Homo sapiens

59 known processes

DNM2

dynamin 2

(Aliases: DYNII,CMTDIB,DYN2,CMT2M,CMTDI1,DI-CMTB)

DNM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane tubulation GO:0097320 12 1.000
nucleoside triphosphate catabolic process GO:0009143 394 1.000
Worm
synaptic vesicle endocytosis GO:0048488 2 1.000
Fly
synaptic vesicle transport GO:0048489 5 1.000
Fly
guanosine containing compound catabolic process GO:1901069 239 0.999
Worm
gtp catabolic process GO:0006184 237 0.999
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.998
Worm
synaptic vesicle recycling GO:0036465 3 0.998
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.997
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.994
Worm
vesicle organization GO:0016050 62 0.993
Fly
nucleotide catabolic process GO:0009166 408 0.992
Worm
trivalent inorganic cation transport GO:0072512 4 0.992
nucleoside catabolic process GO:0009164 408 0.992
Worm
ribonucleoside catabolic process GO:0042454 406 0.991
Worm
nucleoside phosphate catabolic process GO:1901292 412 0.990
Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.990
actin filament organization GO:0007015 128 0.989
positive regulation of cellular catabolic process GO:0031331 284 0.989
purine nucleotide catabolic process GO:0006195 405 0.988
Worm
purine ribonucleoside metabolic process GO:0046128 437 0.988
Worm
membrane organization GO:0061024 292 0.988
purine ribonucleotide catabolic process GO:0009154 404 0.988
Worm
organophosphate catabolic process GO:0046434 430 0.987
Worm
ribonucleoside triphosphate catabolic process GO:0009203 391 0.986
Worm
gtp metabolic process GO:0046039 239 0.983
Worm
transferrin transport GO:0033572 4 0.983
actin filament based process GO:0030029 224 0.983
Fly
vesicle localization GO:0051648 26 0.981
Fly
purine ribonucleoside catabolic process GO:0046130 398 0.979
Worm
regulation of nucleotide metabolic process GO:0006140 269 0.979
establishment of vesicle localization GO:0051650 23 0.977
Fly
regulation of actin cytoskeleton organization GO:0032956 116 0.975
Fly
vesicle mediated transport GO:0016192 371 0.973
ferric iron transport GO:0015682 4 0.963
regulation of purine nucleotide catabolic process GO:0033121 205 0.960
endosome organization GO:0007032 20 0.958
Human
single organism membrane organization GO:0044802 268 0.955
regulation of nucleotide catabolic process GO:0030811 205 0.955
synaptic vesicle localization GO:0097479 5 0.954
Fly
regulation of cell differentiation GO:0045595 393 0.952
purine nucleoside triphosphate metabolic process GO:0009144 412 0.950
Worm
regulation of cellular component biogenesis GO:0044087 281 0.949
single organism membrane fusion GO:0044801 37 0.940
Yeast
purine nucleoside catabolic process GO:0006152 398 0.940
Worm
purine containing compound catabolic process GO:0072523 411 0.934
Worm
glycosyl compound catabolic process GO:1901658 413 0.929
Worm
ribonucleotide catabolic process GO:0009261 405 0.918
Worm
regulation of cytoskeleton organization GO:0051493 177 0.916
Fly
positive regulation of cellular component organization GO:0051130 376 0.915
organelle fusion GO:0048284 36 0.915
Yeast
positive regulation of nucleotide catabolic process GO:0030813 185 0.913
plasma membrane organization GO:0007009 115 0.908
regulation of purine nucleotide metabolic process GO:1900542 264 0.896
regulation of neuronal synaptic plasticity GO:0048168 1 0.894
Fly
regulation of gtp catabolic process GO:0033124 180 0.893
membrane budding GO:0006900 28 0.835
Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.832
Worm
regulation of gtpase activity GO:0043087 180 0.818
cellular protein complex assembly GO:0043623 188 0.818
membrane protein proteolysis GO:0033619 38 0.814
organelle localization GO:0051640 84 0.810
Fly
positive regulation of catabolic process GO:0009896 310 0.810
membrane fusion GO:0061025 43 0.809
Yeast
