Homo sapiens

145 known processes

DDX5

DEAD (Asp-Glu-Ala-Asp) box polypeptide 5

(Aliases: p68,HUMP68,G17P1,DKFZp434E109,DKFZp686J01190,HLR1)

DDX5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna splicing GO:0008380 131 0.993
rna processing GO:0006396 255 0.982
mrna metabolic process GO:0016071 175 0.947
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.947
epithelium development GO:0060429 227 0.910
nervous system development GO:0007399 293 0.904
Fly
ribonucleoprotein complex subunit organization GO:0071826 81 0.864
Yeast
positive regulation of dna damage response signal transduction by p53 class mediator GO:0043517 8 0.832
regulation of skeletal muscle cell differentiation GO:2001014 3 0.827
Human Mouse
mrna processing GO:0006397 133 0.826
regulation of cell differentiation GO:0045595 393 0.824
Human Mouse
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.820
post embryonic development GO:0009791 2 0.816
Worm
rna splicing via transesterification reactions GO:0000375 90 0.799
determination of adult lifespan GO:0008340 2 0.745
gene silencing GO:0016458 49 0.731
Fly
female gamete generation GO:0007292 2 0.698
muscle tissue development GO:0060537 62 0.650
Human Mouse
response to biotic stimulus GO:0009607 276 0.649
Fly
growth GO:0040007 202 0.641
polyadenylation dependent mrna catabolic process GO:0071047 1 0.612
Yeast
organelle fission GO:0048285 149 0.604
epidermal cell differentiation GO:0009913 45 0.590
regulation of mrna splicing via spliceosome GO:0048024 32 0.586
muscle structure development GO:0061061 98 0.575
Human Mouse
mitotic cell cycle GO:0000278 326 0.566
positive regulation of nucleobase containing compound transport GO:0032241 1 0.558
multicellular organismal aging GO:0010259 3 0.538
ribonucleoprotein complex biogenesis GO:0022613 116 0.526
Yeast
regulation of rna splicing GO:0043484 62 0.525
neurogenesis GO:0022008 169 0.504
Fly
reproductive system development GO:0061458 56 0.478
response to other organism GO:0051707 261 0.437
Fly
oogenesis GO:0048477 2 0.432
epithelial cell differentiation GO:0030855 141 0.401
mitotic cell cycle process GO:1903047 286 0.387
positive regulation of developmental process GO:0051094 314 0.383
response to external biotic stimulus GO:0043207 261 0.375
Fly
regulation of keratinocyte differentiation GO:0045616 11 0.367
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.361
keratinocyte differentiation GO:0030216 36 0.351
rna stabilization GO:0043489 18 0.349
spermatid development GO:0007286 4 0.336
posttranscriptional gene silencing by rna GO:0035194 25 0.327
Fly
cellular macromolecule catabolic process GO:0044265 380 0.282
Yeast
stem cell differentiation GO:0048863 93 0.279
nucleobase containing compound transport GO:0015931 51 0.279
osteoblast differentiation GO:0001649 92 0.268
Mouse
defense response GO:0006952 315 0.252
regulation of transcription by galactose GO:0000409 1 0.249
response to lipopolysaccharide GO:0032496 70 0.240
intrinsic apoptotic signaling pathway GO:0097193 127 0.234
female genitalia development GO:0030540 2 0.227
embryo development GO:0009790 123 0.226
Mouse Worm
mitotic nuclear division GO:0007067 119 0.216
intracellular receptor signaling pathway GO:0030522 104 0.213
response to extracellular stimulus GO:0009991 85 0.208
nuclear division GO:0000280 128 0.205
ncrna processing GO:0034470 83 0.205
Yeast
androgen receptor signaling pathway GO:0030521 34 0.199
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.194
spermatid differentiation GO:0048515 4 0.190
cell junction assembly GO:0034329 67 0.190
immune response GO:0006955 307 0.188
Fly
carbohydrate metabolic process GO:0005975 207 0.183
apoptotic signaling pathway GO:0097190 268 0.182
positive regulation of transcription by galactose GO:0000411 1 0.180
skeletal muscle organ development GO:0060538 26 0.177
Human Mouse
regulation of low density lipoprotein particle receptor biosynthetic process GO:0045714 4 0.175
carbon catabolite activation of transcription GO:0045991 3 0.169
response to abiotic stimulus GO:0009628 336 0.168
internal protein amino acid acetylation GO:0006475 101 0.163
developmental process involved in reproduction GO:0003006 66 0.159
chromatin organization GO:0006325 351 0.155
