Homo sapiens

43 known processes

CYP2A6

cytochrome P450, family 2, subfamily A, polypeptide 6

(Aliases: CYP2A3,CYP2A,CPA6,P450C2A,P450PB)

CYP2A6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phenylpropanoid metabolic process GO:0009698 3 1.000
naphthalene metabolic process GO:0018931 1 1.000
negative regulation of cellular organofluorine metabolic process GO:0090350 1 1.000
cellular organohalogen metabolic process GO:0090345 2 1.000
isoquinoline alkaloid metabolic process GO:0033076 1 1.000
negative regulation of cellular organohalogen metabolic process GO:0090349 1 1.000
epoxygenase p450 pathway GO:0019373 3 1.000
oxidative demethylation GO:0070989 11 1.000
naphthalene containing compound metabolic process GO:0090420 1 1.000
regulation of cellular organofluorine metabolic process GO:0090348 1 1.000
coumarin metabolic process GO:0009804 2 1.000
regulation of cellular organohalogen metabolic process GO:0090347 1 1.000
cellular organofluorine metabolic process GO:0090346 2 1.000
drug catabolic process GO:0042737 10 1.000
nitrogen cycle metabolic process GO:0071941 3 1.000
alkaloid metabolic process GO:0009820 4 1.000
long chain fatty acid metabolic process GO:0001676 30 0.999
urea metabolic process GO:0019627 3 0.998
alkaloid catabolic process GO:0009822 3 0.998
arachidonic acid metabolic process GO:0019369 14 0.996
monoterpenoid metabolic process GO:0016098 6 0.994
terpenoid metabolic process GO:0006721 27 0.953
linoleic acid metabolic process GO:0043651 4 0.946
steroid metabolic process GO:0008202 94 0.940
demethylation GO:0070988 37 0.925
response to xenobiotic stimulus GO:0009410 30 0.887
xenobiotic metabolic process GO:0006805 28 0.841
drug metabolic process GO:0017144 19 0.797
exogenous drug catabolic process GO:0042738 8 0.788
oxidation reduction process GO:0055114 396 0.728
monocarboxylic acid metabolic process GO:0032787 185 0.724
lipid metabolic process GO:0006629 381 0.717
cellular response to xenobiotic stimulus GO:0071466 29 0.695
icosanoid metabolic process GO:0006690 35 0.664
cellular ketone metabolic process GO:0042180 80 0.649
fatty acid derivative metabolic process GO:1901568 35 0.590
unsaturated fatty acid metabolic process GO:0033559 37 0.579
isoprenoid metabolic process GO:0006720 39 0.495
response to phenylpropanoid GO:0080184 1 0.361
secondary metabolic process GO:0019748 17 0.292
organic hydroxy compound metabolic process GO:1901615 147 0.288
cofactor metabolic process GO:0051186 87 0.261
response to organic cyclic compound GO:0014070 204 0.259
fatty acid metabolic process GO:0006631 115 0.255
cellular lipid metabolic process GO:0044255 303 0.250
regulation of hormone levels GO:0010817 125 0.215
response to metal ion GO:0010038 84 0.208
negative regulation of binding GO:0051100 57 0.198
g protein coupled receptor signaling pathway GO:0007186 207 0.153
response to oxygen containing compound GO:1901700 369 0.139
response to inorganic substance GO:0010035 127 0.125
regulation of binding GO:0051098 111 0.124
response to drug GO:0042493 81 0.123
response to hormone GO:0009725 175 0.121
chemical homeostasis GO:0048878 306 0.114
cellular response to endogenous stimulus GO:0071495 336 0.101
cellular amide metabolic process GO:0043603 69 0.100
anion transport GO:0006820 161 0.092
protein activation cascade GO:0072376 22 0.091
regulation of response to wounding GO:1903034 101 0.089
regulation of cellular ketone metabolic process GO:0010565 50 0.088
response to nitrogen compound GO:1901698 184 0.083
response to organonitrogen compound GO:0010243 156 0.078
positive regulation of immune system process GO:0002684 283 0.078
negative regulation of apoptotic process GO:0043066 316 0.075
leukotriene b4 metabolic process GO:0036102 2 0.075
cellular amino acid metabolic process GO:0006520 116 0.073
camp biosynthetic process GO:0006171 47 0.071
negative regulation of wound healing GO:0061045 25 0.068
thyroid hormone transport GO:0070327 2 0.067
cellular response to metal ion GO:0071248 43 0.067
cellular response to oxygen containing compound GO:1901701 276 0.061
carboxylic acid catabolic process GO:0046395 71 0.060
nucleotide biosynthetic process GO:0009165 109 0.059
negative regulation of response to external stimulus GO:0032102 83 0.059
immune response GO:0006955 307 0.059
pyruvate family amino acid catabolic process GO:0009080 3 0.057
post embryonic development GO:0009791 2 0.056
regulation of secretion GO:0051046 194 0.056
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
camp metabolic process GO:0046058 61 0.053
organonitrogen compound biosynthetic process GO:1901566 200 0.053