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.800
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.798
regulation of vesicle mediated transport GO:0060627 130 0.772
actin mediated cell contraction GO:0070252 12 0.766
establishment of organelle localization GO:0051656 59 0.760
Fly
actin cytoskeleton organization GO:0030036 207 0.755
Fly
response to salt stress GO:0009651 3 0.752
epithelium development GO:0060429 227 0.747
Fly
actin nucleation GO:0045010 21 0.733
ribonucleoside triphosphate metabolic process GO:0009199 412 0.732
Worm
positive regulation of gtpase activity GO:0043547 166 0.732
epithelial cell development GO:0002064 34 0.732
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.728
regulation of endocytosis GO:0030100 72 0.722
epithelial cell differentiation GO:0030855 141 0.686
Fly
adherens junction organization GO:0034332 36 0.684
Fly
negative regulation of cellular component organization GO:0051129 235 0.661
regulation of protein complex assembly GO:0043254 147 0.632
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.625
regulation of receptor mediated endocytosis GO:0048259 32 0.620
positive regulation of transport GO:0051050 336 0.614
short term memory GO:0007614 1 0.601
Fly
ras protein signal transduction GO:0007265 73 0.590
transition metal ion transport GO:0000041 23 0.587
regulation of arf protein signal transduction GO:0032012 1 0.572
clathrin mediated endocytosis GO:0072583 8 0.554
Fly
sensory perception GO:0007600 103 0.547
cellular response to endogenous stimulus GO:0071495 336 0.533
receptor mediated endocytosis GO:0006898 84 0.527
positive regulation of developmental process GO:0051094 314 0.508
positive regulation of gtp catabolic process GO:0033126 166 0.490
peptidyl tyrosine phosphorylation GO:0018108 170 0.489
pinocytosis GO:0006907 8 0.485
endocytosis GO:0006897 159 0.485
behavior GO:0007610 112 0.470
Fly
regulation of actin filament based process GO:0032970 141 0.453
Fly
positive regulation of cellular component biogenesis GO:0044089 158 0.442
positive regulation of protein oligomerization GO:0032461 17 0.427
cell cell signaling GO:0007267 155 0.421
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.412
single organism carbohydrate metabolic process GO:0044723 193 0.411
cellular response to nitrogen compound GO:1901699 144 0.411
spermatid development GO:0007286 4 0.405
Fly
positive regulation of rap gtpase activity GO:0032854 8 0.387
phagolysosome assembly GO:0001845 5 0.375
growth GO:0040007 202 0.371
Fly
actin filament based movement GO:0030048 17 0.367
guanosine containing compound metabolic process GO:1901068 244 0.358
Worm
positive regulation of phosphorylation GO:0042327 394 0.356
positive regulation of protein catabolic process GO:0045732 75 0.343
receptor metabolic process GO:0043112 81 0.335
regulation of membrane tubulation GO:1903525 2 0.312
phagosome lysosome fusion GO:0090385 4 0.308
positive regulation of endocytosis GO:0045807 42 0.305
morphogenesis of a polarized epithelium GO:0001738 3 0.303
Fly
endomembrane system organization GO:0010256 196 0.299
response to oxygen containing compound GO:1901700 369 0.295
positive regulation of protein polymerization GO:0032273 45 0.294
cytokinesis GO:0000910 96 0.289
Fly
cellular macromolecule catabolic process GO:0044265 380 0.278
cytoplasmic transport GO:0016482 379 0.266
small gtpase mediated signal transduction GO:0007264 78 0.259
cellular protein catabolic process GO:0044257 261 0.257
regulation of actin polymerization or depolymerization GO:0008064 56 0.256
regulation of protein polymerization GO:0032271 63 0.253
regulation of actin filament polymerization GO:0030833 50 0.249
sensory perception of sound GO:0007605 37 0.248
sex determination GO:0007530 3 0.246
regulation of protein catabolic process GO:0042176 155 0.238
dendritic spine maintenance GO:0097062 1 0.236
