Homo sapiens

20 known processes

DYRK1A

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

(Aliases: DYRK,DYRK1,HP86,MNB,MNBH)

DYRK1A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.997
regulation of cell differentiation GO:0045595 393 0.985
embryonic camera type eye morphogenesis GO:0048596 2 0.980
negative regulation of phagocytosis GO:0050765 4 0.949
oxidation reduction process GO:0055114 396 0.914
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.909
ras protein signal transduction GO:0007265 73 0.875
regulation of cellular component size GO:0032535 82 0.869
apoptotic signaling pathway GO:0097190 268 0.826
Human
cell morphogenesis involved in differentiation GO:0000904 144 0.824
positive regulation of developmental process GO:0051094 314 0.773
morphogenesis of embryonic epithelium GO:0016331 4 0.753
erythrocyte differentiation GO:0030218 28 0.746
Human
small gtpase mediated signal transduction GO:0007264 78 0.746
regulation of hippo signaling GO:0035330 8 0.745
regulation of ras protein signal transduction GO:0046578 155 0.737
cellular response to dna damage stimulus GO:0006974 379 0.727
Human Mouse
cell development GO:0048468 328 0.724
peptidyl lysine modification GO:0018205 144 0.687
erythrocyte homeostasis GO:0034101 31 0.667
Human
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.663
oogenesis GO:0048477 2 0.622
kidney development GO:0001822 53 0.620
rho protein signal transduction GO:0007266 26 0.613
cellular carbohydrate metabolic process GO:0044262 84 0.597
Human
energy reserve metabolic process GO:0006112 22 0.597
Human
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.589
Human
generation of precursor metabolites and energy GO:0006091 68 0.580
Human
regulation of cell cycle process GO:0010564 266 0.577
cellular glucan metabolic process GO:0006073 22 0.567
Human
positive regulation of glycogen biosynthetic process GO:0045725 10 0.564
Human
regulation of phagocytosis engulfment GO:0060099 2 0.551
negative regulation of cell cycle GO:0045786 193 0.541
epithelial cell differentiation GO:0030855 141 0.535
connective tissue development GO:0061448 39 0.529
Human
myoblast fusion GO:0007520 1 0.528
regulation of anatomical structure size GO:0090066 101 0.522
female gamete generation GO:0007292 2 0.506
immune system development GO:0002520 195 0.503
Human
regulation of gtp catabolic process GO:0033124 180 0.501
multicellular organismal aging GO:0010259 3 0.490
glucan metabolic process GO:0044042 22 0.489
Human
segmentation GO:0035282 4 0.489
regulation of nucleoside metabolic process GO:0009118 209 0.486
regulation of neuron differentiation GO:0045664 70 0.481
organ morphogenesis GO:0009887 147 0.478
positive regulation of glucose metabolic process GO:0010907 12 0.471
Human
muscle structure development GO:0061061 98 0.470
neuron differentiation GO:0030182 138 0.469
positive regulation of cell proliferation GO:0008284 301 0.465
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.459
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.459
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.457
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.455
regulation of purine nucleotide catabolic process GO:0033121 205 0.443
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.442
cell morphogenesis GO:0000902 296 0.441
regulation of neuron projection development GO:0010975 57 0.440
blastoderm segmentation GO:0007350 2 0.440
regulation of glucose metabolic process GO:0010906 28 0.438
Human
neuron projection development GO:0031175 106 0.434
cell cell signaling GO:0007267 155 0.434
guanosine containing compound catabolic process GO:1901069 239 0.433
regulation of gtpase activity GO:0043087 180 0.413
cellular component morphogenesis GO:0032989 314 0.400
retina layer formation GO:0010842 3 0.397
regulation of cell motility GO:2000145 299 0.392
regulation of nervous system development GO:0051960 88 0.389
