Homo sapiens

192 known processes

DNM1L

dynamin 1-like

(Aliases: FLJ41912,DLP1,HDYNIV,DRP1,DVLP,DYNIV-11,DYMPLE,VPS1)

DNM1L biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrial fission GO:0000266 14 1.000
positive regulation of protein targeting to membrane GO:0090314 8 0.990
mitochondrion organization GO:0007005 156 0.944
positive regulation of mitochondrial fission GO:0090141 7 0.934
regulation of mitochondrial fission GO:0090140 8 0.880
single organism cellular localization GO:1902580 332 0.839
positive regulation of intracellular protein transport GO:0090316 76 0.838
positive regulation of organelle organization GO:0010638 195 0.831
positive regulation of developmental process GO:0051094 314 0.772
positive regulation of cellular component organization GO:0051130 376 0.767
membrane organization GO:0061024 292 0.737
positive regulation of mitochondrion organization GO:0010822 30 0.737
intracellular protein transport GO:0006886 270 0.704
protein targeting GO:0006605 187 0.687
regulation of anatomical structure morphogenesis GO:0022603 286 0.684
regulation of establishment of protein localization GO:0070201 242 0.630
positive regulation of intracellular transport GO:0032388 104 0.626
establishment of protein localization to membrane GO:0090150 121 0.610
regulation of protein transport GO:0051223 213 0.604
regulation of protein localization GO:0032880 296 0.548
positive regulation of transport GO:0051050 336 0.492
single organism membrane organization GO:0044802 268 0.482
regulation of intracellular protein transport GO:0033157 123 0.429
regulation of intracellular transport GO:0032386 195 0.427
regulation of protein targeting GO:1903533 91 0.419
organelle fission GO:0048285 149 0.409
regulation of protein oligomerization GO:0032459 26 0.316
positive regulation of protein transport GO:0051222 135 0.316
post embryonic development GO:0009791 2 0.214
regulation of cellular component biogenesis GO:0044087 281 0.182
establishment of protein localization to mitochondrion GO:0072655 22 0.161
protein homooligomerization GO:0051260 100 0.160
female gamete generation GO:0007292 2 0.154
protein targeting to membrane GO:0006612 42 0.133
microtubule based process GO:0007017 210 0.131
locomotory behavior GO:0007626 1 0.129
cytoplasmic transport GO:0016482 379 0.122
positive regulation of protein complex assembly GO:0031334 86 0.121
positive regulation of cellular component biogenesis GO:0044089 158 0.113
protein oligomerization GO:0051259 173 0.107
establishment of protein localization to organelle GO:0072594 172 0.102
protein modification by small protein conjugation GO:0032446 342 0.099
protein localization to mitochondrion GO:0070585 25 0.097
Mouse
oogenesis GO:0048477 2 0.089
protein catabolic process GO:0030163 325 0.086
protein localization to organelle GO:0033365 280 0.084
Mouse
determination of adult lifespan GO:0008340 2 0.082
Worm
positive regulation of protein oligomerization GO:0032461 17 0.082
transmembrane transport GO:0055085 399 0.081
cellular protein catabolic process GO:0044257 261 0.081
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.080
multicellular organismal aging GO:0010259 3 0.077
Worm
ras protein signal transduction GO:0007265 73 0.070
regulation of cell cycle GO:0051726 393 0.068
mitotic cell cycle GO:0000278 326 0.068
microtubule cytoskeleton organization GO:0000226 176 0.066
actin filament based process GO:0030029 224 0.065
protein processing GO:0016485 226 0.063
posttranscriptional regulation of gene expression GO:0010608 213 0.059
amine metabolic process GO:0009308 44 0.056
positive regulation of phosphorylation GO:0042327 394 0.054
vesicle mediated transport GO:0016192 371 0.054
negative regulation of protein metabolic process GO:0051248 391 0.048
positive regulation of programmed cell death GO:0043068 249 0.047
mitochondrial transport GO:0006839 60 0.047
rna interference GO:0016246 4 0.046
regulation of translation GO:0006417 89 0.046
embryo development GO:0009790 123 0.046
Worm
regulation of protein serine threonine kinase activity GO:0071900 179 0.046
mitotic cell cycle process GO:1903047 286 0.045
positive regulation of cell death GO:0010942 263 0.045
nucleoside catabolic process GO:0009164 408 0.045
cellular macromolecule catabolic process GO:0044265 380 0.045
secretion by cell GO:0032940 226 0.044
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
ubiquitin dependent protein catabolic process GO:0006511 206 0.043
regulation of cellular amine metabolic process GO:0033238 11 0.043
small gtpase mediated signal transduction GO:0007264 78 0.043
