Homo sapiens

32 known processes

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

(Aliases: DNMT3A2,M.HsaIIIA)

DNMT3A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone h3 k9 modification GO:0061647 11 0.879
Human
negative regulation of histone h3 k9 methylation GO:0051573 3 0.833
Human
methylation dependent chromatin silencing GO:0006346 3 0.822
Mouse
macromolecule methylation GO:0043414 97 0.795
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.717
Human Mouse
chromatin assembly GO:0031497 61 0.714
histone lysine methylation GO:0034968 50 0.708
Human
genetic imprinting GO:0071514 1 0.629
Mouse
dna methylation on cytosine GO:0032776 3 0.599
histone h3 k4 methylation GO:0051568 27 0.589
Human
dna replication dependent nucleosome organization GO:0034723 32 0.539
dna replication dependent nucleosome assembly GO:0006335 32 0.526
histone modification GO:0016570 251 0.443
Human
protein alkylation GO:0008213 74 0.425
Human
cellular macromolecular complex assembly GO:0034622 324 0.413
response to caffeine GO:0031000 3 0.412
negative regulation of chromatin modification GO:1903309 21 0.406
Human
negative regulation of cellular component organization GO:0051129 235 0.393
Human
negative regulation of chromosome organization GO:2001251 48 0.386
Human
histone methylation GO:0016571 60 0.368
Human
chromatin organization GO:0006325 351 0.367
Human Mouse
cellular amino acid metabolic process GO:0006520 116 0.357
Rat
negative regulation of protein metabolic process GO:0051248 391 0.329
Human
regulation of chromosome organization GO:0033044 103 0.323
Human
cellular response to glucocorticoid stimulus GO:0071385 4 0.309
regulation of cell growth GO:0001558 135 0.292
cellular response to increased oxygen levels GO:0036295 4 0.277
alpha amino acid metabolic process GO:1901605 72 0.275
Rat
chromatin modification GO:0016568 298 0.271
Human Mouse
gene silencing GO:0016458 49 0.260
Mouse
dna hypermethylation GO:0044026 1 0.257
Mouse
negative regulation of epidermal cell differentiation GO:0045605 4 0.247
modification dependent protein catabolic process GO:0019941 209 0.238
multicellular organismal aging GO:0010259 3 0.223
histone monoubiquitination GO:0010390 20 0.215
positive regulation of chromatin modification GO:1903310 30 0.201
Human
regulation of cell cycle arrest GO:0071156 36 0.197
dna replication independent nucleosome organization GO:0034724 27 0.196
dna modification GO:0006304 27 0.194
dna conformation change GO:0071103 113 0.192
response to increased oxygen levels GO:0036296 4 0.184
nucleosome assembly GO:0006334 50 0.181
modification dependent macromolecule catabolic process GO:0043632 212 0.177
positive regulation of organelle organization GO:0010638 195 0.176
Human
nervous system development GO:0007399 293 0.176
Rat
regulation of anatomical structure morphogenesis GO:0022603 286 0.169
positive regulation of cellular component organization GO:0051130 376 0.165
Human
regulation of dna metabolic process GO:0051052 153 0.160
Mouse
metencephalon development GO:0022037 2 0.160
positive regulation of developmental process GO:0051094 314 0.155
response to lipid GO:0033993 206 0.153
Rat
response to cocaine GO:0042220 1 0.152
Rat
negative regulation of histone methylation GO:0031061 6 0.151
Human
positive regulation of chromosome organization GO:2001252 41 0.151
Human
regulation of cell differentiation GO:0045595 393 0.150
nucleosome organization GO:0034728 66 0.149
response to hyperoxia GO:0055093 4 0.148
regulation of chromatin organization GO:1902275 56 0.143
Human
positive regulation of histone h3 k4 methylation GO:0051571 8 0.141
Human
negative regulation of protein modification process GO:0031400 200 0.139
Human
sulfur compound metabolic process GO:0006790 101 0.139
Rat
purine ribonucleoside metabolic process GO:0046128 437 0.137
Rat
response to estradiol GO:0032355 23 0.136
Rat
cellular protein catabolic process GO:0044257 261 0.136
negative regulation of histone modification GO:0031057 19 0.135
Human
cellular response to oxygen containing compound GO:1901701 276 0.134
Mouse Rat
response to activity GO:0014823 0 0.133
positive regulation of cell development GO:0010720 92 0.128
growth GO:0040007 202 0.123
positive regulation of cell growth GO:0030307 48 0.122
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.122