adipose tissue development GO:0060612 2 0.384
Human
regulation of generation of precursor metabolites and energy GO:0043467 27 0.377
Human
regulation of rho gtpase activity GO:0032319 66 0.369
wnt signaling pathway GO:0016055 156 0.365
myeloid cell differentiation GO:0030099 117 0.350
Human
homeostasis of number of cells GO:0048872 40 0.349
Human
nervous system development GO:0007399 293 0.343
positive regulation of cellular catabolic process GO:0031331 284 0.343
internal protein amino acid acetylation GO:0006475 101 0.341
cell projection morphogenesis GO:0048858 129 0.333
microtubule cytoskeleton organization GO:0000226 176 0.326
regulation of axonogenesis GO:0050770 16 0.325
embryo development GO:0009790 123 0.323
renal system development GO:0072001 63 0.319
positive regulation of cell differentiation GO:0045597 211 0.318
regulation of nucleocytoplasmic transport GO:0046822 98 0.312
Human
regulation of cell development GO:0060284 161 0.307
axon cargo transport GO:0008088 2 0.303
regulation of cell morphogenesis GO:0022604 153 0.302
associative learning GO:0008306 1 0.295
epithelium development GO:0060429 227 0.290
negative regulation of wnt signaling pathway GO:0030178 69 0.286
positive regulation of feeding behavior GO:2000253 1 0.284
internal peptidyl lysine acetylation GO:0018393 97 0.284
monosaccharide metabolic process GO:0005996 74 0.284
Human
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.283
cell projection organization GO:0030030 252 0.282
carbohydrate biosynthetic process GO:0016051 42 0.277
Human
regulation of cell cycle GO:0051726 393 0.276
cellular polysaccharide biosynthetic process GO:0033692 21 0.270
Human
formation of primary germ layer GO:0001704 42 0.268
purine nucleotide catabolic process GO:0006195 405 0.268
mitochondrion organization GO:0007005 156 0.264
digestive tract morphogenesis GO:0048546 56 0.263
positive regulation of carbohydrate metabolic process GO:0045913 21 0.262
Human
smoothened signaling pathway GO:0007224 14 0.262
Human
positive regulation of cellular carbohydrate metabolic process GO:0010676 16 0.253
Human
regulation of protein catabolic process GO:0042176 155 0.251
regulation of feeding behavior GO:0060259 3 0.249
extrinsic apoptotic signaling pathway GO:0097191 119 0.248
hematopoietic or lymphoid organ development GO:0048534 186 0.247
Human
negative regulation of transport GO:0051051 176 0.246
Human
organophosphate catabolic process GO:0046434 430 0.244
cellular response to endogenous stimulus GO:0071495 336 0.243
myotube differentiation GO:0014902 22 0.242
regulation of polysaccharide biosynthetic process GO:0032885 20 0.242
Human
myeloid cell homeostasis GO:0002262 34 0.241
Human
protein catabolic process GO:0030163 325 0.241
regulation of cellular component movement GO:0051270 334 0.238
cell part morphogenesis GO:0032990 137 0.238
skeletal system development GO:0001501 79 0.237
hemopoiesis GO:0030097 180 0.235
Human
vasculature development GO:0001944 181 0.235
regulation of proteasomal protein catabolic process GO:0061136 87 0.230
cytoplasmic transport GO:0016482 379 0.228
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.226
histone acetylation GO:0016573 93 0.226
embryonic camera type eye development GO:0031076 2 0.225
cell cycle phase transition GO:0044770 173 0.222
response to oxygen containing compound GO:1901700 369 0.222
dna integrity checkpoint GO:0031570 71 0.221
embryonic morphogenesis GO:0048598 85 0.220
cellular response to oxygen containing compound GO:1901701 276 0.217
regulation of cell projection organization GO:0031344 107 0.215
positive regulation of erythrocyte differentiation GO:0045648 11 0.213
neuron development GO:0048666 113 0.210
embryonic retina morphogenesis in camera type eye GO:0060059 1 0.208
regulation of rho protein signal transduction GO:0035023 79 0.208
positive regulation of dna templated transcription elongation GO:0032786 18 0.207
