Homo sapiens

66 known processes

CYP3A4

cytochrome P450, family 3, subfamily A, polypeptide 4

(Aliases: P450C3,CYPIIIA4,NF-25,CYP3A3,CYPIIIA3,P450PCN1,MGC126680,CP34,HLP,CYP3A,CP33)

CYP3A4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidative demethylation GO:0070989 11 0.979
alkaloid catabolic process GO:0009822 3 0.967
drug catabolic process GO:0042737 10 0.926
vitamin k catabolic process GO:0042377 2 0.841
alkaloid metabolic process GO:0009820 4 0.804
epoxygenase p450 pathway GO:0019373 3 0.779
drug metabolic process GO:0017144 19 0.752
lipid metabolic process GO:0006629 381 0.697
quinone catabolic process GO:1901662 2 0.600
response to xenobiotic stimulus GO:0009410 30 0.591
Zebrafish Fly
steroid metabolic process GO:0008202 94 0.570
phylloquinone metabolic process GO:0042374 2 0.518
monoterpenoid metabolic process GO:0016098 6 0.517
menaquinone catabolic process GO:0042361 2 0.512
vitamin d3 metabolic process GO:0070640 7 0.483
monocarboxylic acid metabolic process GO:0032787 185 0.480
Fly
vitamin e metabolic process GO:0042360 1 0.475
negative regulation of icosanoid secretion GO:0032304 2 0.474
icosanoid catabolic process GO:1901523 2 0.442
cellular organohalogen metabolic process GO:0090345 2 0.441
long chain fatty acid metabolic process GO:0001676 30 0.439
organic hydroxy compound metabolic process GO:1901615 147 0.439
sensory perception of smell GO:0007608 2 0.425
Fly
calcitriol biosynthetic process from calciol GO:0036378 7 0.422
cellular lipid metabolic process GO:0044255 303 0.411
oxidation reduction process GO:0055114 396 0.407
naphthalene metabolic process GO:0018931 1 0.400
leukotriene b4 metabolic process GO:0036102 2 0.361
alcohol metabolic process GO:0006066 114 0.358
toxin metabolic process GO:0009404 4 0.354
Fly
xenobiotic metabolic process GO:0006805 28 0.346
Fly
lipid catabolic process GO:0016042 84 0.337
menaquinone metabolic process GO:0009233 3 0.337
secondary alcohol metabolic process GO:1902652 7 0.323
isoquinoline alkaloid metabolic process GO:0033076 1 0.317
lipid biosynthetic process GO:0008610 177 0.303
demethylation GO:0070988 37 0.298
phenylpropanoid metabolic process GO:0009698 3 0.279
naphthalene containing compound metabolic process GO:0090420 1 0.271
fatty acid metabolic process GO:0006631 115 0.253
Fly
negative regulation of cellular organofluorine metabolic process GO:0090350 1 0.233
leukotriene catabolic process GO:0036100 2 0.231
terpenoid metabolic process GO:0006721 27 0.219
vitamin k biosynthetic process GO:0042371 2 0.208
cellular response to xenobiotic stimulus GO:0071466 29 0.199
Fly
leukotriene b4 catabolic process GO:0036101 2 0.192
small molecule biosynthetic process GO:0044283 157 0.189
coumarin metabolic process GO:0009804 2 0.188
negative regulation of cellular organohalogen metabolic process GO:0090349 1 0.187
chemical homeostasis GO:0048878 306 0.154
cellular response to genistein GO:0071412 1 0.153
cellular ketone metabolic process GO:0042180 80 0.149
Fly
fat soluble vitamin metabolic process GO:0006775 19 0.148
nitrogen cycle metabolic process GO:0071941 3 0.138
fatty acid derivative catabolic process GO:1901569 2 0.129
regulation of cellular organofluorine metabolic process GO:0090348 1 0.119
urea metabolic process GO:0019627 3 0.117
response to organonitrogen compound GO:0010243 156 0.115
Fly
cellular amino acid metabolic process GO:0006520 116 0.112
fatty acid omega oxidation GO:0010430 2 0.108
steroid biosynthetic process GO:0006694 46 0.107
response to organic cyclic compound GO:0014070 204 0.101
Rat Fly
response to hormone GO:0009725 175 0.098
Rat
phylloquinone catabolic process GO:0042376 2 0.098
single organism carbohydrate metabolic process GO:0044723 193 0.093
exogenous drug catabolic process GO:0042738 8 0.093
cellular response to hydroxyisoflavone GO:0071413 1 0.093
cellular organofluorine metabolic process GO:0090346 2 0.092
fatty acid derivative metabolic process GO:1901568 35 0.092
response to caffeine GO:0031000 3 0.090
Fly
defense response GO:0006952 315 0.087
Fly
arachidonic acid metabolic process GO:0019369 14 0.085
medium chain fatty acid metabolic process GO:0051791 4 0.084
Fly
response to mercury ion GO:0046689 4 0.083
