Homo sapiens

25 known processes

EIF3F

eukaryotic translation initiation factor 3, subunit F

(Aliases: EIF3S5,eIF3-p47)

EIF3F biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic translational initiation GO:0002183 6 1.000
translational initiation GO:0006413 48 0.999
regulation of cellular amine metabolic process GO:0033238 11 0.876
female gamete generation GO:0007292 2 0.780
cellular macromolecular complex assembly GO:0034622 324 0.752
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.643
translation GO:0006412 132 0.623
oogenesis GO:0048477 2 0.570
peptidyl tyrosine phosphorylation GO:0018108 170 0.542
protein processing GO:0016485 226 0.534
regulation of apoptotic signaling pathway GO:2001233 175 0.452
formation of translation preinitiation complex GO:0001731 4 0.419
receptor mediated endocytosis GO:0006898 84 0.404
Worm
cellular ketone metabolic process GO:0042180 80 0.371
neuron projection development GO:0031175 106 0.366
ribonucleoprotein complex subunit organization GO:0071826 81 0.349
cell projection organization GO:0030030 252 0.349
cellular component morphogenesis GO:0032989 314 0.325
cellular response to organic cyclic compound GO:0071407 127 0.322
positive regulation of apoptotic process GO:0043065 246 0.316
regulation of endopeptidase activity GO:0052548 170 0.299
protein secretion GO:0009306 98 0.293
protein localization to membrane GO:0072657 160 0.289
neurogenesis GO:0022008 169 0.288
generation of neurons GO:0048699 152 0.280
cell morphogenesis GO:0000902 296 0.278
positive regulation of cellular amine metabolic process GO:0033240 7 0.276
mitotic cell cycle GO:0000278 326 0.275
positive regulation of protein phosphorylation GO:0001934 313 0.274
multicellular organismal aging GO:0010259 3 0.272
Worm
regulation of proteolysis GO:0030162 293 0.254
regulation of muscle system process GO:0090257 53 0.242
neuron differentiation GO:0030182 138 0.238
regulation of cellular ketone metabolic process GO:0010565 50 0.227
neuron development GO:0048666 113 0.223
cellular amino acid metabolic process GO:0006520 116 0.220
cellular response to oxygen containing compound GO:1901701 276 0.218
golgi organization GO:0007030 38 0.214
endomembrane system organization GO:0010256 196 0.206
cellular response to endogenous stimulus GO:0071495 336 0.199
cellular amine metabolic process GO:0044106 41 0.179
response to cytokine GO:0034097 232 0.176
cell part morphogenesis GO:0032990 137 0.176
regulation of protein complex assembly GO:0043254 147 0.172
negative regulation of cellular protein metabolic process GO:0032269 353 0.169
negative regulation of protein maturation GO:1903318 142 0.163
cellular response to glucocorticoid stimulus GO:0071385 4 0.158
regulation of anatomical structure size GO:0090066 101 0.156
regulation of peptidase activity GO:0052547 180 0.153
amine metabolic process GO:0009308 44 0.152
response to organic cyclic compound GO:0014070 204 0.149
microtubule based process GO:0007017 210 0.149
nervous system development GO:0007399 293 0.148
spermatid differentiation GO:0048515 4 0.147
negative regulation of apoptotic process GO:0043066 316 0.147
regulation of cysteine type endopeptidase activity GO:2000116 127 0.144
system process GO:0003008 349 0.143
chromatin organization GO:0006325 351 0.137
actin polymerization or depolymerization GO:0008154 56 0.136
response to dexamethasone GO:0071548 1 0.131
cellular response to hormone stimulus GO:0032870 125 0.130
circulatory system development GO:0072359 262 0.129
mitotic cell cycle process GO:1903047 286 0.124
regulation of cellular component biogenesis GO:0044087 281 0.120
apoptotic signaling pathway GO:0097190 268 0.118
ribonucleoprotein complex assembly GO:0022618 78 0.117
protein modification by small protein conjugation GO:0032446 342 0.115
positive regulation of catabolic process GO:0009896 310 0.114
vesicle mediated transport GO:0016192 371 0.113
Worm
lipid localization GO:0010876 106 0.113
mapk cascade GO:0000165 288 0.111
positive regulation of phosphorylation GO:0042327 394 0.110
cell development GO:0048468 328 0.109
Fly
negative regulation of protein metabolic process GO:0051248 391 0.107
myeloid cell differentiation GO:0030099 117 0.100
nucleotide catabolic process GO:0009166 408 0.099
protein maturation GO:0051604 233 0.099
positive regulation of cellular component organization GO:0051130 376 0.098
