Homo sapiens

236 known processes

DRD2

dopamine receptor D2

(Aliases: D2R,D2DR)

DRD2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 2 1.000
glycine import GO:0036233 1 1.000
catecholamine transport GO:0051937 6 1.000
Mouse Rat
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 1.000
camp biosynthetic process GO:0006171 47 1.000
regulation of excretion GO:0044062 1 1.000
Mouse
catecholamine secretion GO:0050432 1 1.000
Mouse Rat
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.999
synaptic transmission glycinergic GO:0060012 1 0.999
purinergic receptor signaling pathway GO:0035587 8 0.999
positive regulation of camp biosynthetic process GO:0030819 35 0.998
regulation of amine transport GO:0051952 5 0.997
Mouse Rat
camp metabolic process GO:0046058 61 0.996
sodium ion homeostasis GO:0055078 14 0.996
Mouse
g protein coupled receptor signaling pathway GO:0007186 207 0.996
positive regulation of adenylate cyclase activity GO:0045762 12 0.996
synaptic transmission cholinergic GO:0007271 2 0.996
norepinephrine transport GO:0015874 1 0.995
regulation of camp biosynthetic process GO:0030817 45 0.995
organic hydroxy compound transport GO:0015850 63 0.994
Mouse Rat
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.994
regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010578 5 0.994
regulation of catecholamine secretion GO:0050433 1 0.994
Mouse Rat
cyclic nucleotide metabolic process GO:0009187 82 0.993
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 5 0.991
amino acid transport GO:0006865 28 0.989
anion transport GO:0006820 161 0.984
serotonin uptake GO:0051610 2 0.981
circadian behavior GO:0048512 2 0.980
Rat
glycine transport GO:0015816 3 0.977
response to organonitrogen compound GO:0010243 156 0.976
monoamine transport GO:0015844 10 0.976
Mouse Rat
neurotransmitter secretion GO:0007269 4 0.973
regulation of camp metabolic process GO:0030814 52 0.972
cyclic nucleotide biosynthetic process GO:0009190 61 0.970
cation transport GO:0006812 331 0.968
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.968
rhythmic behavior GO:0007622 2 0.966
Rat
nucleoside phosphate biosynthetic process GO:1901293 109 0.965
locomotory behavior GO:0007626 1 0.963
Mouse Rat
negative regulation of alpha beta t cell activation GO:0046636 3 0.953
metal ion transport GO:0030001 272 0.951
transmembrane transport GO:0055085 399 0.950
regulation of neurotransmitter secretion GO:0046928 3 0.946
cell cell signaling GO:0007267 155 0.943
positive regulation of organic acid transport GO:0032892 3 0.939
positive regulation of cyclase activity GO:0031281 13 0.931
positive regulation of synaptic transmission GO:0050806 4 0.930
Mouse Rat
calcium ion transport GO:0006816 147 0.929
circadian sleep wake cycle GO:0042745 2 0.925
Rat
ion transmembrane transport GO:0034220 338 0.923
cation homeostasis GO:0055080 189 0.915
nucleotide biosynthetic process GO:0009165 109 0.908
purine ribonucleotide biosynthetic process GO:0009152 79 0.907
synaptic transmission GO:0007268 61 0.901
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.900
amine transport GO:0015837 7 0.896
Mouse Rat
ion homeostasis GO:0050801 230 0.891
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.889
regulation of cyclase activity GO:0031279 19 0.889
response to purine containing compound GO:0014074 40 0.888
cation transmembrane transport GO:0098655 238 0.887
circadian sleep wake cycle process GO:0022410 2 0.885
Rat
positive regulation of ion transport GO:0043270 87 0.885
Human Mouse
acid secretion GO:0046717 12 0.883
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.867
inorganic ion transmembrane transport GO:0098660 231 0.857
proline transport GO:0015824 4 0.849
response to nitrogen compound GO:1901698 184 0.847
organic anion transport GO:0015711 103 0.847
renal system process GO:0003014 25 0.845
Mouse
positive regulation of amine transport GO:0051954 2 0.845
Mouse