establishment of synaptic vesicle localization GO:0097480 5 0.234
Fly
regulation of membrane protein ectodomain proteolysis GO:0051043 17 0.230
positive regulation of nucleoside metabolic process GO:0045979 186 0.226
positive regulation of notch signaling pathway GO:0045747 6 0.221
Fly
adult locomotory behavior GO:0008344 1 0.219
regulation of synaptic plasticity GO:0048167 3 0.213
Fly
growth hormone receptor signaling pathway GO:0060396 10 0.212
sensory perception of mechanical stimulus GO:0050954 37 0.211
positive regulation of cytoskeleton organization GO:0051495 83 0.210
positive regulation of vascular endothelial growth factor signaling pathway GO:1900748 3 0.206
actin filament bundle organization GO:0061572 54 0.206
regulation of ras protein signal transduction GO:0046578 155 0.203
macropinocytosis GO:0044351 1 0.199
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.197
regulation of protein kinase activity GO:0045859 289 0.195
modification dependent protein catabolic process GO:0019941 209 0.194
locomotory behavior GO:0007626 1 0.188
positive regulation of protein complex assembly GO:0031334 86 0.187
neurological system process GO:0050877 163 0.187
Fly
myeloid cell differentiation GO:0030099 117 0.183
positive regulation of cell projection organization GO:0031346 64 0.183
ubiquitin dependent protein catabolic process GO:0006511 206 0.183
post embryonic development GO:0009791 2 0.180
Worm
single organism cellular localization GO:1902580 332 0.180
synaptic transmission GO:0007268 61 0.178
Fly
associative learning GO:0008306 1 0.175
Fly
protein targeting GO:0006605 187 0.175
sensory organ development GO:0007423 52 0.174
Fly
iron ion transport GO:0006826 12 0.173
retrograde transport endosome to golgi GO:0042147 45 0.171
metal ion transport GO:0030001 272 0.171
response to osmotic stress GO:0006970 17 0.170
regulation of pro b cell differentiation GO:2000973 1 0.168
receptor transactivation GO:0035624 4 0.167
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.164
protein polymerization GO:0051258 71 0.164
regulation of cellular amine metabolic process GO:0033238 11 0.163
protein oligomerization GO:0051259 173 0.163
system process GO:0003008 349 0.161
Fly
positive regulation of actin filament polymerization GO:0030838 38 0.161
caveola assembly GO:0070836 4 0.159
cation transport GO:0006812 331 0.159
cellular carbohydrate metabolic process GO:0044262 84 0.158
mitochondrion organization GO:0007005 156 0.154
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.152
organelle assembly GO:0070925 176 0.151
spermatid differentiation GO:0048515 4 0.149
Fly
peptidyl tyrosine modification GO:0018212 170 0.148
regulation of ras gtpase activity GO:0032318 128 0.148
regulation of notch signaling pathway GO:0008593 18 0.148
Fly
regulation of clathrin mediated endocytosis GO:2000369 4 0.148
positive regulation of cell development GO:0010720 92 0.145
glycerolipid metabolic process GO:0046486 107 0.142
cellular macromolecular complex assembly GO:0034622 324 0.141
regulation of growth GO:0040008 165 0.141
Fly
cytoskeleton dependent cytokinesis GO:0061640 22 0.139
Fly
regulation of rap protein signal transduction GO:0032487 9 0.138
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.138
regulation of neural precursor cell proliferation GO:2000177 4 0.138
positive regulation of locomotion GO:0040017 186 0.138
cell morphogenesis GO:0000902 296 0.136
negative regulation of cell proliferation GO:0008285 228 0.132
actin filament polymerization GO:0030041 45 0.128
monovalent inorganic cation transport GO:0015672 128 0.128
mitotic cell cycle process GO:1903047 286 0.128
Fly
cell projection organization GO:0030030 252 0.125
cilium organization GO:0044782 68 0.125
positive regulation of cell differentiation GO:0045597 211 0.123
regulation of small gtpase mediated signal transduction GO:0051056 156 0.123
