|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.802
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.614
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.601
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.586
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.574
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.565
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.543
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.531
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.516
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.498
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.469
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.463
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.457
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.432
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.431
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.420
|
|
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
14 |
0.418
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.411
|
Human |
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.410
|
Human |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.404
|
Human |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.401
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.388
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.385
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.380
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.373
|
Human |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.367
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.367
|
Human |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.366
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.361
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.361
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.350
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.350
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.337
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.337
|
Human |
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.333
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.332
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.327
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.322
|
Human |
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.314
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.312
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.311
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.309
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.306
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.304
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.295
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.294
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.292
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.289
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.287
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.286
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.285
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.285
|
Human |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.285
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.284
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.278
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.278
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.277
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.277
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.277
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.274
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.273
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.273
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.273
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.270
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.269
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.262
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.261
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.257
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.257
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.255
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.250
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.247
|
Human |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.247
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.246
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.245
|
Human |
|
|
tube development
|
GO:0035295 |
125 |
0.245
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.243
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.242
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.242
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.240
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.239
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.237
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.237
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.235
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.234
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.231
|
Human |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.228
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.228
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.227
|
Human |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.227
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.224
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.223
|
Human |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.223
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.222
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.221
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.221
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.220
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.220
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.218
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.218
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.217
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.216
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.216
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.216
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.215
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.214
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.214
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.209
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.208
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.208
|
Human |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.208
|
Human |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.206
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.196
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.195
|
Human |
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.192
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.192
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.190
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.190
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.190
|
Human |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.190
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.187
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.186
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.186
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.186
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.186
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.186
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.185
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.182
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.180
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.176
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.175
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.174
|
Human |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.174
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.172
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.171
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.170
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.168
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.166
|
Human |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.165
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.164
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.161
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.160
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.158
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.156
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.155
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.151
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.149
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.148
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.148
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.145
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.144
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.143
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.143
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.142
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.141
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.141
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.140
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.139
|
|
|
|
positive regulation of rho guanyl nucleotide exchange factor activity
|
GO:2001108 |
1 |
0.137
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.136
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.136
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.133
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.131
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.129
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.128
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.127
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.127
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.127
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.126
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.125
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.125
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.124
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.123
|
Human |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.121
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.120
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.120
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.119
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.118
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.118
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.117
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.117
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.117
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.116
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.116
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.113
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.113
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.112
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.112
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.109
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.108
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.108
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.107
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.107
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.107
|
Human |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.104
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.104
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.104
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.103
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.102
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.102
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.101
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.099
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.098
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.096
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.095
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.094
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.094
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.094
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.093
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.092
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.090
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.089
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.088
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.088
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.087
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.087
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.086
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.085
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.084
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.083
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.083
|
|
|
|
regulation of rho guanyl nucleotide exchange factor activity
|
GO:2001106 |
1 |
0.083
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.082
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.082
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.082
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.081
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.081
|
|
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.081
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.080
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.079
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.078
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.077
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.076
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.075
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.074
|
|
|
|
system process
|
GO:0003008 |
349 |
0.074
|
|
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.074
|
Human |
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.073
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.073
|
|
|
|
regulation of cdc42 gtpase activity
|
GO:0043088 |
10 |
0.073
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.073
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.073
|
|
|
|
secondary metabolic process
|
GO:0019748 |
17 |
0.072
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.072
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.070
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.070
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.070
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.068
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.068
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.068
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.068
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.068
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.068
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.067
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.066
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.065
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.064
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.062
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.062
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.061
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.061
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.060
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.060
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.060
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.060
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.060
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.059
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.059
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.058
|
Human |
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.058
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.057
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.057
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.057
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.056
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.055
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.054
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.053
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.052
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.051
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.050
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.049
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.049
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.048
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.048
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.048
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.048
|
|
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.048
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.047
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.047
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.047
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.047
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.046
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.046
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.046
|
|
|
|
head development
|
GO:0060322 |
108 |
0.046
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.046
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.045
|
Human |
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.044
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.044
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.044
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.044
|
|
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.044
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.044
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.043
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.043
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.043
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.042
|
Human |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.042
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.042
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.042
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.041
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.040
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.040
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.039
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.039
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.039
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.039
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.038
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.038
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.038
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.038
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.038
|
|
|
|
regulation of rac gtpase activity
|
GO:0032314 |
4 |
0.038
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.037
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.037
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.037
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.036
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.036
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.036
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.036
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.036
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.036
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.036
|
|
|
|
vasculogenesis
|
GO:0001570 |
8 |
0.036
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.035
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.035
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.035
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.035
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.035
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.034
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.034
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.034
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.034
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.034
|
|
|
|
positive regulation of protein localization to plasma membrane
|
GO:1903078 |
20 |
0.034
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.034
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.034
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.034
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.034
|
|
|
|
negative regulation of cytolysis
|
GO:0045918 |
3 |
0.034
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.033
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.033
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.033
|
|
|
|
positive regulation of establishment of protein localization to plasma membrane
|
GO:0090004 |
18 |
0.033
|
|
|
|
mhc class ii biosynthetic process
|
GO:0045342 |
4 |
0.032
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.032
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.032
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.032
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.032
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.032
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.032
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.032
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.032
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.032
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.032
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.031
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.031
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.031
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.031
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.031
|
|
|
|
regulation of hematopoietic progenitor cell differentiation
|
GO:1901532 |
24 |
0.031
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.031
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.030
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.030
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.030
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.030
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.030
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.030
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.030
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.030
|
|
|
|
lens fiber cell differentiation
|
GO:0070306 |
2 |
0.030
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.030
|
|
|
|
mammary gland development
|
GO:0030879 |
17 |
0.030
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.030
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.029
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.029
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.029
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.029
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.029
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.029
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.029
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.029
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.028
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.028
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.028
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.028
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.028
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.028
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.028
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.028
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.028
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.028
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.027
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.027
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.027
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.027
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.027
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.027
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.027
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.027
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.027
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.027
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.027
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.027
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.026
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.026
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.026
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.026
|
Human |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.026
|
|
|
|
regulation of lamellipodium organization
|
GO:1902743 |
19 |
0.026
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.026
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.026
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.025
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.025
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.025
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.025
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.025
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.025
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.025
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.025
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.025
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.025
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.025
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.025
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.024
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.024
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.024
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.024
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.024
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.024
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.024
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.024
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.024
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.024
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.024
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.024
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.023
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.023
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.023
|
Human |
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.023
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.023
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.023
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.023
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.023
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.023
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.023
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.023
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.023
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.023
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.023
|
|
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.023
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.022
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.022
|
Human |
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.022
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.022
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.022
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.022
|
|
|
|
activation of ras gtpase activity
|
GO:0032856 |
15 |
0.022
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.022
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.022
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.022
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.022
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.022
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.021
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.021
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.021
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.021
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.021
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.021
|
|
|
|
negative regulation of epidermal cell differentiation
|
GO:0045605 |
4 |
0.021
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.021
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.021
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.021
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.021
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.021
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.021
|
|