protein ubiquitination GO:0016567 314 0.097
regulation of cytoskeleton organization GO:0051493 177 0.094
negative regulation of protein processing GO:0010955 142 0.091
cellular response to lipid GO:0071396 127 0.091
cellular response to steroid hormone stimulus GO:0071383 37 0.091
muscle adaptation GO:0043500 12 0.091
negative regulation of protein modification process GO:0031400 200 0.089
cellular response to abiotic stimulus GO:0071214 117 0.088
positive regulation of cell death GO:0010942 263 0.087
endocytosis GO:0006897 159 0.087
Worm
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.084
nucleoside phosphate catabolic process GO:1901292 412 0.082
regulation of wnt signaling pathway GO:0030111 123 0.080
regulation of cellular amino acid metabolic process GO:0006521 6 0.075
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.074
oocyte differentiation GO:0009994 2 0.074
cell projection morphogenesis GO:0048858 129 0.074
response to hormone GO:0009725 175 0.073
cellular response to dexamethasone stimulus GO:0071549 1 0.073
spermatid development GO:0007286 4 0.073
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.071
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.071
positive regulation of hydrolase activity GO:0051345 331 0.070
positive regulation of peptidase activity GO:0010952 88 0.066
maintenance of location GO:0051235 112 0.063
positive regulation of organelle organization GO:0010638 195 0.062
positive regulation of proteolysis GO:0045862 142 0.062
muscle system process GO:0003012 81 0.060
regulation of system process GO:0044057 101 0.060
oocyte development GO:0048599 1 0.060
peptidyl tyrosine modification GO:0018212 170 0.060
negative regulation of catalytic activity GO:0043086 335 0.059
organophosphate catabolic process GO:0046434 430 0.059
negative regulation of cell differentiation GO:0045596 171 0.059
histone modification GO:0016570 251 0.058
hemopoiesis GO:0030097 180 0.058
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.057
cellular response to corticosteroid stimulus GO:0071384 5 0.056
secretion by cell GO:0032940 226 0.056
negative regulation of programmed cell death GO:0043069 321 0.055
negative regulation of peptidase activity GO:0010466 91 0.054
regulation of actin polymerization or depolymerization GO:0008064 56 0.053
nucleoside triphosphate metabolic process GO:0009141 422 0.053
regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis GO:2001270 3 0.053
positive regulation of programmed cell death GO:0043068 249 0.053
regulation of actin filament length GO:0030832 56 0.053
negative regulation of cell proliferation GO:0008285 228 0.052
neuron projection morphogenesis GO:0048812 50 0.052
mesenchymal cell development GO:0014031 50 0.052
regulation of protein polymerization GO:0032271 63 0.052
protein localization to organelle GO:0033365 280 0.051
glycosyl compound catabolic process GO:1901658 413 0.050
negative regulation of intracellular signal transduction GO:1902532 183 0.050
single organism cellular localization GO:1902580 332 0.048
response to oxygen containing compound GO:1901700 369 0.048
rna processing GO:0006396 255 0.048
negative regulation of multicellular organismal process GO:0051241 317 0.048
negative regulation of phosphorylation GO:0042326 174 0.048
regulation of transferase activity GO:0051338 355 0.048
regulation of actin cytoskeleton organization GO:0032956 116 0.048
cellular protein complex assembly GO:0043623 188 0.047
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.047
leukocyte differentiation GO:0002521 98 0.047
zymogen activation GO:0031638 70 0.047
actin filament polymerization GO:0030041 45 0.046
purine nucleoside triphosphate catabolic process GO:0009146 392 0.046
anatomical structure formation involved in morphogenesis GO:0048646 284 0.046
regulation of myeloid cell differentiation GO:0045637 81 0.046
negative regulation of cell death GO:0060548 345 0.045
immune system development GO:0002520 195 0.045
mrna processing GO:0006397 133 0.045
covalent chromatin modification GO:0016569 254 0.044
ribonucleoside monophosphate metabolic process GO:0009161 187 0.044
regulation of anatomical structure morphogenesis GO:0022603 286 0.042
regulation of actin filament based process GO:0032970 141 0.042
secretion GO:0046903 254 0.042
inositol lipid mediated signaling GO:0048017 55 0.042