regulation of secretion by cell GO:1903530 177 0.844
regulation of lyase activity GO:0051339 23 0.843
neuron neuron synaptic transmission GO:0007270 6 0.841
Mouse Rat
vasodilation GO:0042311 4 0.839
membrane hyperpolarization GO:0060081 1 0.839
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.835
adenosine receptor signaling pathway GO:0001973 4 0.832
neurotransmitter transport GO:0006836 10 0.819
Mouse
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.817
positive regulation of camp metabolic process GO:0030816 41 0.809
signal release GO:0023061 70 0.804
Mouse Rat
chemical homeostasis GO:0048878 306 0.791
divalent inorganic cation transport GO:0072511 158 0.784
organophosphate biosynthetic process GO:0090407 163 0.779
regulation of nucleotide biosynthetic process GO:0030808 50 0.775
response to caffeine GO:0031000 3 0.775
system process GO:0003008 349 0.775
Human Mouse Rat
regulation of blood vessel size GO:0050880 18 0.769
astrocyte differentiation GO:0048708 4 0.756
cellular divalent inorganic cation homeostasis GO:0072503 128 0.752
positive regulation of neurotransmitter transport GO:0051590 1 0.749
Mouse
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.747
g protein coupled purinergic receptor signaling pathway GO:0035588 5 0.741
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.738
Rat
amino acid transmembrane transport GO:0003333 20 0.719
glial cell development GO:0021782 7 0.707
regulation of purine nucleotide metabolic process GO:1900542 264 0.701
regulation of system process GO:0044057 101 0.698
Mouse
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.679
circadian sleep wake cycle sleep GO:0050802 2 0.668
Rat
excretion GO:0007588 9 0.651
Mouse
response to alkaloid GO:0043279 20 0.617
Human Mouse Rat
positive regulation of nucleotide metabolic process GO:0045981 230 0.610
acetylcholine secretion GO:0061526 1 0.609
purine containing compound biosynthetic process GO:0072522 88 0.599
synaptic transmission involved in micturition GO:0060084 2 0.595
heart contraction GO:0060047 62 0.577
Mouse
generation of neurons GO:0048699 152 0.573
Mouse
secretion by cell GO:0032940 226 0.560
metal ion homeostasis GO:0055065 169 0.559
central nervous system development GO:0007417 123 0.545
Mouse Rat
response to drug GO:0042493 81 0.545
Mouse Rat
l amino acid import GO:0043092 4 0.541
micturition GO:0060073 3 0.532
regulation of ion homeostasis GO:2000021 73 0.526
Mouse Rat
positive regulation of secretion by cell GO:1903532 108 0.524
Mouse
cellular homeostasis GO:0019725 196 0.523
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.522
response to organic cyclic compound GO:0014070 204 0.521
positive regulation of protein kinase activity GO:0045860 190 0.512
Human Rat
secretion GO:0046903 254 0.511
positive regulation of lyase activity GO:0051349 16 0.494
serotonin transport GO:0006837 3 0.486
neurological system process GO:0050877 163 0.482
Human Mouse Rat
regulation of neurotransmitter transport GO:0051588 7 0.471
Mouse
regulation of hormone levels GO:0010817 125 0.463
Mouse Rat
regulation of mitochondrial membrane potential GO:0051881 23 0.453
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.453
positive regulation of secretion GO:0051047 116 0.447
Mouse
regulation of locomotion GO:0040012 329 0.441
Mouse Rat
regulation of homeostatic process GO:0032844 121 0.426
Mouse Rat
nitrogen compound transport GO:0071705 191 0.423
Mouse Rat
regulation of body fluid levels GO:0050878 99 0.413
Mouse
blood circulation GO:0008015 113 0.406
Mouse
cellular chemical homeostasis GO:0055082 180 0.404
regulation of apoptotic signaling pathway GO:2001233 175 0.387
cyclic purine nucleotide metabolic process GO:0052652 60 0.377
cellular metal ion homeostasis GO:0006875 146 0.374
vascular process in circulatory system GO:0003018 29 0.366
regulation of membrane potential GO:0042391 95 0.357
regulation of peptidase activity GO:0052547 180 0.356