peptidyl lysine methylation GO:0018022 37 0.121
response to radiation GO:0009314 151 0.121
Rat
dna replication independent nucleosome assembly GO:0006336 27 0.118
ubiquitin dependent protein catabolic process GO:0006511 206 0.115
limbic system development GO:0021761 3 0.114
response to abiotic stimulus GO:0009628 336 0.113
Rat
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.112
positive regulation of cell cycle arrest GO:0071158 23 0.110
regulation of cell morphogenesis GO:0022604 153 0.109
chromatin assembly or disassembly GO:0006333 78 0.108
response to estrogen GO:0043627 47 0.106
Rat
regulation of growth GO:0040008 165 0.105
hindbrain development GO:0030902 3 0.104
protein modification by small protein conjugation GO:0032446 342 0.103
protein ubiquitination GO:0016567 314 0.103
covalent chromatin modification GO:0016569 254 0.102
Human Mouse
cellular response to lipid GO:0071396 127 0.101
response to hormone GO:0009725 175 0.100
Rat
regulation of cell development GO:0060284 161 0.099
response to ionizing radiation GO:0010212 65 0.099
Rat
dna methylation or demethylation GO:0044728 19 0.097
retina layer formation GO:0010842 3 0.096
response to decreased oxygen levels GO:0036293 96 0.096
Rat
organelle fission GO:0048285 149 0.094
nuclear division GO:0000280 128 0.094
cellular response to dexamethasone stimulus GO:0071549 1 0.093
cellular response to hyperoxia GO:0071455 4 0.092
response to transforming growth factor beta GO:0071559 94 0.092
cellular component morphogenesis GO:0032989 314 0.091
skeletal system development GO:0001501 79 0.090
regulation of cell cycle process GO:0010564 266 0.089
positive regulation of histone methylation GO:0031062 12 0.087
Human
response to drug GO:0042493 81 0.086
Rat
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.086
regulation of cell cycle GO:0051726 393 0.085
cell growth GO:0016049 160 0.084
cell development GO:0048468 328 0.083
response to acid chemical GO:0001101 66 0.083
Mouse
cellular response to acid chemical GO:0071229 44 0.082
Mouse
neurogenesis GO:0022008 169 0.081
Rat
negative regulation of cellular protein metabolic process GO:0032269 353 0.080
Human
cellular macromolecule catabolic process GO:0044265 380 0.080
regulation of cellular amine metabolic process GO:0033238 11 0.079
negative regulation of cell cycle GO:0045786 193 0.078
protein monoubiquitination GO:0006513 39 0.077
determination of adult lifespan GO:0008340 2 0.077
mitotic cell cycle GO:0000278 326 0.076
Rat
response to purine containing compound GO:0014074 40 0.076
regulation of neuron differentiation GO:0045664 70 0.073
response to oxygen containing compound GO:1901700 369 0.072
Mouse Rat
coenzyme metabolic process GO:0006732 65 0.072
response to organic cyclic compound GO:0014070 204 0.071
Rat
negative regulation of organelle organization GO:0010639 126 0.071
Human
negative regulation of cellular amine metabolic process GO:0033239 3 0.071
regulation of proteolysis GO:0030162 293 0.070
response to steroid hormone GO:0048545 80 0.069
Rat
positive regulation of cell differentiation GO:0045597 211 0.068
regulation of chromatin modification GO:1903308 51 0.066
Human
regulation of neurogenesis GO:0050767 82 0.065
methylation GO:0032259 106 0.065
cell cycle phase transition GO:0044770 173 0.065
response to hypoxia GO:0001666 96 0.065
Rat
protein catabolic process GO:0030163 325 0.065
neuron differentiation GO:0030182 138 0.064
Rat
response to toxic substance GO:0009636 37 0.063
Rat
biological adhesion GO:0022610 331 0.060
cell cycle arrest GO:0007050 71 0.059
response to nitrogen compound GO:1901698 184 0.059
Mouse Rat
response to organonitrogen compound GO:0010243 156 0.057
Mouse Rat
post embryonic development GO:0009791 2 0.057
response to extracellular stimulus GO:0009991 85 0.057
Rat
cellular response to alcohol GO:0097306 29 0.056
Rat
negative regulation of protein processing GO:0010955 142 0.053
embryonic forelimb morphogenesis GO:0035115 4 0.053
cellular response to hormone stimulus GO:0032870 125 0.052
protein methylation GO:0006479 74 0.051
Human
response to alcohol GO:0097305 64 0.051
Rat
dosage compensation GO:0007549 3 0.050
regulation of histone methylation GO:0031060 16 0.049
Human
dna packaging GO:0006323 77 0.048
peptidyl lysine dimethylation GO:0018027 3 0.047