Fly
anion transport GO:0006820 161 0.083
unsaturated fatty acid metabolic process GO:0033559 37 0.082
organic anion transport GO:0015711 103 0.080
renal water homeostasis GO:0003091 4 0.078
immune response GO:0006955 307 0.077
organic hydroxy compound biosynthetic process GO:1901617 71 0.077
regulation of response to external stimulus GO:0032101 222 0.074
response to nitrogen compound GO:1901698 184 0.074
Fly
regulation of cellular organohalogen metabolic process GO:0090347 1 0.073
pressure natriuresis GO:0003095 2 0.072
response to metal ion GO:0010038 84 0.067
Rat Fly
protein processing GO:0016485 226 0.064
linoleic acid metabolic process GO:0043651 4 0.063
long chain fatty acid catabolic process GO:0042758 3 0.062
carbohydrate metabolic process GO:0005975 207 0.062
post embryonic development GO:0009791 2 0.061
Fly
ketone catabolic process GO:0042182 3 0.061
regulation of cellular amino acid metabolic process GO:0006521 6 0.058
response to lipid GO:0033993 206 0.057
Rat
system process GO:0003008 349 0.056
Fly
icosanoid metabolic process GO:0006690 35 0.056
response to other organism GO:0051707 261 0.056
Fly
cellular response to endogenous stimulus GO:0071495 336 0.054
response to drug GO:0042493 81 0.052
protein maturation GO:0051604 233 0.052
response to inorganic substance GO:0010035 127 0.050
Rat Fly
glycerolipid metabolic process GO:0046486 107 0.050
regulation of cellular amine metabolic process GO:0033238 11 0.050
sensory perception of chemical stimulus GO:0007606 38 0.050
Fly
organic acid biosynthetic process GO:0016053 97 0.050
cellular amine metabolic process GO:0044106 41 0.049
response to abiotic stimulus GO:0009628 336 0.049
Fly
response to steroid hormone GO:0048545 80 0.048
Rat
estrogen catabolic process GO:0006711 1 0.048
cellular response to oxygen containing compound GO:1901701 276 0.047
ion homeostasis GO:0050801 230 0.046
purine containing compound catabolic process GO:0072523 411 0.046
negative regulation of protein metabolic process GO:0051248 391 0.045
regulation of cellular ketone metabolic process GO:0010565 50 0.045
steroid catabolic process GO:0006706 10 0.044
defense response to other organism GO:0098542 129 0.044
Fly
nucleoside phosphate catabolic process GO:1901292 412 0.044
isoprenoid metabolic process GO:0006720 39 0.043
alcohol biosynthetic process GO:0046165 52 0.043
regulation of hormone levels GO:0010817 125 0.042
Fly
response to wounding GO:0009611 168 0.042
hemostasis GO:0007599 76 0.041
multicellular organismal aging GO:0010259 3 0.041
ras protein signal transduction GO:0007265 73 0.040
determination of adult lifespan GO:0008340 2 0.040
epithelial cell differentiation GO:0030855 141 0.040
ribonucleotide catabolic process GO:0009261 405 0.039
purine ribonucleoside metabolic process GO:0046128 437 0.039
cellular amide metabolic process GO:0043603 69 0.039
positive regulation of fatty acid transport GO:2000193 3 0.039
purine nucleotide catabolic process GO:0006195 405 0.038
amine metabolic process GO:0009308 44 0.038
response to biotic stimulus GO:0009607 276 0.038
Fly
negative regulation of response to external stimulus GO:0032102 83 0.038
positive regulation of hormone biosynthetic process GO:0046886 4 0.037
polyol metabolic process GO:0019751 32 0.037
lipid transport GO:0006869 90 0.037
regulation of kinase activity GO:0043549 314 0.037
sulfur compound metabolic process GO:0006790 101 0.037
positive regulation of catabolic process GO:0009896 310 0.037
cytoplasmic transport GO:0016482 379 0.037
regulation of cell differentiation GO:0045595 393 0.036
nucleoside catabolic process GO:0009164 408 0.036
regulation of transferase activity GO:0051338 355 0.036
renal system process involved in regulation of blood volume GO:0001977 4 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.035
response to oxygen containing compound GO:1901700 369 0.035
nucleoside triphosphate metabolic process GO:0009141 422 0.034
sensory perception GO:0007600 103 0.034
Fly
neurological system process GO:0050877 163 0.034
Fly
small gtpase mediated signal transduction GO:0007264 78 0.034
regulation of protein kinase activity GO:0045859 289 0.034