heart process GO:0003015 62 0.349
Mouse
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.340
anion transmembrane transport GO:0098656 76 0.337
regulation of establishment of protein localization GO:0070201 242 0.335
nervous system development GO:0007399 293 0.333
Mouse Rat
ribose phosphate biosynthetic process GO:0046390 82 0.333
calcium ion homeostasis GO:0055074 122 0.331
regulation of calcium ion transport GO:0051924 79 0.329
regulation of nucleotide metabolic process GO:0006140 269 0.325
cell development GO:0048468 328 0.322
Mouse
neurogenesis GO:0022008 169 0.321
Mouse
tissue homeostasis GO:0001894 63 0.304
positive regulation of cell death GO:0010942 263 0.303
carnitine transmembrane transport GO:1902603 3 0.290
regulation of metal ion transport GO:0010959 120 0.283
regulation of protein secretion GO:0050708 86 0.277
cytosolic calcium ion homeostasis GO:0051480 89 0.276
negative regulation of protein maturation GO:1903318 142 0.272
inorganic cation transmembrane transport GO:0098662 194 0.261
response to nicotine GO:0035094 12 0.260
Rat
peptide secretion GO:0002790 51 0.259
Mouse Rat
ribonucleotide biosynthetic process GO:0009260 81 0.256
carbohydrate derivative biosynthetic process GO:1901137 207 0.255
neuron projection development GO:0031175 106 0.252
Mouse
thalamus development GO:0021794 2 0.240
regulation of postsynaptic membrane potential GO:0060078 1 0.238
regulation of secretion GO:0051046 194 0.238
regulation of protein transport GO:0051223 213 0.234
amino acid import GO:0043090 4 0.234
cellular ion homeostasis GO:0006873 168 0.233
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.227
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.225
regulation of ion transport GO:0043269 189 0.223
regulation of circadian rhythm GO:0042752 11 0.222
Rat
cell projection organization GO:0030030 252 0.222
Mouse
response to camp GO:0051591 25 0.220
organonitrogen compound biosynthetic process GO:1901566 200 0.216
negative regulation of secretion by cell GO:1903531 52 0.212
negative regulation of catalytic activity GO:0043086 335 0.203
lymphocyte activation GO:0046649 133 0.202
carboxylic acid transport GO:0046942 63 0.197
astrocyte development GO:0014002 1 0.196
regulation of synaptic plasticity GO:0048167 3 0.196
Mouse Rat
response to inorganic substance GO:0010035 127 0.196
Rat
negative regulation of response to wounding GO:1903035 47 0.195
regulation of behavior GO:0050795 82 0.195
Rat
positive regulation of transport GO:0051050 336 0.195
Human Mouse Rat
sensory perception GO:0007600 103 0.185
Mouse
peptide transport GO:0015833 74 0.185
Mouse Rat
regulation of defense response GO:0031347 154 0.184
cellular component morphogenesis GO:0032989 314 0.182
Mouse
behavior GO:0007610 112 0.178
Human Mouse Rat
cellular cation homeostasis GO:0030003 163 0.176
hormone secretion GO:0046879 65 0.174
Mouse Rat
positive regulation of programmed cell death GO:0043068 249 0.172
apoptotic signaling pathway GO:0097190 268 0.172
neuromuscular process GO:0050905 15 0.166
Human Mouse
protein secretion GO:0009306 98 0.165
negative regulation of cell proliferation GO:0008285 228 0.164
Mouse
cell type specific apoptotic process GO:0097285 125 0.162
regulation of transmembrane transporter activity GO:0022898 74 0.160
regulation of response to wounding GO:1903034 101 0.157
regulation of anatomical structure size GO:0090066 101 0.153
regulation of leukocyte activation GO:0002694 115 0.153
negative regulation of vascular permeability GO:0043116 7 0.151
anatomical structure homeostasis GO:0060249 100 0.149
negative regulation of protein processing GO:0010955 142 0.149
regulation of organic acid transport GO:0032890 8 0.147
defense response GO:0006952 315 0.146
neuron fate commitment GO:0048663 2 0.145
regulation of transporter activity GO:0032409 82 0.142
multicellular organismal homeostasis GO:0048871 67 0.141