protein localization to organelle GO:0033365 280 0.123
negative regulation of phosphorus metabolic process GO:0010563 267 0.120
response to cytokine GO:0034097 232 0.119
lung growth GO:0060437 2 0.116
g1 s transition of mitotic cell cycle GO:0000082 78 0.116
negative regulation of growth GO:0045926 97 0.116
toxin transport GO:1901998 4 0.115
mitotic cell cycle GO:0000278 326 0.115
Fly
positive regulation of kinase activity GO:0033674 204 0.115
chromatin modification GO:0016568 298 0.113
positive regulation of intracellular transport GO:0032388 104 0.108
regulation of cell migration GO:0030334 289 0.105
positive regulation of organelle organization GO:0010638 195 0.103
positive regulation of ras gtpase activity GO:0032320 117 0.101
negative regulation of hydrolase activity GO:0051346 182 0.101
protein localization to lysosome GO:0061462 11 0.100
salivary gland morphogenesis GO:0007435 4 0.099
Fly
glomerular visceral epithelial cell development GO:0072015 2 0.099
cellular response to hormone stimulus GO:0032870 125 0.097
phagocytosis engulfment GO:0006911 7 0.097
Worm
renal filtration cell differentiation GO:0061318 4 0.096
cellular ketone metabolic process GO:0042180 80 0.094
mitochondrial fusion GO:0008053 13 0.094
Yeast
hematopoietic or lymphoid organ development GO:0048534 186 0.092
immune system development GO:0002520 195 0.092
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.091
positive regulation of nucleotide metabolic process GO:0045981 230 0.091
growth of symbiont in host GO:0044117 1 0.089
atp metabolic process GO:0046034 176 0.087
regulation of anatomical structure size GO:0090066 101 0.085
interleukin 2 mediated signaling pathway GO:0038110 3 0.084
cellular response to peptide GO:1901653 59 0.082
regulation of cell substrate adhesion GO:0010810 68 0.081
lipid metabolic process GO:0006629 381 0.081
regulation of myeloid cell differentiation GO:0045637 81 0.080
cell chemotaxis GO:0060326 112 0.079
cilium morphogenesis GO:0060271 75 0.079
negative regulation of actin nucleation GO:0051126 3 0.077
response to tumor necrosis factor GO:0034612 76 0.076
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.076
regulation of protein oligomerization GO:0032459 26 0.076
positive regulation of clathrin mediated endocytosis GO:2000370 2 0.075
secretion GO:0046903 254 0.074
cell cycle phase transition GO:0044770 173 0.073
receptor internalization GO:0031623 43 0.073
positive regulation of membrane protein ectodomain proteolysis GO:0051044 13 0.072
positive regulation of cytoplasmic transport GO:1903651 82 0.071
rac protein signal transduction GO:0016601 12 0.070
tissue morphogenesis GO:0048729 96 0.070
Fly
response to abiotic stimulus GO:0009628 336 0.070
Fly
actin polymerization or depolymerization GO:0008154 56 0.070
cell cycle g1 s phase transition GO:0044843 80 0.070
negative regulation of protein metabolic process GO:0051248 391 0.069
cell cell junction organization GO:0045216 69 0.069
Fly
response to organonitrogen compound GO:0010243 156 0.068
golgi vesicle transport GO:0048193 80 0.067
regulation of protein localization GO:0032880 296 0.067
reproductive process GO:0022414 106 0.066
Worm Fly
response to heat GO:0009408 21 0.066
Fly
negative regulation of cell growth GO:0030308 83 0.066
membrane protein ectodomain proteolysis GO:0006509 33 0.066
growth involved in symbiotic interaction GO:0044110 2 0.066
carbohydrate metabolic process GO:0005975 207 0.065
cellular component maintenance GO:0043954 6 0.064
Fly
chromatin organization GO:0006325 351 0.063
protein catabolic process GO:0030163 325 0.063
Worm
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.062
protein localization to vacuole GO:0072665 11 0.062
regulation of nucleoside metabolic process GO:0009118 209 0.061
protein targeting to vacuole GO:0006623 8 0.061
vacuolar transport GO:0007034 34 0.059
