|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.937
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.818
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.777
|
Human |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.733
|
Human |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.721
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.713
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.697
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.675
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.638
|
Human |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.607
|
Human |
|
|
protein targeting to membrane
|
GO:0006612 |
42 |
0.567
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.546
|
Human |
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.482
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.464
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.458
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.435
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.424
|
Human |
|
|
heart contraction
|
GO:0060047 |
62 |
0.393
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.378
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.370
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.366
|
|
|
|
endocytic recycling
|
GO:0032456 |
12 |
0.353
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.341
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.308
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.306
|
Fly |
|
|
endosome localization
|
GO:0032439 |
2 |
0.296
|
|
|
|
regulation of cardiac muscle contraction by calcium ion signaling
|
GO:0010882 |
3 |
0.289
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.289
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.284
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.280
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.252
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.252
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.237
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.216
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.209
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.209
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.205
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.203
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.199
|
Worm |
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.195
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.184
|
|
|
|
golgi to vacuole transport
|
GO:0006896 |
3 |
0.172
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.167
|
Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.166
|
Fly |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.165
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.165
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.165
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.161
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.161
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.157
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.150
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.150
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.149
|
Worm |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.142
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.140
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.140
|
Mouse |
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.138
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.135
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.131
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.131
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.131
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.130
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.129
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.128
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.127
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.126
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.125
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.122
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.115
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.115
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.115
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.115
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.109
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.107
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.107
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.102
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.101
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.099
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.097
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.096
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.096
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.095
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.094
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.094
|
|
|
|
pinocytosis
|
GO:0006907 |
8 |
0.093
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.092
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.092
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.092
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.092
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.091
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.091
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.090
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.090
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.089
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.089
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.089
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.087
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.086
|
Worm |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.085
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.085
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.085
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.084
|
|
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
0.084
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.084
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.083
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.083
|
|
|
|
protein targeting to plasma membrane
|
GO:0072661 |
13 |
0.082
|
Human |
|
|
cardiac atrium development
|
GO:0003230 |
10 |
0.082
|
|
|
|
atrial septum development
|
GO:0003283 |
8 |
0.082
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.081
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.080
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.080
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.079
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.079
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.079
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.079
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.077
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.075
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.075
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.075
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.075
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.074
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.074
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.073
|
Worm |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.071
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.071
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.071
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.071
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.070
|
Worm |
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.069
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.067
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.067
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.067
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.067
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.067
|
|
|
|
system process
|
GO:0003008 |
349 |
0.067
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.066
|
Worm |
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.065
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.064
|
Worm |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.064
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.063
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.063
|
|
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.063
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.062
|
Mouse Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.062
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.062
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.062
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.062
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.061
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.061
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.061
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.061
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.060
|
|
|
|
nadph oxidation
|
GO:0070995 |
3 |
0.060
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.060
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.060
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.059
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.059
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.059
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.058
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.058
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.058
|
Worm |
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.058
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.058
|
Mouse |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.057
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.057
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.056
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.056
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.056
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.056
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.055
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.054
|
|
|
|
sarcoplasmic reticulum calcium ion transport
|
GO:0070296 |
13 |
0.054
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.054
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.053
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.053
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.053
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.053
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.053
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.052
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.052
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.052
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.051
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.051
|
Worm |
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.051
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.051
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.051
|
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
36 |
0.051
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.051
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.050
|
|
|
|
sa node cell to atrial cardiac muscle cell communication
|
GO:0086070 |
3 |
0.050
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.050
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.050
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.050
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.049
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.049
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.049
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.049
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.049
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.049
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.048
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.048
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.048
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.047
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.047
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.047
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.047
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.047
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.047
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.047
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.046
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.046
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.046
|
Worm |
|
|
endoplasmic reticulum to cytosol transport
|
GO:1903513 |
13 |
0.046
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.046
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.045
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.045
|
Mouse |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.045
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.045
|
Worm |
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.044
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.044
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.044
|
|
|
|
regulation of ventricular cardiac muscle cell membrane repolarization
|
GO:0060307 |
10 |
0.043
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.043
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.043
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.042
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.042
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.042
|
|
|
|
maintenance of protein location in plasma membrane
|
GO:0072660 |
1 |
0.042
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.042
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.041
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.041
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.041
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.041
|
Worm |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.041
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.041
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.041
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.041
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.041
|
Fly |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.040
|
|
|
|
er to golgi vesicle mediated transport
|
GO:0006888 |
19 |
0.040
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.040
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.040