cellular homeostasis GO:0019725 196 0.053
negative regulation of response to wounding GO:1903035 47 0.053
heme metabolic process GO:0042168 8 0.052
regulation of body fluid levels GO:0050878 99 0.051
negative regulation of developmental process GO:0051093 247 0.050
protein processing GO:0016485 226 0.049
determination of adult lifespan GO:0008340 2 0.048
negative regulation of catalytic activity GO:0043086 335 0.046
negative regulation of cellular protein metabolic process GO:0032269 353 0.046
regulation of response to external stimulus GO:0032101 222 0.045
response to lipid GO:0033993 206 0.044
regulation of locomotion GO:0040012 329 0.044
acute inflammatory response GO:0002526 21 0.043
innate immune response GO:0045087 178 0.043
system process GO:0003008 349 0.043
response to wounding GO:0009611 168 0.042
blood coagulation GO:0007596 76 0.042
multicellular organismal aging GO:0010259 3 0.041
urate metabolic process GO:0046415 11 0.040
cellular cation homeostasis GO:0030003 163 0.040
vitamin k catabolic process GO:0042377 2 0.039
cellular amine metabolic process GO:0044106 41 0.039
negative regulation of phosphate metabolic process GO:0045936 267 0.038
cyclic nucleotide biosynthetic process GO:0009190 61 0.038
inflammatory response GO:0006954 79 0.038
negative regulation of protein metabolic process GO:0051248 391 0.038
organic acid transport GO:0015849 65 0.037
water homeostasis GO:0030104 14 0.037
nitrogen compound transport GO:0071705 191 0.037
single organism carbohydrate metabolic process GO:0044723 193 0.036
cellular response to inorganic substance GO:0071241 45 0.036
carbohydrate derivative biosynthetic process GO:1901137 207 0.036
negative regulation of hemostasis GO:1900047 22 0.035
defense response GO:0006952 315 0.035
regeneration GO:0031099 4 0.034
enzyme linked receptor protein signaling pathway GO:0007167 303 0.034
organic acid catabolic process GO:0016054 71 0.034
urate transport GO:0015747 3 0.034
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
cardiovascular system development GO:0072358 262 0.033
cellular response to organic cyclic compound GO:0071407 127 0.033
regulation of camp biosynthetic process GO:0030817 45 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
lipid catabolic process GO:0016042 84 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.031
ion homeostasis GO:0050801 230 0.031
protein maturation GO:0051604 233 0.030
nucleoside triphosphate metabolic process GO:0009141 422 0.030
organic anion transport GO:0015711 103 0.030
carbohydrate metabolic process GO:0005975 207 0.030
epithelial cell differentiation GO:0030855 141 0.030
positive regulation of secretion by cell GO:1903532 108 0.029
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.029
interspecies interaction between organisms GO:0044419 156 0.029
regulation of cellular component movement GO:0051270 334 0.028
organophosphate biosynthetic process GO:0090407 163 0.028
negative regulation of cell migration GO:0030336 102 0.028
regulation of wound healing GO:0061041 56 0.028
tetrapyrrole metabolic process GO:0033013 11 0.028
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.027
positive regulation of phosphorylation GO:0042327 394 0.027
regulation of cyclase activity GO:0031279 19 0.027
alpha amino acid metabolic process GO:1901605 72 0.027
negative regulation of voltage gated calcium channel activity GO:1901386 4 0.027
positive regulation of synaptic transmission GO:0050806 4 0.027
regulation of reactive oxygen species metabolic process GO:2000377 41 0.027
positive regulation of camp biosynthetic process GO:0030819 35 0.027
cyclic purine nucleotide metabolic process GO:0052652 60 0.027
positive regulation of immune response GO:0050778 159 0.027
regulation of cell differentiation GO:0045595 393 0.026
regulation of cell cycle GO:0051726 393 0.026
sodium ion transport GO:0006814 61 0.026
vitamin catabolic process GO:0009111 6 0.026
secretion by cell GO:0032940 226 0.026
blood circulation GO:0008015 113 0.026
negative regulation of cell death GO:0060548 345 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.025
regulation of kinase activity GO:0043549 314 0.025
long term memory GO:0007616 2 0.024
cellular response to organonitrogen compound GO:0071417 124 0.024
interspecies quorum sensing GO:0052097 1 0.024
female gamete generation GO:0007292 2 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
cellular response to disaccharide stimulus GO:0071324 1 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.024
positive regulation of mapk cascade GO:0043410 190 0.024
ribonucleotide biosynthetic process GO:0009260 81 0.024