response to growth factor GO:0070848 205 0.059
cellular amine metabolic process GO:0044106 41 0.058
intracellular protein transport GO:0006886 270 0.058
macromolecular complex disassembly GO:0032984 60 0.058
regulation of leukocyte proliferation GO:0070663 67 0.056
covalent chromatin modification GO:0016569 254 0.055
regulation of anatomical structure morphogenesis GO:0022603 286 0.054
positive regulation of cell adhesion GO:0045785 84 0.053
organic hydroxy compound metabolic process GO:1901615 147 0.052
actin filament bundle assembly GO:0051017 54 0.052
response to nutrient GO:0007584 20 0.051
Fly
regulation of cell activation GO:0050865 125 0.051
notch signaling pathway GO:0007219 31 0.051
Fly
histone modification GO:0016570 251 0.051
positive regulation of neuroblast proliferation GO:0002052 2 0.051
vesicle transport along actin filament GO:0030050 2 0.050
stress activated mapk cascade GO:0051403 93 0.049
regulation of multi organism process GO:0043900 157 0.048
regulation of embryonic development GO:0045995 20 0.048
memory GO:0007613 3 0.047
Fly
cellular component morphogenesis GO:0032989 314 0.047
Fly
positive regulation of cell proliferation GO:0008284 301 0.047
rna transport GO:0050658 39 0.047
regulation of actin filament bundle assembly GO:0032231 36 0.047
neurogenesis GO:0022008 169 0.047
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.047
lipid tube assembly GO:0060988 2 0.046
regulation of erk1 and erk2 cascade GO:0070372 99 0.046
response to peptide hormone GO:0043434 61 0.045
exosomal secretion GO:1990182 15 0.044
negative regulation of intracellular signal transduction GO:1902532 183 0.044
cellular response to growth factor stimulus GO:0071363 197 0.044
purine nucleoside monophosphate metabolic process GO:0009126 186 0.044
tube morphogenesis GO:0035239 95 0.043
nucleobase containing compound transport GO:0015931 51 0.043
epithelial cell morphogenesis GO:0003382 8 0.043
vesicle fusion GO:0006906 17 0.042
positive regulation of filopodium assembly GO:0051491 7 0.042
organelle inheritance GO:0048308 2 0.042
response to nitrogen compound GO:1901698 184 0.041
response to biotic stimulus GO:0009607 276 0.040
developmental process involved in reproduction GO:0003006 66 0.040
Worm Fly
filopodium assembly GO:0046847 18 0.040
rap protein signal transduction GO:0032486 7 0.040
regulation of cell motility GO:2000145 299 0.040
stress fiber assembly GO:0043149 40 0.039
tissue homeostasis GO:0001894 63 0.039
cell junction organization GO:0034330 79 0.039
Fly
regulation of cellular response to growth factor stimulus GO:0090287 76 0.039
embryo development GO:0009790 123 0.039
Worm
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.039
cell projection assembly GO:0030031 126 0.039
defense response to virus GO:0051607 71 0.038
ribonucleoside monophosphate metabolic process GO:0009161 187 0.038
regulation of filopodium assembly GO:0051489 13 0.037
plasma membrane raft assembly GO:0044854 4 0.037
circulatory system development GO:0072359 262 0.037
negative regulation of immune system process GO:0002683 136 0.037
establishment of protein localization to organelle GO:0072594 172 0.037
autophagic cell death GO:0048102 3 0.036
endosomal transport GO:0016197 129 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.036
negative regulation of multicellular organismal process GO:0051241 317 0.036
atp catabolic process GO:0006200 157 0.035
positive regulation of immune system process GO:0002684 283 0.035
negative regulation of cell differentiation GO:0045596 171 0.035
branch elongation of an epithelium GO:0060602 3 0.035
cell development GO:0048468 328 0.035
Worm Fly
positive regulation of neurogenesis GO:0050769 49 0.034
cell projection morphogenesis GO:0048858 129 0.034
notch receptor processing GO:0007220 2 0.033
regulation of nervous system development GO:0051960 88 0.033
