Homo sapiens

127 known processes

DIS3

DIS3 mitotic control homolog (S. cerevisiae)

(Aliases: dis3p,EXOSC11,KIAA1008,FLJ10484,MGC33035,RRP44,bA555G22.1,RP11-342J4.3,DKFZp667L1817)

DIS3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear transcribed mrna catabolic process exonucleolytic GO:0000291 7 0.949
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.808
rna catabolic process GO:0006401 71 0.689
ncrna catabolic process GO:0034661 14 0.667
maturation of 5 8s rrna GO:0000460 8 0.636
rna phosphodiester bond hydrolysis GO:0090501 35 0.574
mrna catabolic process GO:0006402 56 0.531
nuclear rna surveillance GO:0071027 4 0.517
exonucleolytic nuclear transcribed mrna catabolic process involved in deadenylation dependent decay GO:0043928 6 0.504
trna catabolic process GO:0016078 1 0.445
ribonucleoprotein complex biogenesis GO:0022613 116 0.445
cellular macromolecule catabolic process GO:0044265 380 0.404
multicellular organismal aging GO:0010259 3 0.349
post embryonic development GO:0009791 2 0.336
ribosome biogenesis GO:0042254 48 0.335
rrna metabolic process GO:0016072 40 0.327
nuclear ncrna surveillance GO:0071029 2 0.313
determination of adult lifespan GO:0008340 2 0.290
ncrna metabolic process GO:0034660 108 0.264
polyadenylation dependent rna catabolic process GO:0043633 3 0.260
modification dependent macromolecule catabolic process GO:0043632 212 0.247
nuclear transcribed mrna catabolic process GO:0000956 48 0.245
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.240
ncrna processing GO:0034470 83 0.218
nuclear polyadenylation dependent rrna catabolic process GO:0071035 2 0.215
dna catabolic process GO:0006308 49 0.201
dna deamination GO:0045006 9 0.197
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.147
nuclear polyadenylation dependent ncrna catabolic process GO:0071046 2 0.147
dna catabolic process endonucleolytic GO:0000737 37 0.136
trna metabolic process GO:0006399 35 0.136
polyadenylation dependent mrna catabolic process GO:0071047 1 0.122
rrna catabolic process GO:0016075 6 0.110
nucleoside phosphate catabolic process GO:1901292 412 0.105
defense response to other organism GO:0098542 129 0.099
neuronal action potential GO:0019228 9 0.096
ncrna 3 end processing GO:0043628 4 0.094
vesicle mediated transport GO:0016192 371 0.094
rrna processing GO:0006364 35 0.090
system process GO:0003008 349 0.089
rna 3 end processing GO:0031123 35 0.087
rna surveillance GO:0071025 5 0.086
positive regulation of catabolic process GO:0009896 310 0.083
action potential GO:0001508 34 0.083
polyadenylation dependent ncrna catabolic process GO:0043634 2 0.080
growth GO:0040007 202 0.079
positive regulation of cellular catabolic process GO:0031331 284 0.079
neurological system process GO:0050877 163 0.076
brain development GO:0007420 97 0.075
guanosine containing compound metabolic process GO:1901068 244 0.075
dosage compensation GO:0007549 3 0.074
rna processing GO:0006396 255 0.073
nervous system development GO:0007399 293 0.067
cut metabolic process GO:0071043 3 0.066
cellular component disassembly GO:0022411 92 0.064
response to external biotic stimulus GO:0043207 261 0.063
transmission of nerve impulse GO:0019226 11 0.058
snrna metabolic process GO:0016073 15 0.053
regulation of cellular amine metabolic process GO:0033238 11 0.051
endocytosis GO:0006897 159 0.051
response to biotic stimulus GO:0009607 276 0.051
organophosphate catabolic process GO:0046434 430 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.048
regulation of gene expression epigenetic GO:0040029 73 0.046
head development GO:0060322 108 0.043
nuclear polyadenylation dependent mrna catabolic process GO:0071042 1 0.043
nuclear mrna surveillance GO:0071028 4 0.042
purine nucleoside triphosphate catabolic process GO:0009146 392 0.041
execution phase of apoptosis GO:0097194 32 0.040
regulation of growth GO:0040008 165 0.040
cell growth GO:0016049 160 0.039
response to other organism GO:0051707 261 0.039
cellular amine metabolic process GO:0044106 41 0.037
histone mrna catabolic process GO:0071044 10 0.037
snrna processing GO:0016180 14 0.037
multicellular organismal signaling GO:0035637 34 0.034
regulation of meiotic cell cycle GO:0051445 4 0.034
mitotic cell cycle GO:0000278 326 0.033
posttranscriptional regulation of gene expression GO:0010608 213 0.033
regulation of cellular ketone metabolic process GO:0010565 50 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.033
myelination GO:0042552 6 0.032
nucleotide catabolic process GO:0009166 408 0.031
negative regulation of phosphorus metabolic process GO:0010563 267 0.031
cellular amino acid metabolic process GO:0006520 116 0.031
negative regulation of phosphate metabolic process GO:0045936 267 0.029
cellular ketone metabolic process GO:0042180 80 0.029
regulation of membrane potential GO:0042391 95 0.027
ribonucleoside catabolic process GO:0042454 406 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
defense response GO:0006952 315 0.024
neuromuscular junction development GO:0007528 3 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
amine metabolic process GO:0009308 44 0.023
purine nucleoside catabolic process GO:0006152 398 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
