|
|
chromatin modification
|
GO:0016568 |
298 |
0.992
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.981
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.881
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.863
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.861
|
Human Fly |
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.838
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
0.837
|
Human |
|
|
histone h3 k9 modification
|
GO:0061647 |
11 |
0.803
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.698
|
Human |
|
|
methylation
|
GO:0032259 |
106 |
0.684
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.627
|
|
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.570
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.559
|
Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.496
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.466
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.464
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.461
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.455
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.447
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.427
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.427
|
|
|
|
heterochromatin assembly
|
GO:0031507 |
6 |
0.424
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.392
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.391
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.386
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.381
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.333
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.319
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.317
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.312
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.307
|
Fly |
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.274
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.260
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.256
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.237
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.235
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.224
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.207
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.196
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.190
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.183
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.181
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.180
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.178
|
Fly |
|
|
tube development
|
GO:0035295 |
125 |
0.177
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.172
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.163
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.163
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.161
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.159
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.157
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.157
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.157
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.157
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.149
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.145
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.145
|
Human |
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.144
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.143
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.139
|
Fly |
|
|
dna replication
|
GO:0006260 |
116 |
0.137
|
Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.136
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.134
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.130
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.126
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.125
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.124
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.123
|
Fly |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.122
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.122
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.121
|
Worm Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.120
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.113
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.111
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.111
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.110
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.109
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.109
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.109
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.107
|
Human |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.105
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.105
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.104
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.103
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.102
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.101
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.101
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.097
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.097
|
Fly |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.097
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.097
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.096
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.095
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.094
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.093
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.093
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.092
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.091
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.088
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.087
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.086
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.084
|
|
|
|
heterochromatin organization
|
GO:0070828 |
6 |
0.081
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.080
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.080
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.078
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.078
|
Human |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.077
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.077
|
Fly |
|
|
rna stabilization
|
GO:0043489 |
18 |
0.077
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.076
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.076
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.075
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.074
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.072
|
Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.071
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.071
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.070
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.070
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.067
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.066
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.066
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.066
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.066
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.065
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.064
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.064
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.064
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.063
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.063
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.061
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.060
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.060
|
Fly |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.059
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.059
|
Fly |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.059
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.058
|
Human |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.058
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.058
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.058
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.058
|
|
|
|
positive regulation of t helper cell differentiation
|
GO:0045624 |
2 |
0.057
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.057
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.057
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.057
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.056
|
|
|
|
system process
|
GO:0003008 |
349 |
0.054
|
|
|
|
dna methylation or demethylation
|
GO:0044728 |
19 |
0.054
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.054
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.054
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.053
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.053
|
Fly |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.053
|
Human |
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.053
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.052
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.052
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.051
|
Human |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.051
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.051
|
|
|
|
mrna stabilization
|
GO:0048255 |
18 |
0.050
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.050
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.049
|
Worm |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.049
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.049
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.048
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.048
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.048
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.047
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.047
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.047
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.047
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.047
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.046
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.046
|
Fly |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.046
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.046
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.046
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.046
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.045
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.045
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.045
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.044
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.044
|
|
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.044
|
Human |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.044
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.043
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.043
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.043
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.042
|
Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.042
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.042
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.042
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.042
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.042
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.041
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.041
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.041
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.041
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.041
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.040
|
|
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
8 |
0.040
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.040
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.040
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.040
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.040
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.039
|
Fly |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.039
|
|
|
|
mating
|
GO:0007618 |
1 |
0.039
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.039
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.038
|
Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.038
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.038
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.038
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.038
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.038
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.037
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
3 |
0.037
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.037
|
Worm |
|
|
neurological system process
|
GO:0050877 |
163 |
0.036
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.036
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.036
|
Fly |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.036
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.036
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.035
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.035
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.035
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.034
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.034
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.034
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.034
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.034
|
Fly |
|
|
memory
|
GO:0007613 |
3 |
0.034
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.033
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.033
|
Human Mouse |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.033
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.033
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.033
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.033
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.032
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.032
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.032
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.032
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.032
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.032
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.032
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.032