positive regulation of homeostatic process GO:0032846 47 0.024
immune effector process GO:0002252 159 0.023
purine containing compound biosynthetic process GO:0072522 88 0.023
growth GO:0040007 202 0.023
synaptic transmission GO:0007268 61 0.023
positive regulation of transport GO:0051050 336 0.023
reactive oxygen species metabolic process GO:0072593 75 0.023
negative regulation of synaptic transmission GO:0050805 2 0.023
regulation of cell motility GO:2000145 299 0.023
regulation of cell migration GO:0030334 289 0.023
organic hydroxy compound biosynthetic process GO:1901617 71 0.023
regulation of mapk cascade GO:0043408 262 0.023
organ morphogenesis GO:0009887 147 0.023
alcohol metabolic process GO:0006066 114 0.023
regulation of homeostatic process GO:0032844 121 0.023
activation of immune response GO:0002253 114 0.022
negative regulation of blood coagulation GO:0030195 22 0.022
carnitine transmembrane transport GO:1902603 3 0.022
amide transport GO:0042886 76 0.022
amine metabolic process GO:0009308 44 0.022
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.022
regulation of secretion by cell GO:1903530 177 0.022
limbic system development GO:0021761 3 0.022
short chain fatty acid import GO:0015913 1 0.022
icosanoid catabolic process GO:1901523 2 0.022
cellular ion homeostasis GO:0006873 168 0.021
hematopoietic or lymphoid organ development GO:0048534 186 0.021
cellular hormone metabolic process GO:0034754 41 0.021
purine nucleotide biosynthetic process GO:0006164 84 0.021
small molecule biosynthetic process GO:0044283 157 0.021
leukotriene catabolic process GO:0036100 2 0.021
cyclic nucleotide metabolic process GO:0009187 82 0.021
porphyrin containing compound metabolic process GO:0006778 10 0.021
regulation of immune response GO:0050776 201 0.020
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 3 0.020
epithelium development GO:0060429 227 0.020
regulation of lyase activity GO:0051339 23 0.020
mapk cascade GO:0000165 288 0.020
positive regulation of developmental process GO:0051094 314 0.020
cell substrate adhesion GO:0031589 132 0.020
cell cell signaling GO:0007267 155 0.020
response to axon injury GO:0048678 1 0.020
regulation of protein kinase activity GO:0045859 289 0.020
regulation of protein transport GO:0051223 213 0.020
reactive oxygen species biosynthetic process GO:1903409 4 0.020
vitamin e metabolic process GO:0042360 1 0.020
pyruvate family amino acid metabolic process GO:0009078 4 0.020
regulation of proteolysis GO:0030162 293 0.019
response to camp GO:0051591 25 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
negative regulation of blood pressure GO:0045776 3 0.019
cellular response to nitrogen compound GO:1901699 144 0.019
response to calcium ion GO:0051592 46 0.019
positive regulation of cellular component movement GO:0051272 181 0.019
vesicle mediated transport GO:0016192 371 0.019
positive regulation of protein transport GO:0051222 135 0.019
phylloquinone metabolic process GO:0042374 2 0.019
cation homeostasis GO:0055080 189 0.019
regulation of defense response GO:0031347 154 0.019
positive regulation of cell migration GO:0030335 172 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
single organism cellular localization GO:1902580 332 0.019
positive regulation of secretion GO:0051047 116 0.019
carboxylic acid transport GO:0046942 63 0.018
oogenesis GO:0048477 2 0.018
cellular response to hormone stimulus GO:0032870 125 0.018
cation transport GO:0006812 331 0.018
cellular response to cytokine stimulus GO:0071345 181 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
response to glucagon GO:0033762 1 0.018
dephosphorylation GO:0016311 209 0.018
vasculature development GO:0001944 181 0.018
cell adhesion GO:0007155 325 0.018
negative regulation of locomotion GO:0040013 118 0.018
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.018
regulation of protein localization GO:0032880 296 0.018
regulation of metal ion transport GO:0010959 120 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
renal tubular secretion GO:0097254 1 0.017
secretion GO:0046903 254 0.017
regulation of camp metabolic process GO:0030814 52 0.017
maintenance of location GO:0051235 112 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
biological adhesion GO:0022610 331 0.017
regulation of protein processing GO:0070613 150 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
regulation of transferase activity GO:0051338 355 0.017
purine ribonucleoside metabolic process GO:0046128 437 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
epithelial cell proliferation GO:0050673 128 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