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.139
negative regulation of synaptic transmission GO:0050805 2 0.139
Mouse
regulation of lymphocyte activation GO:0051249 103 0.133
neuropeptide signaling pathway GO:0007218 19 0.133
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.132
Human
cell differentiation in spinal cord GO:0021515 1 0.130
positive regulation of cellular amine metabolic process GO:0033240 7 0.128
regulation of protein kinase activity GO:0045859 289 0.128
Human Rat
positive regulation of intestinal epithelial structure maintenance GO:0060731 1 0.128
negative regulation of peptidase activity GO:0010466 91 0.127
positive regulation of behavior GO:0048520 60 0.126
negative regulation of cellular protein metabolic process GO:0032269 353 0.125
negative regulation of leukocyte activation GO:0002695 26 0.125
purine nucleotide biosynthetic process GO:0006164 84 0.124
somatostatin receptor signaling pathway GO:0038169 1 0.122
regulation of transmembrane transport GO:0034762 139 0.122
negative regulation of secretion GO:0051048 58 0.118
response to disaccharide GO:0034285 1 0.117
rhythmic process GO:0048511 31 0.115
Mouse Rat
response to alcohol GO:0097305 64 0.115
Mouse Rat
growth GO:0040007 202 0.112
Mouse
circadian rhythm GO:0007623 21 0.111
Mouse Rat
cell part morphogenesis GO:0032990 137 0.111
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.110
regulation of transferase activity GO:0051338 355 0.109
Human Rat
hormone transport GO:0009914 68 0.108
Mouse Rat
potassium ion transport GO:0006813 62 0.107
Mouse Rat
regulation of synaptic transmission GO:0050804 11 0.107
Mouse Rat
negative regulation of cell differentiation GO:0045596 171 0.107
negative regulation of cell death GO:0060548 345 0.106
divalent inorganic cation homeostasis GO:0072507 136 0.106
response to ethanol GO:0045471 11 0.105
Mouse Rat
regulation of protein maturation GO:1903317 150 0.104
positive regulation of apoptotic process GO:0043065 246 0.104
cellular ketone metabolic process GO:0042180 80 0.103
monovalent inorganic cation transport GO:0015672 128 0.102
Human Mouse Rat
regulation of peptide secretion GO:0002791 42 0.102
Mouse Rat
leukocyte activation GO:0045321 164 0.101
positive regulation of transferase activity GO:0051347 227 0.100
Human Rat
amide transport GO:0042886 76 0.099
Mouse Rat
positive regulation of protein secretion GO:0050714 60 0.098
negative regulation of endopeptidase activity GO:0010951 84 0.098
negative regulation of phosphorus metabolic process GO:0010563 267 0.097
negative regulation of immune system process GO:0002683 136 0.097
neuron differentiation GO:0030182 138 0.096
Mouse
spinal cord development GO:0021510 4 0.093
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 1 0.092
regulation of proteolysis GO:0030162 293 0.091
purine nucleoside triphosphate catabolic process GO:0009146 392 0.091
activation of protein kinase activity GO:0032147 90 0.091
Human Rat
acetylcholine transport GO:0015870 1 0.090
circulatory system process GO:0003013 113 0.090
Mouse
regulation of cell activation GO:0050865 125 0.089
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.087
memory GO:0007613 3 0.086
Rat
response to organophosphorus GO:0046683 41 0.086
response to oxygen containing compound GO:1901700 369 0.086
Human Mouse Rat
positive regulation of circadian sleep wake cycle sleep GO:0045938 1 0.086
organic acid transport GO:0015849 65 0.086
cell activation GO:0001775 213 0.086
positive regulation of apoptotic signaling pathway GO:2001235 70 0.086
negative regulation of protein modification process GO:0031400 200 0.085
regulation of cysteine type endopeptidase activity GO:2000116 127 0.083
regulation of ion transmembrane transport GO:0034765 132 0.083
negative regulation of kinase activity GO:0033673 106 0.082
negative regulation of apoptotic process GO:0043066 316 0.082
nucleoside catabolic process GO:0009164 408 0.080