positive regulation of cellular component organization GO:0051130 376 0.206
purine nucleoside catabolic process GO:0006152 398 0.206
cytokine mediated signaling pathway GO:0019221 109 0.202
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.200
ribonucleotide catabolic process GO:0009261 405 0.195
urogenital system development GO:0001655 65 0.186
positive regulation of autophagy GO:0010508 24 0.185
gtp catabolic process GO:0006184 237 0.181
nuclear transport GO:0051169 179 0.181
Human
regulation of protein localization GO:0032880 296 0.179
Human
gtp metabolic process GO:0046039 239 0.178
embryonic eye morphogenesis GO:0048048 2 0.177
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 2 0.177
oocyte development GO:0048599 1 0.177
circadian behavior GO:0048512 2 0.176
negative regulation of protein localization to nucleus GO:1900181 34 0.174
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.172
neuron projection morphogenesis GO:0048812 50 0.168
regulation of purine nucleotide metabolic process GO:1900542 264 0.167
purine nucleoside triphosphate catabolic process GO:0009146 392 0.165
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.165
nucleocytoplasmic transport GO:0006913 176 0.165
Human
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.164
Human
histone modification GO:0016570 251 0.163
covalent chromatin modification GO:0016569 254 0.162
regulation of neural precursor cell proliferation GO:2000177 4 0.162
membrane organization GO:0061024 292 0.162
viral transcription GO:0019083 35 0.160
regulation of locomotion GO:0040012 329 0.156
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.152
protein acetylation GO:0006473 116 0.152
peptidyl serine modification GO:0018209 106 0.152
Mouse Rat
regulation of lipid metabolic process GO:0019216 96 0.151
chromatin modification GO:0016568 298 0.151
regulation of glycogen metabolic process GO:0070873 15 0.150
Human
cellular response to external stimulus GO:0071496 111 0.149
protein acylation GO:0043543 138 0.149
cellular response to growth factor stimulus GO:0071363 197 0.146
protein import into nucleus GO:0006606 104 0.146
Human
neurogenesis GO:0022008 169 0.144
cellular carbohydrate biosynthetic process GO:0034637 21 0.140
Human
kidney morphogenesis GO:0060993 19 0.140
positive regulation of protein catabolic process GO:0045732 75 0.139
neurological system process GO:0050877 163 0.137
response to hypoxia GO:0001666 96 0.136
negative regulation of phosphorylation GO:0042326 174 0.135
anatomical structure formation involved in morphogenesis GO:0048646 284 0.135
negative regulation of cell death GO:0060548 345 0.134
regulation of mitotic cell cycle phase transition GO:1901990 118 0.132
positive regulation of growth GO:0045927 58 0.132
regulation of cytoplasmic transport GO:1903649 149 0.131
Human
regulation of erythrocyte differentiation GO:0045646 17 0.128
regulation of protein localization to nucleus GO:1900180 85 0.127
Human
purine containing compound catabolic process GO:0072523 411 0.126
tube development GO:0035295 125 0.125
post embryonic development GO:0009791 2 0.125
regulation of ras gtpase activity GO:0032318 128 0.125
regulation of growth GO:0040008 165 0.125
cell type specific apoptotic process GO:0097285 125 0.124
regulation of nucleotide metabolic process GO:0006140 269 0.124
negative regulation of cellular component organization GO:0051129 235 0.124
regulation of cellular ketone metabolic process GO:0010565 50 0.123
purine ribonucleotide catabolic process GO:0009154 404 0.123
digestive system development GO:0055123 75 0.122
regulation of intracellular protein transport GO:0033157 123 0.120
Human
regulation of protein kinase activity GO:0045859 289 0.120
rac protein signal transduction GO:0016601 12 0.113
regulation of multi organism process GO:0043900 157 0.112
stem cell development GO:0048864 69 0.111
blood circulation GO:0008015 113 0.110
mitotic cell cycle process GO:1903047 286 0.110