response to organophosphorus GO:0046683 41 0.017
receptor internalization GO:0031623 43 0.017
alanine metabolic process GO:0006522 4 0.017
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.017
visual behavior GO:0007632 2 0.017
regulation of peptide hormone secretion GO:0090276 41 0.017
regulation of coagulation GO:0050818 44 0.017
purine ribonucleotide biosynthetic process GO:0009152 79 0.017
cell morphogenesis GO:0000902 296 0.016
metal ion transport GO:0030001 272 0.016
organophosphate catabolic process GO:0046434 430 0.016
negative regulation of cell differentiation GO:0045596 171 0.016
positive regulation of transferase activity GO:0051347 227 0.016
negative regulation of programmed cell death GO:0043069 321 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
regulation of protein secretion GO:0050708 86 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
ribose phosphate biosynthetic process GO:0046390 82 0.016
cell projection assembly GO:0030031 126 0.016
response to extracellular stimulus GO:0009991 85 0.016
regulation of cell adhesion GO:0030155 166 0.016
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.016
negative regulation of immune system process GO:0002683 136 0.015
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.015
sodium ion transmembrane transport GO:0035725 59 0.015
protein ubiquitination GO:0016567 314 0.015
immune system development GO:0002520 195 0.015
cytokine production GO:0001816 247 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
alpha ketoglutarate transport GO:0015742 1 0.015
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.015
negative regulation of cell cycle GO:0045786 193 0.015
phospholipase c activating dopamine receptor signaling pathway GO:0060158 2 0.015
cytoplasmic transport GO:0016482 379 0.015
regulation of erk1 and erk2 cascade GO:0070372 99 0.015
negative regulation of protein maturation GO:1903318 142 0.015
apoptotic signaling pathway GO:0097190 268 0.015
cellular chemical homeostasis GO:0055082 180 0.015
negative regulation of protein processing GO:0010955 142 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
protein catabolic process GO:0030163 325 0.015
response to abiotic stimulus GO:0009628 336 0.015
receptor metabolic process GO:0043112 81 0.015
positive regulation of catabolic process GO:0009896 310 0.015
cation transmembrane transport GO:0098655 238 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
ion transmembrane transport GO:0034220 338 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.014
protein targeting GO:0006605 187 0.014
regulation of catecholamine secretion GO:0050433 1 0.014
cellular lipid catabolic process GO:0044242 65 0.014
steroid biosynthetic process GO:0006694 46 0.014
monosaccharide metabolic process GO:0005996 74 0.014
wound healing GO:0042060 115 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
amino acid transport GO:0006865 28 0.014
locomotory behavior GO:0007626 1 0.014
response to cocaine GO:0042220 1 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
hemopoiesis GO:0030097 180 0.014
cellular component disassembly GO:0022411 92 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
cellular calcium ion homeostasis GO:0006874 117 0.013
renal system process GO:0003014 25 0.013
regulation of nucleotide biosynthetic process GO:0030808 50 0.013
small molecule catabolic process GO:0044282 92 0.013
regulation of phospholipase c activating g protein coupled receptor signaling pathway GO:1900736 1 0.013
cellular component morphogenesis GO:0032989 314 0.013
purine containing compound catabolic process GO:0072523 411 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
intracellular protein transport GO:0006886 270 0.013
menaquinone catabolic process GO:0042361 2 0.013
response to other organism GO:0051707 261 0.013
positive regulation of kinase activity GO:0033674 204 0.013
negative regulation of protein activation cascade GO:2000258 7 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
wnt signaling pathway GO:0016055 156 0.013
nicotinate transport GO:2001142 1 0.013
cell part morphogenesis GO:0032990 137 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
nervous system development GO:0007399 293 0.013
regulation of exocytosis GO:0017157 46 0.013
lipid localization GO:0010876 106 0.013
regulation of cellular response to stress GO:0080135 244 0.013
mitotic cell cycle GO:0000278 326 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
mrna metabolic process GO:0016071 175 0.012
cellular response to external stimulus GO:0071496 111 0.012
rhythmic behavior GO:0007622 2 0.012