cellular response to endogenous stimulus GO:0071495 336 0.153
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 3 0.148
cellular macromolecular complex assembly GO:0034622 324 0.141
Yeast
regulation of signal transduction by p53 class mediator GO:1901796 26 0.138
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.137
developmental growth GO:0048589 48 0.136
negative regulation of cell death GO:0060548 345 0.132
response to nutrient levels GO:0031667 81 0.131
intracellular estrogen receptor signaling pathway GO:0030520 23 0.126
rna interference GO:0016246 4 0.122
Fly
epidermis development GO:0008544 59 0.121
negative regulation of developmental process GO:0051093 247 0.121
neuron differentiation GO:0030182 138 0.120
regulation of cellular ketone metabolic process GO:0010565 50 0.120
positive regulation of translation GO:0045727 35 0.120
mating GO:0007618 1 0.119
ncrna metabolic process GO:0034660 108 0.115
Yeast
nucleic acid transport GO:0050657 39 0.113
chordate embryonic development GO:0043009 34 0.113
Mouse
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.112
humoral immune response GO:0006959 49 0.109
Fly
female sex differentiation GO:0046660 12 0.108
cerebellum development GO:0021549 2 0.107
regulation of cellular response to stress GO:0080135 244 0.105
histone h4 acetylation GO:0043967 47 0.105
translation GO:0006412 132 0.102
regulation of muscle tissue development GO:1901861 26 0.102
Human Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 3 0.101
internal peptidyl lysine acetylation GO:0018393 97 0.101
negative regulation of rna splicing GO:0033119 15 0.100
nitrogen compound transport GO:0071705 191 0.099
cellular response to dna damage stimulus GO:0006974 379 0.098
embryo development ending in birth or egg hatching GO:0009792 34 0.097
Mouse Worm
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.097
dna templated transcription elongation GO:0006354 25 0.097
regulation of growth GO:0040008 165 0.097
rrna metabolic process GO:0016072 40 0.094
Yeast
regulation of striated muscle tissue development GO:0016202 26 0.093
Human Mouse
nuclear export GO:0051168 69 0.092
female gonad development GO:0008585 10 0.090
nuclear transport GO:0051169 179 0.088
reproductive structure development GO:0048608 55 0.088
response to bacterium GO:0009617 144 0.087
muscle contraction GO:0006936 73 0.085
alternative mrna splicing via spliceosome GO:0000380 27 0.084
mrna splicing via spliceosome GO:0000398 89 0.083
establishment of rna localization GO:0051236 39 0.083
chemical homeostasis GO:0048878 306 0.082
posttranscriptional regulation of gene expression GO:0010608 213 0.079
Fly
muscle organ development GO:0007517 56 0.078
Human Mouse
rrna processing GO:0006364 35 0.076
Yeast
nucleocytoplasmic transport GO:0006913 176 0.076
positive regulation of cell differentiation GO:0045597 211 0.071
skeletal muscle cell differentiation GO:0035914 6 0.071
Human Mouse
sex differentiation GO:0007548 45 0.070
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 5 0.070
cell junction organization GO:0034330 79 0.070
skeletal muscle tissue development GO:0007519 24 0.068
Human Mouse
response to starvation GO:0042594 59 0.066
regulation of neurotransmitter secretion GO:0046928 3 0.065
embryonic placenta development GO:0001892 1 0.062
regulation of response to wounding GO:1903034 101 0.062
rna catabolic process GO:0006401 71 0.059
Yeast
cap independent translational initiation GO:0002190 4 0.058
negative regulation of protein metabolic process GO:0051248 391 0.056
aging GO:0007568 66 0.056
regulation of epidermis development GO:0045682 19 0.056
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.055
Yeast
striated muscle tissue development GO:0014706 59 0.053
Human Mouse
carbohydrate derivative biosynthetic process GO:1901137 207 0.053
regulation of epidermal cell differentiation GO:0045604 15 0.051
negative regulation of synaptic transmission GO:0050805 2 0.050
regulation of anatomical structure size GO:0090066 101 0.050
regulation of response to dna damage stimulus GO:2001020 94 0.049
rna transport GO:0050658 39 0.049
cellular amine metabolic process GO:0044106 41 0.048
lipid biosynthetic process GO:0008610 177 0.048