embryonic organ morphogenesis GO:0048562 24 0.109
negative regulation of catalytic activity GO:0043086 335 0.108
cellular protein catabolic process GO:0044257 261 0.108
regulation of neurogenesis GO:0050767 82 0.108
regulation of wnt signaling pathway GO:0030111 123 0.107
negative regulation of phosphorus metabolic process GO:0010563 267 0.107
positive regulation of cellular component biogenesis GO:0044089 158 0.107
lung development GO:0030324 20 0.107
negative regulation of g0 to g1 transition GO:0070317 2 0.106
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.106
gastrulation GO:0007369 51 0.106
signal transduction by p53 class mediator GO:0072331 72 0.105
Human Mouse
posttranscriptional regulation of gene expression GO:0010608 213 0.105
anterior posterior axis specification GO:0009948 2 0.104
embryonic organ development GO:0048568 36 0.104
negative regulation of locomotion GO:0040013 118 0.104
peptide transport GO:0015833 74 0.104
positive regulation of programmed cell death GO:0043068 249 0.103
behavior GO:0007610 112 0.103
anterior posterior axis specification embryo GO:0008595 2 0.103
microtubule based process GO:0007017 210 0.102
glycosyl compound catabolic process GO:1901658 413 0.102
regulation of protein targeting GO:1903533 91 0.102
Human
response to hyperoxia GO:0055093 4 0.101
ribonucleoside triphosphate catabolic process GO:0009203 391 0.101
positive regulation of stress activated mapk cascade GO:0032874 60 0.097
regulation of nucleotide catabolic process GO:0030811 205 0.097
regulation of cell migration GO:0030334 289 0.097
epidermal cell differentiation GO:0009913 45 0.095
cell growth GO:0016049 160 0.095
hippo signaling GO:0035329 20 0.094
regulation of epithelial cell differentiation GO:0030856 24 0.094
regulation of carbohydrate biosynthetic process GO:0043255 27 0.094
Human
mitotic cell cycle phase transition GO:0044772 162 0.093
locomotory behavior GO:0007626 1 0.093
nucleoside triphosphate catabolic process GO:0009143 394 0.092
negative regulation of multicellular organismal process GO:0051241 317 0.092
regulation of viral process GO:0050792 103 0.092
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.090
regulation of cellular amine metabolic process GO:0033238 11 0.089
ribonucleoside catabolic process GO:0042454 406 0.088
tripartite regional subdivision GO:0007351 2 0.088
negative regulation of programmed cell death GO:0043069 321 0.087
regulation of developmental pigmentation GO:0048070 2 0.087
i kappab kinase nf kappab signaling GO:0007249 166 0.086
regulation of mrna stability GO:0043488 23 0.086
mating GO:0007618 1 0.085
regulation of canonical wnt signaling pathway GO:0060828 88 0.084
dna damage checkpoint GO:0000077 68 0.084
negative regulation of cellular component movement GO:0051271 106 0.083
regulation of mapk cascade GO:0043408 262 0.083
positive regulation of apoptotic process GO:0043065 246 0.083
tube morphogenesis GO:0035239 95 0.082
negative regulation of phosphate metabolic process GO:0045936 267 0.081
axon development GO:0061564 34 0.081
axonogenesis GO:0007409 31 0.080
positive regulation of multi organism process GO:0043902 56 0.079
protein targeting to nucleus GO:0044744 104 0.079
Human
circulatory system development GO:0072359 262 0.079
mitotic cell cycle GO:0000278 326 0.078
organelle fission GO:0048285 149 0.077
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.077
circulatory system process GO:0003013 113 0.077
ameboidal type cell migration GO:0001667 135 0.077
regulation of cell growth GO:0001558 135 0.077
epithelial cell development GO:0002064 34 0.076
macroautophagy GO:0016236 39 0.076
cellular ketone metabolic process GO:0042180 80 0.076
oocyte differentiation GO:0009994 2 0.075
memory GO:0007613 3 0.074
regulation of actin filament based process GO:0032970 141 0.074
regulation of establishment of protein localization GO:0070201 242 0.073
Human
regulation of vasculature development GO:1901342 97 0.072