protein processing GO:0016485 226 0.047
negative regulation of dna metabolic process GO:0051053 57 0.046
regulation of proteasomal protein catabolic process GO:0061136 87 0.046
female gamete generation GO:0007292 2 0.046
organ formation GO:0048645 3 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.045
cellular response to oxygen levels GO:0071453 55 0.045
Rat
cellular ketone metabolic process GO:0042180 80 0.044
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.044
regulation of histone h3 k27 methylation GO:0061085 4 0.043
negative regulation of developmental process GO:0051093 247 0.043
osteoblast differentiation GO:0001649 92 0.043
cation transport GO:0006812 331 0.043
regulation of dna methylation GO:0044030 2 0.042
Mouse
membrane organization GO:0061024 292 0.042
positive regulation of neurogenesis GO:0050769 49 0.042
muscle cell differentiation GO:0042692 63 0.042
lipid biosynthetic process GO:0008610 177 0.042
cell morphogenesis GO:0000902 296 0.041
positive regulation of cell cycle process GO:0090068 106 0.041
response to amino acid GO:0043200 14 0.041
Mouse
histone h3 k9 methylation GO:0051567 10 0.041
Human
response to ketone GO:1901654 19 0.040
oogenesis GO:0048477 2 0.040
cellular response to organonitrogen compound GO:0071417 124 0.039
Mouse
response to nutrient levels GO:0031667 81 0.039
Rat
cell adhesion GO:0007155 325 0.039
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.039
negative regulation of protein maturation GO:1903318 142 0.039
system process GO:0003008 349 0.038
positive regulation of neuron differentiation GO:0045666 40 0.038
regulation of cell cycle phase transition GO:1901987 126 0.038
cell projection organization GO:0030030 252 0.037
single organism membrane organization GO:0044802 268 0.037
nucleotide catabolic process GO:0009166 408 0.037
regulation of nervous system development GO:0051960 88 0.037
cerebellum development GO:0021549 2 0.037
response to nutrient GO:0007584 20 0.037
Rat
reproductive process GO:0022414 106 0.036
Mouse
response to dexamethasone GO:0071548 1 0.036
ossification GO:0001503 121 0.035
cellular response to corticosteroid stimulus GO:0071384 5 0.035
inorganic ion transmembrane transport GO:0098660 231 0.035
locomotory behavior GO:0007626 1 0.035
anatomical structure formation involved in morphogenesis GO:0048646 284 0.035
regulation of cellular ketone metabolic process GO:0010565 50 0.034
circulatory system development GO:0072359 262 0.034
negative regulation of epidermis development GO:0045683 5 0.034
ras protein signal transduction GO:0007265 73 0.034
positive regulation of cellular catabolic process GO:0031331 284 0.033
metaphase anaphase transition of cell cycle GO:0044784 21 0.033
intracellular receptor signaling pathway GO:0030522 104 0.033
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
lipid metabolic process GO:0006629 381 0.032
gtp catabolic process GO:0006184 237 0.031
nucleoside catabolic process GO:0009164 408 0.031
glycosyl compound catabolic process GO:1901658 413 0.031
mitotic sister chromatid separation GO:0051306 18 0.031
protein autophosphorylation GO:0046777 123 0.031
regulation of protein maturation GO:1903317 150 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.030
negative regulation of mitotic cell cycle GO:0045930 102 0.030
regulation of gene expression by genetic imprinting GO:0006349 1 0.030
Mouse
carbohydrate metabolic process GO:0005975 207 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
spinal cord development GO:0021510 4 0.030
memory GO:0007613 3 0.030
single organism carbohydrate metabolic process GO:0044723 193 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
regulation of mitotic cell cycle phase transition GO:1901990 118 0.029
cellular amine metabolic process GO:0044106 41 0.029
purine nucleoside catabolic process GO:0006152 398 0.029
positive regulation of nucleotide catabolic process GO:0030813 185 0.029
mesenchymal cell development GO:0014031 50 0.029
amine metabolic process GO:0009308 44 0.029
inorganic cation transmembrane transport GO:0098662 194 0.029
digestive system development GO:0055123 75 0.029
cytoplasmic transport GO:0016482 379 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.028
histone ubiquitination GO:0016574 31 0.028