cation transmembrane transport GO:0098655 238 0.043
positive regulation of apoptotic process GO:0043065 246 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.040
cellular amino acid metabolic process GO:0006520 116 0.039
negative regulation of apoptotic process GO:0043066 316 0.039
single organism carbohydrate metabolic process GO:0044723 193 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.038
endocytosis GO:0006897 159 0.038
protein localization to membrane GO:0072657 160 0.038
system process GO:0003008 349 0.037
protein maturation GO:0051604 233 0.037
single organism reproductive process GO:0044702 98 0.037
positive regulation of transferase activity GO:0051347 227 0.037
translation GO:0006412 132 0.036
defense response GO:0006952 315 0.035
cell development GO:0048468 328 0.035
negative regulation of programmed cell death GO:0043069 321 0.035
signal transduction by phosphorylation GO:0023014 297 0.035
adult locomotory behavior GO:0008344 1 0.034
regulation of cytokine production GO:0001817 232 0.034
negative regulation of catalytic activity GO:0043086 335 0.034
regulation of protein complex assembly GO:0043254 147 0.033
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
cellular lipid metabolic process GO:0044255 303 0.033
photoreceptor cell differentiation GO:0046530 2 0.033
behavior GO:0007610 112 0.033
response to cytokine GO:0034097 232 0.032
neuromuscular junction development GO:0007528 3 0.032
cellular cation homeostasis GO:0030003 163 0.032
mitotic cell cycle phase transition GO:0044772 162 0.032
chemotaxis GO:0006935 157 0.032
cellular amine metabolic process GO:0044106 41 0.031
maintenance of location GO:0051235 112 0.031
negative regulation of cell death GO:0060548 345 0.030
response to abiotic stimulus GO:0009628 336 0.030
negative regulation of phosphate metabolic process GO:0045936 267 0.030
response to external biotic stimulus GO:0043207 261 0.029
negative regulation of phosphorus metabolic process GO:0010563 267 0.029
cellular ketone metabolic process GO:0042180 80 0.029
regulation of kinase activity GO:0043549 314 0.028
ribonucleotide catabolic process GO:0009261 405 0.028
regulation of transferase activity GO:0051338 355 0.028
nervous system development GO:0007399 293 0.028
microtubule polymerization or depolymerization GO:0031109 37 0.027
mapk cascade GO:0000165 288 0.027
cell projection organization GO:0030030 252 0.027
regulation of mitotic cell cycle GO:0007346 189 0.027
oocyte development GO:0048599 1 0.027
innate immune response GO:0045087 178 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
dephosphorylation GO:0016311 209 0.026
engulfment of apoptotic cell GO:0043652 2 0.026
lipid biosynthetic process GO:0008610 177 0.025
modification dependent protein catabolic process GO:0019941 209 0.025
dendritic spine morphogenesis GO:0060997 3 0.025
negative regulation of catabolic process GO:0009895 104 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
cellular response to cytokine stimulus GO:0071345 181 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
negative regulation of intracellular signal transduction GO:1902532 183 0.024
negative regulation of protein processing GO:0010955 142 0.024
lipid metabolic process GO:0006629 381 0.024
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.024
oocyte differentiation GO:0009994 2 0.024
regulation of cell cycle process GO:0010564 266 0.024
tripartite regional subdivision GO:0007351 2 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
cell morphogenesis GO:0000902 296 0.023
immune response GO:0006955 307 0.023
neuron development GO:0048666 113 0.023
taxis GO:0042330 157 0.023
nls bearing protein import into nucleus GO:0006607 2 0.023
meiosis i GO:0007127 4 0.023
regulation of locomotion GO:0040012 329 0.023
regulation of protein maturation GO:1903317 150 0.023
protein modification by small protein removal GO:0070646 92 0.023
receptor mediated endocytosis GO:0006898 84 0.022
anterior posterior axis specification GO:0009948 2 0.022
immune effector process GO:0002252 159 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
nuclear transport GO:0051169 179 0.022
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.022
positive regulation of peptidase activity GO:0010952 88 0.022
regulation of cell differentiation GO:0045595 393 0.021
embryo development ending in birth or egg hatching GO:0009792 34 0.021
Worm
nucleobase containing compound transport GO:0015931 51 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
positive regulation of endopeptidase activity GO:0010950 84 0.020