negative regulation of cell activation GO:0050866 33 0.079
inflammatory response GO:0006954 79 0.078
regulation of peptide transport GO:0090087 62 0.077
Mouse Rat
one carbon compound transport GO:0019755 4 0.077
cellular calcium ion homeostasis GO:0006874 117 0.076
signal transduction by phosphorylation GO:0023014 297 0.074
Human Rat
cell projection morphogenesis GO:0048858 129 0.074
Mouse
muscle contraction GO:0006936 73 0.072
Mouse
negative regulation of developmental process GO:0051093 247 0.071
ribonucleoside monophosphate metabolic process GO:0009161 187 0.071
cell morphogenesis GO:0000902 296 0.071
Mouse
positive regulation of digestive system process GO:0060456 2 0.070
t cell activation GO:0042110 99 0.069
protein processing GO:0016485 226 0.069
regulation of protein localization GO:0032880 296 0.069
negative regulation of programmed cell death GO:0043069 321 0.069
neuromuscular junction development GO:0007528 3 0.069
somatostatin signaling pathway GO:0038170 1 0.069
positive regulation of blood pressure GO:0045777 3 0.069
regulation of hormone secretion GO:0046883 57 0.067
Mouse Rat
homeostasis of number of cells GO:0048872 40 0.066
cellular potassium ion transport GO:0071804 60 0.065
regulation of sensory perception GO:0051931 3 0.065
protein maturation GO:0051604 233 0.064
visual behavior GO:0007632 2 0.064
Mouse
dicarboxylic acid transport GO:0006835 13 0.064
membrane depolarization GO:0051899 26 0.064
associative learning GO:0008306 1 0.063
Mouse
negative regulation of wnt protein secretion GO:0061358 1 0.063
negative regulation of amine transport GO:0051953 1 0.063
Rat
negative regulation of voltage gated calcium channel activity GO:1901386 4 0.063
forebrain development GO:0030900 26 0.062
Mouse Rat
response to transition metal nanoparticle GO:1990267 29 0.062
Rat
cytokine production GO:0001816 247 0.062
brain development GO:0007420 97 0.061
Mouse Rat
activation of mapk activity GO:0000187 45 0.061
Human
membrane organization GO:0061024 292 0.060
regulation of cellular amine metabolic process GO:0033238 11 0.060
glial cell differentiation GO:0010001 11 0.059
serotonin receptor signaling pathway GO:0007210 11 0.059
negative regulation of protein phosphorylation GO:0001933 140 0.059
positive regulation of glucocorticoid secretion GO:2000851 4 0.059
positive regulation of phosphorylation GO:0042327 394 0.058
Human Rat
gas transport GO:0015669 3 0.057
nucleoside triphosphate metabolic process GO:0009141 422 0.057
l amino acid transport GO:0015807 14 0.056
regulation of inflammatory response GO:0050727 46 0.055
regulation of vesicle mediated transport GO:0060627 130 0.055
Rat
purine nucleoside triphosphate metabolic process GO:0009144 412 0.055
negative regulation of defense response GO:0031348 47 0.055
regulation of cellular ketone metabolic process GO:0010565 50 0.054
response to abiotic stimulus GO:0009628 336 0.054
Mouse Rat
negative regulation of protein kinase activity GO:0006469 98 0.054
regulation of growth GO:0040008 165 0.053
Mouse
regulation of alpha beta t cell activation GO:0046634 13 0.053
cellular amine metabolic process GO:0044106 41 0.053
negative regulation of protein metabolic process GO:0051248 391 0.053
neurotransmitter uptake GO:0001504 5 0.053
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.052
negative regulation of proteolysis GO:0045861 132 0.052
negative regulation of transferase activity GO:0051348 124 0.052
regulation of t cell activation GO:0050863 77 0.052
detection of stimulus GO:0051606 85 0.051
regulation of cell development GO:0060284 161 0.051
Mouse
cannabinoid signaling pathway GO:0038171 2 0.050
inner ear morphogenesis GO:0042472 4 0.050
cell projection assembly GO:0030031 126 0.050
nicotinate transport GO:2001142 1 0.049
regulation of muscle system process GO:0090257 53 0.049
calcium ion transmembrane transport GO:0070588 76 0.049
regulation of neuron apoptotic process GO:0043523 35 0.048