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.072
somatic muscle development GO:0007525 1 0.072
columnar cuboidal epithelial cell differentiation GO:0002065 14 0.072
camp biosynthetic process GO:0006171 47 0.071
endoderm development GO:0007492 33 0.071
tissue regeneration GO:0042246 3 0.070
positive regulation of ras gtpase activity GO:0032320 117 0.069
cellular response to cytokine stimulus GO:0071345 181 0.069
polysaccharide biosynthetic process GO:0000271 27 0.069
Human
regulation of dna templated transcription elongation GO:0032784 23 0.069
protein localization to organelle GO:0033365 280 0.068
Human
negative regulation of mitotic cell cycle GO:0045930 102 0.068
regulation of developmental growth GO:0048638 30 0.068
protein localization to nucleus GO:0034504 136 0.068
Human
regulation of protein complex assembly GO:0043254 147 0.067
positive regulation of proteolysis GO:0045862 142 0.067
ribonucleoside triphosphate metabolic process GO:0009199 412 0.067
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.066
regulation of stress activated mapk cascade GO:0032872 84 0.066
nucleoside triphosphate metabolic process GO:0009141 422 0.066
blood vessel development GO:0001568 172 0.064
angiogenesis GO:0001525 147 0.064
negative regulation of cell migration GO:0030336 102 0.064
single organism reproductive process GO:0044702 98 0.064
nucleoside phosphate catabolic process GO:1901292 412 0.064
lens development in camera type eye GO:0002088 2 0.063
regulation of cellular protein catabolic process GO:1903362 96 0.063
negative regulation of phagocytosis engulfment GO:0060101 1 0.063
cellular response to extracellular stimulus GO:0031668 72 0.063
protein targeting GO:0006605 187 0.062
Human
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.062
regulation of protein transport GO:0051223 213 0.062
Human
activation of jnkk activity GO:0007256 1 0.061
positive regulation of viral process GO:0048524 37 0.061
response to cytokine GO:0034097 232 0.061
negative regulation of cell cycle process GO:0010948 121 0.061
rna stabilization GO:0043489 18 0.061
potassium ion transport GO:0006813 62 0.060
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.060
cell cycle checkpoint GO:0000075 117 0.060
dna templated transcription initiation GO:0006352 35 0.060
regulation of reactive oxygen species metabolic process GO:2000377 41 0.060
regulation of kinase activity GO:0043549 314 0.060
glucan biosynthetic process GO:0009250 16 0.060
Human
single organism cellular localization GO:1902580 332 0.059
Human
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.059
mitotic dna integrity checkpoint GO:0044774 30 0.059
response to abiotic stimulus GO:0009628 336 0.059
negative regulation of cell growth GO:0030308 83 0.059
negative regulation of nfat protein import into nucleus GO:0051534 2 0.058
Human
peptidyl tyrosine modification GO:0018212 170 0.058
cyclic purine nucleotide metabolic process GO:0052652 60 0.058
carbon catabolite activation of transcription GO:0045991 3 0.058
cartilage development GO:0051216 31 0.057
ribose phosphate biosynthetic process GO:0046390 82 0.057
muscle cell differentiation GO:0042692 63 0.056
cellular amine metabolic process GO:0044106 41 0.056
growth GO:0040007 202 0.055
cellular response to nitrogen compound GO:1901699 144 0.054
peptidyl tyrosine phosphorylation GO:0018108 170 0.054
nfat protein import into nucleus GO:0051531 5 0.054
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.054
positive regulation of neurogenesis GO:0050769 49 0.054
positive regulation of cell cycle process GO:0090068 106 0.054
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.053
primary neural tube formation GO:0014020 3 0.053
positive regulation of myeloid cell differentiation GO:0045639 39 0.052
hexose metabolic process GO:0019318 55 0.052
Human
negative regulation of lipid metabolic process GO:0045833 38 0.052