|
Fly |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.032
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.032
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
4 |
0.032
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.031
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.031
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.031
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.031
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.030
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.030
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.030
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.030
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.030
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.030
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.030
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.030
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.030
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.029
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.029
|
|
|
|
histone h3 k9 methylation
|
GO:0051567 |
10 |
0.029
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.029
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.029
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.029
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.029
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.029
|
Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.029
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.029
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.029
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.029
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.029
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
3 |
0.029
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.028
|
Human |
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.028
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.028
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.028
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.028
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.028
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.028
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.027
|
|
|
|
dna modification
|
GO:0006304 |
27 |
0.027
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.027
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.027
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.027
|
|
|
|
regulation of rna stability
|
GO:0043487 |
23 |
0.026
|
Human |
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.026
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.026
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.026
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.026
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.026
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.026
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.026
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.026
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.026
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.025
|
|
|
|
head development
|
GO:0060322 |
108 |
0.025
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.025
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.025
|
|
|
|
erythrocyte development
|
GO:0048821 |
3 |
0.025
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.025
|
Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.025
|
Fly |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.025
|
Fly |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.025
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.025
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.024
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.024
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.024
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.024
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.024
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.024
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.024
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.024
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.024
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.024
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.024
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.024
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.024
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.024
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.024
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.024
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.024
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.024
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.023
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.023
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.023
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.023
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.023
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.023
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.023
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.023
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.023
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.023
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.023
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.023
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.022
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.022
|
|
|
|
dna duplex unwinding
|
GO:0032508 |
30 |
0.022
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.022
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.022
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.022
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.022
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.022
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.022
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.022
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.022
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.022
|
Fly |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.022
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.022
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.022
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.022
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
4 |
0.021
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.021
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.021
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.021
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.021
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.021
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.021
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.021
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.021
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.021
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.021
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.021
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.021
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.021
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.021
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.021
|
|
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.021
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.020
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.020
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.020
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.020
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.020
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.020
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.020
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.020
|
Fly |
|
|
organelle fission
|
GO:0048285 |
149 |
0.020
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.020
|
Fly |
|
|
centromere complex assembly
|
GO:0034508 |
10 |
0.020
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.020
|
Human Fly |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.020
|
|
|
|
positive regulation of histone h3 k9 methylation
|
GO:0051574 |
3 |
0.020
|
|
|
|
translation
|
GO:0006412 |
132 |
0.020
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.020
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.020
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.020
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.020
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.019
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.019
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.019
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.019
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.019
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.019
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.019
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.019
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.019
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.019
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.019
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.019
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.019
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.019
|
Fly |
|
|
citrate metabolic process
|
GO:0006101 |
2 |
0.019
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.019
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.019
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.018
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.018
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.018
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.018
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.018
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.018
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.018
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.018
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.018
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.018
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.018
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.018
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.018
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.018
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.018
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.018
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.018
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.018
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.018
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.017
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.017
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.017
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.017
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.017
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.017
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.017
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.017
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.017
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.017
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.017
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.017
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.017
|
Human |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.016
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.016
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.016
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.016
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.016
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.016
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.016
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.016
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.016
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.016
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.016
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.016
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.016
|
Fly |
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.016
|
|
|
|
cellular response to nerve growth factor stimulus
|
GO:1990090 |
6 |
0.016
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.016
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.015
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.015
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.015
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.015
|
Human |
|
|
spindle assembly involved in mitosis
|
GO:0090307 |
12 |
0.015
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.015
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.015
|
|
|
|
venous blood vessel development
|
GO:0060841 |
2 |
0.015
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.015
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.015
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.015
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.015
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.015
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.015
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.015
|
Fly |
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.015
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.015
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.015
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.015
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.015
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.015
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.015
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.015
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.014
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.014
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.014
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.014
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.014
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.014
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.014
|
|
|
|
chromatin remodeling at centromere
|
GO:0031055 |
2 |
0.014
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.014
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.014
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.014
|
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.014
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.014
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.014
|
|
