Homo sapiens

34 known processes

DIS3L

DIS3 mitotic control homolog (S. cerevisiae)-like

(Aliases: FLJ38088,MGC4562,KIAA1955)

DIS3L biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
snrna metabolic process GO:0016073 15 1.000
nuclear transcribed mrna catabolic process exonucleolytic GO:0000291 7 1.000
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 1.000
maturation of 5 8s rrna GO:0000460 8 0.991
rrna catabolic process GO:0016075 6 0.987
nuclear rna surveillance GO:0071027 4 0.986
nuclear polyadenylation dependent ncrna catabolic process GO:0071046 2 0.986
trna catabolic process GO:0016078 1 0.985
rna phosphodiester bond hydrolysis GO:0090501 35 0.984
ncrna metabolic process GO:0034660 108 0.982
exonucleolytic nuclear transcribed mrna catabolic process involved in deadenylation dependent decay GO:0043928 6 0.971
ncrna catabolic process GO:0034661 14 0.969
nuclear ncrna surveillance GO:0071029 2 0.969
polyadenylation dependent rna catabolic process GO:0043633 3 0.956
trna metabolic process GO:0006399 35 0.941
nuclear polyadenylation dependent rrna catabolic process GO:0071035 2 0.941
nuclear transcribed mrna catabolic process GO:0000956 48 0.940
mrna catabolic process GO:0006402 56 0.928
cellular macromolecule catabolic process GO:0044265 380 0.924
ncrna processing GO:0034470 83 0.911
rrna metabolic process GO:0016072 40 0.885
ncrna 3 end processing GO:0043628 4 0.877
snrna processing GO:0016180 14 0.859
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.846
intracellular mrna localization GO:0008298 1 0.843
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.821
polyadenylation dependent ncrna catabolic process GO:0043634 2 0.807
rna 3 end processing GO:0031123 35 0.806
rna catabolic process GO:0006401 71 0.795
dna deamination GO:0045006 9 0.719
rna surveillance GO:0071025 5 0.676
modification dependent macromolecule catabolic process GO:0043632 212 0.648
nuclear mrna surveillance GO:0071028 4 0.636
rna processing GO:0006396 255 0.635
ribonucleoprotein complex biogenesis GO:0022613 116 0.501
ribosome biogenesis GO:0042254 48 0.481
rrna processing GO:0006364 35 0.470
post embryonic development GO:0009791 2 0.465
mrna metabolic process GO:0016071 175 0.455
dna modification GO:0006304 27 0.291
response to other organism GO:0051707 261 0.278
multicellular organismal aging GO:0010259 3 0.216
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.185
histone mrna metabolic process GO:0008334 13 0.185
dna catabolic process endonucleolytic GO:0000737 37 0.149
regulation of cell growth GO:0001558 135 0.144
defense response to other organism GO:0098542 129 0.135
growth GO:0040007 202 0.121
determination of adult lifespan GO:0008340 2 0.106
response to external biotic stimulus GO:0043207 261 0.105
positive regulation of cell growth GO:0030307 48 0.093
locomotory behavior GO:0007626 1 0.091
cell growth GO:0016049 160 0.077
cut metabolic process GO:0071043 3 0.076
Human
defense response GO:0006952 315 0.067
regulation of growth GO:0040008 165 0.063
endocytosis GO:0006897 159 0.062
adult locomotory behavior GO:0008344 1 0.056
vesicle mediated transport GO:0016192 371 0.055
snorna metabolic process GO:0016074 1 0.051
neurological system process GO:0050877 163 0.051
spinal cord development GO:0021510 4 0.050
cellular amino acid metabolic process GO:0006520 116 0.048
response to virus GO:0009615 126 0.048
response to biotic stimulus GO:0009607 276 0.044
positive regulation of growth GO:0045927 58 0.044
nervous system development GO:0007399 293 0.044
defense response to virus GO:0051607 71 0.044
cellular component disassembly GO:0022411 92 0.043
positive regulation of catabolic process GO:0009896 310 0.043
Human
polyadenylation dependent mrna catabolic process GO:0071047 1 0.042
regeneration GO:0031099 4 0.039
snrna 3 end processing GO:0034472 1 0.038
system process GO:0003008 349 0.034
gtp metabolic process GO:0046039 239 0.034
Human
cellular ketone metabolic process GO:0042180 80 0.032
guanosine containing compound metabolic process GO:1901068 244 0.030
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
neuronal action potential GO:0019228 9 0.028
covalent chromatin modification GO:0016569 254 0.028
cut catabolic process GO:0071034 3 0.028
Human
positive regulation of immune system process GO:0002684 283 0.027
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.026
nucleoside triphosphate catabolic process GO:0009143 394 0.026
Human
head development GO:0060322 108 0.025
mitochondrion organization GO:0007005 156 0.025
dna catabolic process GO:0006308 49 0.025
protein maturation GO:0051604 233 0.024
ribonucleoside catabolic process GO:0042454 406 0.023
Human
positive regulation of immune response GO:0050778 159 0.023
positive regulation of hydrolase activity GO:0051345 331 0.023
Human
rna interference GO:0016246 4 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
nuclear polyadenylation dependent mrna catabolic process GO:0071042 1 0.022
mitotic cell cycle phase transition GO:0044772 162 0.022
organophosphate catabolic process GO:0046434 430 0.022
Human
organic acid catabolic process GO:0016054 71 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
execution phase of apoptosis GO:0097194 32 0.021
histone modification GO:0016570 251 0.020
anatomical structure homeostasis GO:0060249 100 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.020