negative regulation of hydrolase activity GO:0051346 182 0.042
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.042
regulation of translational initiation GO:0006446 24 0.041
regulation of cell cell adhesion GO:0022407 57 0.041
protein catabolic process GO:0030163 325 0.040
chemical homeostasis GO:0048878 306 0.038
regulation of nucleotide catabolic process GO:0030811 205 0.038
response to steroid hormone GO:0048545 80 0.037
regulation of cell differentiation GO:0045595 393 0.037
microtubule cytoskeleton organization GO:0000226 176 0.036
cellular response to cytokine stimulus GO:0071345 181 0.036
protein polymerization GO:0051258 71 0.036
response to alcohol GO:0097305 64 0.036
i kappab kinase nf kappab signaling GO:0007249 166 0.035
negative regulation of endopeptidase activity GO:0010951 84 0.035
embryo development GO:0009790 123 0.035
Worm
negative regulation of phosphate metabolic process GO:0045936 267 0.034
regulation of leukocyte differentiation GO:1902105 61 0.034
cellular homeostasis GO:0019725 196 0.034
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.033
negative regulation of phosphorus metabolic process GO:0010563 267 0.033
regulation of muscle adaptation GO:0043502 10 0.033
protein modification by small protein removal GO:0070646 92 0.033
ubiquitin dependent protein catabolic process GO:0006511 206 0.033
negative regulation of interleukin 2 production GO:0032703 7 0.033
purine nucleoside monophosphate metabolic process GO:0009126 186 0.033
ion homeostasis GO:0050801 230 0.033
leukocyte activation GO:0045321 164 0.033
cellular lipid metabolic process GO:0044255 303 0.033
nucleoside catabolic process GO:0009164 408 0.032
positive regulation of cellular catabolic process GO:0031331 284 0.032
response to lipid GO:0033993 206 0.032
neural crest cell development GO:0014032 3 0.032
protein kinase b signaling GO:0043491 69 0.031
gtp catabolic process GO:0006184 237 0.030
regulation of protein kinase b signaling GO:0051896 61 0.029
locomotory behavior GO:0007626 1 0.029
signal transduction by phosphorylation GO:0023014 297 0.029
response to ketone GO:1901654 19 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
motor neuron axon guidance GO:0008045 2 0.029
positive regulation of gastrulation GO:2000543 2 0.028
activation of cysteine type endopeptidase activity GO:0097202 57 0.028
embryo development ending in birth or egg hatching GO:0009792 34 0.028
Worm
purine ribonucleoside catabolic process GO:0046130 398 0.028
osteoblast differentiation GO:0001649 92 0.027
ncrna metabolic process GO:0034660 108 0.027
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
tube development GO:0035295 125 0.027
positive regulation of protein kinase b signaling GO:0051897 42 0.027
response to glucocorticoid GO:0051384 13 0.027
actin filament based process GO:0030029 224 0.026
behavior GO:0007610 112 0.026
developmental process involved in reproduction GO:0003006 66 0.026
Worm
negative regulation of protein phosphorylation GO:0001933 140 0.026
negative regulation of kinase activity GO:0033673 106 0.026
regulation of actin filament polymerization GO:0030833 50 0.026
wnt signaling pathway GO:0016055 156 0.025
hematopoietic or lymphoid organ development GO:0048534 186 0.025
regulation of granulocyte differentiation GO:0030852 11 0.025
regulation of protein kinase activity GO:0045859 289 0.025
purine nucleotide catabolic process GO:0006195 405 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
modification dependent protein catabolic process GO:0019941 209 0.025
negative regulation of proteolysis GO:0045861 132 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
positive regulation of cytoskeleton organization GO:0051495 83 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
regulation of protein maturation GO:1903317 150 0.024
positive regulation of cell differentiation GO:0045597 211 0.024
single organism membrane organization GO:0044802 268 0.024
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.024
phosphatidylinositol mediated signaling GO:0048015 55 0.023
negative regulation of developmental process GO:0051093 247 0.023
regulation of chromosome organization GO:0033044 103 0.023
sex differentiation GO:0007548 45 0.022
Worm
cellular component disassembly GO:0022411 92 0.022
multi organism reproductive process GO:0044703 54 0.022
ribonucleotide catabolic process GO:0009261 405 0.021
