|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
1.000
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.997
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.995
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.995
|
|
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.994
|
|
|
|
negative regulation of epidermal cell differentiation
|
GO:0045605 |
4 |
0.976
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.973
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.971
|
Fly |
|
|
methylation
|
GO:0032259 |
106 |
0.959
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
1 |
0.958
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.954
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.953
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.953
|
|
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
32 |
0.946
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.937
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.922
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.920
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.895
|
Mouse Fly |
|
|
negative regulation of epidermis development
|
GO:0045683 |
5 |
0.883
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
90 |
0.882
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.875
|
Mouse Worm Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.852
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.846
|
Mouse Fly |
|
|
gene silencing
|
GO:0016458 |
49 |
0.838
|
Fly |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.834
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.833
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.822
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.812
|
|
|
|
regulation of histone methylation
|
GO:0031060 |
16 |
0.781
|
Mouse Fly |
|
|
mrna splicing via spliceosome
|
GO:0000398 |
89 |
0.751
|
|
|
|
dna methylation or demethylation
|
GO:0044728 |
19 |
0.706
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.701
|
|
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.694
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.685
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.679
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.666
|
Mouse Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.641
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.639
|
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.630
|
Mouse |
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.617
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.616
|
|
|
|
maintenance of dna methylation
|
GO:0010216 |
3 |
0.611
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.603
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.595
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.572
|
Fly |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.566
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.546
|
Worm |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.540
|
Fly |
|
|
negative regulation of histone methylation
|
GO:0031061 |
6 |
0.537
|
|
|
|
dna hypermethylation
|
GO:0044026 |
1 |
0.532
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.515
|
|
|
|
positive regulation of histone methylation
|
GO:0031062 |
12 |
0.508
|
Mouse Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.500
|
|
|
|
histone h3 k9 modification
|
GO:0061647 |
11 |
0.497
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.494
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.483
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.462
|
|
|
|
negative regulation of histone h3 k9 methylation
|
GO:0051573 |
3 |
0.456
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.455
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.445
|
|
|
|
dna modification
|
GO:0006304 |
27 |
0.445
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
27 |
0.434
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.426
|
|
|
|
alternative mrna splicing via spliceosome
|
GO:0000380 |
27 |
0.411
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.373
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.367
|
|
|
|
negative regulation of dna templated transcription elongation
|
GO:0032785 |
6 |
0.367
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
21 |
0.359
|
|
|
|
nucleosome positioning
|
GO:0016584 |
3 |
0.356
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.338
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.335
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.330
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.324
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.319
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.318
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.314
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.313
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.307
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.305
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.305
|
|
|
|
negative regulation of retinoic acid receptor signaling pathway
|
GO:0048387 |
4 |
0.305
|
|
|
|
positive regulation of histone h3 k4 methylation
|
GO:0051571 |
8 |
0.302
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.300
|
Mouse Fly |
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
89 |
0.299
|
|
|
|
regulation of rna splicing
|
GO:0043484 |
62 |
0.298
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.286
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.271
|
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
5 |
0.260
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.260
|
Mouse Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.260
|
Worm |
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.246
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.237
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.235
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.233
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.231
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.218
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.216
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.215
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.206
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.203
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
25 |
0.199
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.195
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.194
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.192
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.191
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.190
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.185
|
|
|
|
histone h3 k9 methylation
|
GO:0051567 |
10 |
0.184
|
|
|
|
regulation of alternative mrna splicing via spliceosome
|
GO:0000381 |
22 |
0.179
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.174
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.169
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.167
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.167
|
Fly |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.161
|
Fly |
|
|
response to wounding
|
GO:0009611 |
168 |
0.161
|
|
|
|
dna alkylation
|
GO:0006305 |
7 |
0.160
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.157
|
Fly |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.157
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.154
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.151
|
Mouse Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.148
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.146
|
|
|
|
rrna processing
|
GO:0006364 |
35 |
0.146
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.143
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.141
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.139
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.132
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.132
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.131
|
Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.129
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.127
|
|
|
|
negative regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034244 |
4 |
0.126
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.118
|
|
|
|
growth
|
GO:0040007 |
202 |
0.115
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
53 |
0.113
|
|
|
|
regulation of histone h3 k4 methylation
|
GO:0051569 |
10 |
0.113
|
|
|
|
dna methylation
|
GO:0006306 |
7 |
0.110
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.103
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.102
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.100
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.100
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.099
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.098
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.098
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.096
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.094
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
29 |
0.092
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
11 |
0.091
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.091
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.088
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.087