single organism carbohydrate metabolic process GO:0044723 193 0.048
single organism behavior GO:0044708 28 0.047
Human Mouse Rat
neuron projection morphogenesis GO:0048812 50 0.047
Mouse
glycosyl compound catabolic process GO:1901658 413 0.047
cyclic nucleotide mediated signaling GO:0019935 26 0.047
gliogenesis GO:0042063 21 0.047
sensory perception of pain GO:0019233 4 0.046
sodium ion export from cell GO:0036376 6 0.046
response to iron ion GO:0010039 6 0.045
Rat
positive regulation of protein transport GO:0051222 135 0.045
adult locomotory behavior GO:0008344 1 0.045
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.045
regulation of endopeptidase activity GO:0052548 170 0.044
positive regulation of large conductance calcium activated potassium channel activity GO:1902608 2 0.044
short chain fatty acid import GO:0015913 1 0.044
copulation GO:0007620 1 0.043
positive regulation of developmental process GO:0051094 314 0.043
Mouse
neuron apoptotic process GO:0051402 39 0.043
ribonucleoside triphosphate metabolic process GO:0009199 412 0.042
potassium ion import GO:0010107 9 0.042
peptidyl tyrosine modification GO:0018212 170 0.042
hindbrain development GO:0030902 3 0.042
organ morphogenesis GO:0009887 147 0.042
regulation of cell migration GO:0030334 289 0.042
Mouse
negative regulation of transport GO:0051051 176 0.042
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.042
Human
ribonucleotide catabolic process GO:0009261 405 0.042
regulation of adenylate cyclase activity GO:0045761 17 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.041
negative regulation of phosphorylation GO:0042326 174 0.041
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.041
determination of adult lifespan GO:0008340 2 0.041
mapk cascade GO:0000165 288 0.041
Human Rat
regulation of protein serine threonine kinase activity GO:0071900 179 0.040
Human
negative regulation of response to external stimulus GO:0032102 83 0.040
Human Mouse
positive regulation of cellular component organization GO:0051130 376 0.040
Rat
ribonucleoside catabolic process GO:0042454 406 0.039
single organism membrane organization GO:0044802 268 0.039
monovalent inorganic cation homeostasis GO:0055067 37 0.039
Mouse
response to other organism GO:0051707 261 0.039
positive regulation of kinase activity GO:0033674 204 0.038
Human Rat
ribonucleoside monophosphate catabolic process GO:0009158 158 0.038
regulation of protein complex assembly GO:0043254 147 0.038
tube development GO:0035295 125 0.038
mating GO:0007618 1 0.038
regulation of cellular component biogenesis GO:0044087 281 0.038
regulation of blood circulation GO:1903522 59 0.037
Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.037
Human Mouse Rat
positive regulation of cellular catabolic process GO:0031331 284 0.037
regulation of sensory perception of pain GO:0051930 3 0.037
hexose metabolic process GO:0019318 55 0.036
regulation of vascular permeability GO:0043114 11 0.036
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.036
purine containing compound catabolic process GO:0072523 411 0.035
regulation of type b pancreatic cell proliferation GO:0061469 1 0.035
regulation of potassium ion transmembrane transport GO:1901379 20 0.034
divalent metal ion transport GO:0070838 152 0.034
urate transport GO:0015747 3 0.033
regulation of large conductance calcium activated potassium channel activity GO:1902606 2 0.033
acetate ester transport GO:1901374 1 0.033
regulation of cellular component movement GO:0051270 334 0.033
Mouse
glycoprotein metabolic process GO:0009100 110 0.032
opioid receptor signaling pathway GO:0038003 4 0.032
regulation of mapk cascade GO:0043408 262 0.032
Human Rat
postsynaptic membrane organization GO:0001941 2 0.032
immune response GO:0006955 307 0.031
purine nucleoside monophosphate catabolic process GO:0009128 158 0.031
cardiovascular system development GO:0072358 262 0.031