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.039
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.039
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.039
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.038
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.038
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.038
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.038
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.037
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.037
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.037
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.037
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.037
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.036
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.036
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.036
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.036
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.036
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.036
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.035
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.035
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.035
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.035
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.035
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.035
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.034
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.034
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.034
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.034
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.034
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.034
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.034
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.034
|
Mouse |
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.034
|
|
|
|
endosomal vesicle fusion
|
GO:0034058 |
1 |
0.034
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.034
|
Worm |
|
|
calcium ion transport from endoplasmic reticulum to cytosol
|
GO:1903514 |
13 |
0.034
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.033
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.033
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.033
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.033
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.033
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
41 |
0.033
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.033
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.032
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.032
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.032
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.032
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.032
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.031
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.031
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.031
|
Worm |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.031
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.031
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.031
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.031
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.031
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.030
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.030
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.030
|
|
|
|
leukocyte aggregation
|
GO:0070486 |
8 |
0.030
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.030
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.030
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.029
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.029
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.029
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.029
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.029
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.029
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.028
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.028
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.028
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.028
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.028
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.028
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.028
|
Worm |
|
|
regulation of actin filament based movement
|
GO:1903115 |
24 |
0.028
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.028
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.028
|
|
|
|
atrial cardiac muscle cell to av node cell communication
|
GO:0086066 |
6 |
0.027
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.027
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.027
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.027
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.027
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.027
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.027
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.027
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.027
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.027
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.026
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.026
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.026
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.026
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.026
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.026
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.026
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.026
|
Worm |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.026
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.026
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.026
|
|
|
|
vesicle fusion
|
GO:0006906 |
17 |
0.026
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.026
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.025
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.025
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.025
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.025
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.025
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.025
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.025
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.025
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.025
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.025
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.025
|
Mouse |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.025
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.025
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.025
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.025
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.025
|
|
|
|
regulation of pinocytosis
|
GO:0048548 |
6 |
0.025
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.024
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.024
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.024
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.024
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.024
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.024
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.024
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.024
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.024
|
Worm |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.024
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.024
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.024
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.024
|
Worm |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.024
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.024
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.023
|
|
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
23 |
0.023
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.023
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.023
|
|
|
|
membrane tubulation
|
GO:0097320 |
12 |
0.023
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.023
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.023
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.023
|
|
|
|
p38mapk cascade
|
GO:0038066 |
9 |
0.023
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.023
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
37 |
0.023
|
|
|
|
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
|
GO:0014808 |
13 |
0.023
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.023
|
Worm |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.023
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.022
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.022
|
Worm |
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.022
|
|
|
|
regulation of cardiac muscle cell membrane potential
|
GO:0086036 |
1 |
0.022
|
Human |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.022
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.022
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.022
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.022
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.022
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.022
|
Worm |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.022
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.022
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.022
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.021
|
Mouse |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.021
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.021
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.021
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.021
|
|
|
|
regulation of heart rate by cardiac conduction
|
GO:0086091 |
19 |
0.021
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.021
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.021
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.021
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.021
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.021
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.021
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.021
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.021
|
Fly |
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.020
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.020
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.020
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.020
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.020
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.020
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.020
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.020
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.020
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.020
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.020
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.020
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.019
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.019
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.019
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.019
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.019
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.018
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.018
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.018
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.018
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.018
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.018
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.018
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.018
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.018
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.018
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.018
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.017
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.017
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.017
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.017
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.017
|
Mouse |
|
|
cardiac conduction
|
GO:0061337 |
23 |
0.017
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.017
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.017
|
Worm |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.017
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.017
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.017
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.016
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.016
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.016
|
Worm |
|
|
regulation of release of sequestered calcium ion into cytosol
|
GO:0051279 |
27 |
0.016
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.016
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.016
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.016
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.016
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.016
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.016
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.016
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.016
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.016
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.016
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.016
|
|
|
|
protein depolymerization
|
GO:0051261 |
30 |
0.016
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.016
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.016
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.016
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.015
|
Mouse |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.015
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.015
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.015
|
|
|
|
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
|
GO:0010881 |
2 |
0.015
|
|
|
|
lymphocyte aggregation
|
GO:0071593 |
1 |
0.015
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.015
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.015
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.015
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.015
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.015
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.015
|
|