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.086
|
Fly |
|
|
negative regulation of epithelial cell differentiation
|
GO:0030857 |
6 |
0.086
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.084
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.082
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.078
|
Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.078
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.078
|
|
|
|
ribosome biogenesis
|
GO:0042254 |
48 |
0.077
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.077
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.076
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.075
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.074
|
|
|
|
regulation of protein acetylation
|
GO:1901983 |
25 |
0.074
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.073
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.072
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.070
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.069
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.069
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.066
|
|
|
|
establishment of rna localization
|
GO:0051236 |
39 |
0.066
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.064
|
|
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
18 |
0.064
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.063
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.062
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.062
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.062
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.061
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.061
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.060
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.060
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.060
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.059
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.059
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.059
|
Fly |
|
|
digestive system development
|
GO:0055123 |
75 |
0.059
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.058
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.057
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.057
|
|
|
|
response to amino acid
|
GO:0043200 |
14 |
0.057
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.056
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.055
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.054
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.054
|
Mouse Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.053
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.053
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.052
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.052
|
|
|
|
dna methylation on cytosine
|
GO:0032776 |
3 |
0.052
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.051
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.050
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.050
|
Worm |
|
|
gene silencing by rna
|
GO:0031047 |
26 |
0.049
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.049
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.049
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.049
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.048
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.048
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.047
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.047
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.047
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.046
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.046
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.044
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.044
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.043
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.043
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
23 |
0.043
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.043
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.042
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.042
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.041
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.041
|
Fly |
|
|
muscle organ development
|
GO:0007517 |
56 |
0.040
|
Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.040
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.040
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.039
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.039
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.039
|
Mouse Fly |
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.039
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.039
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.038
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.038
|
Mouse Fly |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.038
|
|
|
|
regulation of histone h3 k27 methylation
|
GO:0061085 |
4 |
0.037
|
Mouse |
|
|
cell activation
|
GO:0001775 |
213 |
0.037
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.037
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.037
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.037
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.037
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.036
|
|
|
|
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna
|
GO:0000466 |
2 |
0.036
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.036
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.036
|
|
|
|
regulation of dna methylation
|
GO:0044030 |
2 |
0.036
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
30 |
0.036
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.036
|
|
|
|
rna transport
|
GO:0050658 |
39 |
0.036
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.035
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.035
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.035
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.035
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.035
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.035
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.034
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.034
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.034
|
Fly |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.033
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.032
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.032
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.031
|
|
|
|
rrna metabolic process
|
GO:0016072 |
40 |
0.031
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.031
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.031
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.030
|
|
|
|
regulation of transcription by chromatin organization
|
GO:0034401 |
1 |
0.030
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.030
|
Worm |
|
|
response to testosterone
|
GO:0033574 |
1 |
0.030
|
|
|
|
histone h2a monoubiquitination
|
GO:0035518 |
11 |
0.030
|
|
|
|
regulation of gene expression by genetic imprinting
|
GO:0006349 |
1 |
0.029
|
Mouse |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.029
|
|
|
|
regulation of retinoic acid receptor signaling pathway
|
GO:0048385 |
9 |
0.029
|
|
|
|
rna export from nucleus
|
GO:0006405 |
33 |
0.029
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.028
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.028
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.028
|
|
|
|
negative regulation of mrna splicing via spliceosome
|
GO:0048025 |
11 |
0.028
|
|
|
|
cellular response to dexamethasone stimulus
|
GO:0071549 |
1 |
0.028
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.028
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.027
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.027
|
|
|
|
negative regulation of histone modification
|
GO:0031057 |
19 |
0.027
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.027
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
8 |
0.026
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.026
|
Mouse Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.026
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.026
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.026
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.026
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.026
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.025
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.025
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.025
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.025
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.025
|
|
|
|
response to heat
|
GO:0009408 |
21 |
0.025
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.025
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
15 |
0.025
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.025
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.025
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.025
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.024
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.024
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.024
