|
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
1.000
|
|
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.999
|
Fly |
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.999
|
Fly |
|
|
heart induction
|
GO:0003129 |
4 |
0.999
|
Fly |
|
|
cardiac cell fate specification
|
GO:0060912 |
1 |
0.997
|
Fly |
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.995
|
Fly |
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.987
|
Fly |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.982
|
Fly |
|
|
organ formation
|
GO:0048645 |
3 |
0.979
|
Fly |
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.978
|
Fly |
|
|
negative regulation of heart induction by canonical wnt signaling pathway
|
GO:0003136 |
1 |
0.977
|
Fly |
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
2 |
0.977
|
Human |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.972
|
Worm |
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.970
|
|
|
|
non canonical wnt signaling pathway via jnk cascade
|
GO:0038031 |
3 |
0.964
|
|
|
|
cardioblast cell fate commitment
|
GO:0042684 |
1 |
0.962
|
Fly |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.958
|
Fly |
|
|
heart field specification
|
GO:0003128 |
2 |
0.957
|
|
|
|
cardioblast cell fate specification
|
GO:0042685 |
1 |
0.949
|
Fly |
|
|
establishment of apical basal cell polarity
|
GO:0035089 |
1 |
0.929
|
Fly |
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.928
|
Fly |
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.928
|
Fly |
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.925
|
Fly |
|
|
establishment or maintenance of monopolar cell polarity
|
GO:0061339 |
1 |
0.919
|
Fly |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.915
|
Fly |
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.899
|
Fly |
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.890
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.877
|
Mouse |
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.869
|
Worm |
|
|
negative regulation of cardioblast cell fate specification
|
GO:0009997 |
1 |
0.866
|
Fly |
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.861
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.860
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.855
|
Fly |
|
|
organ induction
|
GO:0001759 |
4 |
0.851
|
Fly |
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.813
|
Mouse |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.778
|
Fly |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.762
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.762
|
Fly |
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.751
|
Fly |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.739
|
|
|
|
negative regulation of cardiac cell fate specification
|
GO:2000044 |
1 |
0.737
|
Fly |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.731
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.706
|
|
|
|
negative chemotaxis
|
GO:0050919 |
11 |
0.683
|
Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.656
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.638
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.629
|
Worm |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.604
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.604
|
Human |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.600
|
Mouse |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.593
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.590
|
Worm |
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.583
|
Worm |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.582
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.578
|
|
|
|
signal transduction involved in regulation of gene expression
|
GO:0023019 |
1 |
0.557
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.555
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.534
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.527
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.516
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.512
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.510
|
|
|
|
regulation of cardioblast cell fate specification
|
GO:0042686 |
1 |
0.507
|
Fly |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.506
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.487
|
Mouse |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.479
|
|
|
|
negative regulation of heart induction
|
GO:1901320 |
1 |
0.474
|
Fly |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.462
|
|
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
5 |
0.461
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.458
|
Human |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.446
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.439
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.421
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.400
|
Mouse Fly |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.399
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.394
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.391
|
Human Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.386
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.383
|
Fly |
|
|
wnt signaling pathway involved in heart development
|
GO:0003306 |
5 |
0.380
|
Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.377
|
Worm Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.360
|
Human |
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.358
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.355
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.348
|
Human |
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.342
|
Worm |
|
|
epithelium development
|
GO:0060429 |
227 |
0.342
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.336
|
Mouse Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.328
|
Human |
|
|
regulation of kidney size
|
GO:0035564 |
2 |
0.318
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.309
|
Fly |
|
|
neural tube closure
|
GO:0001843 |
3 |
0.309
|
Mouse |
|
|
endoderm development
|
GO:0007492 |
33 |
0.309
|
Worm |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.308
|
Human |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.295
|
Worm |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.291
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.286
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.284
|
Mouse Worm |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.281
|
Human |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.280
|
Worm |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.280
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.275
|
Mouse Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.271
|
Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.265
|
Human |
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.261
|
Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.257
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.256
|
Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.253
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.250
|
Mouse Fly |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.246
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.245
|
Mouse Fly |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.245
|
Fly |
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.243
|
Fly |
|
|
tube closure
|
GO:0060606 |
3 |
0.242
|
Mouse |
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.237
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.237
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.235
|
Human |
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.233
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.229
|
Worm |
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.228
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.228
|
Mouse Fly |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.225
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.223
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.221
|
Human |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.216
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.214
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.213
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.211
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.210
|
Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.208
|
Human |
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.206
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.204
|
Worm |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.201
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.200
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.195
|
Worm Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.193
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.192
|
Fly |
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.190
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.180
|
Mouse |
|
|
nervous system development
|
GO:0007399 |
293 |
0.178
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.178
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.176
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.176
|
Fly |
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.173
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.173
|
Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.172
|
Human |
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.172
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.167
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.166
|
Worm |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.165
|
Fly |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.163
|
Mouse |
|
|
stem cell development
|
GO:0048864 |
69 |
0.162
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.162
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.160
|
Mouse |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.158
|
Mouse Worm Fly |
|
|
establishment of epithelial cell polarity