blastoderm segmentation GO:0007350 2 0.028
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
positive regulation of hydrolase activity GO:0051345 331 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
regulation of ion transport GO:0043269 189 0.028
regulation of gene silencing GO:0060968 24 0.028
axis elongation GO:0003401 4 0.027
pituitary gland development GO:0021983 2 0.027
hippocampus development GO:0021766 1 0.027
enzyme linked receptor protein signaling pathway GO:0007167 303 0.027
regulation of protein catabolic process GO:0042176 155 0.027
embryonic digestive tract morphogenesis GO:0048557 2 0.027
response to testosterone GO:0033574 1 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
cellular lipid metabolic process GO:0044255 303 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.026
proteasomal protein catabolic process GO:0010498 176 0.026
positive regulation of histone modification GO:0031058 29 0.026
Human
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.026
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.025
positive regulation of catabolic process GO:0009896 310 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
epithelial cell differentiation GO:0030855 141 0.025
chemotaxis GO:0006935 157 0.025
positive regulation of protein kinase activity GO:0045860 190 0.025
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.025
cofactor metabolic process GO:0051186 87 0.025
lens development in camera type eye GO:0002088 2 0.024
regulation of mitosis GO:0007088 63 0.024
tissue morphogenesis GO:0048729 96 0.024
positive regulation of kinase activity GO:0033674 204 0.024
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.024
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.024
protein maturation GO:0051604 233 0.024
metal ion transport GO:0030001 272 0.024
inner ear morphogenesis GO:0042472 4 0.024
myosin filament assembly GO:0031034 2 0.024
regulation of purine nucleotide catabolic process GO:0033121 205 0.024
actin filament based process GO:0030029 224 0.024
signal transduction by phosphorylation GO:0023014 297 0.023
negative regulation of cell differentiation GO:0045596 171 0.023
regulation of glial cell proliferation GO:0060251 4 0.023
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.023
protein dna complex subunit organization GO:0071824 80 0.023
regulation of cell shape GO:0008360 48 0.023
mitotic cell cycle checkpoint GO:0007093 68 0.023
positive regulation of ion transport GO:0043270 87 0.023
stem cell division GO:0017145 2 0.023
generation of neurons GO:0048699 152 0.023
Rat
mitotic nuclear division GO:0007067 119 0.023
ion homeostasis GO:0050801 230 0.023
forelimb morphogenesis GO:0035136 4 0.022
dephosphorylation GO:0016311 209 0.022
positive regulation of gliogenesis GO:0014015 4 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
motor neuron axon guidance GO:0008045 2 0.022
demethylation GO:0070988 37 0.022
actin mediated cell contraction GO:0070252 12 0.022
response to ethanol GO:0045471 11 0.022
Rat
guanosine containing compound metabolic process GO:1901068 244 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 4 0.021
establishment of planar polarity GO:0001736 3 0.021
rna processing GO:0006396 255 0.021
reactive oxygen species biosynthetic process GO:1903409 4 0.021
nerve development GO:0021675 4 0.021
protein localization to organelle GO:0033365 280 0.021
stem cell differentiation GO:0048863 93 0.021
organophosphate catabolic process GO:0046434 430 0.021
positive regulation of transferase activity GO:0051347 227 0.021
chemical homeostasis GO:0048878 306 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
response to external biotic stimulus GO:0043207 261 0.021
ameboidal type cell migration GO:0001667 135 0.021
cellular response to endogenous stimulus GO:0071495 336 0.021
Mouse
positive regulation of apoptotic process GO:0043065 246 0.020
cardiac muscle cell contraction GO:0086003 4 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
reactive nitrogen species metabolic process GO:2001057 3 0.020
regulation of wnt signaling pathway GO:0030111 123 0.020
neuron development GO:0048666 113 0.020
regulation of cellular component movement GO:0051270 334 0.020
regulation of neuron projection development GO:0010975 57 0.020