cellular macromolecule catabolic process GO:0044265 380 0.012
angiogenesis GO:0001525 147 0.012
negative regulation of protein modification process GO:0031400 200 0.012
covalent chromatin modification GO:0016569 254 0.012
regulation of inflammatory response GO:0050727 46 0.012
protein secretion GO:0009306 98 0.012
cell projection organization GO:0030030 252 0.012
lipid transport GO:0006869 90 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
regulation of cell cycle process GO:0010564 266 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
negative regulation of proteolysis GO:0045861 132 0.012
reproductive process GO:0022414 106 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
response to nutrient levels GO:0031667 81 0.012
oocyte development GO:0048599 1 0.012
oocyte differentiation GO:0009994 2 0.012
mitochondrion organization GO:0007005 156 0.012
quinone catabolic process GO:1901662 2 0.012
generation of precursor metabolites and energy GO:0006091 68 0.012
regulation of phosphatase activity GO:0010921 81 0.012
ribonucleoside catabolic process GO:0042454 406 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
regulation of cytokine production GO:0001817 232 0.012
response to insulin GO:0032868 45 0.012
hindbrain development GO:0030902 3 0.012
regulation of protein maturation GO:1903317 150 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
cytokinesis GO:0000910 96 0.012
peptidyl serine modification GO:0018209 106 0.011
positive regulation of protein secretion GO:0050714 60 0.011
tissue regeneration GO:0042246 3 0.011
circadian behavior GO:0048512 2 0.011
organelle assembly GO:0070925 176 0.011
cellular response to gonadotropin stimulus GO:0071371 4 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
negative regulation of transferase activity GO:0051348 124 0.011
regulation of blood pressure GO:0008217 30 0.011
response to disaccharide GO:0034285 1 0.011
response to peptide GO:1901652 65 0.011
regulation of peptide secretion GO:0002791 42 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
regulation of behavior GO:0050795 82 0.011
response to cytokine GO:0034097 232 0.011
tissue migration GO:0090130 119 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
regulation of adenylate cyclase activity GO:0045761 17 0.011
hormone metabolic process GO:0042445 61 0.011
positive regulation of amine transport GO:0051954 2 0.011
cellular divalent inorganic cation homeostasis GO:0072503 128 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
nuclear transport GO:0051169 179 0.010
regulation of immune effector process GO:0002697 91 0.010
response to growth factor GO:0070848 205 0.010
regulation of vesicle mediated transport GO:0060627 130 0.010
activation of protein kinase activity GO:0032147 90 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
response to purine containing compound GO:0014074 40 0.010
regulation of growth GO:0040008 165 0.010
regulation of mitotic cell cycle GO:0007346 189 0.010
visual learning GO:0008542 1 0.010
ketone biosynthetic process GO:0042181 17 0.010
osteoblast differentiation GO:0001649 92 0.010
negative regulation of kinase activity GO:0033673 106 0.010
metencephalon development GO:0022037 2 0.010
negative regulation of cell motility GO:2000146 104 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
positive regulation of protein catabolic process GO:0045732 75 0.010
negative regulation of defense response GO:0031348 47 0.010
erk1 and erk2 cascade GO:0070371 104 0.010
renal system process involved in regulation of blood volume GO:0001977 4 0.010
ribonucleoside triphosphate catabolic process GO:0009203 391 0.010
regulation of dephosphorylation GO:0035303 96 0.010
bmp signaling pathway GO:0030509 49 0.010

CYP2A6 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.087
immune system disease DOID:2914 155 0.031
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
organ system cancer DOID:0050686 164 0.018
retinal disease DOID:5679 118 0.017
night blindness DOID:8499 10 0.017
sensory system disease DOID:0050155 203 0.017
congenital stationary night blindness DOID:0050534 8 0.017
eye and adnexa disease DOID:1492 150 0.017
nervous system disease DOID:863 431 0.017
eye disease DOID:5614 149 0.017
central nervous system disease DOID:331 186 0.015
acquired metabolic disease DOID:0060158 58 0.012
hematopoietic system disease DOID:74 100 0.011
disease of mental health DOID:150 70 0.006
substance dependence DOID:9973 10 0.001
substance related disorder DOID:303 10 0.001
nicotine dependence DOID:0050742 4 0.001
respiratory system cancer DOID:0050615 16 0.001
lung cancer DOID:1324 16 0.001