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
Human
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
Human
cytoplasmic transport GO:0016482 379 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
Human
positive regulation of dna metabolic process GO:0051054 73 0.020
positive regulation of transport GO:0051050 336 0.019
single organism cellular localization GO:1902580 332 0.019
cell differentiation in spinal cord GO:0021515 1 0.019
regulation of membrane potential GO:0042391 95 0.019
regulation of protein localization GO:0032880 296 0.019
immune effector process GO:0002252 159 0.018
tissue regeneration GO:0042246 3 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
regulation of protein transport GO:0051223 213 0.018
amine metabolic process GO:0009308 44 0.017
regulation of establishment of protein localization GO:0070201 242 0.016
immune response GO:0006955 307 0.016
defense response to bacterium GO:0042742 63 0.016
homeostasis of number of cells GO:0048872 40 0.016
neuromuscular junction development GO:0007528 3 0.016
segmentation GO:0035282 4 0.015
nucleotide catabolic process GO:0009166 408 0.015
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
Human
axon ensheathment GO:0008366 6 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
Human
cellular protein catabolic process GO:0044257 261 0.015
regulation of immune response GO:0050776 201 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.014
translation GO:0006412 132 0.014
chromatin modification GO:0016568 298 0.014
lipid metabolic process GO:0006629 381 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
action potential GO:0001508 34 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.014
protein ubiquitination GO:0016567 314 0.014
chemical homeostasis GO:0048878 306 0.014
regulation of cellular response to stress GO:0080135 244 0.014
cellular amine metabolic process GO:0044106 41 0.013
positive regulation of innate immune response GO:0045089 79 0.013
rna splicing GO:0008380 131 0.013
mitotic cell cycle GO:0000278 326 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
response to abiotic stimulus GO:0009628 336 0.013
neurogenesis GO:0022008 169 0.013
transmembrane transport GO:0055085 399 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
meiotic chromosome segregation GO:0045132 4 0.013
regulation of cell cycle GO:0051726 393 0.013
blastoderm segmentation GO:0007350 2 0.013
compound eye development GO:0048749 1 0.013
anterior posterior axis specification GO:0009948 2 0.013
receptor mediated endocytosis GO:0006898 84 0.012
regulation of transferase activity GO:0051338 355 0.012
regulation of defense response GO:0031347 154 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
transmission of nerve impulse GO:0019226 11 0.012
protein alkylation GO:0008213 74 0.012
protein catabolic process GO:0030163 325 0.012
multicellular organismal homeostasis GO:0048871 67 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
Human
protein targeting GO:0006605 187 0.012
regulation of proteolysis GO:0030162 293 0.012
histone methylation GO:0016571 60 0.012
trna processing GO:0008033 23 0.012
positive regulation of defense response GO:0031349 87 0.012
tissue homeostasis GO:0001894 63 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
apoptotic dna fragmentation GO:0006309 6 0.011
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.011
wound healing GO:0042060 115 0.011
negative regulation of protein modification process GO:0031400 200 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
innate immune response GO:0045087 178 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
Human
cellular component disassembly involved in execution phase of apoptosis GO:0006921 13 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
Human
mitochondrial respiratory chain complex assembly GO:0033108 23 0.011
protein localization to organelle GO:0033365 280 0.011
dephosphorylation GO:0016311 209 0.011
regulation of intracellular transport GO:0032386 195 0.011
cytokine production GO:0001816 247 0.011
peripheral nervous system development GO:0007422 2 0.011
secretion GO:0046903 254 0.011
regulation of dna metabolic process GO:0051052 153 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.010
Human
secretion by cell GO:0032940 226 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010
Human
regulation of cell cycle process GO:0010564 266 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
actin mediated cell contraction GO:0070252 12 0.010
modification dependent protein catabolic process GO:0019941 209 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
single organism carbohydrate metabolic process GO:0044723 193 0.010
response to radiation GO:0009314 151 0.010

DIS3L disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.093
nervous system disease DOID:863 431 0.093
neurodegenerative disease DOID:1289 102 0.062
synucleinopathy DOID:0050890 22 0.017
musculoskeletal system disease DOID:17 223 0.017
disease of metabolism DOID:0014667 295 0.015
inherited metabolic disorder DOID:655 242 0.015
parkinson s disease DOID:14330 18 0.013
sensory system disease DOID:0050155 203 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.011
myopathy DOID:423 104 0.010
cancer DOID:162 167 0.010
disease of cellular proliferation DOID:14566 174 0.010
retinal disease DOID:5679 118 0.010
retinal degeneration DOID:8466 89 0.010