positive regulation of myeloid cell differentiation GO:0045639 39 0.021
peptidyl lysine modification GO:0018205 144 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.021
determination of adult lifespan GO:0008340 2 0.021
Worm
cell recognition GO:0008037 9 0.021
positive regulation of endopeptidase activity GO:0010950 84 0.021
cytokinesis GO:0000910 96 0.021
sequestering of metal ion GO:0051238 24 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.020
negative regulation of cytokine production GO:0001818 82 0.020
mesenchymal cell differentiation GO:0048762 52 0.020
regulation of protein ubiquitination GO:0031396 95 0.020
cardiovascular system development GO:0072358 262 0.019
cell morphogenesis involved in differentiation GO:0000904 144 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.019
regulation of protein processing GO:0070613 150 0.019
cellular ion homeostasis GO:0006873 168 0.019
protein oligomerization GO:0051259 173 0.019
positive regulation of leukocyte differentiation GO:1902107 37 0.019
cell adhesion GO:0007155 325 0.018
negative regulation of transferase activity GO:0051348 124 0.018
mrna metabolic process GO:0016071 175 0.018
regulation of protein localization GO:0032880 296 0.018
regulation of rna splicing GO:0043484 62 0.018
mrna splicing via spliceosome GO:0000398 89 0.018
pattern specification process GO:0007389 43 0.018
single organism reproductive process GO:0044702 98 0.018
Worm
dna repair GO:0006281 198 0.018
trabecula morphogenesis GO:0061383 2 0.018
negative regulation of cell fate specification GO:0009996 3 0.017
ribose phosphate biosynthetic process GO:0046390 82 0.017
wound healing GO:0042060 115 0.017
ribonucleoprotein complex biogenesis GO:0022613 116 0.017
mitochondrion organization GO:0007005 156 0.017
response to hypoxia GO:0001666 96 0.017
regulation of cellular component size GO:0032535 82 0.017
reproduction GO:0000003 63 0.017
Worm
nucleotide biosynthetic process GO:0009165 109 0.017
regulation of epithelial cell migration GO:0010632 93 0.017
positive regulation of execution phase of apoptosis GO:1900119 5 0.016
sex determination GO:0007530 3 0.016
protein deubiquitination GO:0016579 79 0.016
protein complex disassembly GO:0043241 52 0.016
regulation of feeding behavior GO:0060259 3 0.016
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.016
response to corticosteroid GO:0031960 15 0.016
regulation of cellular response to stress GO:0080135 244 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
cell activation GO:0001775 213 0.016
negative regulation of apoptotic signaling pathway GO:2001234 97 0.016
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.016
protein targeting GO:0006605 187 0.016
regulation of chromosome segregation GO:0051983 44 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
chromosome segregation GO:0007059 114 0.015
carbohydrate metabolic process GO:0005975 207 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
innate immune response GO:0045087 178 0.015
cellular amide metabolic process GO:0043603 69 0.015
interleukin 8 production GO:0032637 51 0.015
peptidyl serine modification GO:0018209 106 0.015
nucleic acid transport GO:0050657 39 0.015
reproductive process GO:0022414 106 0.015
Worm
cellular metal ion homeostasis GO:0006875 146 0.015
cell cycle checkpoint GO:0000075 117 0.014
canonical wnt signaling pathway GO:0060070 116 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
epithelium development GO:0060429 227 0.014
organ morphogenesis GO:0009887 147 0.014
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.014
regulation of kinase activity GO:0043549 314 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
negative regulation of locomotion GO:0040013 118 0.014
positive regulation of transport GO:0051050 336 0.014
regulation of oxidoreductase activity GO:0051341 43 0.014
single organism cell adhesion GO:0098602 179 0.014
cellular chemical homeostasis GO:0055082 180 0.014
cofactor biosynthetic process GO:0051188 31 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
convergent extension GO:0060026 1 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
response to inorganic substance GO:0010035 127 0.013
microtubule polymerization or depolymerization GO:0031109 37 0.013
response to abiotic stimulus GO:0009628 336 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