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.052
negative regulation of cytoskeleton organization GO:0051494 45 0.052
positive regulation of transcription by galactose GO:0000411 1 0.052
somatic stem cell maintenance GO:0035019 4 0.052
generation of neurons GO:0048699 152 0.052
neural crest cell development GO:0014032 3 0.052
cellular macromolecular complex assembly GO:0034622 324 0.050
cellular response to starvation GO:0009267 58 0.050
positive regulation of neuron differentiation GO:0045666 40 0.050
negative regulation of cytoplasmic transport GO:1903650 46 0.050
Human
eyelid development in camera type eye GO:0061029 2 0.049
regulation of mitosis GO:0007088 63 0.049
developmental growth GO:0048589 48 0.049
intracellular protein transport GO:0006886 270 0.049
Human
regulation of nuclear division GO:0051783 65 0.048
regulation of cellular response to stress GO:0080135 244 0.048
Mouse
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.048
regulation of g0 to g1 transition GO:0070316 2 0.048
monovalent inorganic cation transport GO:0015672 128 0.047
regulation of fibroblast proliferation GO:0048145 32 0.047
regulation of small gtpase mediated signal transduction GO:0051056 156 0.047
regulation of extent of cell growth GO:0061387 9 0.047
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.047
endosomal transport GO:0016197 129 0.047
regulation of proteolysis GO:0030162 293 0.047
cellular response to hypoxia GO:0071456 51 0.047
activin receptor signaling pathway GO:0032924 24 0.047
positive regulation of cell death GO:0010942 263 0.047
positive regulation of multicellular organism growth GO:0040018 6 0.046
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.046
neuron projection extension GO:1990138 14 0.046
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 3 0.045
chemical homeostasis GO:0048878 306 0.045
regionalization GO:0003002 29 0.045
cell division GO:0051301 168 0.044
protein import GO:0017038 130 0.044
Human
regulation of rac gtpase activity GO:0032314 4 0.044
multi organism metabolic process GO:0044033 41 0.044
regulation of homeostatic process GO:0032844 121 0.043
regulation of carbohydrate metabolic process GO:0006109 54 0.043
Human
regulation of lipid kinase activity GO:0043550 19 0.043
positive regulation of developmental growth GO:0048639 16 0.043
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.043
cellular lipid metabolic process GO:0044255 303 0.043
establishment of protein localization to organelle GO:0072594 172 0.043
Human
cardiovascular system development GO:0072358 262 0.043
compound eye development GO:0048749 1 0.043
regulation of system process GO:0044057 101 0.043
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.042
regulation of cell size GO:0008361 19 0.042
positive regulation of protein phosphorylation GO:0001934 313 0.042
taxis GO:0042330 157 0.042
regulation of dendrite morphogenesis GO:0048814 11 0.042
regulation of cytokine production GO:0001817 232 0.041
response to transforming growth factor beta GO:0071559 94 0.041
intrinsic apoptotic signaling pathway GO:0097193 127 0.040
Human
hormone transport GO:0009914 68 0.040
lipid metabolic process GO:0006629 381 0.040
negative regulation of cell motility GO:2000146 104 0.040
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.040
Human
negative regulation of gliogenesis GO:0014014 3 0.039
positive regulation of gluconeogenesis GO:0045722 1 0.039
nitrogen compound transport GO:0071705 191 0.038
positive regulation of cell development GO:0010720 92 0.038
post embryonic organ development GO:0048569 1 0.038
developmental cell growth GO:0048588 18 0.038
nephron development GO:0072006 30 0.038
central nervous system development GO:0007417 123 0.037
long term synaptic potentiation GO:0060291 1 0.037
nucleotide catabolic process GO:0009166 408 0.037
regulation of rna stability GO:0043487 23 0.037
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.037
pigmentation GO:0043473 22 0.037