cellular lipid catabolic process GO:0044242 65 0.034
organophosphate catabolic process GO:0046434 430 0.034
response to external biotic stimulus GO:0043207 261 0.033
Fly
innate immune response GO:0045087 178 0.033
purine nucleoside triphosphate catabolic process GO:0009146 392 0.033
single organism membrane organization GO:0044802 268 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.033
cation homeostasis GO:0055080 189 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
negative regulation of cell proliferation GO:0008285 228 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
regulation of growth GO:0040008 165 0.032
Fly
negative regulation of multicellular organismal process GO:0051241 317 0.032
membrane organization GO:0061024 292 0.032
secretion GO:0046903 254 0.032
glycosyl compound catabolic process GO:1901658 413 0.031
wound healing GO:0042060 115 0.031
vitamin metabolic process GO:0006766 26 0.031
regulation of locomotion GO:0040012 329 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.031
carbohydrate derivative biosynthetic process GO:1901137 207 0.030
ribonucleoside catabolic process GO:0042454 406 0.030
regulation of anatomical structure morphogenesis GO:0022603 286 0.030
regeneration GO:0031099 4 0.030
carboxylic acid biosynthetic process GO:0046394 97 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
vesicle mediated transport GO:0016192 371 0.030
regulation of response to wounding GO:1903034 101 0.030
locomotory behavior GO:0007626 1 0.029
biological adhesion GO:0022610 331 0.029
cellular homeostasis GO:0019725 196 0.029
lipid modification GO:0030258 84 0.029
response to bacterium GO:0009617 144 0.028
Fly
metal ion homeostasis GO:0055065 169 0.028
regulation of nucleotide metabolic process GO:0006140 269 0.028
positive regulation of immune system process GO:0002684 283 0.028
female gamete generation GO:0007292 2 0.028
regulation of cell cycle GO:0051726 393 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
regulation of cell migration GO:0030334 289 0.028
actin filament based process GO:0030029 224 0.028
regulation of cellular component biogenesis GO:0044087 281 0.028
lipid localization GO:0010876 106 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
nervous system development GO:0007399 293 0.027
single organism cellular localization GO:1902580 332 0.027
carboxylic acid catabolic process GO:0046395 71 0.027
cellular cation homeostasis GO:0030003 163 0.027
behavior GO:0007610 112 0.027
Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.027
neuromuscular junction development GO:0007528 3 0.027
regulation of wound healing GO:0061041 56 0.027
regulation of cell motility GO:2000145 299 0.027
regulation of lipid metabolic process GO:0019216 96 0.027
regulation of proteolysis GO:0030162 293 0.026
coagulation GO:0050817 78 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
rho protein signal transduction GO:0007266 26 0.026
cell adhesion GO:0007155 325 0.026
cellular response to nitrogen compound GO:1901699 144 0.026
positive regulation of organic acid transport GO:0032892 3 0.026
transmembrane transport GO:0055085 399 0.026
cellular ion homeostasis GO:0006873 168 0.026
uronic acid metabolic process GO:0006063 16 0.026
positive regulation of transport GO:0051050 336 0.026
cellular hormone metabolic process GO:0034754 41 0.026
Fly
positive regulation of hydrolase activity GO:0051345 331 0.025
regulation of icosanoid secretion GO:0032303 4 0.025
response to growth factor GO:0070848 205 0.025
small molecule catabolic process GO:0044282 92 0.025
negative regulation of phosphate metabolic process GO:0045936 267 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
signal transduction by phosphorylation GO:0023014 297 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
regulation of coagulation GO:0050818 44 0.025
negative regulation of transport GO:0051051 176 0.025
regulation of binding GO:0051098 111 0.025
positive regulation of phosphorylation GO:0042327 394 0.024
enzyme linked receptor protein signaling pathway GO:0007167 303 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
cellular component morphogenesis GO:0032989 314 0.024
organic acid catabolic process GO:0016054 71 0.024