|
GO:0090162 |
2 |
0.157
|
Fly |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.157
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.156
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.156
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.153
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.152
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.148
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.147
|
Mouse Fly |
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
8 |
0.147
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.147
|
Mouse Worm |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.145
|
Worm |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.144
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.144
|
|
|
|
negative regulation of cardioblast differentiation
|
GO:0051892 |
2 |
0.142
|
Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.141
|
Mouse Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.140
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.138
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.138
|
Mouse Fly |
|
|
regulation of peroxidase activity
|
GO:2000468 |
2 |
0.136
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.136
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.136
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.132
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.132
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.131
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.131
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.130
|
Fly |
|
|
inner ear development
|
GO:0048839 |
8 |
0.130
|
Mouse |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.129
|
Fly |
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.128
|
Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.128
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.124
|
Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.122
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.122
|
Mouse Worm |
|
|
neuron development
|
GO:0048666 |
113 |
0.121
|
Mouse Fly |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.120
|
Mouse Fly |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.117
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.117
|
Mouse Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.117
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.116
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.114
|
Mouse Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.114
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.112
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.112
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.112
|
|
|
|
skin morphogenesis
|
GO:0043589 |
6 |
0.112
|
Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.111
|
Human |
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.111
|
Mouse Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.111
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.111
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.110
|
|
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
7 |
0.108
|
Worm |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.108
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.107
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.104
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.103
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.103
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.103
|
Mouse |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.103
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.100
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.100
|
Fly |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.100
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.099
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.099
|
Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.099
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.099
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.098
|
Mouse Fly |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.098
|
Mouse |
|
|
steroid hormone secretion
|
GO:0035929 |
8 |
0.096
|
|
|
|
regulation of establishment or maintenance of cell polarity
|
GO:0032878 |
7 |
0.096
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.096
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.095
|
Mouse Fly |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.094
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.093
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.092
|
|
|
|
trna wobble uridine modification
|
GO:0002098 |
3 |
0.091
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.091
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.091
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.091
|
Worm |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.091
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.090
|
Worm |
|
|
digestive system development
|
GO:0055123 |
75 |
0.090
|
Worm |
|
|
cellular response to ammonium ion
|
GO:0071242 |
4 |
0.088
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.088
|
|
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.087
|
Fly |
|
|
organelle localization
|
GO:0051640 |
84 |
0.086
|
Worm |
|
|
negative regulation of glomerulus development
|
GO:0090194 |
2 |
0.085
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.085
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.084
|
Worm |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.084
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.083
|
Mouse |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.083
|
Worm |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.082
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.081
|
Human |
|
|
regulation of synaptic vesicle endocytosis
|
GO:1900242 |
1 |
0.081
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.081
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.081
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.080
|
Mouse Worm Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.080
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.080
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.080
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.079
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.079
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.078
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.078
|
Mouse |
|
|
negative regulation of notch signaling pathway
|
GO:0045746 |
10 |
0.076
|
Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.076
|
Mouse Fly |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.076
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.076
|
|
|
|
negative regulation of kidney development
|
GO:0090185 |
2 |
0.076
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.075
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.073
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.072
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.072
|
Mouse Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.070
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.070
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.070
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.068
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.068
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.068
|
Worm |
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.068
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.067
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.067
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.067
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.067
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.066
|
|
|
|
developmental induction
|
GO:0031128 |
5 |
0.065
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.065
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.065
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.065
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.065
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.064
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.064
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.064
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.064
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.062
|
Mouse Worm |
|
|
diaphragm development
|
GO:0060539 |
2 |
0.062
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.062
|
Fly |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.062
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.062
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.060
|
Mouse Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.060
|
|
|
|
growth
|
GO:0040007 |
202 |
0.060
|
Mouse Fly |
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.059
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.058
|
Fly |
|
|
regulation of male gonad development
|
GO:2000018 |
4 |
0.058
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.058
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.058
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.058
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.057
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.057
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.057
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.055
|
|
|
|
ear development
|
GO:0043583 |
14 |
0.055
|
Mouse |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.055
|
|
|
|
cardioblast differentiation
|
GO:0010002 |
8 |
0.054
|
Fly |
|
|
protein targeting
|
GO:0006605 |
187 |
0.054
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.054
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.053
|
Fly |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.053
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.052
|
|
|
|
ear morphogenesis
|
GO:0042471 |
7 |
0.050
|
Mouse |
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.050
|
Worm |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.050
|
|
|
|