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.037
purine ribonucleoside metabolic process GO:0046128 437 0.037
striated muscle cell differentiation GO:0051146 43 0.036
translation GO:0006412 132 0.036
glycogen metabolic process GO:0005977 22 0.036
Human
regulation of dna templated transcription in response to stress GO:0043620 18 0.036
embryonic epithelial tube formation GO:0001838 4 0.035
regulation of apoptotic signaling pathway GO:2001233 175 0.035
positive regulation of nucleotide metabolic process GO:0045981 230 0.035
regulation of growth rate GO:0040009 1 0.034
hair cell differentiation GO:0035315 2 0.034
positive regulation of protein complex assembly GO:0031334 86 0.034
regulation of blood circulation GO:1903522 59 0.034
epithelial cell morphogenesis GO:0003382 8 0.034
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.034
tissue migration GO:0090130 119 0.033
cell adhesion GO:0007155 325 0.033
methylation GO:0032259 106 0.033
negative regulation of bmp signaling pathway GO:0030514 17 0.033
positive regulation of hormone biosynthetic process GO:0046886 4 0.033
positive regulation of glycogen metabolic process GO:0070875 10 0.033
Human
protein deacetylation GO:0006476 38 0.032
Mouse
photoreceptor cell differentiation GO:0046530 2 0.032
lens morphogenesis in camera type eye GO:0002089 2 0.032
regulation of angiogenesis GO:0045765 92 0.032
stress activated protein kinase signaling cascade GO:0031098 94 0.032
negative regulation of protein transport GO:0051224 75 0.032
Human
regulation of multicellular organism growth GO:0040014 8 0.032
regulation of dendrite development GO:0050773 18 0.032
maintenance of location GO:0051235 112 0.032
developmental process involved in reproduction GO:0003006 66 0.031
single organism behavior GO:0044708 28 0.031
cell cycle arrest GO:0007050 71 0.031
cellular macromolecule catabolic process GO:0044265 380 0.031
regulation of protein maturation GO:1903317 150 0.031
mesenchymal cell development GO:0014031 50 0.031
melanocyte differentiation GO:0030318 2 0.031
stress activated mapk cascade GO:0051403 93 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.030
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.030
cell differentiation involved in kidney development GO:0061005 9 0.030
negative regulation of intracellular signal transduction GO:1902532 183 0.030
Mouse
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.030
negative regulation of smoothened signaling pathway GO:0045879 3 0.030
peptidyl threonine phosphorylation GO:0018107 41 0.029
Mouse
mitotic dna damage checkpoint GO:0044773 28 0.029
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.029
dendrite development GO:0016358 24 0.029
positive regulation of rho gtpase activity GO:0032321 56 0.028
reproductive process GO:0022414 106 0.028
protein polyubiquitination GO:0000209 110 0.028
cellular response to mechanical stimulus GO:0071260 39 0.028
organ formation GO:0048645 3 0.028
regulation of hormone levels GO:0010817 125 0.028
regulation of notch signaling pathway GO:0008593 18 0.028
amine metabolic process GO:0009308 44 0.028
canonical wnt signaling pathway GO:0060070 116 0.028
neuron death GO:0070997 65 0.028
embryonic hemopoiesis GO:0035162 4 0.028
regulation of cell cycle g1 s phase transition GO:1902806 42 0.027
ubiquitin dependent protein catabolic process GO:0006511 206 0.027
microtubule based movement GO:0007018 32 0.027

DYRK1A disease predictions

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 41 0.855
Human
central nervous system disease DOID:331 186 0.855
Human
brain disease DOID:936 73 0.855
Human
electroclinical syndrome DOID:0050701 32 0.855
Human
nervous system disease DOID:863 431 0.855
Human
disease of cellular proliferation DOID:14566 174 0.061
chromosomal disease DOID:0080014 16 0.036
gonadal dysgenesis DOID:14447 8 0.036
46 xy gonadal dysgenesis DOID:14448 8 0.036
cancer DOID:162 167 0.033