positive regulation of protein phosphorylation GO:0001934 313 0.024
nucleotide catabolic process GO:0009166 408 0.024
protein localization to membrane GO:0072657 160 0.024
oogenesis GO:0048477 2 0.024
negative regulation of locomotion GO:0040013 118 0.024
negative regulation of hemostasis GO:1900047 22 0.023
fat soluble vitamin biosynthetic process GO:0042362 11 0.023
cell morphogenesis GO:0000902 296 0.023
positive regulation of cell death GO:0010942 263 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
maintenance of location GO:0051235 112 0.023
response to cytokine GO:0034097 232 0.023
cellular response to cytokine stimulus GO:0071345 181 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.023
secondary metabolic process GO:0019748 17 0.023
Fly
chemotaxis GO:0006935 157 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
negative regulation of response to wounding GO:1903035 47 0.022
positive regulation of protein kinase activity GO:0045860 190 0.022
regulation of immune response GO:0050776 201 0.022
regulation of protein maturation GO:1903317 150 0.022
defense response to bacterium GO:0042742 63 0.022
Fly
positive regulation of cell differentiation GO:0045597 211 0.022
protein catabolic process GO:0030163 325 0.022
cytokine production GO:0001816 247 0.022
cell development GO:0048468 328 0.022
growth GO:0040007 202 0.022
Fly
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
cellular response to organic cyclic compound GO:0071407 127 0.022
response to nutrient levels GO:0031667 81 0.022
Rat
regulation of ion transport GO:0043269 189 0.021
regulation of body fluid levels GO:0050878 99 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
blood coagulation GO:0007596 76 0.021
carboxylic acid transport GO:0046942 63 0.021
taxis GO:0042330 157 0.021
response to organophosphorus GO:0046683 41 0.021
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.021
endomembrane system organization GO:0010256 196 0.021
memory GO:0007613 3 0.021
actin cytoskeleton organization GO:0030036 207 0.021
organic acid transport GO:0015849 65 0.021
cell projection organization GO:0030030 252 0.021
response to nutrient GO:0007584 20 0.021
Rat
cellular metal ion homeostasis GO:0006875 146 0.021
cofactor metabolic process GO:0051186 87 0.021
positive regulation of programmed cell death GO:0043068 249 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
lipid oxidation GO:0034440 33 0.021
negative regulation of protein maturation GO:1903318 142 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
regulation of protein localization GO:0032880 296 0.021
cellular response to organonitrogen compound GO:0071417 124 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
secretion by cell GO:0032940 226 0.021
mitotic cell cycle GO:0000278 326 0.020
regulation of protein processing GO:0070613 150 0.020
regulation of cellular component movement GO:0051270 334 0.020
regulation of cellular response to stress GO:0080135 244 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
positive regulation of transferase activity GO:0051347 227 0.020
negative regulation of protein modification process GO:0031400 200 0.020
hemopoiesis GO:0030097 180 0.020
cation transport GO:0006812 331 0.020
leukotriene metabolic process GO:0006691 10 0.020
phospholipid metabolic process GO:0006644 99 0.020
positive regulation of kinase activity GO:0033674 204 0.020
protein localization to organelle GO:0033365 280 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
mitotic cell cycle process GO:1903047 286 0.020
regulation of cell cycle process GO:0010564 266 0.020
regulation of mapk cascade GO:0043408 262 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
negative regulation of cell death GO:0060548 345 0.019
monocarboxylic acid biosynthetic process GO:0072330 67 0.019
regulation of lipid biosynthetic process GO:0046890 47 0.019
immune effector process GO:0002252 159 0.019
coenzyme metabolic process GO:0006732 65 0.019
dephosphorylation GO:0016311 209 0.019
vitamin catabolic process GO:0009111 6 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
cellular response to hormone stimulus GO:0032870 125 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