protein localization to membrane GO:0072657 160 0.031
negative regulation of inflammatory response GO:0050728 22 0.031
negative regulation of eosinophil migration GO:2000417 2 0.030
response to hypoxia GO:0001666 96 0.030
Rat
sleep GO:0030431 2 0.030
Rat
camp mediated signaling GO:0019933 23 0.029
detection of stimulus involved in sensory perception GO:0050906 43 0.029
post embryonic development GO:0009791 2 0.029
nucleoside monophosphate catabolic process GO:0009125 159 0.029
regulation of map kinase activity GO:0043405 108 0.029
Human
negative regulation of multicellular organismal process GO:0051241 317 0.029
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
negative regulation of cell growth GO:0030308 83 0.029
behavioral response to ethanol GO:0048149 2 0.029
Mouse
muscle system process GO:0003012 81 0.028
Mouse
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.028
Rat
receptor internalization GO:0031623 43 0.028
Human Rat
cell growth GO:0016049 160 0.028
multicellular organismal aging GO:0010259 3 0.027
regulation of peptide hormone secretion GO:0090276 41 0.027
Mouse Rat
regulation of establishment of endothelial barrier GO:1903140 2 0.027
wnt signaling pathway GO:0016055 156 0.027
Rat
response to lipid GO:0033993 206 0.027
regulation of protein processing GO:0070613 150 0.027
purine nucleoside monophosphate metabolic process GO:0009126 186 0.027
ventral spinal cord development GO:0021517 1 0.026
cell division GO:0051301 168 0.026
vasculature development GO:0001944 181 0.026
positive regulation of mapk cascade GO:0043410 190 0.026
Human Rat
regulation of cation channel activity GO:2001257 33 0.026
negative regulation of cell migration GO:0030336 102 0.025
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.025
regulation of kinase activity GO:0043549 314 0.025
Human Rat
regulation of insulin secretion GO:0050796 33 0.025
Rat
renal tubular secretion GO:0097254 1 0.025
regulation of cellular response to stress GO:0080135 244 0.024
positive regulation of transporter activity GO:0032411 32 0.024
Human
purine ribonucleotide catabolic process GO:0009154 404 0.024
regulation of endothelial cell development GO:1901550 2 0.024
segmentation GO:0035282 4 0.024
regulation of neuron death GO:1901214 56 0.024
regulation of anion transport GO:0044070 25 0.024
cellular response to endogenous stimulus GO:0071495 336 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
Mouse
regulation of cell growth GO:0001558 135 0.024
regulation of cell differentiation GO:0045595 393 0.024
Mouse
diencephalon development GO:0021536 6 0.024
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.023
positive regulation of nucleoside metabolic process GO:0045979 186 0.023
homeostasis of number of cells in a free living population GO:0048874 1 0.023
stem cell development GO:0048864 69 0.023
blood vessel development GO:0001568 172 0.023
gtp catabolic process GO:0006184 237 0.023
amine metabolic process GO:0009308 44 0.023
positive regulation of circadian rhythm GO:0042753 1 0.023
neuron death GO:0070997 65 0.023
circulatory system development GO:0072359 262 0.023
cellular response to oxygen containing compound GO:1901701 276 0.023
blood vessel morphogenesis GO:0048514 162 0.023
sphingolipid mediated signaling pathway GO:0090520 1 0.023
protein catabolic process GO:0030163 325 0.023
peptide hormone secretion GO:0030072 50 0.023
Mouse Rat
spinal cord dorsal ventral patterning GO:0021513 2 0.022
oogenesis GO:0048477 2 0.022
regulation of nucleotide catabolic process GO:0030811 205 0.022
cell adhesion GO:0007155 325 0.022
peptidyl serine phosphorylation GO:0018105 101 0.022

DRD2 disease predictions

Disease DO term ID Size Probability Func Analog Org
substance related disorder DOID:303 10 1.000
disease of mental health DOID:150 70 1.000
Human
substance dependence DOID:9973 10 0.937
sensory system disease DOID:0050155 203 0.046
nervous system disease DOID:863 431 0.046