single organism carbohydrate metabolic process GO:0044723 193 0.048
negative regulation of cellular protein metabolic process GO:0032269 353 0.048
histone acetylation GO:0016573 93 0.047
protein acetylation GO:0006473 116 0.047
regulation of multicellular organism growth GO:0040014 8 0.047
positive regulation of cell death GO:0010942 263 0.047
cell division GO:0051301 168 0.046
cell development GO:0048468 328 0.045
response to steroid hormone GO:0048545 80 0.045
protein acylation GO:0043543 138 0.045
gene silencing by rna GO:0031047 26 0.044
Fly
male meiosis GO:0007140 1 0.044
regulation of mrna processing GO:0050684 48 0.044
cellular ketone metabolic process GO:0042180 80 0.044
somitogenesis GO:0001756 2 0.043
amine metabolic process GO:0009308 44 0.042
regulation of meiosis GO:0040020 3 0.042
ribonucleoprotein complex assembly GO:0022618 78 0.042
Yeast
response to molecule of bacterial origin GO:0002237 82 0.042
male sex differentiation GO:0046661 25 0.041
immune system development GO:0002520 195 0.041
mrna splice site selection GO:0006376 7 0.041
ribosome biogenesis GO:0042254 48 0.040
Yeast
reproductive process GO:0022414 106 0.040
positive regulation of apoptotic process GO:0043065 246 0.040
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter GO:0072367 4 0.039
signal transduction by p53 class mediator GO:0072331 72 0.039
development of primary female sexual characteristics GO:0046545 10 0.039
development of primary sexual characteristics GO:0045137 35 0.038
circulatory system development GO:0072359 262 0.038
glycosyl compound catabolic process GO:1901658 413 0.037
Yeast
histone modification GO:0016570 251 0.037
single organism reproductive process GO:0044702 98 0.037
negative regulation of catalytic activity GO:0043086 335 0.036
regulation of muscle organ development GO:0048634 27 0.035
Human Mouse
multi organism reproductive process GO:0044703 54 0.035
meiotic nuclear division GO:0007126 10 0.035
hemopoiesis GO:0030097 180 0.034
regulation of gene expression epigenetic GO:0040029 73 0.034
Fly
response to temperature stimulus GO:0009266 22 0.033
hematopoietic or lymphoid organ development GO:0048534 186 0.033
regulation of lipid metabolic process GO:0019216 96 0.033
cellular response to toxic substance GO:0097237 4 0.033
receptor metabolic process GO:0043112 81 0.033
response to lipid GO:0033993 206 0.031
nuclear transcribed mrna catabolic process GO:0000956 48 0.031
Yeast
covalent chromatin modification GO:0016569 254 0.031
cell projection organization GO:0030030 252 0.031
metal ion homeostasis GO:0055065 169 0.031
low density lipoprotein particle clearance GO:0034383 8 0.030
regulation of cell cycle process GO:0010564 266 0.030
positive regulation of glucocorticoid receptor signaling pathway GO:2000324 1 0.030
regulation of immune response GO:0050776 201 0.030
multicellular organismal reproductive process GO:0048609 40 0.029
chromosome segregation GO:0007059 114 0.028
metencephalon development GO:0022037 2 0.028
positive regulation of cell activation GO:0050867 81 0.028
oocyte development GO:0048599 1 0.027
regulation of reactive oxygen species metabolic process GO:2000377 41 0.027
reproduction GO:0000003 63 0.027
positive regulation of growth GO:0045927 58 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
negative regulation of mrna metabolic process GO:1903312 15 0.027
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.026
response to oxygen containing compound GO:1901700 369 0.026
regulation of synaptic vesicle exocytosis GO:2000300 2 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
Yeast
negative regulation of secretion by cell GO:1903531 52 0.025
regulation of cell morphogenesis GO:0022604 153 0.025
rna localization GO:0006403 41 0.025
neurotransmitter secretion GO:0007269 4 0.025
neurological system process GO:0050877 163 0.025
cell adhesion GO:0007155 325 0.025
regulation of anatomical structure morphogenesis GO:0022603 286 0.025
gene silencing by mirna GO:0035195 23 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
cell substrate junction assembly GO:0007044 35 0.024
mononuclear cell proliferation GO:0032943 71 0.024
mrna stabilization GO:0048255 18 0.024
cellular amino acid metabolic process GO:0006520 116 0.024