tissue regeneration GO:0042246 3 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
peripheral nervous system development GO:0007422 2 0.020
regulation of cell division GO:0051302 116 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
neurological system process GO:0050877 163 0.019
cell division GO:0051301 168 0.019
maintenance of dna methylation GO:0010216 3 0.019
transmembrane transport GO:0055085 399 0.019
response to growth factor GO:0070848 205 0.019
segmentation GO:0035282 4 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
positive regulation of nervous system development GO:0051962 54 0.019
protein dephosphorylation GO:0006470 81 0.019
muscle structure development GO:0061061 98 0.019
single organism reproductive process GO:0044702 98 0.019
Mouse
cellular response to metal ion GO:0071248 43 0.019
regulation of cell projection organization GO:0031344 107 0.019
response to biotic stimulus GO:0009607 276 0.019
intracellular protein transport GO:0006886 270 0.019
morphogenesis of a polarized epithelium GO:0001738 3 0.018
nuclear transport GO:0051169 179 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
regulation of protein localization GO:0032880 296 0.018
regulation of sister chromatid segregation GO:0033045 27 0.018
monovalent inorganic cation transport GO:0015672 128 0.018
purine containing compound catabolic process GO:0072523 411 0.018
muscle system process GO:0003012 81 0.018
negative regulation of muscle cell differentiation GO:0051148 17 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.018
embryo development GO:0009790 123 0.018
Mouse
neuromuscular junction development GO:0007528 3 0.018
actin cytoskeleton organization GO:0030036 207 0.018
negative regulation of multi organism process GO:0043901 92 0.018
regulation of homeostatic process GO:0032844 121 0.018
regeneration GO:0031099 4 0.017
regulation of ion transmembrane transport GO:0034765 132 0.017
spermatid differentiation GO:0048515 4 0.017
male meiosis GO:0007140 1 0.017
regulation of cell migration GO:0030334 289 0.017
central nervous system development GO:0007417 123 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
cellular potassium ion transport GO:0071804 60 0.017
mapk cascade GO:0000165 288 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
histone deacetylation GO:0016575 32 0.017
organ morphogenesis GO:0009887 147 0.017
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
regulation of mapk cascade GO:0043408 262 0.016
negative regulation of glial cell proliferation GO:0060253 2 0.016
rostrocaudal neural tube patterning GO:0021903 1 0.016
potassium ion transport GO:0006813 62 0.016
cellular protein complex assembly GO:0043623 188 0.016
fatty acid metabolic process GO:0006631 115 0.016
regulation of response to external stimulus GO:0032101 222 0.016
stem cell development GO:0048864 69 0.016
negative regulation of wnt signaling pathway GO:0030178 69 0.016
somatic stem cell maintenance GO:0035019 4 0.016
cellular response to ketone GO:1901655 9 0.016
protein acylation GO:0043543 138 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
protein dna complex assembly GO:0065004 64 0.016
negative regulation of cell cycle process GO:0010948 121 0.016
response to oxygen levels GO:0070482 100 0.015
Rat
ion transmembrane transport GO:0034220 338 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
mitochondrion organization GO:0007005 156 0.015
cell type specific apoptotic process GO:0097285 125 0.015
Rat
negative regulation of cell division GO:0051782 31 0.015
response to other organism GO:0051707 261 0.015
sister chromatid segregation GO:0000819 54 0.015
macromolecule deacylation GO:0098732 41 0.015
response to fungus GO:0009620 4 0.015
establishment of tissue polarity GO:0007164 3 0.015
small molecule catabolic process GO:0044282 92 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
response to vitamin GO:0033273 13 0.015
Rat
organic acid biosynthetic process GO:0016053 97 0.015
sodium ion export from cell GO:0036376 6 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
regulation of metal ion transport GO:0010959 120 0.015
regulation of nuclear division GO:0051783 65 0.015
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.015
epithelial to mesenchymal transition GO:0001837 48 0.015