tangential migration from the subventricular zone to the olfactory bulb
|
GO:0022028 |
3 |
0.050
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.050
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.049
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.049
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.049
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.049
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.049
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.048
|
Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.048
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.048
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.047
|
|
|
|
neuroendocrine cell differentiation
|
GO:0061101 |
2 |
0.047
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.047
|
Worm Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.047
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.047
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.047
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.046
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.046
|
Mouse |
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.046
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.046
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.045
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.045
|
|
|
|
negative regulation of cell proliferation involved in kidney development
|
GO:1901723 |
2 |
0.045
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.045
|
Mouse Fly |
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.044
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.044
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.044
|
Mouse |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.044
|
|
|
|
positive regulation of male gonad development
|
GO:2000020 |
3 |
0.044
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.043
|
Mouse Fly |
|
|
cilium organization
|
GO:0044782 |
68 |
0.043
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.043
|
|
|
|
head development
|
GO:0060322 |
108 |
0.043
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.042
|
Mouse Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.042
|
Human Mouse |
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.042
|
Fly |
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.041
|
Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.041
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.041
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.040
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.040
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.040
|
Fly |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.040
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.040
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.039
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.039
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.039
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.039
|
Mouse Fly |
|
|
nephron morphogenesis
|
GO:0072028 |
15 |
0.039
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.039
|
|
|
|
cardiac septum development
|
GO:0003279 |
13 |
0.039
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.039
|
|
|
|
regulation of synaptic vesicle recycling
|
GO:1903421 |
1 |
0.038
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.038
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.038
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.037
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.037
|
Worm |
|
|
protein import
|
GO:0017038 |
130 |
0.037
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.037
|
|
|
|
endocrine process
|
GO:0050886 |
25 |
0.036
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.036
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
10 |
0.036
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.036
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.036
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.036
|
Mouse |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.036
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.036
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
15 |
0.036
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.036
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.035
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.035
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.035
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.035
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.035
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.034
|
Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.034
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.034
|
Mouse Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.034
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.034
|
Fly |
|
|
trna processing
|
GO:0008033 |
23 |
0.034
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.034
|
|
|
|
positive regulation of mesonephros development
|
GO:0061213 |
2 |
0.034
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.034
|
Worm Fly |
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.033
|
Mouse Fly |
|
|
endocrine hormone secretion
|
GO:0060986 |
13 |
0.033
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.033
|
Mouse Fly |
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.033
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.033
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.033
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.033
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.033
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.033
|
Mouse |
|
|
tube formation
|
GO:0035148 |
10 |
0.033
|
Mouse |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.033
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.032
|
Human |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.032
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.032
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.032
|
Mouse Fly |
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.032
|
|
|
|
nephric duct development
|
GO:0072176 |
4 |
0.032
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.032
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.031
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.031
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.031
|
Mouse Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.031
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.031
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.031
|
Mouse |
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.031
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.031
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.031
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.030
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.030
|
Fly |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.030
|
Human |
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.030
|
|
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.030
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.030
|
Mouse |
|
|
ncrna processing
|
GO:0034470 |
83 |
0.030
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.030
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.030
|
Fly |
|
|
metencephalon development
|
GO:0022037 |
2 |
0.029
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.029
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.029
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.029
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.029
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.029
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.029
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.028
|
|
|
|
negative regulation of glomerular mesangial cell proliferation
|
GO:0072125 |
2 |
0.028
|
|
|
|
metanephric nephron tubule morphogenesis
|
GO:0072282 |
1 |
0.028
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.028
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.028
|
Fly |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.028
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.028
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.027
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.027
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.027
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.027
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.027
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.027
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.026
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.026
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.026
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.026
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.026
|
Mouse |
|
|
neural plate regionalization
|
GO:0060897 |
1 |
0.026
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.026
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.026
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
8 |
0.026
|
Worm |
|
|
gland development
|
GO:0048732 |
48 |
0.026
|
Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.025
|
Fly |
|
|
cochlea morphogenesis
|
GO:0090103 |
1 |
0.025
|
Mouse |
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.025
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.025
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.025
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.025
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.025
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.025
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.025
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.025
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.024
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.024
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.024
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.024
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.024
|
|