regulation of multi organism process GO:0043900 157 0.013
stem cell development GO:0048864 69 0.013
regulation of intracellular transport GO:0032386 195 0.013
regulation of response to external stimulus GO:0032101 222 0.013
establishment or maintenance of cell polarity GO:0007163 31 0.013
negative regulation of dna metabolic process GO:0051053 57 0.013
rna splicing GO:0008380 131 0.013
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.013
immune response GO:0006955 307 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
negative regulation of cell cycle phase transition GO:1901988 89 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
regulation of cell growth GO:0001558 135 0.012
negative regulation of cell cell adhesion GO:0022408 27 0.012
purine nucleotide biosynthetic process GO:0006164 84 0.012
spermatogenesis GO:0007283 22 0.012
cation homeostasis GO:0055080 189 0.012
anterior posterior axis specification GO:0009948 2 0.012
developmental growth GO:0048589 48 0.012
intracellular mrna localization GO:0008298 1 0.012
cell growth GO:0016049 160 0.012
cell fate determination GO:0001709 3 0.012
defense response to other organism GO:0098542 129 0.012
regulation of hemoglobin biosynthetic process GO:0046984 1 0.012
trna metabolic process GO:0006399 35 0.012
cell projection assembly GO:0030031 126 0.012
actin cytoskeleton organization GO:0030036 207 0.012
regulation of microtubule based process GO:0032886 74 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
negative regulation of organelle organization GO:0010639 126 0.012
multi organism cellular process GO:0044764 156 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
cyclic nucleotide catabolic process GO:0009214 9 0.012
regulation of proteasomal protein catabolic process GO:0061136 87 0.012
rna modification GO:0009451 27 0.011
organelle assembly GO:0070925 176 0.011
response to external biotic stimulus GO:0043207 261 0.011
regulation of mapk cascade GO:0043408 262 0.011
autophagy GO:0006914 88 0.011
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.011
regulation of stress activated mapk cascade GO:0032872 84 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
macromolecular complex disassembly GO:0032984 60 0.011
nucleobase containing compound transport GO:0015931 51 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
rna interference GO:0016246 4 0.011
cell aging GO:0007569 52 0.011
intracellular protein transport GO:0006886 270 0.011
mitochondrial membrane organization GO:0007006 40 0.011
cellular response to biotic stimulus GO:0071216 71 0.011
single organismal cell cell adhesion GO:0016337 148 0.011
protein homooligomerization GO:0051260 100 0.011
regulation of membrane potential GO:0042391 95 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
mitotic spindle elongation GO:0000022 4 0.011
growth GO:0040007 202 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
ribosome biogenesis GO:0042254 48 0.011
embryonic hindlimb morphogenesis GO:0035116 2 0.011
metal ion homeostasis GO:0055065 169 0.011
protein acetylation GO:0006473 116 0.011
cell fate commitment involved in pattern specification GO:0060581 1 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
execution phase of apoptosis GO:0097194 32 0.010
regulation of cellular protein catabolic process GO:1903362 96 0.010
regulation of microtubule cytoskeleton organization GO:0070507 61 0.010
regulation of protein catabolic process GO:0042176 155 0.010
positive regulation of immune system process GO:0002684 283 0.010
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.010
gtp metabolic process GO:0046039 239 0.010
positive regulation of cell growth GO:0030307 48 0.010
muscle cell cellular homeostasis GO:0046716 3 0.010
multicellular organism reproduction GO:0032504 42 0.010
peptidyl lysine acetylation GO:0018394 101 0.010
establishment of cell polarity GO:0030010 22 0.010
regulation of response to biotic stimulus GO:0002831 55 0.010
cellular response to nutrient levels GO:0031669 69 0.010
protein localization to plasma membrane GO:0072659 93 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
protein acylation GO:0043543 138 0.010
membrane organization GO:0061024 292 0.010
oxidation reduction process GO:0055114 396 0.010
sensory organ development GO:0007423 52 0.010

EIF3F disease predictions

Disease DO term ID Size Probability Func Analog Org