central nervous system development GO:0007417 123 0.024
regulation of translation GO:0006417 89 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.023
Yeast
ossification GO:0001503 121 0.023
Mouse
ribonucleotide catabolic process GO:0009261 405 0.023
Yeast
negative regulation of protein modification process GO:0031400 200 0.023
cytoplasmic translational initiation GO:0002183 6 0.023
protein methylation GO:0006479 74 0.023
ires dependent translational initiation GO:0002192 4 0.023
wound healing GO:0042060 115 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
response to nitrogen compound GO:1901698 184 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.023
Yeast
regulation of leukocyte activation GO:0002694 115 0.022
multicellular organism reproduction GO:0032504 42 0.022
genitalia development GO:0048806 10 0.022
biological adhesion GO:0022610 331 0.022
branching morphogenesis of an epithelial tube GO:0048754 19 0.022
response to heat GO:0009408 21 0.022
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.022
regulation of developmental growth GO:0048638 30 0.022
protein dna complex subunit organization GO:0071824 80 0.022
signal transduction by phosphorylation GO:0023014 297 0.021
cellular lipid metabolic process GO:0044255 303 0.021
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
cellular chemical homeostasis GO:0055082 180 0.021
sister chromatid segregation GO:0000819 54 0.021
hindbrain development GO:0030902 3 0.021
positive regulation of rna export from nucleus GO:0046833 1 0.020
positive regulation of epidermis development GO:0045684 11 0.020
stem cell division GO:0017145 2 0.020
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
Yeast
cytoplasmic transport GO:0016482 379 0.020
peptidyl lysine modification GO:0018205 144 0.020
response to transforming growth factor beta GO:0071559 94 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
signal transduction in response to dna damage GO:0042770 57 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.020
spliceosomal complex assembly GO:0000245 17 0.020
positive regulation of response to dna damage stimulus GO:2001022 43 0.020
actin cytoskeleton organization GO:0030036 207 0.020
regulation of leukocyte proliferation GO:0070663 67 0.019
lipid metabolic process GO:0006629 381 0.019
mapk cascade GO:0000165 288 0.019
sex determination GO:0007530 3 0.019
small gtpase mediated signal transduction GO:0007264 78 0.018
negative regulation of protein phosphorylation GO:0001933 140 0.018
meiotic chromosome segregation GO:0045132 4 0.018
regulation of secretion GO:0051046 194 0.018
regulation of meiotic cell cycle GO:0051445 4 0.018
nuclear import GO:0051170 106 0.018
response to hypoxia GO:0001666 96 0.018
cellular homeostasis GO:0019725 196 0.018
cellular response to extracellular stimulus GO:0031668 72 0.018
positive regulation of multicellular organism growth GO:0040018 6 0.018
positive regulation of b cell activation GO:0050871 17 0.018
blastocyst formation GO:0001825 3 0.017
organophosphate catabolic process GO:0046434 430 0.017
Yeast
trophectodermal cell differentiation GO:0001829 3 0.017
synaptic transmission GO:0007268 61 0.017
regulation of transferase activity GO:0051338 355 0.017
cellular response to nutrient levels GO:0031669 69 0.017
chromatin modification GO:0016568 298 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
positive regulation of kinase activity GO:0033674 204 0.017
dna recombination GO:0006310 77 0.017
spermatogenesis GO:0007283 22 0.017
positive regulation of cellular component biogenesis GO:0044089 158 0.017
calcium mediated signaling GO:0019722 44 0.016
synaptic vesicle exocytosis GO:0016079 3 0.016
positive regulation of leukocyte activation GO:0002696 80 0.016
cell fate determination GO:0001709 3 0.016
secretion GO:0046903 254 0.016
cell morphogenesis GO:0000902 296 0.016
gonad development GO:0008406 34 0.016
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.016
epithelial cell proliferation GO:0050673 128 0.016
macromolecule methylation GO:0043414 97 0.016
response to cytokine GO:0034097 232 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
hemidesmosome assembly GO:0031581 5 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