cilium organization GO:0044782 68 0.020
regulation of cellular ketone metabolic process GO:0010565 50 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
regulation of peptidase activity GO:0052547 180 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
cellular homeostasis GO:0019725 196 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
gtp metabolic process GO:0046039 239 0.019
nitrogen compound transport GO:0071705 191 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
protein import GO:0017038 130 0.019
protein targeting to nucleus GO:0044744 104 0.019
anion transport GO:0006820 161 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
developmental growth GO:0048589 48 0.019
cell type specific apoptotic process GO:0097285 125 0.019
cell cycle phase transition GO:0044770 173 0.018
nuclear export GO:0051168 69 0.018
spindle organization GO:0007051 53 0.018
positive regulation of cell differentiation GO:0045597 211 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
response to nitrogen compound GO:1901698 184 0.018
tissue regeneration GO:0042246 3 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
meiotic chromosome segregation GO:0045132 4 0.018
mitochondrion distribution GO:0048311 3 0.018
regulation of proteolysis GO:0030162 293 0.018
positive regulation of kinase activity GO:0033674 204 0.018
macromolecular complex disassembly GO:0032984 60 0.017
reproductive system development GO:0061458 56 0.017
regulation of membrane potential GO:0042391 95 0.017
regulation of map kinase activity GO:0043405 108 0.017
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
mitotic nuclear division GO:0007067 119 0.017
microtubule polymerization GO:0046785 18 0.017
spermatid development GO:0007286 4 0.017
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
cellular protein complex assembly GO:0043623 188 0.017
endomembrane system organization GO:0010256 196 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
nuclear import GO:0051170 106 0.017
reactive oxygen species metabolic process GO:0072593 75 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
nuclear division GO:0000280 128 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
regulation of protein kinase activity GO:0045859 289 0.016
head development GO:0060322 108 0.016
protein folding GO:0006457 38 0.016
regulation of immune response GO:0050776 201 0.016
neuron differentiation GO:0030182 138 0.016
cell cycle g2 m phase transition GO:0044839 43 0.016
cell part morphogenesis GO:0032990 137 0.016
purine containing compound catabolic process GO:0072523 411 0.016
negative regulation of cell cycle process GO:0010948 121 0.016
blastoderm segmentation GO:0007350 2 0.016
segmentation GO:0035282 4 0.016
muscle system process GO:0003012 81 0.016
regulation of meiotic cell cycle GO:0051445 4 0.016
apoptotic mitochondrial changes GO:0008637 57 0.016
peptidyl serine phosphorylation GO:0018105 101 0.016
regulation of ras protein signal transduction GO:0046578 155 0.016
response to organic cyclic compound GO:0014070 204 0.016
acetyl coa metabolic process GO:0006084 8 0.016
negative regulation of protein modification process GO:0031400 200 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
ncrna metabolic process GO:0034660 108 0.015
protein targeting to mitochondrion GO:0006626 19 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
nucleotide catabolic process GO:0009166 408 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
cell cell signaling GO:0007267 155 0.015
lipid localization GO:0010876 106 0.015
positive regulation of catabolic process GO:0009896 310 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.015
cation transport GO:0006812 331 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
negative regulation of proteolysis GO:0045861 132 0.015
intracellular mrna localization GO:0008298 1 0.015
sleep GO:0030431 2 0.015
regulation of neuron death GO:1901214 56 0.015
epithelium development GO:0060429 227 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
reproduction GO:0000003 63 0.014
rna localization GO:0006403 41 0.014
regulation of dna metabolic process GO:0051052 153 0.014
protein localization to nucleus GO:0034504 136 0.014
muscle structure development GO:0061061 98 0.014
aging GO:0007568 66 0.014
Worm
cellular divalent inorganic cation homeostasis GO:0072503 128 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
cation homeostasis GO:0055080 189 0.014
coenzyme metabolic process GO:0006732 65 0.014
organelle assembly GO:0070925 176 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
