growth GO:0045926 97 0.021
dephosphorylation GO:0016311 209 0.021
regulation of protein stability GO:0031647 87 0.021
regulation of histone modification GO:0031056 47 0.021
negative regulation of apoptotic process GO:0043066 316 0.020
ncrna metabolic process GO:0034660 108 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
regulation of cellular protein catabolic process GO:1903362 96 0.020
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
mitotic cell cycle process GO:1903047 286 0.020
multi organism cellular process GO:0044764 156 0.020
positive regulation of catabolic process GO:0009896 310 0.020
endomembrane system organization GO:0010256 196 0.019
cellular response to abiotic stimulus GO:0071214 117 0.019
regulation of protein processing GO:0070613 150 0.019
regulation of cell cycle process GO:0010564 266 0.019
generation of neurons GO:0048699 152 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
convergent extension GO:0060026 1 0.019
regulation of protein catabolic process GO:0042176 155 0.019
regulation of binding GO:0051098 111 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.018
regulation of dna replication GO:0006275 68 0.018
innate immune response GO:0045087 178 0.018
negative regulation of phosphatase activity GO:0010923 61 0.018
regulation of response to biotic stimulus GO:0002831 55 0.018
immune response GO:0006955 307 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
cell projection morphogenesis GO:0048858 129 0.017
regulation of stress activated mapk cascade GO:0032872 84 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.017
regulation of protein acetylation GO:1901983 25 0.017
regulation of glucose metabolic process GO:0010906 28 0.017
negative regulation of gene expression epigenetic GO:0045814 19 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
negative regulation of kinase activity GO:0033673 106 0.017
negative regulation of apoptotic signaling pathway GO:2001234 97 0.017
regulation of dna repair GO:0006282 47 0.017
regulation of proteolysis GO:0030162 293 0.016
histone h4 acetylation GO:0043967 47 0.016
response to oxygen containing compound GO:1901700 369 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
regulation of secretion by cell GO:1903530 177 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
neuron differentiation GO:0030182 138 0.016
cellular protein complex assembly GO:0043623 188 0.016
defense response to other organism GO:0098542 129 0.016
establishment of protein localization to membrane GO:0090150 121 0.016
cell morphogenesis GO:0000902 296 0.016
receptor mediated endocytosis GO:0006898 84 0.015
secretion by cell GO:0032940 226 0.015
immune effector process GO:0002252 159 0.015
positive regulation of transport GO:0051050 336 0.015
positive regulation of immune response GO:0050778 159 0.015
regulation of protein transport GO:0051223 213 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
central nervous system neuron axonogenesis GO:0021955 3 0.015
negative regulation of cytokine production GO:0001818 82 0.015
regulation of protein complex assembly GO:0043254 147 0.015
protein modification by small protein removal GO:0070646 92 0.015
response to nitrogen compound GO:1901698 184 0.015
dna methylation or demethylation GO:0044728 19 0.015
Zebrafish
protein maturation GO:0051604 233 0.014
gene silencing GO:0016458 49 0.014
cellular response to nitrogen compound GO:1901699 144 0.014
regulation of cell differentiation GO:0045595 393 0.014
response to inorganic substance GO:0010035 127 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.014
developmental growth GO:0048589 48 0.014
mitochondrion organization GO:0007005 156 0.014
positive regulation of protein binding GO:0032092 24 0.014
regulation of protein localization GO:0032880 296 0.014
positive regulation of protein catabolic process GO:0045732 75 0.014
regulation of immune response GO:0050776 201 0.014
viral life cycle GO:0019058 132 0.014
protein localization to membrane GO:0072657 160 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
response to organic cyclic compound GO:0014070 204 0.013
aging GO:0007568 66 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
regulation of chromatin organization GO:1902275 56 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
regulation of chromatin modification GO:1903308 51 0.013
regulation of defense response GO:0031347 154 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
regulation of protein maturation GO:1903317 150 0.013
developmental process involved in reproduction GO:0003006 66 0.013
positive regulation of binding GO:0051099 45 0.013
purine containing compound catabolic process GO:0072523 411 0.012
regulation of histone acetylation GO:0035065 19 0.012
positive regulation of dna metabolic process GO:0051054 73 0.012
brain development GO:0007420 97 0.012
dna damage checkpoint GO:0000077 68 0.012
nucleotide excision repair GO:0006289 31 0.012
intracellular protein transport GO:0006886 270 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
atp metabolic process GO:0046034 176 0.012
response to transforming growth factor beta GO:0071559 94 0.012
nucleotide catabolic process GO:0009166 408 0.012
negative regulation of protein maturation GO:1903318 142 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
ameboidal type cell migration GO:0001667 135 0.012
embryonic organ development GO:0048568 36 0.012
regulation of secretion GO:0051046 194 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
golgi vesicle transport GO:0048193 80 0.012
ribonucleoside catabolic process GO:0042454 406 0.011
negative regulation of proteolysis GO:0045861 132 0.011
dna templated transcription initiation GO:0006352 35 0.011
dna repair GO:0006281 198 0.011
regulation of mitosis GO:0007088 63 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
immune system development GO:0002520 195 0.011
Zebrafish
response to decreased oxygen levels GO:0036293 96 0.011
organophosphate catabolic process GO:0046434 430 0.011
system process GO:0003008 349 0.011
embryonic organ morphogenesis GO:0048562 24 0.011
multi organism reproductive process GO:0044703 54 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
cell part morphogenesis GO:0032990 137 0.011
neural tube formation GO:0001841 3 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
sex differentiation GO:0007548 45 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.011
chromatin remodeling GO:0006338 55 0.011
regulation of dna biosynthetic process GO:2000278 18 0.011
viral latency GO:0019042 1 0.011
spermatid development GO:0007286 4 0.011
jnk cascade GO:0007254 80 0.011
dna integrity checkpoint GO:0031570 71 0.011
neuromuscular junction development GO:0007528 3 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
spermatid differentiation GO:0048515 4 0.010
negative regulation of stress activated mapk cascade GO:0032873 19 0.010
embryonic morphogenesis GO:0048598 85 0.010
hexose metabolic process GO:0019318 55 0.010
hindbrain development GO:0030902 3 0.010
intracellular mrna localization GO:0008298 1 0.010
autophagy GO:0006914 88 0.010
ribonucleoside triphosphate catabolic process GO:0009203 391 0.010
regulation of autophagy GO:0010506 52 0.010
negative regulation of response to external stimulus GO:0032102 83 0.010
cell activation GO:0001775 213 0.010

CXXC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.025
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.012
central nervous system disease DOID:331 186 0.012
nervous system disease DOID:863 431 0.012