positive regulation of developmental process GO:0051094 314 0.019
divalent inorganic cation homeostasis GO:0072507 136 0.019
purine nucleoside monophosphate metabolic process GO:0009126 186 0.019
fat soluble vitamin catabolic process GO:0042363 6 0.018
spermatid differentiation GO:0048515 4 0.018
protein oligomerization GO:0051259 173 0.018
protein targeting GO:0006605 187 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
regulation of secretion by cell GO:1903530 177 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
positive regulation of cell migration GO:0030335 172 0.018
regulation of protein transport GO:0051223 213 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
positive regulation of secretion GO:0051047 116 0.018
nitrogen compound transport GO:0071705 191 0.018
mapk cascade GO:0000165 288 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
intracellular protein transport GO:0006886 270 0.018
cellular protein complex assembly GO:0043623 188 0.017
negative regulation of protein processing GO:0010955 142 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
reactive nitrogen species metabolic process GO:2001057 3 0.017
regulation of cytokine production GO:0001817 232 0.017
oocyte differentiation GO:0009994 2 0.017
multi organism cellular process GO:0044764 156 0.017
blood vessel development GO:0001568 172 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017
atp metabolic process GO:0046034 176 0.017
generation of neurons GO:0048699 152 0.017
immune system development GO:0002520 195 0.017
response to phenylpropanoid GO:0080184 1 0.017
ion transmembrane transport GO:0034220 338 0.017
cellular carbohydrate metabolic process GO:0044262 84 0.017
micturition GO:0060073 3 0.017
negative regulation of wound healing GO:0061045 25 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
monocarboxylic acid catabolic process GO:0072329 37 0.017
hormone metabolic process GO:0042445 61 0.017
Fly
reactive oxygen species metabolic process GO:0072593 75 0.017
regulation of intracellular transport GO:0032386 195 0.017
negative regulation of developmental process GO:0051093 247 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
apoptotic signaling pathway GO:0097190 268 0.017
negative regulation of phosphorylation GO:0042326 174 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
epithelial cell proliferation GO:0050673 128 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.016
response to extracellular stimulus GO:0009991 85 0.016
Rat
regulation of peptidase activity GO:0052547 180 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
positive regulation of icosanoid secretion GO:0032305 3 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.016
regulation of defense response GO:0031347 154 0.016
vitamin d metabolic process GO:0042359 10 0.016
adult locomotory behavior GO:0008344 1 0.016
single organism cell adhesion GO:0098602 179 0.016
plasma membrane organization GO:0007009 115 0.016
angiogenesis GO:0001525 147 0.016
associative learning GO:0008306 1 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
oocyte development GO:0048599 1 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
interspecies interaction between organisms GO:0044419 156 0.016
vitamin biosynthetic process GO:0009110 11 0.015
positive regulation of proteolysis GO:0045862 142 0.015
negative regulation of blood coagulation GO:0030195 22 0.015
cellular chemical homeostasis GO:0055082 180 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
viral process GO:0016032 146 0.015
negative regulation of cell motility GO:2000146 104 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
cellular modified amino acid metabolic process GO:0006575 64 0.015
regulation of cell development GO:0060284 161 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
segmentation GO:0035282 4 0.015
blood circulation GO:0008015 113 0.015
regulation of cell adhesion GO:0030155 166 0.015
rhythmic behavior GO:0007622 2 0.015
response to genistein GO:0033595 1 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
response to fungus GO:0009620 4 0.015