regulation of protein processing GO:0070613 150 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.014
hippocampus development GO:0021766 1 0.014
apoptotic signaling pathway GO:0097190 268 0.014
neurogenesis GO:0022008 169 0.014
protein polyubiquitination GO:0000209 110 0.014
reproductive structure development GO:0048608 55 0.014
chemical homeostasis GO:0048878 306 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
regulation of mapk cascade GO:0043408 262 0.013
development of primary sexual characteristics GO:0045137 35 0.013
cell aging GO:0007569 52 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
regeneration GO:0031099 4 0.013
negative regulation of developmental process GO:0051093 247 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
regulation of response to dna damage stimulus GO:2001020 94 0.013
regulation of cellular response to stress GO:0080135 244 0.013
oxidation reduction process GO:0055114 396 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.013
cell cycle checkpoint GO:0000075 117 0.013
actin filament based movement GO:0030048 17 0.012
divalent inorganic cation transport GO:0072511 158 0.012
regulation of response to external stimulus GO:0032101 222 0.012
myosin filament organization GO:0031033 2 0.012
spermatid differentiation GO:0048515 4 0.012
calcium ion transport GO:0006816 147 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
response to other organism GO:0051707 261 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
regulation of proteasomal protein catabolic process GO:0061136 87 0.012
reproductive process GO:0022414 106 0.012
neurological system process GO:0050877 163 0.012
microtubule organizing center organization GO:0031023 62 0.012
generation of neurons GO:0048699 152 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
ion homeostasis GO:0050801 230 0.012
response to extracellular stimulus GO:0009991 85 0.012
organelle localization GO:0051640 84 0.012
protein autophosphorylation GO:0046777 123 0.012
lymphocyte activation GO:0046649 133 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
response to wounding GO:0009611 168 0.011
cellular ion homeostasis GO:0006873 168 0.011
positive regulation of proteolysis GO:0045862 142 0.011
developmental process involved in reproduction GO:0003006 66 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
response to radiation GO:0009314 151 0.011
protein ubiquitination GO:0016567 314 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
cell projection morphogenesis GO:0048858 129 0.011
peripheral nervous system development GO:0007422 2 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
actin mediated cell contraction GO:0070252 12 0.011
positive regulation of cytoplasmic transport GO:1903651 82 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
snrna metabolic process GO:0016073 15 0.011
rna transport GO:0050658 39 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
metal ion transport GO:0030001 272 0.011
cytokine production GO:0001816 247 0.011
cellular amide metabolic process GO:0043603 69 0.011
potassium ion transport GO:0006813 62 0.011
purine nucleoside catabolic process GO:0006152 398 0.010
neuron death GO:0070997 65 0.010
regulation of defense response GO:0031347 154 0.010
establishment or maintenance of cell polarity GO:0007163 31 0.010
muscle cell differentiation GO:0042692 63 0.010
regulation of cell migration GO:0030334 289 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
monosaccharide metabolic process GO:0005996 74 0.010
stress activated protein kinase signaling cascade GO:0031098 94 0.010
circulatory system process GO:0003013 113 0.010
ribonucleoprotein complex subunit organization GO:0071826 81 0.010
response to virus GO:0009615 126 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
positive regulation of secretion GO:0051047 116 0.010
g2 m transition of mitotic cell cycle GO:0000086 41 0.010
chromosome segregation GO:0007059 114 0.010
positive regulation of innate immune response GO:0045089 79 0.010
purine nucleoside triphosphate catabolic process GO:0009146 392 0.010
peptidyl serine modification GO:0018209 106 0.010
response to growth factor GO:0070848 205 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
regulation of homeostatic process GO:0032844 121 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.010
single organism nuclear import GO:1902593 104 0.010
centrosome organization GO:0051297 58 0.010
regulation of protein catabolic process GO:0042176 155 0.010

DNM1L disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.024
nervous system disease DOID:863 431 0.024