response to abiotic stimulus GO:0009628 336 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
mrna metabolic process GO:0016071 175 0.020
axon ensheathment GO:0008366 6 0.020
regeneration GO:0031099 4 0.020
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
rna interference GO:0016246 4 0.019
central nervous system development GO:0007417 123 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
protein catabolic process GO:0030163 325 0.019
gtp metabolic process GO:0046039 239 0.019
single organism cellular localization GO:1902580 332 0.019
phagocytosis GO:0006909 42 0.019
cut catabolic process GO:0071034 3 0.018
protein localization to organelle GO:0033365 280 0.018
positive regulation of cell growth GO:0030307 48 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
negative regulation of phosphatase activity GO:0010923 61 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
regulation of meiosis GO:0040020 3 0.017
apoptotic dna fragmentation GO:0006309 6 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
cell development GO:0048468 328 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
regulation of proteolysis GO:0030162 293 0.017
regulation of dna metabolic process GO:0051052 153 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
protein deubiquitination GO:0016579 79 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
immune response GO:0006955 307 0.015
regulation of cellular response to stress GO:0080135 244 0.015
tissue regeneration GO:0042246 3 0.015
oogenesis GO:0048477 2 0.015
positive regulation of hydrolase activity GO:0051345 331 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
cytoplasmic transport GO:0016482 379 0.014
positive regulation of transport GO:0051050 336 0.014
chromatin modification GO:0016568 298 0.014
regulation of cell cycle GO:0051726 393 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
negative regulation of growth GO:0045926 97 0.014
hindbrain development GO:0030902 3 0.014
negative regulation of cell death GO:0060548 345 0.014
ion homeostasis GO:0050801 230 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
maintenance of location GO:0051235 112 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
protein oligomerization GO:0051259 173 0.013
locomotory behavior GO:0007626 1 0.013
cellular protein catabolic process GO:0044257 261 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
histone modification GO:0016570 251 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
regulation of cell division GO:0051302 116 0.013
actin filament based process GO:0030029 224 0.012
regulation of protein stability GO:0031647 87 0.012
purine containing compound catabolic process GO:0072523 411 0.012
negative regulation of protein metabolic process GO:0051248 391 0.012
snorna metabolic process GO:0016074 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
covalent chromatin modification GO:0016569 254 0.012
protein modification by small protein removal GO:0070646 92 0.012
protein ubiquitination GO:0016567 314 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
regulation of cell cycle process GO:0010564 266 0.012
single organism membrane organization GO:0044802 268 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
protein maturation GO:0051604 233 0.012
mitotic cell cycle process GO:1903047 286 0.012
receptor mediated endocytosis GO:0006898 84 0.012
embryo development GO:0009790 123 0.012
immune effector process GO:0002252 159 0.012
chemical homeostasis GO:0048878 306 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
dephosphorylation GO:0016311 209 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
nucleoside catabolic process GO:0009164 408 0.011
negative regulation of protein modification process GO:0031400 200 0.011
innate immune response GO:0045087 178 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
cellular component disassembly involved in execution phase of apoptosis GO:0006921 13 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
cell division GO:0051301 168 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
apoptotic nuclear changes GO:0030262 13 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
regulation of phosphatase activity GO:0010921 81 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
memory GO:0007613 3 0.011
regulation of gtpase activity GO:0043087 180 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
cellular ion homeostasis GO:0006873 168 0.010
wound healing GO:0042060 115 0.010
cellular component morphogenesis GO:0032989 314 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
golgi vesicle transport GO:0048193 80 0.010
segmentation GO:0035282 4 0.010
transmembrane transport GO:0055085 399 0.010
regulation of establishment of protein localization GO:0070201 242 0.010

DIS3 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
sensory system disease DOID:0050155 203 0.012
nervous system disease DOID:863 431 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
organ system cancer DOID:0050686 164 0.012
musculoskeletal system disease DOID:17 223 0.012
bone disease DOID:0080001 88 0.010
connective tissue disease DOID:65 109 0.010