brain development GO:0007420 97 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
neuron projection development GO:0031175 106 0.015
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.015
epithelium development GO:0060429 227 0.015
negative regulation of cellular catabolic process GO:0031330 83 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.015
positive regulation of growth GO:0045927 58 0.015
defense response to fungus GO:0050832 4 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
spermatid development GO:0007286 4 0.015
single organismal cell cell adhesion GO:0016337 148 0.015
regulation of histone h3 k9 methylation GO:0051570 6 0.014
Human
regulation of axon guidance GO:1902667 3 0.014
secretion by cell GO:0032940 226 0.014
peptidyl lysine acetylation GO:0018394 101 0.014
sequestering of calcium ion GO:0051208 17 0.014
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.014
regulation of ossification GO:0030278 58 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
regulation of stem cell differentiation GO:2000736 56 0.014
regulation of cellular protein catabolic process GO:1903362 96 0.014
positive regulation of dendrite morphogenesis GO:0050775 3 0.014
anion transport GO:0006820 161 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
cellular response to organic cyclic compound GO:0071407 127 0.014
protein targeting GO:0006605 187 0.014
mitotic sister chromatid segregation GO:0000070 53 0.014
tissue migration GO:0090130 119 0.014
regulation of map kinase activity GO:0043405 108 0.014
mitotic spindle assembly checkpoint GO:0007094 14 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
taxis GO:0042330 157 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
striated muscle myosin thick filament assembly GO:0071688 2 0.014
positive regulation of cell adhesion GO:0045785 84 0.014
regulation of cell adhesion GO:0030155 166 0.014
positive regulation of cell projection organization GO:0031346 64 0.014
regulation of mitotic sister chromatid separation GO:0010965 27 0.014
cell part morphogenesis GO:0032990 137 0.014
positive regulation of vasoconstriction GO:0045907 3 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
digestive tract development GO:0048565 75 0.014
positive regulation of gtpase activity GO:0043547 166 0.014
negative regulation of cell death GO:0060548 345 0.014
chromatin silencing GO:0006342 12 0.014
Mouse
negative regulation of synaptic transmission GO:0050805 2 0.013
negative regulation of retinoic acid receptor signaling pathway GO:0048387 4 0.013
cell cell junction organization GO:0045216 69 0.013
epithelium migration GO:0090132 119 0.013
negative regulation of chromosome segregation GO:0051985 18 0.013
positive regulation of map kinase activity GO:0043406 80 0.013
potassium ion transmembrane transport GO:0071805 60 0.013
negative regulation of proteolysis GO:0045861 132 0.013
regulation of locomotion GO:0040012 329 0.013
meiotic cell cycle GO:0051321 13 0.013
actin filament based movement GO:0030048 17 0.013
epithelial cell proliferation GO:0050673 128 0.013
protein localization to membrane GO:0072657 160 0.013
endodermal cell fate commitment GO:0001711 4 0.013
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.013
regulation of gtpase activity GO:0043087 180 0.013
embryonic viscerocranium morphogenesis GO:0048703 1 0.013
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.013
blastocyst development GO:0001824 3 0.013
wnt signaling pathway GO:0016055 156 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
calcium ion transmembrane transport GO:0070588 76 0.013
multicellular organismal signaling GO:0035637 34 0.013
glial cell migration GO:0008347 4 0.013
metal ion homeostasis GO:0055065 169 0.013
action potential GO:0001508 34 0.013
response to axon injury GO:0048678 1 0.013
mitotic cell cycle process GO:1903047 286 0.013
regulation of growth rate GO:0040009 1 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013

DNMT3A disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.206
neuropathy DOID:870 52 0.206
peripheral neuropathy DOID:0060053 12 0.089
musculoskeletal system disease DOID:17 223 0.024
disease of metabolism DOID:0014667 295 0.018
physical disorder DOID:0080015 41 0.016
connective tissue disease DOID:65 109 0.016
sensory system disease DOID:0050155 203 0.013