secretion by cell GO:0032940 226 0.033
long term synaptic potentiation GO:0060291 1 0.032
positive regulation of cellular amine metabolic process GO:0033240 7 0.032
glycerophospholipid metabolic process GO:0006650 84 0.032
cellular response to interleukin 15 GO:0071350 6 0.032
positive regulation of receptor mediated endocytosis GO:0048260 21 0.031
stress activated protein kinase signaling cascade GO:0031098 94 0.031
negative regulation of phosphorylation GO:0042326 174 0.031
hemopoiesis GO:0030097 180 0.031
kidney development GO:0001822 53 0.031
adult behavior GO:0030534 18 0.031
regulation of cellular component movement GO:0051270 334 0.031
immune effector process GO:0002252 159 0.031
developmental growth GO:0048589 48 0.031
membrane invagination GO:0010324 10 0.031
Worm
regulation of actin filament length GO:0030832 56 0.031
nucleoside monophosphate metabolic process GO:0009123 191 0.031
ameboidal type cell migration GO:0001667 135 0.030
Fly
phagocytosis GO:0006909 42 0.030
Worm
long term memory GO:0007616 2 0.030
cellular ion homeostasis GO:0006873 168 0.030
potassium ion transport GO:0006813 62 0.030
ion homeostasis GO:0050801 230 0.030
bone mineralization GO:0030282 34 0.030
cilium assembly GO:0042384 63 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
circadian behavior GO:0048512 2 0.029
regulation of map kinase activity GO:0043405 108 0.029
cortical cytoskeleton organization GO:0030865 9 0.029
Fly
meiotic chromosome segregation GO:0045132 4 0.028
generation of neurons GO:0048699 152 0.028
lytic vacuole organization GO:0080171 24 0.028
erk1 and erk2 cascade GO:0070371 104 0.028
inositol phosphate dephosphorylation GO:0046855 4 0.028
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.028
response to virus GO:0009615 126 0.028
rho protein signal transduction GO:0007266 26 0.028
negative regulation of endocytosis GO:0045806 19 0.027
protein localization to membrane GO:0072657 160 0.027
morphogenesis of an epithelium GO:0002009 60 0.027
Fly
cellular response to oxygen containing compound GO:1901701 276 0.027
cell part morphogenesis GO:0032990 137 0.027
negative regulation of purine nucleotide metabolic process GO:1900543 28 0.027
regulation of intracellular transport GO:0032386 195 0.027
autophagic vacuole assembly GO:0000045 19 0.027
purine nucleoside monophosphate catabolic process GO:0009128 158 0.027
caveolin mediated endocytosis GO:0072584 4 0.027
positive regulation of aldosterone metabolic process GO:0032346 2 0.027
convergent extension GO:0060026 1 0.027
cell adhesion GO:0007155 325 0.027
regulation of inflammatory response GO:0050727 46 0.026
phosphatidylinositol dephosphorylation GO:0046856 7 0.026
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.026
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.026
mononuclear cell proliferation GO:0032943 71 0.026
proteasomal protein catabolic process GO:0010498 176 0.025
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.025
cognition GO:0050890 43 0.025
Fly
negative regulation of developmental process GO:0051093 247 0.025
negative regulation of cellular catabolic process GO:0031330 83 0.025
membrane biogenesis GO:0044091 13 0.025
regionalization GO:0003002 29 0.025
regulation of receptor internalization GO:0002090 15 0.025
positive regulation of nervous system development GO:0051962 54 0.024
positive regulation of synaptic transmission GO:0050806 4 0.024
photoreceptor cell differentiation GO:0046530 2 0.024
nervous system development GO:0007399 293 0.024
defense response GO:0006952 315 0.024
positive regulation of actin nucleation GO:0051127 6 0.024
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.024
phospholipid dephosphorylation GO:0046839 10 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
regulation of intracellular protein transport GO:0033157 123 0.023