actin filament organization GO:0007015 128 0.015
cellular component disassembly GO:0022411 92 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
Yeast
regeneration GO:0031099 4 0.015
negative regulation of organelle organization GO:0010639 126 0.015
regulation of chromosome organization GO:0033044 103 0.015
maintenance of location GO:0051235 112 0.015
dna conformation change GO:0071103 113 0.015
hexose metabolic process GO:0019318 55 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
Yeast
positive regulation of epithelial cell differentiation GO:0030858 14 0.015
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 20 0.015
embryonic hemopoiesis GO:0035162 4 0.015
positive regulation of transport GO:0051050 336 0.015
system process GO:0003008 349 0.015
cell growth GO:0016049 160 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
Yeast
blastoderm segmentation GO:0007350 2 0.014
positive regulation of epidermal cell differentiation GO:0045606 8 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
sexual reproduction GO:0019953 37 0.014
cell projection morphogenesis GO:0048858 129 0.014
regulation of protein binding GO:0043393 66 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
Yeast
positive regulation of developmental growth GO:0048639 16 0.014
response to estrogen GO:0043627 47 0.014
regulation of transmembrane transport GO:0034762 139 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
regulation of protein complex assembly GO:0043254 147 0.013
cellular response to external stimulus GO:0071496 111 0.013
multi organism metabolic process GO:0044033 41 0.013
regulation of lipid transport GO:0032368 44 0.013
regulation of rna stability GO:0043487 23 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
lymphocyte activation GO:0046649 133 0.013
stem cell development GO:0048864 69 0.013
regulation of mrna metabolic process GO:1903311 53 0.013
response to interferon gamma GO:0034341 39 0.013
regulation of cytoskeleton organization GO:0051493 177 0.012
regulation of cell motility GO:2000145 299 0.012
regulation of cell projection organization GO:0031344 107 0.012
viral gene expression GO:0019080 35 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
leukocyte activation GO:0045321 164 0.012
dna templated transcription initiation GO:0006352 35 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
peptidyl lysine acetylation GO:0018394 101 0.012
regulation of wound healing GO:0061041 56 0.012
cellular ion homeostasis GO:0006873 168 0.012
regulation of intracellular transport GO:0032386 195 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
cellular response to hypoxia GO:0071456 51 0.012
myoblast differentiation GO:0045445 21 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
embryonic camera type eye development GO:0031076 2 0.011
dosage compensation GO:0007549 3 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
Yeast
microtubule based process GO:0007017 210 0.011
stem cell maintenance GO:0019827 19 0.011
dna repair GO:0006281 198 0.011
regulation of lymphocyte activation GO:0051249 103 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.011
glycerolipid metabolic process GO:0046486 107 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.011
organelle assembly GO:0070925 176 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
regulation of epithelial cell differentiation GO:0030856 24 0.011
regulation of cell migration GO:0030334 289 0.011
innate immune response GO:0045087 178 0.011
segmentation GO:0035282 4 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
Yeast
ras protein signal transduction GO:0007265 73 0.010
regulation of glucocorticoid receptor signaling pathway GO:2000322 2 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
generation of neurons GO:0048699 152 0.010

DDX5 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.041
nervous system disease DOID:863 431 0.041
neurodegenerative disease DOID:1289 102 0.037
musculoskeletal system disease DOID:17 223 0.036
myopathy DOID:423 104 0.034
muscular disease DOID:0080000 114 0.034
muscle tissue disease DOID:66 113 0.034
sensory system disease DOID:0050155 203 0.015
eye and adnexa disease DOID:1492 150 0.015