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.024
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.024
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.024
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.024
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.023
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.023
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.023
|
|
|
|
negative regulation of mrna processing
|
GO:0050686 |
12 |
0.023
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.023
|
Fly |
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.023
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.023
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.022
|
|
|
|
g1 to g0 transition
|
GO:0070314 |
2 |
0.022
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.022
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.022
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
37 |
0.022
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.022
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.022
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.022
|
|
|
|
dosage compensation
|
GO:0007549 |
3 |
0.022
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.022
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.022
|
Worm |
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.022
|
Fly |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.021
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.021
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.021
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.021
|
|
|
|
gamete generation
|
GO:0007276 |
25 |
0.021
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.021
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.021
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.021
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.020
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.020
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.020
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.020
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.020
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.020
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.019
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
35 |
0.019
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.019
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.019
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.019
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.019
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.019
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.019
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.019
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.019
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.019
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.018
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.018
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.018
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.018
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.018
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.018
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.018
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.018
|
|
|
|
ribosome localization
|
GO:0033750 |
4 |
0.018
|
|
|
|
nucleic acid transport
|
GO:0050657 |
39 |
0.017
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.017
|
|
|
|
histone h4 deacetylation
|
GO:0070933 |
8 |
0.017
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.017
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.017
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.017
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.017
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.017
|
|
|
|
maturation of ssu rrna
|
GO:0030490 |
3 |
0.016
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.016
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.016
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.016
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.016
|
|
|
|
prostanoid metabolic process
|
GO:0006692 |
17 |
0.016
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.016
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.016
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.016
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.016
|
|
|
|
negative regulation of rna splicing
|
GO:0033119 |
15 |
0.015
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
25 |
0.015
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.015
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.015
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.015
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.015
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.015
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.015
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.015
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.015
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.015
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.015
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.015
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.015
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.014
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.014
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.014
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
37 |
0.014
|
Fly |
|
|
transcription from rna polymerase i promoter
|
GO:0006360 |
11 |
0.014
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.014
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.014
|
|
|
|
positive regulation of chromatin silencing
|
GO:0031937 |
3 |
0.014
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.014
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.014
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.014
|
|
|
|
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna
|
GO:0000462 |
1 |
0.014
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.014
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.014
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.014
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.014
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.014
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.014
|
|
|
|
negative regulation of striated muscle cell differentiation
|
GO:0051154 |
8 |
0.014
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.014
|
|
|
|
unsaturated fatty acid biosynthetic process
|
GO:0006636 |
21 |
0.013
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.013
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.013
|
|
|
|
aging
|
GO:0007568 |
66 |
0.013
|
|
|
|
maturation of lsu rrna
|
GO:0000470 |
3 |
0.013
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.013
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.013
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.013
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.013
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.013
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.013
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.012
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
23 |
0.012
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.012
|
|
|
|
rna polyadenylation
|
GO:0043631 |
14 |
0.012
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.012
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.012
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.012
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.012
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.012
|
Fly |
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.012
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.011
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.011
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.011
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.011
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.011
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.011
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.011
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.011
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.011
|
|
|
|
regulation of oxidative stress induced neuron death
|
GO:1903203 |
9 |
0.011
|
|
|
|
atp dependent chromatin remodeling
|
GO:0043044 |
25 |
0.011
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.011
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.011
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.010
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.010
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
15 |
0.010
|
|
|
|
maintenance of dna repeat elements
|
GO:0043570 |
4 |
0.010
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.010
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.010
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.010
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.010
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.010
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.010
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.010
|
|
|
|
mrna transport
|
GO:0051028 |
30 |
0.010
|
|
|
|
nuclear pore complex assembly
|
GO:0051292 |
7 |
0.010
|
|