phosphatidylinositol metabolic process GO:0046488 53 0.023
positive regulation of rho gtpase activity GO:0032321 56 0.023
inner ear morphogenesis GO:0042472 4 0.023
negative regulation of nucleotide metabolic process GO:0045980 29 0.023
neural crest cell development GO:0014032 3 0.023
compound eye development GO:0048749 1 0.022
Fly
positive regulation of protein kinase b signaling GO:0051897 42 0.022
nucleic acid transport GO:0050657 39 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
response to hormone GO:0009725 175 0.022
negative regulation of phosphatase activity GO:0010923 61 0.022
regulation of myeloid leukocyte differentiation GO:0002761 39 0.021
regulation of stress fiber assembly GO:0051492 32 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
phosphatidylinositol mediated signaling GO:0048015 55 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.021
rna localization GO:0006403 41 0.021
stem cell development GO:0048864 69 0.021
regulation of cell projection organization GO:0031344 107 0.021
rhythmic behavior GO:0007622 2 0.021
regulation of lymphocyte activation GO:0051249 103 0.020
phagosome maturation GO:0090382 9 0.020
Worm
clathrin coat assembly GO:0048268 6 0.020
transcription factor import into nucleus GO:0042991 40 0.020
regulation of proteolysis GO:0030162 293 0.020
mitotic cytokinesis GO:0000281 19 0.020
Fly
nucleoside monophosphate catabolic process GO:0009125 159 0.020
regeneration GO:0031099 4 0.019
positive regulation of leukocyte chemotaxis GO:0002690 38 0.019
ossification GO:0001503 121 0.019
phagosome acidification GO:0090383 4 0.019
positive regulation of transferase activity GO:0051347 227 0.019
regulation of phosphatase activity GO:0010921 81 0.019
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.019
regulation of protein targeting GO:1903533 91 0.018
response to peptide GO:1901652 65 0.018
mitotic cell cycle phase transition GO:0044772 162 0.018
positive regulation of cell migration GO:0030335 172 0.018
regulation of tolerance induction GO:0002643 4 0.018
cell migration involved in gastrulation GO:0042074 1 0.018
positive regulation of myeloid cell differentiation GO:0045639 39 0.018
regulation of ph GO:0006885 20 0.018
regulation of defense response GO:0031347 154 0.018
autophagy GO:0006914 88 0.018
glomerular epithelial cell development GO:0072310 3 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
early endosome to golgi transport GO:0034498 3 0.017
glial cell differentiation GO:0010001 11 0.017
protein complex disassembly GO:0043241 52 0.017
membrane raft organization GO:0031579 10 0.017
neuron projection development GO:0031175 106 0.017
response to external biotic stimulus GO:0043207 261 0.017
actomyosin structure organization GO:0031032 59 0.017
polyol metabolic process GO:0019751 32 0.017
protein localization to cell surface GO:0034394 28 0.017
leukocyte proliferation GO:0070661 74 0.017
positive regulation of proteolysis GO:0045862 142 0.017
negative regulation of actin filament polymerization GO:0030837 10 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.017
positive regulation of protein localization to cell surface GO:2000010 6 0.017

DNM2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.126
nervous system disease DOID:863 431 0.126
disease of mental health DOID:150 70 0.092
neuropathy DOID:870 52 0.054
kidney disease DOID:557 36 0.049
urinary system disease DOID:18 40 0.049
neurodegenerative disease DOID:1289 102 0.046
disease of metabolism DOID:0014667 295 0.046
developmental disorder of mental health DOID:0060037 29 0.035
neuromuscular disease DOID:440 38 0.033
charcot marie tooth disease DOID:10595 33 0.033
nephritis DOID:10952 6 0.029
glomerulonephritis DOID:2921 6 0.029
glomerulosclerosis DOID:0050851 6 0.029
disease of cellular proliferation DOID:14566 174 0.023
acquired metabolic disease DOID:0060158 58 0.020