positive regulation of ion transport GO:0043270 87 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
response to purine containing compound GO:0014074 40 0.015
Fly
divalent metal ion transport GO:0070838 152 0.015
ossification GO:0001503 121 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
positive regulation of cell motility GO:2000147 177 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
gtp metabolic process GO:0046039 239 0.015
vitamin k metabolic process GO:0042373 6 0.015
limbic system development GO:0021761 3 0.015
myeloid cell differentiation GO:0030099 117 0.015
protein ubiquitination GO:0016567 314 0.015
spermatid development GO:0007286 4 0.015
regulation of blood coagulation GO:0030193 42 0.015
cell growth GO:0016049 160 0.015
response to decreased oxygen levels GO:0036293 96 0.015
neutral lipid metabolic process GO:0006638 27 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
tissue migration GO:0090130 119 0.015
regulation of gtpase activity GO:0043087 180 0.014
epithelium development GO:0060429 227 0.014
positive regulation of immune response GO:0050778 159 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
sensory perception of pain GO:0019233 4 0.014
sequestering of metal ion GO:0051238 24 0.014
vasculature development GO:0001944 181 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
gtp catabolic process GO:0006184 237 0.014
negative regulation of cellular component movement GO:0051271 106 0.014
visual behavior GO:0007632 2 0.014
cell projection assembly GO:0030031 126 0.014
regulation of cell growth GO:0001558 135 0.014
regulation of multi organism process GO:0043900 157 0.014
response to hypoxia GO:0001666 96 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
ketone biosynthetic process GO:0042181 17 0.014
Fly
anterior posterior axis specification GO:0009948 2 0.014
monosaccharide metabolic process GO:0005996 74 0.014
calcium ion homeostasis GO:0055074 122 0.014
intracellular receptor signaling pathway GO:0030522 104 0.014
9 cis retinoic acid metabolic process GO:0042905 1 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
negative regulation of proteolysis GO:0045861 132 0.014
positive regulation of organelle organization GO:0010638 195 0.014
cellular glucuronidation GO:0052695 16 0.014
regulation of actin filament based process GO:0032970 141 0.014
positive regulation of gtpase activity GO:0043547 166 0.014
testosterone biosynthetic process GO:0061370 2 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
purine containing compound biosynthetic process GO:0072522 88 0.014
response to alcohol GO:0097305 64 0.014
peptide metabolic process GO:0006518 51 0.014
negative regulation of programmed cell death GO:0043069 321 0.013
tissue regeneration GO:0042246 3 0.013
cellular protein catabolic process GO:0044257 261 0.013
regulation of homeostatic process GO:0032844 121 0.013
defense response to fungus GO:0050832 4 0.013
blastoderm segmentation GO:0007350 2 0.013
negative regulation of organelle organization GO:0010639 126 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
acylglycerol metabolic process GO:0006639 27 0.013
circulatory system development GO:0072359 262 0.013
epithelium migration GO:0090132 119 0.013
regulation of secretion GO:0051046 194 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
glycerophospholipid metabolic process GO:0006650 84 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
negative regulation of cell migration GO:0030336 102 0.013

CYP3A4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.066
inherited metabolic disorder DOID:655 242 0.062
sensory system disease DOID:0050155 203 0.029
nervous system disease DOID:863 431 0.029
hematopoietic system disease DOID:74 100 0.026
immune system disease DOID:2914 155 0.026
amino acid metabolic disorder DOID:9252 50 0.022
central nervous system disease DOID:331 186 0.019
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
cardiovascular system disease DOID:1287 106 0.017
Human
organ system cancer DOID:0050686 164 0.016
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015
musculoskeletal system disease DOID:17 223 0.014
retinal disease DOID:5679 118 0.013
connective tissue disease DOID:65 109 0.013